phylloquinone

Phylloquinone is a lipid of Prenol Lipids (PR) class. Phylloquinone is associated with abnormalities such as Vitamin K Deficiency, Malnutrition, Consumption-archaic term for TB, Osteoporosis and Hyperostosis, Diffuse Idiopathic Skeletal. The involved functions are known as Ingestion, Blood Circulation, Genetic Polymorphism, Intestinal Absorption and Process. Phylloquinone often locates in Blood, Body tissue, Hepatic, Membrane and Entire bony skeleton. The associated genes with phylloquinone are Vitamin K Epoxide Reductase Complex, Subunit 1, GGCX gene, CYP4F2 gene, Alleles and APOE gene. The related lipids are Micelles, 208-G, Fatty Acids, Total cholesterol and Sphingolipids. The related experimental models are Knock-out.

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Introduction

To understand associated biological information of phylloquinone, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with phylloquinone?

phylloquinone is suspected in Vitamin K Deficiency, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes, vitamin depletion, Malnutrition, Osteoporosis and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with phylloquinone

MeSH term MeSH ID Detail
Thromboembolism D013923 6 associated lipids
Vitamin K Deficiency D014813 5 associated lipids
Exanthema D005076 11 associated lipids
Total 3

PubChem Associated disorders and diseases

What pathways are associated with phylloquinone

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with phylloquinone?

Related references are published most in these journals:

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What functions are associated with phylloquinone?


Related references are published most in these journals:

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What lipids are associated with phylloquinone?

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What genes are associated with phylloquinone?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with phylloquinone?

Knock-out

Knock-out are used in the study 'A dedicated thioesterase of the Hotdog-fold family is required for the biosynthesis of the naphthoquinone ring of vitamin K1.' (Widhalm JR et al., 2009) and Knock-out are used in the study 'Deficiency in phylloquinone (vitamin K1) methylation affects prenyl quinone distribution, photosystem I abundance, and anthocyanin accumulation in the Arabidopsis AtmenG mutant.' (Lohmann A et al., 2006).

Related references are published most in these journals:

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NCBI Entrez Crosslinks

All references with phylloquinone

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Authors Title Published Journal PubMed Link
Robison JW and Odom RB Delayed cutaneous reaction to phytonadione. 1978 Arch Dermatol pmid:736587
Owens DE et al. Retropharyngeal hematoma. A complication of therapy with anticoagulants. 1975 Arch Otolaryngol pmid:1164240
Le Guévello P et al. [Syringes for oral administration of vitamin K1 lipid emulsion]. 1995 Arch Pediatr pmid:7496467
Neguin C et al. [Voluntary poisoning with a rodenticide in an adolescent]. 1999 Arch Pediatr pmid:10472397
Maurage C et al. [Efficacy of oral administration of a micellaar solution of vitamin K during the neonatal period]. 1995 Arch Pediatr pmid:7780540
Besson-Leaud M et al. [Prophylaxis of late hemorrhagic disease in newborn infants with vitamin K1 at birth]. 1996 Arch Pediatr pmid:8745836
Botte A et al. [Two children with cerebral and retinal hemorrhages: do not diagnose shaken baby syndrome too rapidly]. 2012 Arch Pediatr pmid:22115729
Sciorelli G and Ricevuti G [Vitamin K and blood capillaries]. 1974 Apr-Jun Arch Sci Med (Torino) pmid:4417713
BELDING HH USE OF ANTICOAGULANTS IN THE PREVENTION OF VENOUS THROMBOEMBOLIC DISEASE IN POSTOPERATIVE PATIENTS. 1965 Arch Surg pmid:14267658
Bell RG and Matschiner JT Vitamin K activity of phylloquinone oxide. 1970 Arch. Biochem. Biophys. pmid:5497142