| MeSH term | MeSH ID | Detail |
|---|---|---|
| Thromboembolism | D013923 | 6 associated lipids |
| Vitamin K Deficiency | D014813 | 5 associated lipids |
| Exanthema | D005076 | 11 associated lipids |
Total
3
phylloquinone
Phylloquinone is a lipid of Prenol Lipids (PR) class. Phylloquinone is associated with abnormalities such as Vitamin K Deficiency, Malnutrition, Consumption-archaic term for TB, Osteoporosis and Hyperostosis, Diffuse Idiopathic Skeletal. The involved functions are known as Ingestion, Blood Circulation, Genetic Polymorphism, Intestinal Absorption and Process. Phylloquinone often locates in Blood, Body tissue, Hepatic, Membrane and Entire bony skeleton. The associated genes with phylloquinone are Vitamin K Epoxide Reductase Complex, Subunit 1, GGCX gene, CYP4F2 gene, Alleles and APOE gene. The related lipids are Micelles, 208-G, Fatty Acids, Total cholesterol and Sphingolipids. The related experimental models are Knock-out.
Cross Reference
Introduction
To understand associated biological information of phylloquinone, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with phylloquinone?
phylloquinone is suspected in Vitamin K Deficiency, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes, vitamin depletion, Malnutrition, Osteoporosis and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with phylloquinone
PubChem Associated disorders and diseases
What pathways are associated with phylloquinone
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with phylloquinone?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with phylloquinone?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with phylloquinone?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with phylloquinone?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with phylloquinone?
Knock-out
Knock-out are used in the study 'A dedicated thioesterase of the Hotdog-fold family is required for the biosynthesis of the naphthoquinone ring of vitamin K1.' (Widhalm JR et al., 2009) and Knock-out are used in the study 'Deficiency in phylloquinone (vitamin K1) methylation affects prenyl quinone distribution, photosystem I abundance, and anthocyanin accumulation in the Arabidopsis AtmenG mutant.' (Lohmann A et al., 2006).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
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NCBI Entrez Crosslinks
All references with phylloquinone
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Booth SL et al. | Food sources and dietary intakes of vitamin K-1 (phylloquinone) in the American diet: data from the FDA Total Diet Study. | 1996 | J Am Diet Assoc | pmid:8557941 |
| MacCrehan WA and Schönberger E | Determination of vitamin K1 in serum using catalytic-reduction liquid chromatography with fluorescence detection. | 1995 | J. Chromatogr. B, Biomed. Appl. | pmid:8548011 |
| Alparin JB | Transfusion medicine issues in the practice of anesthesiology. | 1995 | Transfus Med Rev | pmid:8541716 |
| Hallak HO et al. | High clearance of (S)-warfarin in a warfarin-resistant subject. | 1993 | Br J Clin Pharmacol | pmid:8471414 |
| von Kries R and Hanawa Y | Neonatal vitamin K prophylaxis. Report of Scientific and Standardization Subcommittee on Perinatal Haemostasis. | 1993 | Thromb. Haemost. | pmid:8470054 |
| Conly JM and Stein KE | The absorption and bioactivity of bacterially synthesized menaquinones. | 1993 | Clin Invest Med | pmid:8467580 |
| Pietschnig B et al. | Vitamin K in breast milk: no influence of maternal dietary intake. | 1993 | Eur J Clin Nutr | pmid:8458317 |
| Lennon C et al. | The vitamin K content of intravenous lipid emulsions. | 1993 Mar-Apr | JPEN J Parenter Enteral Nutr | pmid:8455316 |
| Gregory EM et al. | Production and some properties of catalase and superoxide dismutase from the anaerobe Bacteroides distasonis. | 1977 | J. Bacteriol. | pmid:845116 |
| Babcock J et al. | Rodenticide-induced coagulopathy in a young child. A case of Munchausen syndrome by proxy. | 1993 | Am J Pediatr Hematol Oncol | pmid:8447555 |
| Sabo A et al. | Red blood cell deformability in diabetes mellitus: effect of phytomenadione. | 1993 | Int J Clin Pharmacol Ther Toxicol | pmid:8444511 |
| Billion-Rey F et al. | Stability of fat-soluble vitamins A (retinol palmitate), E (tocopherol acetate), and K1 (phylloquinone) in total parenteral nutrition at home. | 1993 Jan-Feb | JPEN J Parenter Enteral Nutr | pmid:8437325 |
| Lemlich G et al. | Cutaneous reactions to vitamin K1 injections. | 1993 | J. Am. Acad. Dermatol. | pmid:8436655 |
| Bancroft J and Cohen MB | Intracranial hemorrhage due to vitamin K deficiency in breast-fed infants with cholestasis. | 1993 | J. Pediatr. Gastroenterol. Nutr. | pmid:8433245 |
| Guillaumont M et al. | Changes in hepatic vitamin K1 levels after prophylactic administration to the newborn. | 1993 | J. Pediatr. Gastroenterol. Nutr. | pmid:8433228 |
| Anai T et al. | Can prenatal vitamin K1 (phylloquinone) supplementation replace prophylaxis at birth? | 1993 | Obstet Gynecol | pmid:8423960 |
| Bovill EG et al. | Vitamin K1 metabolism and the production of des-carboxy prothrombin and protein C in the term and premature neonate. | 1993 | Blood | pmid:8417804 |
| Saupe J et al. | Phylloquinone transport and its influence on gamma-carboxyglutamate residues of osteocalcin in patients on maintenance hemodialysis. | 1993 | Am. J. Clin. Nutr. | pmid:8393269 |
| Sieckmann I et al. | Transient electron paramagnetic resonance of the triplet state of P700 in photosystem I: evidence for triplet delocalization at room temperature. | 1993 | Biochemistry | pmid:8387818 |
| Cornelissen EA et al. | Prevention of vitamin K deficiency in infancy by weekly administration of vitamin K. | 1993 | Acta Paediatr. | pmid:8374213 |
| Tokumura T et al. | Evaluation of bioavailability upon oral administration of phytonadione preparations in beagle dogs. | 1993 | Biol. Pharm. Bull. | pmid:8364482 |
| Sétif P and Brettel K | Forward electron transfer from phylloquinone A1 to iron-sulfur centers in spinach photosystem I. | 1993 | Biochemistry | pmid:8347589 |
| Groenen-van Dooren MM et al. | The relative effects of phylloquinone and menaquinone-4 on the blood coagulation factor synthesis in vitamin K-deficient rats. | 1993 | Biochem. Pharmacol. | pmid:8347166 |
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| Schubiger G et al. | Vitamin K1 concentration in breast-fed neonates after oral or intramuscular administration of a single dose of a new mixed-micellar preparation of phylloquinone. | 1993 | J. Pediatr. Gastroenterol. Nutr. | pmid:8315554 |
| Pastoureau P et al. | Osteopenia and bone-remodeling abnormalities in warfarin-treated lambs. | 1993 | J. Bone Miner. Res. | pmid:8304041 |
| Pengo V et al. | Reversal of excessive effect of regular anticoagulation: low oral dose of phytonadione (vitamin K1) compared with warfarin discontinuation. | 1993 | Blood Coagul. Fibrinolysis | pmid:8292723 |
| Chung JH et al. | Effects of vitamin K1 and menadione on ethanol metabolism and toxicity. | 1993 | Drug Chem Toxicol | pmid:8281891 |
| Hodges SJ et al. | Circulating levels of vitamins K1 and K2 decreased in elderly women with hip fracture. | 1993 | J. Bone Miner. Res. | pmid:8256661 |
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| Fujita K et al. | Vitamin K1 and K2 status and faecal flora in breast fed and formula fed 1-month-old infants. | 1993 | Eur. J. Pediatr. | pmid:8223791 |
| Thijssen HH and Drittij-Reijnders MJ | Vitamin K metabolism and vitamin K1 status in human liver samples: a search for inter-individual differences in warfarin sensitivity. | 1993 | Br. J. Haematol. | pmid:8217828 |
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| Sheen SR et al. | Symptomatic brodifacoum ingestion requiring high-dose phytonadione therapy. | 1994 | Vet Hum Toxicol | pmid:8066968 |
| Moënne-Loccoz P et al. | Path of electron transfer in photosystem 1: direct evidence of forward electron transfer from A1 to Fe-Sx. | 1994 | Biochemistry | pmid:8060972 |
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| Thijssen HH and Drittij-Reijnders MJ | Vitamin K distribution in rat tissues: dietary phylloquinone is a source of tissue menaquinone-4. | 1994 | Br. J. Nutr. | pmid:7947656 |
| Guidetti MS et al. | Sclerodermatous skin reaction after vitamin K1 injections. | 1994 | Contact Derm. | pmid:7924294 |
| Breton J et al. | Binding sites of quinones in photosynthetic bacterial reaction centers investigated by light-induced FTIR difference spectroscopy: binding of chainless symmetrical quinones to the QA site of Rhodobacter sphaeroides. | 1994 | Biochemistry | pmid:7918463 |
| van der Est A et al. | Electron transfer from the acceptor A1 to the iron-sulfur centers in photosystem I as studied by transient EPR spectroscopy. | 1994 | Biochemistry | pmid:7918396 |
| Conly J and Stein K | Reduction of vitamin K2 concentrations in human liver associated with the use of broad spectrum antimicrobials. | 1994 | Clin Invest Med | pmid:7895417 |
| Roth DA et al. | Mutagenesis of vitamin K-dependent carboxylase demonstrates a carboxyl terminus-mediated interaction with vitamin K hydroquinone. | 1995 | J. Biol. Chem. | pmid:7890642 |