MeSH term | MeSH ID | Detail |
---|---|---|
Exanthema | D005076 | 11 associated lipids |
Thromboembolism | D013923 | 6 associated lipids |
Vitamin K Deficiency | D014813 | 5 associated lipids |
Phylloquinone is a lipid of Prenol Lipids (PR) class. Phylloquinone is associated with abnormalities such as Vitamin K Deficiency, Malnutrition, Consumption-archaic term for TB, Osteoporosis and Hyperostosis, Diffuse Idiopathic Skeletal. The involved functions are known as Ingestion, Blood Circulation, Genetic Polymorphism, Intestinal Absorption and Process. Phylloquinone often locates in Blood, Body tissue, Hepatic, Membrane and Entire bony skeleton. The associated genes with phylloquinone are Vitamin K Epoxide Reductase Complex, Subunit 1, GGCX gene, CYP4F2 gene, Alleles and APOE gene. The related lipids are Micelles, 208-G, Fatty Acids, Total cholesterol and Sphingolipids. The related experimental models are Knock-out.
To understand associated biological information of phylloquinone, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
phylloquinone is suspected in Vitamin K Deficiency, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes, vitamin depletion, Malnutrition, Osteoporosis and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with phylloquinone
MeSH term | MeSH ID | Detail |
---|---|---|
Exanthema | D005076 | 11 associated lipids |
Thromboembolism | D013923 | 6 associated lipids |
Vitamin K Deficiency | D014813 | 5 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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Knock-out are used in the study 'A dedicated thioesterase of the Hotdog-fold family is required for the biosynthesis of the naphthoquinone ring of vitamin K1.' (Widhalm JR et al., 2009) and Knock-out are used in the study 'Deficiency in phylloquinone (vitamin K1) methylation affects prenyl quinone distribution, photosystem I abundance, and anthocyanin accumulation in the Arabidopsis AtmenG mutant.' (Lohmann A et al., 2006).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Rybnikov VN et al. | [Naphthoquinones as immunomodulators during intensive exertion]. | 1997 | Antibiot. Khimioter. | pmid:9265467 |
Ronden JE et al. | Modulation of arterial thrombosis tendency in rats by vitamin K and its side chains. | 1997 | Atherosclerosis | pmid:9247360 |
Indyk HE and Woollard DC | Vitamin K in milk and infant formulas: determination and distribution of phylloquinone and menaquinone-4. | 1997 | Analyst | pmid:9246814 |
Zech SG et al. | Measurement of cofactor distances between P700.+ and A1.- in native and quinone-substituted photosystem I using pulsed electron paramagnetic resonance spectroscopy. | 1997 | Biochemistry | pmid:9245409 |
Schlagheck TG et al. | Olestra's effect on vitamins D and E in humans can be offset by increasing dietary levels of these vitamins. | 1997 | J. Nutr. | pmid:9237962 |
Schlagheck TG et al. | Olestra dose response on fat-soluble and water-soluble nutrients in humans. | 1997 | J. Nutr. | pmid:9237961 |
Israels LG et al. | The riddle of vitamin K1 deficit in the newborn. | 1997 | Semin. Perinatol. | pmid:9190038 |
Beker LT et al. | Effect of vitamin K1 supplementation on vitamin K status in cystic fibrosis patients. | 1997 | J. Pediatr. Gastroenterol. Nutr. | pmid:9161943 |
Yamamoto R et al. | Menaquinone-4 accumulation in various tissues after an oral administration of phylloquinone in Wistar rats. | 1997 | J. Nutr. Sci. Vitaminol. | pmid:9151247 |
La Rosa FG et al. | Brodifacoum intoxication with marijuana smoking. | 1997 | Arch. Pathol. Lab. Med. | pmid:9111096 |