| MeSH term | MeSH ID | Detail |
|---|---|---|
| Exanthema | D005076 | 11 associated lipids |
| Thromboembolism | D013923 | 6 associated lipids |
| Vitamin K Deficiency | D014813 | 5 associated lipids |
Total
3
phylloquinone
Phylloquinone is a lipid of Prenol Lipids (PR) class. Phylloquinone is associated with abnormalities such as Vitamin K Deficiency, Malnutrition, Consumption-archaic term for TB, Osteoporosis and Hyperostosis, Diffuse Idiopathic Skeletal. The involved functions are known as Ingestion, Blood Circulation, Genetic Polymorphism, Intestinal Absorption and Process. Phylloquinone often locates in Blood, Body tissue, Hepatic, Membrane and Entire bony skeleton. The associated genes with phylloquinone are Vitamin K Epoxide Reductase Complex, Subunit 1, GGCX gene, CYP4F2 gene, Alleles and APOE gene. The related lipids are Micelles, 208-G, Fatty Acids, Total cholesterol and Sphingolipids. The related experimental models are Knock-out.
Cross Reference
Introduction
To understand associated biological information of phylloquinone, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with phylloquinone?
phylloquinone is suspected in Vitamin K Deficiency, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes, vitamin depletion, Malnutrition, Osteoporosis and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with phylloquinone
PubChem Associated disorders and diseases
What pathways are associated with phylloquinone
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with phylloquinone?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with phylloquinone?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with phylloquinone?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with phylloquinone?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with phylloquinone?
Knock-out
Knock-out are used in the study 'A dedicated thioesterase of the Hotdog-fold family is required for the biosynthesis of the naphthoquinone ring of vitamin K1.' (Widhalm JR et al., 2009) and Knock-out are used in the study 'Deficiency in phylloquinone (vitamin K1) methylation affects prenyl quinone distribution, photosystem I abundance, and anthocyanin accumulation in the Arabidopsis AtmenG mutant.' (Lohmann A et al., 2006).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
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NCBI Entrez Crosslinks
All references with phylloquinone
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Greer FR | Vitamin K in human milk--still not enough. | 2004 | Acta Paediatr. | pmid:15188967 |
| Kojima T et al. | Vitamin K concentrations in the maternal milk of Japanese women. | 2004 | Acta Paediatr. | pmid:15188971 |
| Clarke P et al. | Vitamin K status of preterm infants with a prolonged prothrombin time. | 2005 | Acta Paediatr. | pmid:16421045 |
| Hansen KN et al. | Weekly oral vitamin K prophylaxis in Denmark. | 2003 | Acta Paediatr. | pmid:12892158 |
| Puppi A and Dely M | Correlations between the actual redox-state potential (E0') of biophase and heart activity in vivo. | 1991 | Acta Physiol Hung | pmid:1950592 |
| Csaba G and Karabélyos CS | Influence of a single treatment with vitamin E or K (hormonal imprinting) of neonatal rats on the sexual behavior of adults. | 2000 | Acta Physiol Hung | pmid:11032045 |
| Gábor M and Rázga Z | The acenocoumarol-carrageenin test. | 1990 | Acta Physiol Hung | pmid:2075826 |
| Shea MK and Holden RM | Vitamin K status and vascular calcification: evidence from observational and clinical studies. | 2012 | Adv Nutr | pmid:22516723 |
| Shearer MJ et al. | Vitamin K nutrition, metabolism, and requirements: current concepts and future research. | 2012 | Adv Nutr | pmid:22516726 |
| Vermeer C and Ulrich MM | The effect of microgravity on plasma-osteocalcin. | 1986 | Adv Space Res | pmid:11537812 |
| Greer FR | Are breast-fed infants vitamin K deficient? | 2001 | Adv. Exp. Med. Biol. | pmid:11787707 |
| Onaga IC and Oyenuga KO | Quantitative effects of interacting variables on vitamin K1, phylloquinone, entrapment in liposomes. | 2001 | Afr J Med Med Sci | pmid:14510120 |
| Green B et al. | Phytomenadione or menadiol in the management of an elevated international normalized ratio (prothrombin time). | 2000 | Aliment. Pharmacol. Ther. | pmid:11121919 |
| Kidd PM | Vitamins D and K as pleiotropic nutrients: clinical importance to the skeletal and cardiovascular systems and preliminary evidence for synergy. | 2010 | Altern Med Rev | pmid:21155624 |
| Lamson DW and Plaza SM | The anticancer effects of vitamin K. | 2003 | Altern Med Rev | pmid:12946240 |
| Chao MT et al. | An innovative acupuncture treatment for primary dysmenorrhea: a randomized, crossover pilot study. | 2014 Jan-Feb | Altern Ther Health Med | pmid:24445356 |
| Hollander D et al. | Diurnal rhythmicity of absorption of a lipid compound (vitamin K-1) in vivo in the rat. | 1978 | Am J Dig Dis | pmid:569972 |
| DOUVRES PA | EFFECT OF HIGH PARENTERAL DOSES OF VITAMIN-K ANALOGS AND SERUM ALBUMIN ON THE PROTHROMBIN LEVEL AND LIVER FUNCTION IN ALCOHOLIC CIRRHOSIS. | 1965 | Am J Dig Dis | pmid:14331939 |
| Byrd DC et al. | Subcutaneous phytonadione for reversal of warfarin-induced elevation of the International Normalized Ratio. | 1999 | Am J Health Syst Pharm | pmid:10582823 |
| Bui L et al. | Skin reaction to subcutaneous phytonadione injections. | 2004 | Am J Health Syst Pharm | pmid:15011773 |