phylloquinone

Phylloquinone is a lipid of Prenol Lipids (PR) class. Phylloquinone is associated with abnormalities such as Vitamin K Deficiency, Malnutrition, Consumption-archaic term for TB, Osteoporosis and Hyperostosis, Diffuse Idiopathic Skeletal. The involved functions are known as Ingestion, Blood Circulation, Genetic Polymorphism, Intestinal Absorption and Process. Phylloquinone often locates in Blood, Body tissue, Hepatic, Membrane and Entire bony skeleton. The associated genes with phylloquinone are Vitamin K Epoxide Reductase Complex, Subunit 1, GGCX gene, CYP4F2 gene, Alleles and APOE gene. The related lipids are Micelles, 208-G, Fatty Acids, Total cholesterol and Sphingolipids. The related experimental models are Knock-out.

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Introduction

To understand associated biological information of phylloquinone, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with phylloquinone?

phylloquinone is suspected in Vitamin K Deficiency, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes, vitamin depletion, Malnutrition, Osteoporosis and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with phylloquinone

MeSH term MeSH ID Detail
Exanthema D005076 11 associated lipids
Thromboembolism D013923 6 associated lipids
Vitamin K Deficiency D014813 5 associated lipids
Total 3

PubChem Associated disorders and diseases

What pathways are associated with phylloquinone

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with phylloquinone?

Related references are published most in these journals:

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What functions are associated with phylloquinone?


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What lipids are associated with phylloquinone?

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What genes are associated with phylloquinone?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with phylloquinone?

Knock-out

Knock-out are used in the study 'A dedicated thioesterase of the Hotdog-fold family is required for the biosynthesis of the naphthoquinone ring of vitamin K1.' (Widhalm JR et al., 2009) and Knock-out are used in the study 'Deficiency in phylloquinone (vitamin K1) methylation affects prenyl quinone distribution, photosystem I abundance, and anthocyanin accumulation in the Arabidopsis AtmenG mutant.' (Lohmann A et al., 2006).

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NCBI Entrez Crosslinks

All references with phylloquinone

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Authors Title Published Journal PubMed Link
Nusbaum-Cassuto E and Villoutreix J [Influence of ubiquinone on carotenogenesis in yeasts of the genus Rhodotorula]. 1967 Bull. Soc. Chim. Biol. pmid:6069845
Finney LA and Gholston D Cerebral aneurysm rupture during anticoagulant therapy with survival. 1967 JAMA pmid:6071662
Threlfall DR and Goodwin TW Nature, intracellular distribution and formation of terpenoid quinones in Euglena gracilis. 1967 Biochem. J. pmid:5340369
Hata Y [Vitamin K in obstetrics--effects of vitamin K1 on threatened abortion and premature labor]. 1967 Nippon Sanka Fujinka Gakkai Zasshi pmid:5627227
Vetter W et al. [Gas chromatography and mass spectrometry investigations of phytylubiquinone Vitamin K1, and Vitamin K2]. 1967 Helv. Chim. Acta pmid:5590992
Griffiths WT et al. Nature, intracellular distribution and formation of terpenoid quinones in maize and barley shoots. 1967 Biochem. J. pmid:6032988
Darrell RW Endogenous Aspergillus uveitis following heart surgery. 1967 Arch. Ophthalmol. pmid:6040013
Allen CF et al. Identification of a plastoquinone and two naphthoquinones in Anacystis nidulans by NMR and mass spectroscopy. 1967 Biochem. Biophys. Res. Commun. pmid:6049353
Jones B Negative effects of vitamin K preparations on glucuronyl transferase activity. 1967 Pediatrics pmid:6074140
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Spector I and Corn M Laboratory tests of hemostasis. The relation to hemorrhage in liver disease. 1967 Arch. Intern. Med. pmid:5298058
Hoppe W [The importance of the treatment with marcumar in oral surgery]. 1967 Zahnarztl Prax pmid:5298417
Gutnick DL et al. Cis-trans isomerism in naphthoquinones: interconversion and participation in oxidative phosphorylation. 1967 Science pmid:4293760
Görög P and Kovács IB Effects of vitamins K1 and K3 on adenosine nucleotide content of rat tissues. 1967 Mol. Pharmacol. pmid:6052711
Taylor PJ Hemorrhage while on anticoagulant therapy precipitated by drug interaction. 1967 Ariz Med pmid:6056202
Forattini C and Pulliero G [Experimental clinical research on the therapeutic action of AM 65234]. 1966 Clin Ter pmid:5990473
Di Mari SJ et al. Mass spectra of naphthoquinones. Vitamin K1(20). 1966 J. Am. Chem. Soc. pmid:5910960
Lapidot A and Cohen JS Reduction studies with naturally occurring quinones and their phosphate derivatives with reference to oxidative phosphorylation. 1966 J. Biol. Chem. pmid:5920811
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Watanabe T and Brodie AF Enzymatic formation of a phosphorylated derivative of vitamin K. 1966 Proc. Natl. Acad. Sci. U.S.A. pmid:5230188
McIntyre H Management, during dental surgery, of patients on anticoagulants. 1966 Lancet pmid:4161034
Martius C [Antagonists of the K-vitamins]. 1966 Bibl Nutr Dieta pmid:4161999
Barnhart MI Prothrombin synthesis: an example of hepatic function. 1965 Nov-Dec J. Histochem. Cytochem. pmid:4956116
Millar GJ et al. Antagonistic and antidotal action of vitamins K1 and K3 versus dicumarol in dogs. 1965 Aug-Sep Proc. Soc. Exp. Biol. Med. pmid:4158157
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Griminger P Vitamin K activity in chickens: phylloquinone and menadione in the presence of stress agents. 1965 J. Nutr. pmid:5859260
Sotomatsu M et al. [Combined use of vitamin K1 and adrenal cortex hormones in skin diseases]. 1965 Hifuka Kiyo pmid:5894589
Udall JA Human sources and absorption of vitamin K in relation to anticoagulation stability. 1965 JAMA pmid:5897315
Kaneoka T and Ogawa E [Implication of the routine administration of phytonadione in hemorrhagic disease of the newborn]. 1965 Sanfujinka No Jissai pmid:5899489
Mayer GA A rare complication of coumarin-congener anticoagulant therapy. 1965 Can Med Assoc J pmid:5890639
BELDING HH USE OF ANTICOAGULANTS IN THE PREVENTION OF VENOUS THROMBOEMBOLIC DISEASE IN POSTOPERATIVE PATIENTS. 1965 Arch Surg pmid:14267658
Terahata K and Takahashi A [The fine structure of liver cells observed after administration of vitamin K 1]. 1965 Iryo pmid:5834547
Gutnick DL and Brodie AF Phosphate-dependent incorporation of tritium into a naphthoquinone during oxidative phosphorylation. 1965 J. Biol. Chem. pmid:5835950
Jackman LM et al. [On the chemistry of vitamin K. 2. Total synthesis and stereochemistry of trans- and cis-(7'R,11'R)-phylloquinone and related compounds]. 1965 Helv. Chim. Acta pmid:5846757
Mamont P et al. [Quinones in oxidative phosphorylation. II. Acid dimerization of K vitamins]. 1965 Bull Soc Chim Fr pmid:5848684
Chen LH and Dallam RD Effect of quinones on mitochondrial phosphorylation, Pi-ATP exchange, and ATPase activities. II. Vitamin K-2 homologues and K-1 derivatives. 1965 Arch. Biochem. Biophys. pmid:4221488
SAIDI P et al. TRANSPLACENTAL TRANSFER OF BISHYDROXYCOUMARIN IN THE HUMAN. 1965 JAMA pmid:14245526
CHANDRASEKHAR N et al. THE EFFECT OF DICUMAROL ON PROTHROMBIN TIME IN RATS AND ITS RELATION TO VITAMIN K CONTENT OF LIVER. 1965 Can. J. Physiol. Pharmacol. pmid:14329349
DOUVRES PA EFFECT OF HIGH PARENTERAL DOSES OF VITAMIN-K ANALOGS AND SERUM ALBUMIN ON THE PROTHROMBIN LEVEL AND LIVER FUNCTION IN ALCOHOLIC CIRRHOSIS. 1965 Am J Dig Dis pmid:14331939
HENNINGER MD et al. COMPARATIVE STUDIES ON PLASTOQUINONES. I. EVIDENCE FOR THREE QUINONES IN THE BLUE-GREEN ALGA, ANACYSTIS NIDULANS. 1965 Arch. Biochem. Biophys. pmid:14321864
IBAYASHI H et al. ANTIGRANULOMATOUS ACTIVITY OF VITAMIN K1 AND ITS SUMMATION WITH THAT OF PREDNISOLONE. 1965 Endocrinology pmid:14289203
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