phylloquinone

Phylloquinone is a lipid of Prenol Lipids (PR) class. Phylloquinone is associated with abnormalities such as Vitamin K Deficiency, Malnutrition, Consumption-archaic term for TB, Osteoporosis and Hyperostosis, Diffuse Idiopathic Skeletal. The involved functions are known as Ingestion, Blood Circulation, Genetic Polymorphism, Intestinal Absorption and Process. Phylloquinone often locates in Blood, Body tissue, Hepatic, Membrane and Entire bony skeleton. The associated genes with phylloquinone are Vitamin K Epoxide Reductase Complex, Subunit 1, GGCX gene, CYP4F2 gene, Alleles and APOE gene. The related lipids are Micelles, 208-G, Fatty Acids, Total cholesterol and Sphingolipids. The related experimental models are Knock-out.

Cross Reference

Introduction

To understand associated biological information of phylloquinone, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with phylloquinone?

phylloquinone is suspected in Vitamin K Deficiency, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes, vitamin depletion, Malnutrition, Osteoporosis and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with phylloquinone

MeSH term MeSH ID Detail
Thromboembolism D013923 6 associated lipids
Vitamin K Deficiency D014813 5 associated lipids
Exanthema D005076 11 associated lipids
Total 3

PubChem Associated disorders and diseases

What pathways are associated with phylloquinone

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with phylloquinone?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with phylloquinone?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with phylloquinone?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What genes are associated with phylloquinone?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with phylloquinone?

Knock-out

Knock-out are used in the study 'A dedicated thioesterase of the Hotdog-fold family is required for the biosynthesis of the naphthoquinone ring of vitamin K1.' (Widhalm JR et al., 2009) and Knock-out are used in the study 'Deficiency in phylloquinone (vitamin K1) methylation affects prenyl quinone distribution, photosystem I abundance, and anthocyanin accumulation in the Arabidopsis AtmenG mutant.' (Lohmann A et al., 2006).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

NCBI Entrez Crosslinks

All references with phylloquinone

Download all related citations
Per page 10 20 50 100 | Total 1365
Authors Title Published Journal PubMed Link
Dismore ML et al. Vitamin K content of nuts and fruits in the US diet. 2003 J Am Diet Assoc pmid:14647095
Spronk HM et al. Tissue-specific utilization of menaquinone-4 results in the prevention of arterial calcification in warfarin-treated rats. 2003 Nov-Dec J. Vasc. Res. pmid:14654717
Ben-Shem A et al. Crystal structure of plant photosystem I. 2003 Nature pmid:14668855
Lochner K et al. Phylloquinone, what can we learn from plants? 2003 Biofactors pmid:14695922
Carrié I et al. Menaquinone-4 concentration is correlated with sphingolipid concentrations in rat brain. 2004 J. Nutr. pmid:14704312
Nakamura K et al. Variations in warfarin concentration in blood and coagulant factors after artificial valve replacement. 1992 Artery pmid:1471922
Shahal Y et al. Effect of vitamin K on neonatal erythrocytes. 1992 Biol. Neonate pmid:1472579
Sabo A et al. Phytomenadione improves red cell deformability in laboratory animals. 1992 Int J Clin Pharmacol Ther Toxicol pmid:1473874
Carrié I et al. Effects of long-term vitamin K (phylloquinone) intake on retina aging. 2003 Nutr Neurosci pmid:14744039
Van Der Est A et al. Removal of PsaF alters forward electron transfer in photosystem I: evidence for fast reoxidation of QK-A in subunit deletion mutants of Synechococcus sp. PCC 7002. 2004 Biochemistry pmid:14756562