| MeSH term | MeSH ID | Detail |
|---|---|---|
| Thromboembolism | D013923 | 6 associated lipids |
| Vitamin K Deficiency | D014813 | 5 associated lipids |
| Exanthema | D005076 | 11 associated lipids |
Total
3
phylloquinone
Phylloquinone is a lipid of Prenol Lipids (PR) class. Phylloquinone is associated with abnormalities such as Vitamin K Deficiency, Malnutrition, Consumption-archaic term for TB, Osteoporosis and Hyperostosis, Diffuse Idiopathic Skeletal. The involved functions are known as Ingestion, Blood Circulation, Genetic Polymorphism, Intestinal Absorption and Process. Phylloquinone often locates in Blood, Body tissue, Hepatic, Membrane and Entire bony skeleton. The associated genes with phylloquinone are Vitamin K Epoxide Reductase Complex, Subunit 1, GGCX gene, CYP4F2 gene, Alleles and APOE gene. The related lipids are Micelles, 208-G, Fatty Acids, Total cholesterol and Sphingolipids. The related experimental models are Knock-out.
Cross Reference
Introduction
To understand associated biological information of phylloquinone, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with phylloquinone?
phylloquinone is suspected in Vitamin K Deficiency, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes, vitamin depletion, Malnutrition, Osteoporosis and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with phylloquinone
PubChem Associated disorders and diseases
What pathways are associated with phylloquinone
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with phylloquinone?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with phylloquinone?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with phylloquinone?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with phylloquinone?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with phylloquinone?
Knock-out
Knock-out are used in the study 'A dedicated thioesterase of the Hotdog-fold family is required for the biosynthesis of the naphthoquinone ring of vitamin K1.' (Widhalm JR et al., 2009) and Knock-out are used in the study 'Deficiency in phylloquinone (vitamin K1) methylation affects prenyl quinone distribution, photosystem I abundance, and anthocyanin accumulation in the Arabidopsis AtmenG mutant.' (Lohmann A et al., 2006).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
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NCBI Entrez Crosslinks
All references with phylloquinone
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Santabarbara S et al. | Controlling electron transfer between the two cofactor chains of photosystem I by the redox state of one of their components. | 2015 | Biophys. J. | pmid:25809266 |
| Shea MK et al. | The association between vitamin K status and knee osteoarthritis features in older adults: the Health, Aging and Body Composition Study. | 2015 | Osteoarthr. Cartil. | pmid:25528106 |
| Lin T et al. | Periprocedural anticoagulation of patients undergoing pericardiocentesis for cardiac tamponade complicating catheter ablation of atrial fibrillation. | 2015 | Int Heart J | pmid:25503659 |
| Champion S et al. | Vitamin K1 antagonisation is not safe in high thromboembolic risk patients with over-anticoagulation. | 2014 May-Jun | Therapie | pmid:24901290 |
| Hemmati AA et al. | Topical vitamin K1 promotes repair of full thickness wound in rat. | 2014 Jul-Aug | Indian J Pharmacol | pmid:25097279 |
| Chao MT et al. | An innovative acupuncture treatment for primary dysmenorrhea: a randomized, crossover pilot study. | 2014 Jan-Feb | Altern Ther Health Med | pmid:24445356 |
| Davidson MH and Bechtel DH | Assessment of the effect of esterified propoxylated glycerol (EPG) on the status of fat-soluble vitamins and select water-soluble nutrients following dietary administration to humans for 8 weeks. | 2014 | Regul. Toxicol. Pharmacol. | pmid:25497998 |
| Dashti HS et al. | Meta-analysis of genome-wide association studies for circulating phylloquinone concentrations. | 2014 | Am. J. Clin. Nutr. | pmid:25411281 |
| Farley SM et al. | Deuterium-labeled phylloquinone fed to α-tocopherol-injected rats demonstrates sensitivity of low phylloquinone-containing tissues to menaquinone-4 depletion. | 2014 | Mol Nutr Food Res | pmid:25044667 |
| Chao MT et al. | Increase in plasma phylloquinone concentrations following acupoint injection for the treatment of primary dysmenorrhea. | 2014 | J Acupunct Meridian Stud | pmid:24929459 |
| Shea MK et al. | Associations between vitamin K status and haemostatic and inflammatory biomarkers in community-dwelling adults. The Multi-Ethnic Study of Atherosclerosis. | 2014 | Thromb. Haemost. | pmid:24849546 |
| Mi YN et al. | The severe adverse reaction to vitamin k1 injection is anaphylactoid reaction but not anaphylaxis. | 2014 | PLoS ONE | pmid:24594861 |
| Gershkovich P et al. | A simple and sensitive method for determination of vitamins D3 and K1 in rat plasma: application for an in vivo pharmacokinetic study. | 2014 | Drug Dev Ind Pharm | pmid:23373428 |
| Caluwé R et al. | Vitamin K2 supplementation in haemodialysis patients: a randomized dose-finding study. | 2014 | Nephrol. Dial. Transplant. | pmid:24285428 |
| Dalmeijer GW et al. | Phylloquinone concentrations and the risk of vascular calcification in healthy women. | 2014 | Arterioscler. Thromb. Vasc. Biol. | pmid:24855054 |
| Milanovsky GE et al. | Molecular dynamics study of the primary charge separation reactions in Photosystem I: effect of the replacement of the axial ligands to the electron acceptor Aâ‚€. | 2014 | Biochim. Biophys. Acta | pmid:24637178 |
| Rødbotten R et al. | Vitamin K2 in different bovine muscles and breeds. | 2014 | Meat Sci. | pmid:24508562 |
| Shearer MJ and Newman P | Recent trends in the metabolism and cell biology of vitamin K with special reference to vitamin K cycling and MK-4 biosynthesis. | 2014 | J. Lipid Res. | pmid:24489112 |
| Juanola-Falgarona M et al. | Dietary intake of vitamin K is inversely associated with mortality risk. | 2014 | J. Nutr. | pmid:24647393 |
| El-Shabrawi MH and Farrag MI | Hepatic manifestations in juvenile systemic lupus erythematosus. | 2014 | Recent Pat Inflamm Allergy Drug Discov | pmid:24383439 |