phylloquinone

Phylloquinone is a lipid of Prenol Lipids (PR) class. Phylloquinone is associated with abnormalities such as Vitamin K Deficiency, Malnutrition, Consumption-archaic term for TB, Osteoporosis and Hyperostosis, Diffuse Idiopathic Skeletal. The involved functions are known as Ingestion, Blood Circulation, Genetic Polymorphism, Intestinal Absorption and Process. Phylloquinone often locates in Blood, Body tissue, Hepatic, Membrane and Entire bony skeleton. The associated genes with phylloquinone are Vitamin K Epoxide Reductase Complex, Subunit 1, GGCX gene, CYP4F2 gene, Alleles and APOE gene. The related lipids are Micelles, 208-G, Fatty Acids, Total cholesterol and Sphingolipids. The related experimental models are Knock-out.

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Introduction

To understand associated biological information of phylloquinone, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with phylloquinone?

phylloquinone is suspected in Vitamin K Deficiency, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes, vitamin depletion, Malnutrition, Osteoporosis and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with phylloquinone

MeSH term MeSH ID Detail
Thromboembolism D013923 6 associated lipids
Vitamin K Deficiency D014813 5 associated lipids
Exanthema D005076 11 associated lipids
Total 3

PubChem Associated disorders and diseases

What pathways are associated with phylloquinone

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with phylloquinone?

Related references are published most in these journals:

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What functions are associated with phylloquinone?


Related references are published most in these journals:

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What lipids are associated with phylloquinone?

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What genes are associated with phylloquinone?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with phylloquinone?

Knock-out

Knock-out are used in the study 'A dedicated thioesterase of the Hotdog-fold family is required for the biosynthesis of the naphthoquinone ring of vitamin K1.' (Widhalm JR et al., 2009) and Knock-out are used in the study 'Deficiency in phylloquinone (vitamin K1) methylation affects prenyl quinone distribution, photosystem I abundance, and anthocyanin accumulation in the Arabidopsis AtmenG mutant.' (Lohmann A et al., 2006).

Related references are published most in these journals:

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NCBI Entrez Crosslinks

All references with phylloquinone

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Authors Title Published Journal PubMed Link
OMORI A [ANTIHEMOPHILIC GLOBULIN CONSUMPTION DURING BLOOD COAGULATION]. 1963 Nippon Naika Gakkai Zasshi pmid:14156201
DOKU HC et al. THROMBOPLASTIC ACTIVITY OF HUMAN SALIVA IN PATIENTS UNDER PROLONGED ANTICOAGULATION THERAPY. 1964 May-Jun J. Dent. Res. pmid:14159035
STEFANINI F et al. [CLINICAL RESEARCH ON POST-EXTRACTIVE HEMORRHAGES]. 1963 Oct-Dec Omnia Med Ther pmid:14159130
CABASSA N and SCIASCIA R [CHANGES IN THE ERYTHROCYTE UPTAKE OF T3-I-131 IN RATS AFTER ADMINISTRATION OF COAGULANTS (PROTAMINE SULFATE AND VITAMIN K 1)]. 1964 Jan-Feb Radiobiol Radioter Fis Med pmid:14171481
Barr R et al. Destruction of vitamin K1 of cultured carrot cells by ultraviolet radiation and its effect on plasma membrane electron transport reactions. 1992 Biochem. Int. pmid:1417882
KOZINN PJ et al. MASSIVE HEMORRHAGE--SCALPS OF NEWBORN INFANTS. 1964 Am. J. Dis. Child. pmid:14186662
SOREL et al. [100 HOSPITALIZED CASES OF WHOOPING COUGH. STATISTICS AND THERAPEUTIC CONSIDERATIONS]. 1964 Arch. Fr. Pediatr. pmid:14195286
MCKENNA M et al. A SECOND NAPHTHOQUINONE IN SPINACH CHLOROPLASTS. 1964 Nature pmid:14202379
PIGUET B and BERTHEUIL F [ALLERGIC CUTANEOUS COMPLICATIONS CAUSED BY A SYNTHETIC INJECTABLE VITAMIN K1 PREPARATION]. 1964 Jul-Aug Bull Soc Fr Dermatol Syphiligr pmid:14210517
von Kries R et al. Late hemorrhagic disease of newborn: a case with increased vitamin K requirement. 1992 Acta Paediatr. pmid:1421921