phylloquinone

Phylloquinone is a lipid of Prenol Lipids (PR) class. Phylloquinone is associated with abnormalities such as Vitamin K Deficiency, Malnutrition, Consumption-archaic term for TB, Osteoporosis and Hyperostosis, Diffuse Idiopathic Skeletal. The involved functions are known as Ingestion, Blood Circulation, Genetic Polymorphism, Intestinal Absorption and Process. Phylloquinone often locates in Blood, Body tissue, Hepatic, Membrane and Entire bony skeleton. The associated genes with phylloquinone are Vitamin K Epoxide Reductase Complex, Subunit 1, GGCX gene, CYP4F2 gene, Alleles and APOE gene. The related lipids are Micelles, 208-G, Fatty Acids, Total cholesterol and Sphingolipids. The related experimental models are Knock-out.

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Introduction

To understand associated biological information of phylloquinone, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with phylloquinone?

phylloquinone is suspected in Vitamin K Deficiency, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes, vitamin depletion, Malnutrition, Osteoporosis and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with phylloquinone

MeSH term MeSH ID Detail
Thromboembolism D013923 6 associated lipids
Vitamin K Deficiency D014813 5 associated lipids
Exanthema D005076 11 associated lipids
Total 3

PubChem Associated disorders and diseases

What pathways are associated with phylloquinone

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with phylloquinone?

Related references are published most in these journals:

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What functions are associated with phylloquinone?


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What lipids are associated with phylloquinone?

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What genes are associated with phylloquinone?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with phylloquinone?

Knock-out

Knock-out are used in the study 'A dedicated thioesterase of the Hotdog-fold family is required for the biosynthesis of the naphthoquinone ring of vitamin K1.' (Widhalm JR et al., 2009) and Knock-out are used in the study 'Deficiency in phylloquinone (vitamin K1) methylation affects prenyl quinone distribution, photosystem I abundance, and anthocyanin accumulation in the Arabidopsis AtmenG mutant.' (Lohmann A et al., 2006).

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NCBI Entrez Crosslinks

All references with phylloquinone

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Authors Title Published Journal PubMed Link
Golbeck JH The binding of cofactors to photosystem I analyzed by spectroscopic and mutagenic methods. 2003 Annu Rev Biophys Biomol Struct pmid:12524325
Bishop NI Photosynthesis: the electron transport system of green plants. 1971 Annu. Rev. Biochem. pmid:4399259
Olson RE The function and metabolism of vitamin K. 1984 Annu. Rev. Nutr. pmid:6380538
Rybnikov VN et al. [Naphthoquinones as immunomodulators during intensive exertion]. 1997 Antibiot. Khimioter. pmid:9265467
Rybnikov VN and Brovkina IL [Correlation of immunomodulating effects induced by lysozyme and naphthoquinones in acute blood loss]. 2003 Antibiot. Khimioter. pmid:12968462
Okayasu H et al. Cytotoxic activity of vitamins K1, K2 and K3 against human oral tumor cell lines. 2001 Jul-Aug Anticancer Res. pmid:11724297
Janin-Mercier A et al. Subcutaneous sclerosis with fasciitis and eosinophilia after phytonadione injections. 1985 Arch Dermatol pmid:2932062
Uyeda K et al. Kaposi sarcoma-like granuloma on diaper dermatitis. A report of five cases. 1973 Arch Dermatol pmid:4735356
Finkelstein H et al. Is benzyl alcohol an allergen? 1985 Arch Dermatol pmid:3159348
Robison JW and Odom RB Delayed cutaneous reaction to phytonadione. 1978 Arch Dermatol pmid:736587