phylloquinone

Phylloquinone is a lipid of Prenol Lipids (PR) class. Phylloquinone is associated with abnormalities such as Vitamin K Deficiency, Malnutrition, Consumption-archaic term for TB, Osteoporosis and Hyperostosis, Diffuse Idiopathic Skeletal. The involved functions are known as Ingestion, Blood Circulation, Genetic Polymorphism, Intestinal Absorption and Process. Phylloquinone often locates in Blood, Body tissue, Hepatic, Membrane and Entire bony skeleton. The associated genes with phylloquinone are Vitamin K Epoxide Reductase Complex, Subunit 1, GGCX gene, CYP4F2 gene, Alleles and APOE gene. The related lipids are Micelles, 208-G, Fatty Acids, Total cholesterol and Sphingolipids. The related experimental models are Knock-out.

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Introduction

To understand associated biological information of phylloquinone, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with phylloquinone?

phylloquinone is suspected in Vitamin K Deficiency, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes, vitamin depletion, Malnutrition, Osteoporosis and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with phylloquinone

MeSH term MeSH ID Detail
Thromboembolism D013923 6 associated lipids
Vitamin K Deficiency D014813 5 associated lipids
Exanthema D005076 11 associated lipids
Total 3

PubChem Associated disorders and diseases

What pathways are associated with phylloquinone

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with phylloquinone?

Related references are published most in these journals:

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What functions are associated with phylloquinone?


Related references are published most in these journals:

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What lipids are associated with phylloquinone?

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What genes are associated with phylloquinone?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with phylloquinone?

Knock-out

Knock-out are used in the study 'A dedicated thioesterase of the Hotdog-fold family is required for the biosynthesis of the naphthoquinone ring of vitamin K1.' (Widhalm JR et al., 2009) and Knock-out are used in the study 'Deficiency in phylloquinone (vitamin K1) methylation affects prenyl quinone distribution, photosystem I abundance, and anthocyanin accumulation in the Arabidopsis AtmenG mutant.' (Lohmann A et al., 2006).

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NCBI Entrez Crosslinks

All references with phylloquinone

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Authors Title Published Journal PubMed Link
Fasco MJ et al. Warfarin inhibition of vitamin K 2,3-epoxide reductase in rat liver microsomes. 1983 Biochemistry pmid:6652076
Wilson AC and Park BK Quantitative analysis of pharmacological levels of vitamin K1 and vitamin K1 2,3-epoxide in rabbit plasma by high-performance liquid chromatography. 1983 J. Chromatogr. pmid:6643613
Pennock JF The biosynthesis of chloroplastidic terpenoid quinones and chromanols. 1983 Biochem. Soc. Trans. pmid:6642059
Chang JC Acquired coagulopathy owing to parenteral cefamandole: renal failure as a predisposing factor. 1983 Sep-Oct Ann. Clin. Lab. Sci. pmid:6638932
Boster SR and Bergin JJ Upper airway obstruction complicating warfarin therapy--with a note on reversal of warfarin toxicity. 1983 Ann Emerg Med pmid:6638633
O'Mara K and Mavichak V Trauma and oral anticoagulants. 1983 Ann Emerg Med pmid:6638631
Ueno T and Suttie JW High-pressure liquid chromatographic-reductive electrochemical detection analysis of serum trans-phylloquinone. 1983 Anal. Biochem. pmid:6638487
Kammermann-Lüscher B [Coumarin poisoning in dog and cat]. 1978 Schweiz. Arch. Tierheilkd. pmid:663601
Shanahan F et al. Factor V deficiency and its reversal with gluten restriction. In a patient with celiac disease. 1983 Arch. Intern. Med. pmid:6625791
Horn GB Determination of phytonadione in elemental diets by TLC-spectrophotodensitometry. 1978 J Pharm Sci pmid:660469