phylloquinone

Phylloquinone is a lipid of Prenol Lipids (PR) class. Phylloquinone is associated with abnormalities such as Vitamin K Deficiency, Malnutrition, Consumption-archaic term for TB, Osteoporosis and Hyperostosis, Diffuse Idiopathic Skeletal. The involved functions are known as Ingestion, Blood Circulation, Genetic Polymorphism, Intestinal Absorption and Process. Phylloquinone often locates in Blood, Body tissue, Hepatic, Membrane and Entire bony skeleton. The associated genes with phylloquinone are Vitamin K Epoxide Reductase Complex, Subunit 1, GGCX gene, CYP4F2 gene, Alleles and APOE gene. The related lipids are Micelles, 208-G, Fatty Acids, Total cholesterol and Sphingolipids. The related experimental models are Knock-out.

Cross Reference

Introduction

To understand associated biological information of phylloquinone, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with phylloquinone?

phylloquinone is suspected in Vitamin K Deficiency, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes, vitamin depletion, Malnutrition, Osteoporosis and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with phylloquinone

MeSH term MeSH ID Detail
Exanthema D005076 11 associated lipids
Thromboembolism D013923 6 associated lipids
Vitamin K Deficiency D014813 5 associated lipids
Total 3

PubChem Associated disorders and diseases

What pathways are associated with phylloquinone

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with phylloquinone?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with phylloquinone?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with phylloquinone?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What genes are associated with phylloquinone?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with phylloquinone?

Knock-out

Knock-out are used in the study 'A dedicated thioesterase of the Hotdog-fold family is required for the biosynthesis of the naphthoquinone ring of vitamin K1.' (Widhalm JR et al., 2009) and Knock-out are used in the study 'Deficiency in phylloquinone (vitamin K1) methylation affects prenyl quinone distribution, photosystem I abundance, and anthocyanin accumulation in the Arabidopsis AtmenG mutant.' (Lohmann A et al., 2006).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

NCBI Entrez Crosslinks

All references with phylloquinone

Download all related citations
Per page 10 20 50 100 | Total 1365
Authors Title Published Journal PubMed Link
Park BK et al. The dose-dependent effect of warfarin on vitamin K1 metabolism and clotting factor synthesis in the rabbit. 1980 Biochem. Pharmacol. pmid:7396990
Meeks RG and Couri D Inhibition by warfarin of prothrombin synthesis and of lipid-saccharide synthesis in rat liver. 1980 Biochim. Biophys. Acta pmid:7388053
Elliott GR et al. Assay procedure for the vitamin K1 2,3-epoxide-reducing system. 1980 Meth. Enzymol. pmid:7366422
Nakata H and Tsuchida E Determination of vitamin K1 in photodegradation products by gas-liquid chromatography. 1980 Meth. Enzymol. pmid:7366421
Robison JW and Odom RB Delayed cutaneous reaction to phytonadione. 1978 Arch Dermatol pmid:736587
Carter A et al. Multiple acquired haemostatic defects. Case report and review of the literature. 1980 Haemostasis pmid:7358321
Sherman PA and Sander EG Vitamin K epoxide reductase: evidence that vitamin K dihydroquinone is a product of vitamin K epoxide reduction. 1981 Biochem. Biophys. Res. Commun. pmid:7332587
Kolb E [Recent discoveries on the biochemical significance of vitamin K and some characteristics of vitamin K dependent proteins]. 1981 Z Gesamte Inn Med pmid:7331379
Takahashi O and Hiraga K Inhibition of phylloquinone epoxide-dependent carboxylation of microsomal proteins from rat liver by 2,6-di-tert-butyl-4-methylene-2,5-cyclohexadienone. 1981 Food Cosmet Toxicol pmid:7327471
Carlisle DM and Blaschke TF Vitamin K1, vitamin K1 epoxide and warfarin interrelationships in the dog. 1981 Biochem. Pharmacol. pmid:7317089