| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| pmid: | ||||
| Wang F et al. | Involvement of focal adhesion kinase in inhibition of motility of human breast cancer cells by sphingosine 1-phosphate. | 1999 | Exp. Cell Res. | pmid:10047444 |
| Rakhit S et al. | Sphingosine 1-phosphate stimulation of the p42/p44 mitogen-activated protein kinase pathway in airway smooth muscle. Role of endothelial differentiation gene 1, c-Src tyrosine kinase and phosphoinositide 3-kinase. | 1999 | Biochem. J. | pmid:10051434 |
| Perks CM et al. | Activation of integrin and ceramide signalling pathways can inhibit the mitogenic effect of insulin-like growth factor I (IGF-I) in human breast cancer cell lines. | 1999 | Br. J. Cancer | pmid:10070857 |
| Lane M et al. | Na+/H+ antiporter activity in hamster embryos is activated during fertilization. | 1999 | Dev. Biol. | pmid:10075856 |
| Megidish T et al. | Endogenous substrates of sphingosine-dependent kinases (SDKs) are chaperone proteins: heat shock proteins, glucose-regulated proteins, protein disulfide isomerase, and calreticulin. | 1999 | Biochemistry | pmid:10079081 |
| Spiegel S | Sphingosine 1-phosphate: a prototype of a new class of second messengers. | 1999 | J. Leukoc. Biol. | pmid:10080537 |
| Watanabe Y and Akaike T | Possible involvement of caspase-like family in maintenance of cytoskeleton integrity. | 1999 | J. Cell. Physiol. | pmid:10082131 |
| Shinpo K et al. | Protective effects of the TNF-ceramide pathway against glutamate neurotoxicity on cultured mesencephalic neurons. | 1999 | Brain Res. | pmid:10082875 |
| Yuzawa K et al. | Rescue effect of FTY720 on acute renal rejection in dogs. | 1999 Feb-Mar | Transplant. Proc. | pmid:10083381 |
| Kunikata S et al. | Immunosuppressive action of FTY720 for renal allograft a rat model. | Transplant. Proc. | pmid:10083517 | |
| Yamashita K et al. | Effect of a novel immunosuppressant, FTY720, on heart and liver transplantations in rats. | 1999 Feb-Mar | Transplant. Proc. | pmid:10083526 |
| Suzuki T et al. | Dose-dependent study of a novel immunosuppressant, FTY720, with the canine renal allograft transplantation model. | Transplant. Proc. | pmid:10083540 | |
| Hoshino Y et al. | FTY720, a novel immunosuppressant, shows a synergistic effect in combination with FK 506 in rat allograft models. | 1999 Feb-Mar | Transplant. Proc. | pmid:10083547 |
| Yanagawa Y et al. | FTY720, a novel immunosuppressant, prolongs rat skin allograft survival by decreasing T-cell infiltration into grafts. | Transplant. Proc. | pmid:10083548 | |
| Chiba K et al. | FTY720, a novel immunosuppressant, induces sequestration of circulating lymphocytes by acceleration of lymphocyte homing. | 1999 Feb-Mar | Transplant. Proc. | pmid:10083549 |
| Karasawa K et al. | Purification and characterization from rat kidney membranes of a novel platelet-activating factor (PAF)-dependent transacetylase that catalyzes the hydrolysis of PAF, formation of PAF analogs, and C2-ceramide. | 1999 | J. Biol. Chem. | pmid:10085103 |
| Medvedev AE et al. | Limited role of ceramide in lipopolysaccharide-mediated mitogen-activated protein kinase activation, transcription factor induction, and cytokine release. | 1999 | J. Biol. Chem. | pmid:10092612 |
| Törnquist K et al. | Tumor necrosis factor-alpha, sphingomyelinase, and ceramide inhibit store-operated calcium entry in thyroid FRTL-5 cells. | 1999 | J. Biol. Chem. | pmid:10092616 |
| Mahajan S et al. | Rational design and synthesis of a novel anti-leukemic agent targeting Bruton's tyrosine kinase (BTK), LFM-A13 [alpha-cyano-beta-hydroxy-beta-methyl-N-(2, 5-dibromophenyl)propenamide]. | 1999 | J. Biol. Chem. | pmid:10092645 |
| Matsuda S et al. | Differential activation of c-Jun NH2-terminal kinase and p38 pathways during FTY720-induced apoptosis of T lymphocytes that is suppressed by the extracellular signal-regulated kinase pathway. | 1999 | J. Immunol. | pmid:10092785 |
| MacPhee I and Barker PA | Extended ceramide exposure activates the trkA receptor by increasing receptor homodimer formation. | 1999 | J. Neurochem. | pmid:10098845 |
| Blázquez C et al. | The stimulation of ketogenesis by cannabinoids in cultured astrocytes defines carnitine palmitoyltransferase I as a new ceramide-activated enzyme. | 1999 | J. Neurochem. | pmid:10098887 |
| Sweeney EA and Igarashi Y | Increases in ceramide levels in normal human mesangial cells subjected to different cellular stresses result from changes in distinct enzyme activities and can influence cellular responses to other stimuli. | 1999 | J. Biochem. | pmid:10101287 |
| Puranam KL et al. | CLN3 defines a novel antiapoptotic pathway operative in neurodegeneration and mediated by ceramide. | 1999 | Mol. Genet. Metab. | pmid:10191118 |
| Li S et al. | New methods for determining the enantiomeric purity of erythro -sphingosine. | 1999 | J. Lipid Res. | pmid:10191301 |
| Liu CH et al. | Ligand-induced trafficking of the sphingosine-1-phosphate receptor EDG-1. | 1999 | Mol. Biol. Cell | pmid:10198065 |
| Tolleson WH et al. | Fumonisin B1 induces apoptosis in cultured human keratinocytes through sphinganine accumulation and ceramide depletion. | 1999 | Int. J. Oncol. | pmid:10200332 |
| Alesse E et al. | The growth arrest and downregulation of c-myc transcription induced by ceramide are related events dependent on p21 induction, Rb underphosphorylation and E2F sequestering. | 1998 | Cell Death Differ. | pmid:10200487 |
| Padrón JM et al. | Synthesis, in vitro cytotoxicity and in vivo anti-inflammatory activity of long chain 3-amino-1,2-diols. | 1999 | Bioorg. Med. Chem. Lett. | pmid:10206543 |
| Calcerrada MC et al. | Sphingosylphosphorylcholine increases calcium concentration in isolated brain nuclei. | 1999 | Neurosci. Res. | pmid:10211767 |
| Zhang Q et al. | Sphingosine 1-phosphate stimulates fibronectin matrix assembly through a Rho-dependent signal pathway. | 1999 | Blood | pmid:10216094 |
| Lee BR and Um HD | Hydrogen peroxide suppresses U937 cell death by two different mechanisms depending on its concentration. | 1999 | Exp. Cell Res. | pmid:10222135 |
| Herr I et al. | FK506 prevents stroke-induced generation of ceramide and apoptosis signaling. | 1999 | Brain Res. | pmid:10224298 |
| Watton SJ and Downward J | Akt/PKB localisation and 3' phosphoinositide generation at sites of epithelial cell-matrix and cell-cell interaction. | 1999 | Curr. Biol. | pmid:10226029 |
| Mengubas K et al. | Ceramide-induced killing of normal and malignant human lymphocytes is by a non-apoptotic mechanism. | 1999 | Oncogene | pmid:10229201 |
| Kim YH and Kim SS | Increase of MnSOD expression and decrease of JNK activity determine the TNF sensitivity in bcl2-transfected L929 cells. | 1999 | Cytokine | pmid:10328866 |
| Mengubas K et al. | Killing of T lymphocytes by synthetic ceramide is by a nonapoptotic mechanism and is abrogated following mitogenic activation. | 1999 | Exp. Cell Res. | pmid:10328959 |
| Nikmo A et al. | Sphingosylphosphorylcholine activates Gq, Gi-2, and Gi-3 in thyroid FRTL-5 cells: implications for the activation of calcium fluxes and Na+-H+ exchange. | 1999 | Biochem. Biophys. Res. Commun. | pmid:10329469 |
| Gottlieb D et al. | The DPL1 gene is involved in mediating the response to nutrient deprivation in Saccharomyces cerevisiae. | 1999 | Mol. Cell Biol. Res. Commun. | pmid:10329480 |
| Huang JS et al. | Ethanol potentiates the mitogenic effects of sphingosine 1-phosphate by a zinc- and calcium-dependent mechanism in fibroblasts. | 1999 | Arch. Biochem. Biophys. | pmid:10334873 |
| Chen N et al. | Translocation of protein kinase Cepsilon and protein kinase Cdelta to membrane is required for ultraviolet B-induced activation of mitogen-activated protein kinases and apoptosis. | 1999 | J. Biol. Chem. | pmid:10336426 |
| Cain BS et al. | Therapeutic strategies to reduce TNF-alpha mediated cardiac contractile depression following ischemia and reperfusion. | 1999 | J. Mol. Cell. Cardiol. | pmid:10336835 |
| Piperno M et al. | Osteoarthritic cartilage fibrillation is associated with a decrease in chondrocyte adhesion to fibronectin. | 1998 | Osteoarthr. Cartil. | pmid:10343772 |
| Taniwaki T et al. | Ceramide induces apoptosis to immature cerebellar granule cells in culture. | 1999 | Neurochem. Res. | pmid:10344598 |
| Wang JD et al. | Early induction of apoptosis in androgen-independent prostate cancer cell line by FTY720 requires caspase-3 activation. | 1999 | Prostate | pmid:10344723 |
| Masamune A et al. | Helicobacter pylori-dependent ceramide production may mediate increased interleukin 8 expression in human gastric cancer cell lines. | 1999 | Gastroenterology | pmid:10348816 |
| Goetzl EJ et al. | Lysophospholipid enhancement of human T cell sensitivity to diphtheria toxin by increased expression of heparin-binding epidermal growth factor. | 1999 May-Jun | Proc. Assoc. Am. Physicians | pmid:10354366 |
| Pruschy M et al. | Ceramide triggers p53-dependent apoptosis in genetically defined fibrosarcoma tumour cells. | 1999 | Br. J. Cancer | pmid:10360645 |
| Hisano N et al. | Induction and suppression of endothelial cell apoptosis by sphingolipids: a possible in vitro model for cell-cell interactions between platelets and endothelial cells. | 1999 | Blood | pmid:10361127 |
| Watanabe H et al. | Effect of a new immunosuppressant, FTY720, on joint allografts. | 1999 | J Reconstr Microsurg | pmid:10363553 |
| Dickson RC and Lester RL | Metabolism and selected functions of sphingolipids in the yeast Saccharomyces cerevisiae. | 1999 | Biochim. Biophys. Acta | pmid:10366774 |
| Zdebska E and Kościelak J | Studies on the structure and I-blood-group activity of poly(glycosyl)ceramides. | 1978 | Eur. J. Biochem. | pmid:103710 |
| Li PL et al. | Effect of ceramide on KCa channel activity and vascular tone in coronary arteries. | 1999 | Hypertension | pmid:10373230 |
| Stewart CE et al. | Increased, not decreased activation of the insulin-like growth factor (IGF) receptor signalling pathway during ceramide-induced apoptosis. | 1999 | Growth Horm. IGF Res. | pmid:10373346 |
| Meacci E et al. | Effect of Rho and ADP-ribosylation factor GTPases on phospholipase D activity in intact human adenocarcinoma A549 cells. | 1999 | J. Biol. Chem. | pmid:10373471 |
| Tolan D et al. | Assessment of the extracellular and intracellular actions of sphingosine 1-phosphate by using the p42/p44 mitogen-activated protein kinase cascade as a model. | 1999 | Cell. Signal. | pmid:10376808 |
| Okamoto H et al. | EDG3 is a functional receptor specific for sphingosine 1-phosphate and sphingosylphosphorylcholine with signaling characteristics distinct from EDG1 and AGR16. | 1999 | Biochem. Biophys. Res. Commun. | pmid:10381367 |
| Jones BE et al. | Ceramide induces caspase-independent apoptosis in rat hepatocytes sensitized by inhibition of RNA synthesis. | 1999 | Hepatology | pmid:10385659 |
| Gueguen G et al. | Structure-activity analysis of the effects of lysophosphatidic acid on platelet aggregation. | 1999 | Biochemistry | pmid:10387090 |
| Dallalio G et al. | Inhibition of human erythroid colony formation by ceramide. | 1999 | Exp. Hematol. | pmid:10390188 |
| Yang L et al. | Sphingosine 1-phosphate formation and intracellular Ca2+ mobilization in human platelets: evaluation with sphingosine kinase inhibitors. | 1999 | J. Biochem. | pmid:10393324 |
| Payne SG et al. | Epidermal growth factor inhibits ceramide-induced apoptosis and lowers ceramide levels in primary placental trophoblasts. | 1999 | J. Cell. Physiol. | pmid:10395296 |
| Ghidoni R et al. | Use of sphingolipid analogs: benefits and risks. | 1999 | Biochim. Biophys. Acta | pmid:10395962 |
| Shinoda J et al. | Effect of ceramide on interleukin-6 synthesis in osteoblast-like cells. | 1999 | Cell. Signal. | pmid:10400316 |
| Yoon HT et al. | Improved fluorescent determination method of cellular sphingoid bases in high-performance liquid chromatography. | 1999 | Arch. Pharm. Res. | pmid:10403133 |
| Czajkowski R and Barańska J | Sphingosine and phorbol ester modulate protein kinase C activity and modify ATP-evoked calcium mobilization in glioma C6 cells. | 1999 | Biochem. Biophys. Res. Commun. | pmid:10403815 |
| Buisson-Legendre N et al. | Involvement of the 92-kDa gelatinase (matrix metalloproteinase-9) in the ceramide-mediated inhibition of human keratinocyte growth. | 1999 | Biochem. Biophys. Res. Commun. | pmid:10403818 |
| Gijsbers S et al. | N-acetyl-sphingenine-1-phosphate is a potent calcium mobilizing agent. | 1999 | FEBS Lett. | pmid:10405158 |
| Edsall LC and Spiegel S | Enzymatic measurement of sphingosine 1-phosphate. | 1999 | Anal. Biochem. | pmid:10405296 |
| Stewart CE et al. | Increased tyrosine kinase activity but not calcium mobilization is required for ceramide-induced apoptosis. | 1999 | Exp. Cell Res. | pmid:10413587 |
| Kozawa O et al. | Sphingosine 1-phosphate regulates heat shock protein 27 induction by a p38 MAP kinase-dependent mechanism in aortic smooth muscle cells. | 1999 | Exp. Cell Res. | pmid:10413591 |
| Turner PC et al. | Fumonisin contamination of food: progress in development of biomarkers to better assess human health risks. | 1999 | Mutat. Res. | pmid:10415433 |
| Alessenko AV and Khrenov AV | Role of sphingosine in induced apoptosis. | 1999 | Lipids | pmid:10419095 |
| Brindley DN et al. | Tumor necrosis factor-alpha and ceramides in insulin resistance. | 1999 | Lipids | pmid:10419100 |
| Augé N et al. | Role of sphingosine 1-phosphate in the mitogenesis induced by oxidized low density lipoprotein in smooth muscle cells via activation of sphingomyelinase, ceramidase, and sphingosine kinase. | 1999 | J. Biol. Chem. | pmid:10419457 |
| Hla T et al. | Sphingosine-1-phosphate: extracellular mediator or intracellular second messenger? | 1999 | Biochem. Pharmacol. | pmid:10423159 |
| Sugishita K et al. | Cellular basis for the acute inhibitory effects of IL-6 and TNF- alpha on excitation-contraction coupling. | 1999 | J. Mol. Cell. Cardiol. | pmid:10423344 |
| Tsugane K et al. | A possible role of nuclear ceramide and sphingosine in hepatocyte apoptosis in rat liver. | 1999 | J. Hepatol. | pmid:10424278 |
| Pahan K et al. | Induction of the manganese superoxide dismutase gene by sphingomyelinase and ceramide. | 1999 | J. Neurochem. | pmid:10428046 |
| Yoshimura S et al. | Inhibition of neutral sphingomyelinase activation and ceramide formation by glutathione in hypoxic PC12 cell death. | 1999 | J. Neurochem. | pmid:10428064 |
| Luo ZJ et al. | Analysis of the mode of action of a novel immunosuppressant FTY720 in mice. | 1999 | Immunopharmacology | pmid:10428648 |
| Scaffidi C et al. | Differential modulation of apoptosis sensitivity in CD95 type I and type II cells. | 1999 | J. Biol. Chem. | pmid:10428830 |
| Stewart ME and Downing DT | A new 6-hydroxy-4-sphingenine-containing ceramide in human skin. | 1999 | J. Lipid Res. | pmid:10428979 |
| Coka-Guevara S et al. | Adenosine inhibits the renal plasma-membrane (Ca2+ + Mg2+)-ATPase through a pathway sensitive to cholera toxin and sphingosine. | 1999 | Eur. J. Biochem. | pmid:10429189 |
| Prieschl EE et al. | The balance between sphingosine and sphingosine-1-phosphate is decisive for mast cell activation after Fc epsilon receptor I triggering. | 1999 | J. Exp. Med. | pmid:10429665 |
| Viani P et al. | Sphingosine inhibits nitric oxide synthase from cerebellar granule cells differentiated in vitro. | 1999 | FEBS Lett. | pmid:10431831 |
| Hotchin NA et al. | Differential activation of focal adhesion kinase, Rho and Rac by the ninth and tenth FIII domains of fibronectin. | 1999 | J. Cell. Sci. | pmid:10444388 |
| Cain BS et al. | Tumor necrosis factor-alpha and interleukin-1beta synergistically depress human myocardial function. | 1999 | Crit. Care Med. | pmid:10446825 |
| Kumar A et al. | Cytokines and septic myocardial depression: nitric oxide versus sphingosine/ceramide? | 1999 | Crit. Care Med. | pmid:10446843 |
| Vartanian A et al. | Ap4A induces apoptosis in human cultured cells. | 1999 | FEBS Lett. | pmid:10452553 |
| Dygas A et al. | Exogenous sphingosine 1-phosphate and sphingosylphosphorylcholine do not stimulate phospholipase D in C6 glioma cells. | 1999 | Acta Biochim. Pol. | pmid:10453985 |
| Wójcik M and Barańska J | Sphingosine, sphingosylphosphorylcholine and sphingosine 1-phosphate modulate phosphatidylserine homeostasis in glioma C6 cells. | 1999 | Acta Biochim. Pol. | pmid:10453988 |
| Hida H et al. | Regulation of mitogen-activated protein kinases by sphingolipid products in oligodendrocytes. | 1999 | J. Neurosci. | pmid:10460252 |
| Waeber C and Chiu ML | In vitro autoradiographic visualization of guanosine-5'-O-(3-[35S]thio)triphosphate binding stimulated by sphingosine 1-phosphate and lysophosphatidic acid. | 1999 | J. Neurochem. | pmid:10461914 |
| Malaquias AT and Oliveira MM | Phospholipid signalling pathways in Trypanosoma cruzi growth control. | 1999 | Acta Trop. | pmid:10465050 |
| Maile LA et al. | The role of cell surface attachment and proteolysis in the insulin-like growth factor (IGF)-independent effects of IGF-binding protein-3 on apoptosis in breast epithelial cells. | 1999 | Endocrinology | pmid:10465274 |
| Tedesco MM and Matile S | Spectroscopic detection of endovesiculation by large unilamellar phosphatidylcholine vesicles: effects of chlorpromazine, dibucaine, and safingol. | 1999 | Bioorg. Med. Chem. | pmid:10465411 |
| Ramstedt B and Slotte JP | Comparison of the biophysical properties of racemic and d-erythro-N-acyl sphingomyelins. | 1999 | Biophys. J. | pmid:10465760 |
| Belaud-Rotureau MA et al. | Ceramide-induced apoptosis occurs independently of caspases and is decreased by leupeptin. | 1999 | Cell Death Differ. | pmid:10467353 |
sphingosine
sphingosine is a lipid of Sphingolipids (SP) class.
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