phylloquinone

Phylloquinone is a lipid of Prenol Lipids (PR) class. Phylloquinone is associated with abnormalities such as Vitamin K Deficiency, Malnutrition, Consumption-archaic term for TB, Osteoporosis and Hyperostosis, Diffuse Idiopathic Skeletal. The involved functions are known as Ingestion, Blood Circulation, Genetic Polymorphism, Intestinal Absorption and Process. Phylloquinone often locates in Blood, Body tissue, Hepatic, Membrane and Entire bony skeleton. The associated genes with phylloquinone are Vitamin K Epoxide Reductase Complex, Subunit 1, GGCX gene, CYP4F2 gene, Alleles and APOE gene. The related lipids are Micelles, 208-G, Fatty Acids, Total cholesterol and Sphingolipids. The related experimental models are Knock-out.

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Introduction

To understand associated biological information of phylloquinone, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with phylloquinone?

phylloquinone is suspected in Vitamin K Deficiency, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes, vitamin depletion, Malnutrition, Osteoporosis and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with phylloquinone

MeSH term MeSH ID Detail
Exanthema D005076 11 associated lipids
Thromboembolism D013923 6 associated lipids
Vitamin K Deficiency D014813 5 associated lipids
Total 3

PubChem Associated disorders and diseases

What pathways are associated with phylloquinone

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with phylloquinone?

Related references are published most in these journals:

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What functions are associated with phylloquinone?


Related references are published most in these journals:

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What lipids are associated with phylloquinone?

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What genes are associated with phylloquinone?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with phylloquinone?

Knock-out

Knock-out are used in the study 'A dedicated thioesterase of the Hotdog-fold family is required for the biosynthesis of the naphthoquinone ring of vitamin K1.' (Widhalm JR et al., 2009) and Knock-out are used in the study 'Deficiency in phylloquinone (vitamin K1) methylation affects prenyl quinone distribution, photosystem I abundance, and anthocyanin accumulation in the Arabidopsis AtmenG mutant.' (Lohmann A et al., 2006).

Related references are published most in these journals:

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NCBI Entrez Crosslinks

All references with phylloquinone

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Authors Title Published Journal PubMed Link
ASANO A et al. The new synthetic 6-chromanyl phosphate of vitamin K1(20) and its behavior in an enzymatic system from Mycobacterium phlei. 1962 J. Biol. Chem. pmid:13862733
GUSTAFSSON BE et al. Effects of vitamin K-active compounds and intestinal microorganisms in vitamin K-deficient germfree rats. 1962 J. Nutr. pmid:13951405
BARNHART MI and ANDERSON GF Cellular study of drug alteration of prothrombin synthesis. 1962 Biochem. Pharmacol. pmid:13969408
GUARNIERE I et al. [NODULAR PURPURA IN INFANTS. (PRESENTATION OF A CLINICAL CASE AND COLLECTIVE REVIEW ON THE SUBJECT)]. 1963 Clin Pediatr (Bologna) pmid:14107111
OMORI A [ANTIHEMOPHILIC GLOBULIN CONSUMPTION DURING BLOOD COAGULATION]. 1963 Nippon Naika Gakkai Zasshi pmid:14156201
O'REILLY RA et al. STUDIES ON THE COUMARIN ANTICOAGULANT DRUGS: THE PHARMACODYNAMICS OF WARFARIN IN MAN. 1963 J. Clin. Invest. pmid:14074349
MAKI M and TAKANO A A CASE OF MENORRHAGE COMBINED WITH HYPOFIBRINOGENEMIA. 1963 Tohoku J. Exp. Med. pmid:14077062
SOARESFILHO A and BOCIKS J [PROGESTATIONAL HORMONES AND OTHER COMPOUNDS IN THE TREATMENT OF ABORTION. COMPARATIVE STUDY]. 1963 Minerva Ginecol pmid:14086252
BEYER RE The effect of ultraviolet light on mitochondria. VII. Restoration of dinitrophenol-activated adenosinetri-phosphatase by vitamin K following inhibition by farultraviolet light. 1963 Can J Biochem Physiol pmid:13967934
KWAPIS BW Anticoagulant therapy and dental practice. 1963 J Am Dent Assoc pmid:13927749