phylloquinone

Phylloquinone is a lipid of Prenol Lipids (PR) class. Phylloquinone is associated with abnormalities such as Vitamin K Deficiency, Malnutrition, Consumption-archaic term for TB, Osteoporosis and Hyperostosis, Diffuse Idiopathic Skeletal. The involved functions are known as Ingestion, Blood Circulation, Genetic Polymorphism, Intestinal Absorption and Process. Phylloquinone often locates in Blood, Body tissue, Hepatic, Membrane and Entire bony skeleton. The associated genes with phylloquinone are Vitamin K Epoxide Reductase Complex, Subunit 1, GGCX gene, CYP4F2 gene, Alleles and APOE gene. The related lipids are Micelles, 208-G, Fatty Acids, Total cholesterol and Sphingolipids. The related experimental models are Knock-out.

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Introduction

To understand associated biological information of phylloquinone, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with phylloquinone?

phylloquinone is suspected in Vitamin K Deficiency, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes, vitamin depletion, Malnutrition, Osteoporosis and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with phylloquinone

MeSH term MeSH ID Detail
Exanthema D005076 11 associated lipids
Thromboembolism D013923 6 associated lipids
Vitamin K Deficiency D014813 5 associated lipids
Total 3

PubChem Associated disorders and diseases

What pathways are associated with phylloquinone

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with phylloquinone?

Related references are published most in these journals:

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What functions are associated with phylloquinone?


Related references are published most in these journals:

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What lipids are associated with phylloquinone?

Related references are published most in these journals:

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What genes are associated with phylloquinone?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with phylloquinone?

Knock-out

Knock-out are used in the study 'A dedicated thioesterase of the Hotdog-fold family is required for the biosynthesis of the naphthoquinone ring of vitamin K1.' (Widhalm JR et al., 2009) and Knock-out are used in the study 'Deficiency in phylloquinone (vitamin K1) methylation affects prenyl quinone distribution, photosystem I abundance, and anthocyanin accumulation in the Arabidopsis AtmenG mutant.' (Lohmann A et al., 2006).

Related references are published most in these journals:

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NCBI Entrez Crosslinks

All references with phylloquinone

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Authors Title Published Journal PubMed Link
Byrd DC et al. Subcutaneous phytonadione for reversal of warfarin-induced elevation of the International Normalized Ratio. 1999 Am J Health Syst Pharm pmid:10582823
Bui L et al. Skin reaction to subcutaneous phytonadione injections. 2004 Am J Health Syst Pharm pmid:15011773
Stork CM et al. Elevated International Normalized Ratio associated with long-term azithromycin therapy in a child with cerebral palsy. 2011 Am J Health Syst Pharm pmid:21593229
Lee R et al. Moxifloxacin-acetaminophen-warfarin interaction during bacille Calmette-Guerin treatment for bladder cancer. 2011 Am J Health Syst Pharm pmid:21515865
Nutescu EA New approaches to reversing oral anticoagulant therapy. Introduction. 2013 Am J Health Syst Pharm pmid:23640527
Kalus JS Pharmacologic interventions for reversing the effects of oral anticoagulants. 2013 Am J Health Syst Pharm pmid:23640528
Dager WE Developing a management plan for oral anticoagulant reversal. 2013 Am J Health Syst Pharm pmid:23640529
Sauberan JB et al. Origins of and solutions for neonatal medication-dispensing errors. 2010 Am J Health Syst Pharm pmid:20044369
Kutsop JJ Update on vitamin K1 content of enteral products. 1984 Am J Hosp Pharm pmid:6437219
Longe RL Letter: Stability of phytonadione in hyperalimentation fluids. 1974 Am J Hosp Pharm pmid:4215317