phylloquinone

Phylloquinone is a lipid of Prenol Lipids (PR) class. Phylloquinone is associated with abnormalities such as Vitamin K Deficiency, Malnutrition, Consumption-archaic term for TB, Osteoporosis and Hyperostosis, Diffuse Idiopathic Skeletal. The involved functions are known as Ingestion, Blood Circulation, Genetic Polymorphism, Intestinal Absorption and Process. Phylloquinone often locates in Blood, Body tissue, Hepatic, Membrane and Entire bony skeleton. The associated genes with phylloquinone are Vitamin K Epoxide Reductase Complex, Subunit 1, GGCX gene, CYP4F2 gene, Alleles and APOE gene. The related lipids are Micelles, 208-G, Fatty Acids, Total cholesterol and Sphingolipids. The related experimental models are Knock-out.

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Introduction

To understand associated biological information of phylloquinone, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with phylloquinone?

phylloquinone is suspected in Vitamin K Deficiency, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes, vitamin depletion, Malnutrition, Osteoporosis and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with phylloquinone

MeSH term MeSH ID Detail
Exanthema D005076 11 associated lipids
Thromboembolism D013923 6 associated lipids
Vitamin K Deficiency D014813 5 associated lipids
Total 3

PubChem Associated disorders and diseases

What pathways are associated with phylloquinone

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with phylloquinone?

Related references are published most in these journals:

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What functions are associated with phylloquinone?


Related references are published most in these journals:

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What lipids are associated with phylloquinone?

Related references are published most in these journals:

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What genes are associated with phylloquinone?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with phylloquinone?

Knock-out

Knock-out are used in the study 'A dedicated thioesterase of the Hotdog-fold family is required for the biosynthesis of the naphthoquinone ring of vitamin K1.' (Widhalm JR et al., 2009) and Knock-out are used in the study 'Deficiency in phylloquinone (vitamin K1) methylation affects prenyl quinone distribution, photosystem I abundance, and anthocyanin accumulation in the Arabidopsis AtmenG mutant.' (Lohmann A et al., 2006).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with phylloquinone

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Authors Title Published Journal PubMed Link
Greer FR Are breast-fed infants vitamin K deficient? 2001 Adv. Exp. Med. Biol. pmid:11787707
Onaga IC and Oyenuga KO Quantitative effects of interacting variables on vitamin K1, phylloquinone, entrapment in liposomes. 2001 Afr J Med Med Sci pmid:14510120
Green B et al. Phytomenadione or menadiol in the management of an elevated international normalized ratio (prothrombin time). 2000 Aliment. Pharmacol. Ther. pmid:11121919
Kidd PM Vitamins D and K as pleiotropic nutrients: clinical importance to the skeletal and cardiovascular systems and preliminary evidence for synergy. 2010 Altern Med Rev pmid:21155624
Lamson DW and Plaza SM The anticancer effects of vitamin K. 2003 Altern Med Rev pmid:12946240
Chao MT et al. An innovative acupuncture treatment for primary dysmenorrhea: a randomized, crossover pilot study. 2014 Jan-Feb Altern Ther Health Med pmid:24445356
Hollander D et al. Diurnal rhythmicity of absorption of a lipid compound (vitamin K-1) in vivo in the rat. 1978 Am J Dig Dis pmid:569972
DOUVRES PA EFFECT OF HIGH PARENTERAL DOSES OF VITAMIN-K ANALOGS AND SERUM ALBUMIN ON THE PROTHROMBIN LEVEL AND LIVER FUNCTION IN ALCOHOLIC CIRRHOSIS. 1965 Am J Dig Dis pmid:14331939
Byrd DC et al. Subcutaneous phytonadione for reversal of warfarin-induced elevation of the International Normalized Ratio. 1999 Am J Health Syst Pharm pmid:10582823
Bui L et al. Skin reaction to subcutaneous phytonadione injections. 2004 Am J Health Syst Pharm pmid:15011773