| MeSH term | MeSH ID | Detail |
|---|---|---|
| Thromboembolism | D013923 | 6 associated lipids |
| Vitamin K Deficiency | D014813 | 5 associated lipids |
| Exanthema | D005076 | 11 associated lipids |
Total
3
phylloquinone
Phylloquinone is a lipid of Prenol Lipids (PR) class. Phylloquinone is associated with abnormalities such as Vitamin K Deficiency, Malnutrition, Consumption-archaic term for TB, Osteoporosis and Hyperostosis, Diffuse Idiopathic Skeletal. The involved functions are known as Ingestion, Blood Circulation, Genetic Polymorphism, Intestinal Absorption and Process. Phylloquinone often locates in Blood, Body tissue, Hepatic, Membrane and Entire bony skeleton. The associated genes with phylloquinone are Vitamin K Epoxide Reductase Complex, Subunit 1, GGCX gene, CYP4F2 gene, Alleles and APOE gene. The related lipids are Micelles, 208-G, Fatty Acids, Total cholesterol and Sphingolipids. The related experimental models are Knock-out.
Cross Reference
Introduction
To understand associated biological information of phylloquinone, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with phylloquinone?
phylloquinone is suspected in Vitamin K Deficiency, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes, vitamin depletion, Malnutrition, Osteoporosis and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with phylloquinone
PubChem Associated disorders and diseases
What pathways are associated with phylloquinone
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with phylloquinone?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with phylloquinone?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with phylloquinone?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with phylloquinone?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with phylloquinone?
Knock-out
Knock-out are used in the study 'A dedicated thioesterase of the Hotdog-fold family is required for the biosynthesis of the naphthoquinone ring of vitamin K1.' (Widhalm JR et al., 2009) and Knock-out are used in the study 'Deficiency in phylloquinone (vitamin K1) methylation affects prenyl quinone distribution, photosystem I abundance, and anthocyanin accumulation in the Arabidopsis AtmenG mutant.' (Lohmann A et al., 2006).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
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NCBI Entrez Crosslinks
All references with phylloquinone
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Shearer MJ et al. | Absorption and excretion of an oral dose of tritiated vitamin K1 in man. | 1970 | Br. J. Haematol. | pmid:5491582 |
| Bell RG and Matschiner JT | Vitamin K activity of phylloquinone oxide. | 1970 | Arch. Biochem. Biophys. | pmid:5497142 |
| Jansson O | Photoinduced fluorescence of phylloquinone (vitamin K1) in solution. | 1970 | Acta Chem Scand | pmid:5507484 |
| Matschiner JT et al. | Isolation and characterization of a new metabolite of phylloquinone in the rat. | 1970 | Biochim. Biophys. Acta | pmid:5418726 |
| Cocks JR | Anticoagulants and the acute abdomen. | 1970 | Med. J. Aust. | pmid:5431749 |
| Kipfer RK and Olson RE | Reversal by vitamin K of cycloheximide inhibited biosynthesis of prothrombin in the isolated perfused rat liver. | 1970 | Biochem. Biophys. Res. Commun. | pmid:5437347 |
| Ranhotra GS and Johnson BC | Vitamin K and prothrombin formation. | 1970 | Life Sci. | pmid:5437499 |
| Rietz P et al. | [Menaquinones from human liver and sludge]. | 1970 | Int Z Vitaminforsch | pmid:5450996 |
| Thierry MJ et al. | Vitamin K and warfarin distribution and metabolism in the warfarin-resistant rat. | 1970 | Am. J. Physiol. | pmid:5459483 |
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| Kimura I et al. | [Multiple drug therapy of malignant tumor using fibroblast-suppresive agents as the basis]. | 1970 | Nippon Rinsho | pmid:5466668 |
| Bernacki RJ and Bosmann HB | Warfarin and vitamin K accelerate protein and glycoprotein synthesis in isolated rat liver mitochondria in vitro. | 1970 | Biochem. Biophys. Res. Commun. | pmid:5518179 |
| Crisler C et al. | Intestinal obstruction in patients receiving anticoagulants. | 1970 | Surg. Clin. North Am. | pmid:5469456 |
| Suttie JW | The effect of cycloheximide administration on vitamin K-stimulated prothrombin formation. | 1970 | Arch. Biochem. Biophys. | pmid:4395694 |
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| Bell RG and Matschiner JT | Synthesis and destruction of prothrombin in the rat. | 1969 | Arch. Biochem. Biophys. | pmid:5362918 |
| Lichtenthaler HK | Light-stimulated synthesis of plastid quinones and pigments in etiolated barley seedings. | 1969 | Biochim. Biophys. Acta | pmid:5791105 |
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| Lichtenthaler HK and Tevini M | [Effect of UV-rays on the lipoquinone-pigment composition of isolated spinach chloroplasts]. | 1969 | Z. Naturforsch. B | pmid:4390030 |
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| Di Mari SJ et al. | The role of the quinone in oxidative phosphorylation. Evidence against carbon-hydrogen bond cleavage. | 1968 | Biochemistry | pmid:5660055 |
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| DiMari SJ and Rapoport H | The reconstitution of oxidative phosphorylation in Mycobacterium phlei with cis- and trans-phylloquinone. Evidence against isomerization. | 1968 | Biochemistry | pmid:5660080 |
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| Dallam RD and Chen LH | Mechanism of oxidation and phosphorylation of naphthoquinol diphosphates. | 1968 | Arch. Biochem. Biophys. | pmid:4297041 |
| Nosoh Y et al. | Effect of menadione on the electron transport pathway of yeast mitochondria. | 1968 | Arch. Biochem. Biophys. | pmid:4300695 |
| Blomstrand R and Forsgren L | Vitamin K1-3H in man. Its intestinal absorption and transport in the thoracic duct lymph. | 1968 | Int Z Vitaminforsch | pmid:4302340 |
| Blomstrand R and Forsgren L | Labelled tocopherols in man. Intestinal absorption and thoracic-duct lymph transport of dl-alpha-tocopheryl-3,4-14C2 acetate dl-alpha-tocopheramine-3,4-14C2 dl-alpha-tocopherol-(5-methyl-3H) and N-(methyl-3H)-dl-gamma-tocopheramine. | 1968 | Int Z Vitaminforsch | pmid:4303536 |
| O'Reilly RA et al. | Hereditary resistance to coumarin anticoagulant drugs in man and rat. | 1968 | Ann. N. Y. Acad. Sci. | pmid:4189970 |
| Lakin KM and Sergeev LV | [Study of the effect of anticoagulants on the kidney function]. | 1967 Sep-Oct | Farmakol Toksikol | pmid:4175312 |
| Zanoio L et al. | [On the possibility of preventing the neonatal hypoprothrombinemic crisis by administration of vitamin K1 to the mother before labor]. | 1967 Jan-Feb | Attual Ostet Ginecol | pmid:5602278 |
| Gutnick DL et al. | Cis-trans isomerism in naphthoquinones: interconversion and participation in oxidative phosphorylation. | 1967 | Science | pmid:4293760 |