MeSH term | MeSH ID | Detail |
---|---|---|
Exanthema | D005076 | 11 associated lipids |
Thromboembolism | D013923 | 6 associated lipids |
Vitamin K Deficiency | D014813 | 5 associated lipids |
Phylloquinone is a lipid of Prenol Lipids (PR) class. Phylloquinone is associated with abnormalities such as Vitamin K Deficiency, Malnutrition, Consumption-archaic term for TB, Osteoporosis and Hyperostosis, Diffuse Idiopathic Skeletal. The involved functions are known as Ingestion, Blood Circulation, Genetic Polymorphism, Intestinal Absorption and Process. Phylloquinone often locates in Blood, Body tissue, Hepatic, Membrane and Entire bony skeleton. The associated genes with phylloquinone are Vitamin K Epoxide Reductase Complex, Subunit 1, GGCX gene, CYP4F2 gene, Alleles and APOE gene. The related lipids are Micelles, 208-G, Fatty Acids, Total cholesterol and Sphingolipids. The related experimental models are Knock-out.
To understand associated biological information of phylloquinone, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
phylloquinone is suspected in Vitamin K Deficiency, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes, vitamin depletion, Malnutrition, Osteoporosis and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with phylloquinone
MeSH term | MeSH ID | Detail |
---|---|---|
Exanthema | D005076 | 11 associated lipids |
Thromboembolism | D013923 | 6 associated lipids |
Vitamin K Deficiency | D014813 | 5 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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Knock-out are used in the study 'A dedicated thioesterase of the Hotdog-fold family is required for the biosynthesis of the naphthoquinone ring of vitamin K1.' (Widhalm JR et al., 2009) and Knock-out are used in the study 'Deficiency in phylloquinone (vitamin K1) methylation affects prenyl quinone distribution, photosystem I abundance, and anthocyanin accumulation in the Arabidopsis AtmenG mutant.' (Lohmann A et al., 2006).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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BEAMISH RE and STORRIE VM | Severe haemolytic reaction following the intravenous administration of emulsified vitamin K (mephyton). | 1956 | Can Med Assoc J | pmid:13284670 |
DAWSON P | Effect of intravenous vitamin K1 on the action of phenindione. | 1955 | Br Med J | pmid:13269887 |
ENGLISH A et al. | Vitamin K1 in the control of phenylindanedione-induced anticoagulant therapy. | 1955 | Can Med Assoc J | pmid:13231011 |
CHALMERS JN et al. | Antagonistic effect of oral vitamin K1 on the action of ethyl biscoumacetate and phenylindanedione. | 1954 | Br Med J | pmid:13199354 |
GUTTAS CG et al. | Studies on the anticoagulant phenylindanedione. I. The effect of emulsified vitamin K1 on phenylindanedione-induced hypoprothrombinemia. | 1953 | Blood | pmid:13032197 |
REID RA | The treatment of hypoprothrombinemia with orally administered vitamin K 1. | 1951 | Q Bull Northwest Univ Med Sch | pmid:14864841 |
Bidlack M et al. | Determination of Vitamin K1 in Infant, Pediatric, and Adult Nutritionals by HPLC with Fluorescence Detection: Single-Laboratory Validation, First Action 2015.09. | J AOAC Int | pmid:26525258 | |
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