phylloquinone

Phylloquinone is a lipid of Prenol Lipids (PR) class. Phylloquinone is associated with abnormalities such as Vitamin K Deficiency, Malnutrition, Consumption-archaic term for TB, Osteoporosis and Hyperostosis, Diffuse Idiopathic Skeletal. The involved functions are known as Ingestion, Blood Circulation, Genetic Polymorphism, Intestinal Absorption and Process. Phylloquinone often locates in Blood, Body tissue, Hepatic, Membrane and Entire bony skeleton. The associated genes with phylloquinone are Vitamin K Epoxide Reductase Complex, Subunit 1, GGCX gene, CYP4F2 gene, Alleles and APOE gene. The related lipids are Micelles, 208-G, Fatty Acids, Total cholesterol and Sphingolipids. The related experimental models are Knock-out.

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Introduction

To understand associated biological information of phylloquinone, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with phylloquinone?

phylloquinone is suspected in Vitamin K Deficiency, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes, vitamin depletion, Malnutrition, Osteoporosis and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with phylloquinone

MeSH term MeSH ID Detail
Thromboembolism D013923 6 associated lipids
Vitamin K Deficiency D014813 5 associated lipids
Exanthema D005076 11 associated lipids
Total 3

PubChem Associated disorders and diseases

What pathways are associated with phylloquinone

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with phylloquinone?

Related references are published most in these journals:

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What functions are associated with phylloquinone?


Related references are published most in these journals:

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What lipids are associated with phylloquinone?

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What genes are associated with phylloquinone?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with phylloquinone?

Knock-out

Knock-out are used in the study 'A dedicated thioesterase of the Hotdog-fold family is required for the biosynthesis of the naphthoquinone ring of vitamin K1.' (Widhalm JR et al., 2009) and Knock-out are used in the study 'Deficiency in phylloquinone (vitamin K1) methylation affects prenyl quinone distribution, photosystem I abundance, and anthocyanin accumulation in the Arabidopsis AtmenG mutant.' (Lohmann A et al., 2006).

Related references are published most in these journals:

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NCBI Entrez Crosslinks

All references with phylloquinone

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Authors Title Published Journal PubMed Link
Rawlinson A et al. Phylloquinone in gingival crevicular fluid in adult periodontitis. 1998 J. Clin. Periodontol. pmid:9722271
Paiva SA et al. Interaction between vitamin K nutriture and bacterial overgrowth in hypochlorhydria induced by omeprazole. 1998 Am. J. Clin. Nutr. pmid:9734750
Sato Y et al. Menatetrenone ameliorates osteopenia in disuse-affected limbs of vitamin D- and K-deficient stroke patients. 1998 Bone pmid:9737352
Balakrishnan G et al. Resonance Raman and infrared spectral studies on radical anions of model photosynthetic reaction center quinones (naphthoquinone derivatives). 1998 J. Biomol. Struct. Dyn. pmid:9745901
Bolisetty S et al. Vitamin K in preterm breastmilk with maternal supplementation. 1998 Acta Paediatr. pmid:9764891
Edenharder R et al. Effects of beta-carotene, retinal, riboflavin, alpha-tocopherol and vitamins C and K1 on sister-chromatid exchanges induced by 3-amino-1-methyl-5H-pyrido[4,3-b]indole (Trp-P-2) and cyclophosphamide in human lymphocyte cultures. 1998 Food Chem. Toxicol. pmid:9771550
Whitling AM et al. Comparing different routes and doses of phytonadione for reversing excessive anticoagulation. 1998 Arch. Intern. Med. pmid:9801181
James SB et al. Brodifacoum toxicity and treatment in a white-winged wood duck (Cairina scutulata). 1998 J. Zoo Wildl. Med. pmid:9809607
Hirsh J et al. Oral anticoagulants: mechanism of action, clinical effectiveness, and optimal therapeutic range. 1998 Chest pmid:9822057
Baltodano LE et al. Management of a patient with atrial fibrillation and factor VII deficiency. 1998 Ann Pharmacother pmid:9825099