| MeSH term | MeSH ID | Detail |
|---|---|---|
| Exanthema | D005076 | 11 associated lipids |
| Thromboembolism | D013923 | 6 associated lipids |
| Vitamin K Deficiency | D014813 | 5 associated lipids |
Total
3
phylloquinone
Phylloquinone is a lipid of Prenol Lipids (PR) class. Phylloquinone is associated with abnormalities such as Vitamin K Deficiency, Malnutrition, Consumption-archaic term for TB, Osteoporosis and Hyperostosis, Diffuse Idiopathic Skeletal. The involved functions are known as Ingestion, Blood Circulation, Genetic Polymorphism, Intestinal Absorption and Process. Phylloquinone often locates in Blood, Body tissue, Hepatic, Membrane and Entire bony skeleton. The associated genes with phylloquinone are Vitamin K Epoxide Reductase Complex, Subunit 1, GGCX gene, CYP4F2 gene, Alleles and APOE gene. The related lipids are Micelles, 208-G, Fatty Acids, Total cholesterol and Sphingolipids. The related experimental models are Knock-out.
Cross Reference
Introduction
To understand associated biological information of phylloquinone, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with phylloquinone?
phylloquinone is suspected in Vitamin K Deficiency, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes, vitamin depletion, Malnutrition, Osteoporosis and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with phylloquinone
PubChem Associated disorders and diseases
What pathways are associated with phylloquinone
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with phylloquinone?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with phylloquinone?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with phylloquinone?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What genes are associated with phylloquinone?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with phylloquinone?
Knock-out
Knock-out are used in the study 'A dedicated thioesterase of the Hotdog-fold family is required for the biosynthesis of the naphthoquinone ring of vitamin K1.' (Widhalm JR et al., 2009) and Knock-out are used in the study 'Deficiency in phylloquinone (vitamin K1) methylation affects prenyl quinone distribution, photosystem I abundance, and anthocyanin accumulation in the Arabidopsis AtmenG mutant.' (Lohmann A et al., 2006).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
NCBI Entrez Crosslinks
All references with phylloquinone
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Fackir L et al. | Pulse radiolysis study of vitamin K1 reduction in ethanolic solution. | 1995 | Radiat. Res. | pmid:7997519 |
| REID RA | The treatment of hypoprothrombinemia with orally administered vitamin K 1. | 1951 | Q Bull Northwest Univ Med Sch | pmid:14864841 |
| Prynne CJ et al. | Intake and sources of phylloquinone (vitamin K(1)) in 4-year-old British children: comparison between 1950 and the 1990s. | 2005 | Public Health Nutr | pmid:15877910 |
| Hindersin P et al. | [Coagulation physiological controls in subarachnoid hemorrhages and their therapeutic implications]. | 1982 | Psychiatr Neurol Med Psychol (Leipz) | pmid:7100333 |
| Conly JM and Stein K | The production of menaquinones (vitamin K2) by intestinal bacteria and their role in maintaining coagulation homeostasis. | 1992 Oct-Dec | Prog Food Nutr Sci | pmid:1492156 |
| Marshall FN | Potency and coagulation factor effects of 2,3,5,6-tetrachloro-4-pyridinol compared to warfarin and its antagonism by vitamin K. | 1972 | Proc. Soc. Exp. Biol. Med. | pmid:5023769 |
| Yen CS and Mack DO | Solubilized rat liver vitamin K carboxylase demonstrates little selectivity between vitamin K1 and the menaquinones. | 1980 | Proc. Soc. Exp. Biol. Med. | pmid:7443718 |
| ROBINSON HJ et al. | EFFECT OF CHOLESTYRAMINE, A BILE ACID BINDING POLYMER, ON VITAMIN K1 ABSORPTION IN DOGS. | 1964 | Proc. Soc. Exp. Biol. Med. | pmid:14117411 |
| Millar GJ et al. | Antagonistic and antidotal action of vitamins K1 and K3 versus dicumarol in dogs. | 1965 Aug-Sep | Proc. Soc. Exp. Biol. Med. | pmid:4158157 |
| Barkhan P and Shearer MJ | Metabolism of vitamin K1 (phylloquinone) in man. | 1977 | Proc. R. Soc. Med. | pmid:859820 |
| Eugeni Piller L et al. | Chloroplast lipid droplet type II NAD(P)H quinone oxidoreductase is essential for prenylquinone metabolism and vitamin K1 accumulation. | 2011 | Proc. Natl. Acad. Sci. U.S.A. | pmid:21844348 |
| Li Y et al. | Directing electron transfer within Photosystem I by breaking H-bonds in the cofactor branches. | 2006 | Proc. Natl. Acad. Sci. U.S.A. | pmid:16467143 |
| Mukharji I and Silverman RB | Purification of a vitamin K epoxide reductase that catalyzes conversion of vitamin K 2,3-epoxide to 3-hydroxy-2-methyl-3-phytyl-2,3-dihydronaphthoquinone. | 1985 | Proc. Natl. Acad. Sci. U.S.A. | pmid:3857611 |
| Chu PH et al. | Purified vitamin K epoxide reductase alone is sufficient for conversion of vitamin K epoxide to vitamin K and vitamin K to vitamin KH2. | 2006 | Proc. Natl. Acad. Sci. U.S.A. | pmid:17164330 |
| Watanabe T and Brodie AF | Enzymatic formation of a phosphorylated derivative of vitamin K. | 1966 | Proc. Natl. Acad. Sci. U.S.A. | pmid:5230188 |
| Widhalm JR et al. | A dedicated thioesterase of the Hotdog-fold family is required for the biosynthesis of the naphthoquinone ring of vitamin K1. | 2009 | Proc. Natl. Acad. Sci. U.S.A. | pmid:19321747 |
| Haroon Y et al. | Assay of vitamin K1 (phylloquinone) by high performance liquid chromatography: values for human and cow's milk. | 1980 | Proc Nutr Soc | pmid:7403086 |
| Prevention of haemorrhagic disease of the newborn. Routine vitamin K1 administration is justified. | 1998 | Prescrire Int | pmid:10342952 | |
| Fluri S et al. | [Hemorrhage in vitamin K deficiency--a preventable entity]. | 2007 | Praxis (Bern 1994) | pmid:17506390 |
| Jin S et al. | Effect of dietary vitamin K1 on selected plasma characteristics and bone ash in young turkeys fed diets adequate or deficient in vitamin D3. | 2001 | Poult. Sci. | pmid:11372710 |