| MeSH term | MeSH ID | Detail |
|---|---|---|
| Exanthema | D005076 | 11 associated lipids |
| Thromboembolism | D013923 | 6 associated lipids |
| Vitamin K Deficiency | D014813 | 5 associated lipids |
Total
3
phylloquinone
Phylloquinone is a lipid of Prenol Lipids (PR) class. Phylloquinone is associated with abnormalities such as Vitamin K Deficiency, Malnutrition, Consumption-archaic term for TB, Osteoporosis and Hyperostosis, Diffuse Idiopathic Skeletal. The involved functions are known as Ingestion, Blood Circulation, Genetic Polymorphism, Intestinal Absorption and Process. Phylloquinone often locates in Blood, Body tissue, Hepatic, Membrane and Entire bony skeleton. The associated genes with phylloquinone are Vitamin K Epoxide Reductase Complex, Subunit 1, GGCX gene, CYP4F2 gene, Alleles and APOE gene. The related lipids are Micelles, 208-G, Fatty Acids, Total cholesterol and Sphingolipids. The related experimental models are Knock-out.
Cross Reference
Introduction
To understand associated biological information of phylloquinone, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with phylloquinone?
phylloquinone is suspected in Vitamin K Deficiency, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes, vitamin depletion, Malnutrition, Osteoporosis and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with phylloquinone
PubChem Associated disorders and diseases
What pathways are associated with phylloquinone
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with phylloquinone?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with phylloquinone?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with phylloquinone?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with phylloquinone?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with phylloquinone?
Knock-out
Knock-out are used in the study 'A dedicated thioesterase of the Hotdog-fold family is required for the biosynthesis of the naphthoquinone ring of vitamin K1.' (Widhalm JR et al., 2009) and Knock-out are used in the study 'Deficiency in phylloquinone (vitamin K1) methylation affects prenyl quinone distribution, photosystem I abundance, and anthocyanin accumulation in the Arabidopsis AtmenG mutant.' (Lohmann A et al., 2006).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
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NCBI Entrez Crosslinks
All references with phylloquinone
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Dowd P et al. | Vitamin K and energy transduction: a base strength amplification mechanism. | 1995 | Science | pmid:7569894 |
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| Groenen-van Dooren MM et al. | Bioavailability of phylloquinone and menaquinones after oral and colorectal administration in vitamin K-deficient rats. | 1995 | Biochem. Pharmacol. | pmid:7575640 |
| Sakamoto N et al. | Changes of K vitamins in portal and femoral venous plasma of rats after oral administration of phylloquinone and menaquinone-4. | 1995 | Int J Vitam Nutr Res | pmid:7591528 |
| Feuerbach D et al. | Mycotrienins. A new class of potent inhibitors of osteoclastic bone resorption. | 1995 | J. Biol. Chem. | pmid:7592784 |
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| Booth SL et al. | Tea and coffee brews are not dietary sources of vitamin K-1 (phylloquinone). | 1995 | J Am Diet Assoc | pmid:7798585 |
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| Breton J et al. | The binding sites of quinones in photosynthetic bacterial reaction centers investigated by light-induced FTIR difference spectroscopy: assignment of the QA vibrations in Rhodobacter sphaeroides using 18O- or 13C-labeled ubiquinone and vitamin K1. | 1994 | Biochemistry | pmid:8161557 |
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| Hodges SJ et al. | Detection and measurement of vitamins K1 and K2 in human cortical and trabecular bone. | 1993 | J. Bone Miner. Res. | pmid:8213250 |
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| Chung JH et al. | Effects of vitamin K1 and menadione on ethanol metabolism and toxicity. | 1993 | Drug Chem Toxicol | pmid:8281891 |
| Pengo V et al. | Reversal of excessive effect of regular anticoagulation: low oral dose of phytonadione (vitamin K1) compared with warfarin discontinuation. | 1993 | Blood Coagul. Fibrinolysis | pmid:8292723 |
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| Schubiger G et al. | Vitamin K1 concentration in breast-fed neonates after oral or intramuscular administration of a single dose of a new mixed-micellar preparation of phylloquinone. | 1993 | J. Pediatr. Gastroenterol. Nutr. | pmid:8315554 |
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| Groenen-van Dooren MM et al. | The relative effects of phylloquinone and menaquinone-4 on the blood coagulation factor synthesis in vitamin K-deficient rats. | 1993 | Biochem. Pharmacol. | pmid:8347166 |
| Sétif P and Brettel K | Forward electron transfer from phylloquinone A1 to iron-sulfur centers in spinach photosystem I. | 1993 | Biochemistry | pmid:8347589 |
| Tokumura T et al. | Evaluation of bioavailability upon oral administration of phytonadione preparations in beagle dogs. | 1993 | Biol. Pharm. Bull. | pmid:8364482 |
| Cornelissen EA et al. | Prevention of vitamin K deficiency in infancy by weekly administration of vitamin K. | 1993 | Acta Paediatr. | pmid:8374213 |
| Sieckmann I et al. | Transient electron paramagnetic resonance of the triplet state of P700 in photosystem I: evidence for triplet delocalization at room temperature. | 1993 | Biochemistry | pmid:8387818 |
| Saupe J et al. | Phylloquinone transport and its influence on gamma-carboxyglutamate residues of osteocalcin in patients on maintenance hemodialysis. | 1993 | Am. J. Clin. Nutr. | pmid:8393269 |
| Bovill EG et al. | Vitamin K1 metabolism and the production of des-carboxy prothrombin and protein C in the term and premature neonate. | 1993 | Blood | pmid:8417804 |
| Anai T et al. | Can prenatal vitamin K1 (phylloquinone) supplementation replace prophylaxis at birth? | 1993 | Obstet Gynecol | pmid:8423960 |