MeSH term | MeSH ID | Detail |
---|---|---|
Vitamin K Deficiency | D014813 | 5 associated lipids |
Thromboembolism | D013923 | 6 associated lipids |
Exanthema | D005076 | 11 associated lipids |
Phylloquinone is a lipid of Prenol Lipids (PR) class. Phylloquinone is associated with abnormalities such as Vitamin K Deficiency, Malnutrition, Consumption-archaic term for TB, Osteoporosis and Hyperostosis, Diffuse Idiopathic Skeletal. The involved functions are known as Ingestion, Blood Circulation, Genetic Polymorphism, Intestinal Absorption and Process. Phylloquinone often locates in Blood, Body tissue, Hepatic, Membrane and Entire bony skeleton. The associated genes with phylloquinone are Vitamin K Epoxide Reductase Complex, Subunit 1, GGCX gene, CYP4F2 gene, Alleles and APOE gene. The related lipids are Micelles, 208-G, Fatty Acids, Total cholesterol and Sphingolipids. The related experimental models are Knock-out.
To understand associated biological information of phylloquinone, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
phylloquinone is suspected in Vitamin K Deficiency, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes, vitamin depletion, Malnutrition, Osteoporosis and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with phylloquinone
MeSH term | MeSH ID | Detail |
---|---|---|
Vitamin K Deficiency | D014813 | 5 associated lipids |
Thromboembolism | D013923 | 6 associated lipids |
Exanthema | D005076 | 11 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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Knock-out are used in the study 'A dedicated thioesterase of the Hotdog-fold family is required for the biosynthesis of the naphthoquinone ring of vitamin K1.' (Widhalm JR et al., 2009) and Knock-out are used in the study 'Deficiency in phylloquinone (vitamin K1) methylation affects prenyl quinone distribution, photosystem I abundance, and anthocyanin accumulation in the Arabidopsis AtmenG mutant.' (Lohmann A et al., 2006).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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von Kries R | Oral versus intramuscular phytomenadione: safety and efficacy compared. | 1999 | Drug Saf | pmid:10433349 |
Wong DA and Freeman S | Cutaneous allergic reaction to intramuscular vitamin K1. | 1999 | Australas. J. Dermatol. | pmid:10439527 |
Joliot P and Joliot A | In vivo analysis of the electron transfer within photosystem I: are the two phylloquinones involved? | 1999 | Biochemistry | pmid:10460169 |
Neguin C et al. | [Voluntary poisoning with a rodenticide in an adolescent]. | 1999 | Arch Pediatr | pmid:10472397 |
Petrus DJ and Henik RA | Pericardial effusion and cardiac tamponade secondary to brodifacoum toxicosis in a dog. | 1999 | J. Am. Vet. Med. Assoc. | pmid:10476710 |
Booth SL et al. | Response of vitamin K status to different intakes and sources of phylloquinone-rich foods: comparison of younger and older adults. | 1999 | Am. J. Clin. Nutr. | pmid:10479199 |
Booth SL et al. | Assessment of phylloquinone and dihydrophylloquinone dietary intakes among a nationally representative sample of US consumers using 14-day food diaries. | 1999 | J Am Diet Assoc | pmid:10491675 |
Cham BE et al. | Interdependence of serum concentrations of vitamin K1, vitamin E, lipids, apolipoprotein A1, and apolipoprotein B: importance in assessing vitamin status. | 1999 | Clin. Chim. Acta | pmid:10509895 |
Chase GW et al. | Liquid chromatographic analysis of vitamin K1 in milk-based infant formula with matrix solid-phase dispersion. | 1999 Sep-Oct | J AOAC Int | pmid:10513014 |
Williams AF | The vitamin K debacle. | 1999 | Arch. Dis. Child. | pmid:10523254 |