| MeSH term | MeSH ID | Detail |
|---|---|---|
| Thromboembolism | D013923 | 6 associated lipids |
| Vitamin K Deficiency | D014813 | 5 associated lipids |
| Exanthema | D005076 | 11 associated lipids |
Total
3
phylloquinone
Phylloquinone is a lipid of Prenol Lipids (PR) class. Phylloquinone is associated with abnormalities such as Vitamin K Deficiency, Malnutrition, Consumption-archaic term for TB, Osteoporosis and Hyperostosis, Diffuse Idiopathic Skeletal. The involved functions are known as Ingestion, Blood Circulation, Genetic Polymorphism, Intestinal Absorption and Process. Phylloquinone often locates in Blood, Body tissue, Hepatic, Membrane and Entire bony skeleton. The associated genes with phylloquinone are Vitamin K Epoxide Reductase Complex, Subunit 1, GGCX gene, CYP4F2 gene, Alleles and APOE gene. The related lipids are Micelles, 208-G, Fatty Acids, Total cholesterol and Sphingolipids. The related experimental models are Knock-out.
Cross Reference
Introduction
To understand associated biological information of phylloquinone, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with phylloquinone?
phylloquinone is suspected in Vitamin K Deficiency, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes, vitamin depletion, Malnutrition, Osteoporosis and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with phylloquinone
PubChem Associated disorders and diseases
What pathways are associated with phylloquinone
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with phylloquinone?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with phylloquinone?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with phylloquinone?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with phylloquinone?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with phylloquinone?
Knock-out
Knock-out are used in the study 'A dedicated thioesterase of the Hotdog-fold family is required for the biosynthesis of the naphthoquinone ring of vitamin K1.' (Widhalm JR et al., 2009) and Knock-out are used in the study 'Deficiency in phylloquinone (vitamin K1) methylation affects prenyl quinone distribution, photosystem I abundance, and anthocyanin accumulation in the Arabidopsis AtmenG mutant.' (Lohmann A et al., 2006).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
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NCBI Entrez Crosslinks
All references with phylloquinone
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Gettler SL and Fung MA | Off-center fold: indurated plaques on the arms of a 52-year-old man. Diagnosis: Cutaneous reaction to phytonadione injection. | 2001 | Arch Dermatol | pmid:11453820 |
| Johnson TW et al. | Recruitment of a foreign quinone into the A1 site of photosystem I. In vivo replacement of plastoquinone-9 by media-supplemented naphthoquinones in phylloquinone biosynthetic pathway mutants of Synechocystis sp. PCC 6803. | 2001 | J. Biol. Chem. | pmid:11470786 |
| Valko M et al. | Oxygen free radical generating mechanisms in the colon: do the semiquinones of vitamin K play a role in the aetiology of colon cancer? | 2001 | Biochim. Biophys. Acta | pmid:11479033 |
| Boudreaux B et al. | Mutations in both sides of the photosystem I reaction center identify the phylloquinone observed by electron paramagnetic resonance spectroscopy. | 2001 | J. Biol. Chem. | pmid:11489879 |
| Udagawa M and Murai T | Content of phylloquinone and menaquinone in the tissues of mummichog Fundulus heteroclitus fed diets containing different forms of vitamin K. | 2001 | J. Nutr. Sci. Vitaminol. | pmid:11508712 |
| Vermeer C and Ulrich MM | The effect of microgravity on plasma-osteocalcin. | 1986 | Adv Space Res | pmid:11537812 |
| Vermeer C et al. | Bone markers during a 6-month space flight: effects of vitamin K supplementation. | 1998 | J Gravit Physiol | pmid:11541904 |
| Hylek EM et al. | Clinical predictors of prolonged delay in return of the international normalized ratio to within the therapeutic range after excessive anticoagulation with warfarin. | 2001 | Ann. Intern. Med. | pmid:11560452 |
| Summaries for patients. Predicting risk for prolonged high INR after too much anticoagulation. | 2001 | Ann. Intern. Med. | pmid:11575277 | |
| Owens DE et al. | Retropharyngeal hematoma. A complication of therapy with anticoagulants. | 1975 | Arch Otolaryngol | pmid:1164240 |
| Kawana K et al. | Circulating levels of vitamin K1, menaquinone-4, and menaquinone-7 in healthy elderly Japanese women and patients with vertebral fractures and patients with hip fractures. | 2001 | Endocr. Res. | pmid:11678581 |
| Ghosh K et al. | Congenital deficiency of vitamin K dependent coagulation factors--its rarity and need for an international registry. | 2001 | Thromb. Haemost. | pmid:11686345 |
| Brettel K and Leibl W | Electron transfer in photosystem I. | 2001 | Biochim. Biophys. Acta | pmid:11687210 |
| Itoh S et al. | Modification of photosystem I reaction center by the extraction and exchange of chlorophylls and quinones. | 2001 | Biochim. Biophys. Acta | pmid:11687211 |
| Bittl R and Zech SG | Pulsed EPR spectroscopy on short-lived intermediates in Photosystem I. | 2001 | Biochim. Biophys. Acta | pmid:11687215 |
| Deligiannakis Y and Rutherford AW | Electron spin echo envelope modulation spectroscopy in photosystem I. | 2001 | Biochim. Biophys. Acta | pmid:11687217 |
| Rigby SE et al. | Electron nuclear double resonance (ENDOR) spectroscopy of radicals in photosystem I and related Type 1 photosynthetic reaction centres. | 2001 | Biochim. Biophys. Acta | pmid:11687218 |
| Booth SL et al. | Effects of a hydrogenated form of vitamin K on bone formation and resorption. | 2001 | Am. J. Clin. Nutr. | pmid:11722960 |
| Okayasu H et al. | Cytotoxic activity of vitamins K1, K2 and K3 against human oral tumor cell lines. | 2001 Jul-Aug | Anticancer Res. | pmid:11724297 |
| Greer FR | Are breast-fed infants vitamin K deficient? | 2001 | Adv. Exp. Med. Biol. | pmid:11787707 |