phylloquinone

Phylloquinone is a lipid of Prenol Lipids (PR) class. Phylloquinone is associated with abnormalities such as Vitamin K Deficiency, Malnutrition, Consumption-archaic term for TB, Osteoporosis and Hyperostosis, Diffuse Idiopathic Skeletal. The involved functions are known as Ingestion, Blood Circulation, Genetic Polymorphism, Intestinal Absorption and Process. Phylloquinone often locates in Blood, Body tissue, Hepatic, Membrane and Entire bony skeleton. The associated genes with phylloquinone are Vitamin K Epoxide Reductase Complex, Subunit 1, GGCX gene, CYP4F2 gene, Alleles and APOE gene. The related lipids are Micelles, 208-G, Fatty Acids, Total cholesterol and Sphingolipids. The related experimental models are Knock-out.

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Introduction

To understand associated biological information of phylloquinone, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with phylloquinone?

phylloquinone is suspected in Vitamin K Deficiency, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes, vitamin depletion, Malnutrition, Osteoporosis and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with phylloquinone

MeSH term MeSH ID Detail
Thromboembolism D013923 6 associated lipids
Vitamin K Deficiency D014813 5 associated lipids
Exanthema D005076 11 associated lipids
Total 3

PubChem Associated disorders and diseases

What pathways are associated with phylloquinone

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with phylloquinone?

Related references are published most in these journals:

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What functions are associated with phylloquinone?


Related references are published most in these journals:

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What lipids are associated with phylloquinone?

Related references are published most in these journals:

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What genes are associated with phylloquinone?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with phylloquinone?

Knock-out

Knock-out are used in the study 'A dedicated thioesterase of the Hotdog-fold family is required for the biosynthesis of the naphthoquinone ring of vitamin K1.' (Widhalm JR et al., 2009) and Knock-out are used in the study 'Deficiency in phylloquinone (vitamin K1) methylation affects prenyl quinone distribution, photosystem I abundance, and anthocyanin accumulation in the Arabidopsis AtmenG mutant.' (Lohmann A et al., 2006).

Related references are published most in these journals:

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NCBI Entrez Crosslinks

All references with phylloquinone

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Authors Title Published Journal PubMed Link
Jiang NX et al. [Vitamin K epoxide reductase complex 1 gene polymorphism and warfarin dose requirement in Chinese patients]. 2007 Zhonghua Xin Xue Guan Bing Za Zhi pmid:17961434
Liu J et al. [Level of vitamin K-dependent coagulation factors in premature infants and the influence of maternal antenatal administration of vitamin K1 on their activity]. 2005 Zhonghua Er Ke Za Zhi pmid:16412352
Chen XH et al. [Analysis of thirteen cases with secondary coagulation disorder caused by raticide exposure]. 2010 Zhonghua Er Ke Za Zhi pmid:21055312
Sun AY and Cheng JS Neuroprotective effects of poly (ADP-ribose) polymerase inhibitors in transient focal cerebral ischemia of rats. 1998 Zhongguo Yao Li Xue Bao pmid:10374629
Chen JW et al. [Analysis of vitamins and inorganic elements in the water extracts of Radix Changii]. 2004 Zhong Xi Yi Jie He Xue Bao pmid:15383265
Rogner G [Changes of blood coagulation potential during the prevention of hemorrhage in newborn infants born at risk]. 1974 Zentralbl Gynakol pmid:4450830
Sewkow S et al. [Nutritional requirements of Bacteroides melaninogenicus]. 1974 Zentralbl Bakteriol Orig A pmid:4154688
Hoppe W [The importance of the treatment with marcumar in oral surgery]. 1967 Zahnarztl Prax pmid:5298417
Lichtenthaler HK and Tevini M [Effect of UV-rays on the lipoquinone-pigment composition of isolated spinach chloroplasts]. 1969 Z. Naturforsch. B pmid:4390030
Lichtenthaler HK [Formation of excess plastidquinones in the leaves of Ficus elastica Roxb]. 1969 Z. Naturforsch. B pmid:4391381