phylloquinone

Phylloquinone is a lipid of Prenol Lipids (PR) class. Phylloquinone is associated with abnormalities such as Vitamin K Deficiency, Malnutrition, Consumption-archaic term for TB, Osteoporosis and Hyperostosis, Diffuse Idiopathic Skeletal. The involved functions are known as Ingestion, Blood Circulation, Genetic Polymorphism, Intestinal Absorption and Process. Phylloquinone often locates in Blood, Body tissue, Hepatic, Membrane and Entire bony skeleton. The associated genes with phylloquinone are Vitamin K Epoxide Reductase Complex, Subunit 1, GGCX gene, CYP4F2 gene, Alleles and APOE gene. The related lipids are Micelles, 208-G, Fatty Acids, Total cholesterol and Sphingolipids. The related experimental models are Knock-out.

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Introduction

To understand associated biological information of phylloquinone, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with phylloquinone?

phylloquinone is suspected in Vitamin K Deficiency, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes, vitamin depletion, Malnutrition, Osteoporosis and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with phylloquinone

MeSH term MeSH ID Detail
Thromboembolism D013923 6 associated lipids
Vitamin K Deficiency D014813 5 associated lipids
Exanthema D005076 11 associated lipids
Total 3

PubChem Associated disorders and diseases

What pathways are associated with phylloquinone

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with phylloquinone?

Related references are published most in these journals:

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What functions are associated with phylloquinone?


Related references are published most in these journals:

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What lipids are associated with phylloquinone?

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What genes are associated with phylloquinone?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with phylloquinone?

Knock-out

Knock-out are used in the study 'A dedicated thioesterase of the Hotdog-fold family is required for the biosynthesis of the naphthoquinone ring of vitamin K1.' (Widhalm JR et al., 2009) and Knock-out are used in the study 'Deficiency in phylloquinone (vitamin K1) methylation affects prenyl quinone distribution, photosystem I abundance, and anthocyanin accumulation in the Arabidopsis AtmenG mutant.' (Lohmann A et al., 2006).

Related references are published most in these journals:

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NCBI Entrez Crosslinks

All references with phylloquinone

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Authors Title Published Journal PubMed Link
Roe DE et al. Multilaboratory comparison of growth characteristics for anaerobes, using 5 different agar media. 2002 Clin. Infect. Dis. pmid:12173106
Roe DE et al. Multilaboratory comparison of anaerobe susceptibility results using 3 different agar media. 2002 Clin. Infect. Dis. pmid:12173107
Cook KK et al. Measurement of cis and trans isomers of vitamin K1 in rat tissues by liquid chromatography with a C30 column. 2002 Jul-Aug J AOAC Int pmid:12180675
Booth SL et al. Phylloquinone absorption from phylloquinone-fortified oil is greater than from a vegetable in younger and older men and women. 2002 J. Nutr. pmid:12221218
Rigby SE et al. Photoaccumulation of the PsaB phyllosemiquinone in photosystem I of Chlamydomonas reinhardtii. 2002 Biochim. Biophys. Acta pmid:12351214
Fregin A et al. Homozygosity mapping of a second gene locus for hereditary combined deficiency of vitamin K-dependent clotting factors to the centromeric region of chromosome 16. 2002 Blood pmid:12384421
Riegert-Johnson DL and Volcheck GW The incidence of anaphylaxis following intravenous phytonadione (vitamin K1): a 5-year retrospective review. 2002 Ann. Allergy Asthma Immunol. pmid:12392385
Binkley NC et al. A high phylloquinone intake is required to achieve maximal osteocalcin gamma-carboxylation. 2002 Am. J. Clin. Nutr. pmid:12399278
Shimizu N et al. Shift of serum osteocalcin components between cord blood and blood at day 5 of life. 2002 Pediatr. Res. pmid:12409510
Lindquist J and Farroha SM Application of differential pulse polarography to the assay of vitamins. 1975 Analyst pmid:124542