| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| pmid: | ||||
| Murphy RC et al. | Mass spectrometry advances in lipidomica: collision-induced decomposition of Kdo2-lipid A. | 2005 | Prostaglandins Other Lipid Mediat. | pmid:16099398 |
| Zughaier S et al. | Hexa-acylation and KDO(2)-glycosylation determine the specific immunostimulatory activity of Neisseria meningitidis lipid A for human monocyte derived dendritic cells. | 2006 | Vaccine | pmid:16246469 |
| Raetz CR et al. | Kdo2-Lipid A of Escherichia coli, a defined endotoxin that activates macrophages via TLR-4. | 2006 | J. Lipid Res. | pmid:16479018 |
| Raetz CR et al. | Lipid A modification systems in gram-negative bacteria. | 2007 | Annu. Rev. Biochem. | pmid:17362200 |
| Murphy RC et al. | Detection of the abundance of diacylglycerol and triacylglycerol molecular species in cells using neutral loss mass spectrometry. | 2007 | Anal. Biochem. | pmid:17442253 |
| Albright S et al. | NMR spectral mapping of Lipid A molecular patterns affected by interaction with the innate immune receptor CD14. | 2009 | Biochem. Biophys. Res. Commun. | pmid:19059378 |
| Delcour AH | Outer membrane permeability and antibiotic resistance. | 2009 | Biochim. Biophys. Acta | pmid:19100346 |
| Grkovich A et al. | TLR-4 mediated group IVA phospholipase A(2) activation is phosphatidic acid phosphohydrolase 1 and protein kinase C dependent. | 2009 | Biochim. Biophys. Acta | pmid:19230851 |
| Wang X and Quinn PJ | Lipopolysaccharide: Biosynthetic pathway and structure modification. | 2010 | Prog. Lipid Res. | pmid:19815028 |
| Saito O et al. | Spinal glial TLR4-mediated nociception and production of prostaglandin E(2) and TNF. | 2010 | Br. J. Pharmacol. | pmid:20649577 |
| Sims K et al. | Kdo2-lipid A, a TLR4-specific agonist, induces de novo sphingolipid biosynthesis in RAW264.7 macrophages, which is essential for induction of autophagy. | 2010 | J. Biol. Chem. | pmid:20876532 |
| Dennis EA et al. | A mouse macrophage lipidome. | 2010 | J. Biol. Chem. | pmid:20923771 |
| Opiyo SO et al. | Evolution of the Kdo2-lipid A biosynthesis in bacteria. | 2010 | BMC Evol. Biol. | pmid:21106097 |
| Kim EY et al. | ATF3 plays a key role in Kdo2-lipid A-induced TLR4-dependent gene expression via NF-κB activation. | 2010 | PLoS ONE | pmid:21152039 |
| Sabidó E et al. | Targeted proteomics of the eicosanoid biosynthetic pathway completes an integrated genomics-proteomics-metabolomics picture of cellular metabolism. | 2012 | Mol. Cell Proteomics | pmid:22361236 |
| Norris PC and Dennis EA | Omega-3 fatty acids cause dramatic changes in TLR4 and purinergic eicosanoid signaling. | 2012 | Proc. Natl. Acad. Sci. U.S.A. | pmid:22586114 |
| Zheng X et al. | Crosstalk between JNK and NF-κB in the KDO2-mediated production of TNFα in HAPI cells. | 2012 | Cell. Mol. Neurobiol. | pmid:22837047 |
| Wang X | [Kdo2-lipid A modification in gram-negative bacteria--a review]. | 2013 | Wei Sheng Wu Xue Bao | pmid:23627103 |
| Maurya MR et al. | Analysis of inflammatory and lipid metabolic networks across RAW264.7 and thioglycolate-elicited macrophages. | 2013 | J. Lipid Res. | pmid:23776196 |
KDO2-lipid A
KDO2-lipid A is a lipid of Saccharolipids (SL) class. The involved functions are known as Biochemical Pathway, Immune response, Anabolism, Signal Transduction and Stimulus. Kdo2-lipid a often locates in Immune system and Protoplasm. The associated genes with KDO2-lipid A are PSMD6 gene, ABCA1 gene, ABCG1 gene, DHCR24 gene and SOAT1 gene. The related lipids are Lipopolysaccharides, Sterols, Fatty Acids, 25-hydroxycholesterol and lipid IVA.
Cross Reference
Introduction
To understand associated biological information of KDO2-lipid A, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with KDO2-lipid A?
There are no associated biomedical information in the current reference collection.
No disease MeSH terms mapped to the current reference collection.
PubChem Associated disorders and diseases
What pathways are associated with KDO2-lipid A
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with KDO2-lipid A?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with KDO2-lipid A?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with KDO2-lipid A?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with KDO2-lipid A?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with KDO2-lipid A?
There are no associated biomedical information in the current reference collection.