phylloquinone

Phylloquinone is a lipid of Prenol Lipids (PR) class. Phylloquinone is associated with abnormalities such as Vitamin K Deficiency, Malnutrition, Consumption-archaic term for TB, Osteoporosis and Hyperostosis, Diffuse Idiopathic Skeletal. The involved functions are known as Ingestion, Blood Circulation, Genetic Polymorphism, Intestinal Absorption and Process. Phylloquinone often locates in Blood, Body tissue, Hepatic, Membrane and Entire bony skeleton. The associated genes with phylloquinone are Vitamin K Epoxide Reductase Complex, Subunit 1, GGCX gene, CYP4F2 gene, Alleles and APOE gene. The related lipids are Micelles, 208-G, Fatty Acids, Total cholesterol and Sphingolipids. The related experimental models are Knock-out.

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Introduction

To understand associated biological information of phylloquinone, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with phylloquinone?

phylloquinone is suspected in Vitamin K Deficiency, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes, vitamin depletion, Malnutrition, Osteoporosis and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with phylloquinone

MeSH term MeSH ID Detail
Exanthema D005076 11 associated lipids
Thromboembolism D013923 6 associated lipids
Vitamin K Deficiency D014813 5 associated lipids
Total 3

PubChem Associated disorders and diseases

What pathways are associated with phylloquinone

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with phylloquinone?

Related references are published most in these journals:

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What functions are associated with phylloquinone?


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What lipids are associated with phylloquinone?

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What genes are associated with phylloquinone?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with phylloquinone?

Knock-out

Knock-out are used in the study 'A dedicated thioesterase of the Hotdog-fold family is required for the biosynthesis of the naphthoquinone ring of vitamin K1.' (Widhalm JR et al., 2009) and Knock-out are used in the study 'Deficiency in phylloquinone (vitamin K1) methylation affects prenyl quinone distribution, photosystem I abundance, and anthocyanin accumulation in the Arabidopsis AtmenG mutant.' (Lohmann A et al., 2006).

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NCBI Entrez Crosslinks

All references with phylloquinone

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Authors Title Published Journal PubMed Link
Imanaka M et al. Identification of phylloquinone (vitamin K1) as an unknown peak in electron capture detection gas chromatograms of pyrethroid insecticide residues. 1996 Mar-Apr J AOAC Int pmid:8920143
Sundaram KS et al. Vitamin K status influences brain sulfatide metabolism in young mice and rats. 1996 J. Nutr. pmid:8914944
Stoeckel K et al. Elimination half-life of vitamin K1 in neonates is longer than is generally assumed: implications for the prophylaxis of haemorrhaghic disease of the newborn. 1996 Eur. J. Clin. Pharmacol. pmid:8866641
Shearer MJ et al. Effect of warfarin on the metabolism of phylloquinone (vitamin K1):dose-response relationships in man. 1977 Clin Sci Mol Med pmid:884934
Booth SL et al. Dihydro-vitamin K1: primary food sources and estimated dietary intakes in the American diet. 1996 Lipids pmid:8827694
Booth SL et al. Plasma concentrations of dihydro-vitamin K1 following dietary intake of a hydrogenated vitamin K1-rich vegetable oil. 1996 Lipids pmid:8827693
Loughnan PM et al. Late onset haemorrhagic disease in premature infants who received intravenous vitamin K1. 1996 J Paediatr Child Health pmid:8827551
Loughnan PM and McDougall PN Does intramuscular vitamin K1 act as an unintended depot preparation? 1996 J Paediatr Child Health pmid:8827545
Weathermon RA et al. Comment: oral vitamin K1 to reverse warfarin activity. 1996 Jul-Aug Ann Pharmacother pmid:8826584
Gijsbers BL et al. Effect of food composition on vitamin K absorption in human volunteers. 1996 Br. J. Nutr. pmid:8813897