| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Van Brocklyn JR et al. | Sphingosine 1-phosphate-induced cell rounding and neurite retraction are mediated by the G protein-coupled receptor H218. | 1999 | J. Biol. Chem. | pmid:9988698 |
| Roze LV and Linz JE | Lovastatin triggers an apoptosis-like cell death process in the fungus Mucor racemosus. | 1998 | Fungal Genet. Biol. | pmid:9974223 |
| Goetzl EJ et al. | Lysophosphatidic acid and sphingosine 1-phosphate protection of T cells from apoptosis in association with suppression of Bax. | 1999 | J. Immunol. | pmid:9973477 |
| Skrzypek MS et al. | Analysis of phosphorylated sphingolipid long-chain bases reveals potential roles in heat stress and growth control in Saccharomyces. | 1999 | J. Bacteriol. | pmid:9973338 |
| Rodriguez-Lafrasse C and Vanier MT | Sphingosylphosphorylcholine in Niemann-Pick disease brain: accumulation in type A but not in type B. | 1999 | Neurochem. Res. | pmid:9972865 |
| Alemany R et al. | Formyl peptide receptor signaling in HL-60 cells through sphingosine kinase. | 1999 | J. Biol. Chem. | pmid:9933590 |
| Yohe HC et al. | C20-sphingosine as a determining factor in aggregation of gangliosides. | 1976 | J. Biol. Chem. | pmid:993205 |
| Zhang G et al. | Comparative analysis of three murine G-protein coupled receptors activated by sphingosine-1-phosphate. | 1999 | Gene | pmid:9931453 |
| Hung WC et al. | Activation of caspase-3-like proteases in apoptosis induced by sphingosine and other long-chain bases in Hep3B hepatoma cells. | 1999 | Biochem. J. | pmid:9931312 |
| Riboni L et al. | Predominance of the acylation route in the metabolic processing of exogenous sphingosine in neural and extraneural cells in culture. | 1999 | Biochem. J. | pmid:9931310 |
| Sato K et al. | Activation of phospholipase C-Ca2+ system by sphingosine 1-phosphate in CHO cells transfected with Edg-3, a putative lipid receptor. | 1999 | FEBS Lett. | pmid:9928946 |
| Centeno F et al. | Partial lithium-associated protection against apoptosis induced by C2-ceramide in cerebellar granule neurons. | 1998 | Neuroreport | pmid:9926873 |
| Kiuchi M et al. | Synthesis and biological evaluation of 2,2-disubstituted 2-aminoethanols: analogues of FTY720. | 1998 | Bioorg. Med. Chem. Lett. | pmid:9925439 |
| Orlati S et al. | Sphingosylphosphorylcholine and sphingosine-1-phosphate mobilize cytosolic calcium through different mechanisms in human airway epithelial cells. | 1998 | Cell Calcium | pmid:9924630 |
| Troncoso P et al. | Prophylaxis of acute renal allograft rejection using FTY720 in combination with subtherapeutic doses of cyclosporine. | 1999 | Transplantation | pmid:9921811 |
| Soboloff J et al. | Acyl chain length-specific ceramide-induced changes in intracellular Ca2+ concentration and progesterone production are not regulated by tumor necrosis factor alpha in hen granulosa cells. | 1999 | Biol. Reprod. | pmid:9915989 |
| Wang E et al. | Fumonisin B1 consumption by rats causes reversible, dose-dependent increases in urinary sphinganine and sphingosine. | 1999 | J. Nutr. | pmid:9915902 |
| Jennemann R et al. | Novel glycoinositolphosphosphingolipids, basidiolipids, from Agaricus. | 1999 | Eur. J. Biochem. | pmid:9914511 |
| Xu FY et al. | N-Acetylsphingosine stimulates phosphatidylglycerolphosphate synthase activity in H9c2 cardiac cells. | 1999 | Biochem. J. | pmid:9895291 |
| Yanagawa Y et al. | FTY720, a novel immunosuppressant, induces sequestration of circulating mature lymphocytes by acceleration of lymphocyte homing in rats, III. Increase in frequency of CD62L-positive T cells in Peyer's patches by FTY720-induced lymphocyte homing. | 1998 | Immunology | pmid:9893050 |
| Reiners JJ and Clift RE | Aryl hydrocarbon receptor regulation of ceramide-induced apoptosis in murine hepatoma 1c1c7 cells. A function independent of aryl hydrocarbon receptor nuclear translocator. | 1999 | J. Biol. Chem. | pmid:9891021 |
| Imokawa G et al. | Sphingosylphosphorylcholine is a potent inducer of intercellular adhesion molecule-1 expression in human keratinocytes. | 1999 | J. Invest. Dermatol. | pmid:9886270 |
| Raeder EM et al. | Sphingosine blocks human polymorphonuclear leukocyte phagocytosis through inhibition of mitogen-activated protein kinase activation. | 1999 | Blood | pmid:9885231 |
| Sato K et al. | Possible involvement of cell surface receptors in sphingosine 1-phosphate-induced activation of extracellular signal-regulated kinase in C6 glioma cells. | 1999 | Mol. Pharmacol. | pmid:9882706 |
| MacKichan ML and DeFranco AL | Role of ceramide in lipopolysaccharide (LPS)-induced signaling. LPS increases ceramide rather than acting as a structural homolog. | 1999 | J. Biol. Chem. | pmid:9880559 |
| Sato K et al. | Downregulation of mRNA expression of Edg-3, a putative sphingosine 1-phosphate receptor coupled to Ca2+ signaling, during differentiation of HL-60 leukemia cells. | 1998 | Biochem. Biophys. Res. Commun. | pmid:9878524 |
| Qiao L et al. | Synthesis and evaluation of a photolyzable derivative of sphingosine 1-phosphate--caged SPP. | 1998 | Bioorg. Med. Chem. Lett. | pmid:9871527 |
| Li S et al. | Chemical synthesis of D-ribo-phytosphingosine-1-phosphate, a potential modulator of cellular processes. | 1999 | J. Lipid Res. | pmid:9869657 |
| Miyata Y et al. | Prolongation of concordant xenograft survival by treatment with FTY720. | 1998 | Transplant. Proc. | pmid:9865334 |
| Scheid MP et al. | Ceramide and cyclic adenosine monophosphate (cAMP) induce cAMP response element binding protein phosphorylation via distinct signaling pathways while having opposite effects on myeloid cell survival. | 1999 | Blood | pmid:9864164 |
| Gumprecht LA et al. | Development of fumonisin-induced hepatotoxicity and pulmonary edema in orally dosed swine: morphological and biochemical alterations. | 1998 Nov-Dec | Toxicol Pathol | pmid:9864095 |
| Holopainen JM et al. | Sphingomyelinase induces lipid microdomain formation in a fluid phosphatidylcholine/sphingomyelin membrane. | 1998 | Biochemistry | pmid:9860872 |
| Bektas M et al. | Induction of apoptosis by synthetic ceramide analogues in the human keratinocyte cell line HaCaT. | 1998 | Exp. Dermatol. | pmid:9858137 |
| Gonda K et al. | The novel sphingosine 1-phosphate receptor AGR16 is coupled via pertussis toxin-sensitive and -insensitive G-proteins to multiple signalling pathways. | 1999 | Biochem. J. | pmid:9854026 |
| Zheng T et al. | C2-ceramide attenuates prostaglandin F2alpha-induced vasoconstriction and elevation of [Ca2+]i in canine cerebral vascular smooth muscle. | 1998 | Neurosci. Lett. | pmid:9853716 |
| Chen PF et al. | Ca2+ signaling induced by sphingosylphosphorylcholine and sphingosine 1-phosphate via distinct mechanisms in rat glomerular mesangial cells. | 1998 | Kidney Int. | pmid:9844123 |
| Abbas HK et al. | Phytotoxicity and cytotoxicity of the fumonisin C and P series of mycotoxins from Fusarium spp. fungi. | 1998 | Toxicon | pmid:9839687 |
| Abbas HK et al. | Ultrastructural effects of AAL-toxin TA from the fungus Alternaria alternata on black nightshade (Solanum nigrum L.) leaf discs and correlation with biochemical measures of toxicity. | 1998 | Toxicon | pmid:9839666 |
| Yan H et al. | Immunosuppressive effect of FTY 720 on autoimmune diabetes models. | 1998 | Transplant. Proc. | pmid:9838514 |
| Suzuki K et al. | Immunosuppressive effect of FTY 720 on rat pancreas allograft. | 1998 | Transplant. Proc. | pmid:9838506 |
| Xia P et al. | Tumor necrosis factor-alpha induces adhesion molecule expression through the sphingosine kinase pathway. | 1998 | Proc. Natl. Acad. Sci. U.S.A. | pmid:9826677 |
| Guo C et al. | Differential stimulation of proline-rich tyrosine kinase 2 and mitogen-activated protein kinase by sphingosine 1-phosphate. | 1998 | Eur. J. Biochem. | pmid:9826186 |
| Grosman N | Influence of probes for calcium-calmodulin and protein kinase C signalling on the plasma membrane Ca2+-ATPase activity of rat synaptosomes and leukocyte membranes. | 1998 | Immunopharmacology | pmid:9826030 |
| Soeda S et al. | Tumor necrosis factor-alpha-induced release of plasminogen activator inhibitor-1 from human umbilical vein endothelial cells: involvement of intracellular ceramide signaling event. | 1998 | Biochim. Biophys. Acta | pmid:9824663 |
| Nyberg L et al. | Digestion of ceramide by human milk bile salt-stimulated lipase. | 1998 | J. Pediatr. Gastroenterol. Nutr. | pmid:9822324 |
| Chigorno V et al. | Human fibroblasts in culture metabolize differently exogenous G(M3) ganglioside species containing C18 and C20 sphingosine. | 1998 | Acta Biochim. Pol. | pmid:9821869 |
| Ayar A et al. | Mobilization of intracellular calcium by intracellular flash photolysis of caged dihydrosphingosine in cultured neonatal rat sensory neurones. | 1998 | Acta Biochim. Pol. | pmid:9821863 |
| Igarashi Y and Yatomi Y | Sphingosine 1-phosphate is a blood constituent released from activated platelets, possibly playing a variety of physiological and pathophysiological roles. | 1998 | Acta Biochim. Pol. | pmid:9821862 |
| Yorek MA et al. | Opposing effects of tumour necrosis factor alpha and hyperosmolarity on Na+/myo-inositol co-transporter mRNA levels and myo-inositol accumulation by 3T3-L1 adipocytes. | 1998 | Biochem. J. | pmid:9820807 |
| Schwartz GK et al. | A pilot clinical/pharmacological study of the protein kinase C-specific inhibitor safingol alone and in combination with doxorubicin. | 1997 | Clin. Cancer Res. | pmid:9815717 |
| Shirahama T et al. | In vitro and in vivo induction of apoptosis by sphingosine and N, N-dimethylsphingosine in human epidermoid carcinoma KB-3-1 and its multidrug-resistant cells. | 1997 | Clin. Cancer Res. | pmid:9815681 |
| Cartus T et al. | Distribution of protein phosphatases type 1 and 2A in RINm5F cells. | 1998 | Regul. Pept. | pmid:9809799 |
| Reggiori F and Conzelmann A | Biosynthesis of inositol phosphoceramides and remodeling of glycosylphosphatidylinositol anchors in Saccharomyces cerevisiae are mediated by different enzymes. | 1998 | J. Biol. Chem. | pmid:9804825 |
| Jarvis WD et al. | Evidence for involvement of mitogen-activated protein kinase, rather than stress-activated protein kinase, in potentiation of 1-beta-D-arabinofuranosylcytosine-induced apoptosis by interruption of protein kinase C signaling. | 1998 | Mol. Pharmacol. | pmid:9804619 |
| Sánchez C et al. | Involvement of sphingomyelin hydrolysis and the mitogen-activated protein kinase cascade in the Delta9-tetrahydrocannabinol-induced stimulation of glucose metabolism in primary astrocytes. | 1998 | Mol. Pharmacol. | pmid:9804618 |
| Ji L et al. | Effects of endoglycoceramidase or D-threo-1-phenyl-2-decanoylamino-3-morpholino-1-propanol on glucose uptake, glycolysis, and mitochondrial respiration in HL60 cells. | 1998 | Arch. Biochem. Biophys. | pmid:9799567 |
| Mizushima N et al. | Ceramide, a mediator of interleukin 1, tumour necrosis factor alpha, as well as Fas receptor signalling, induces apoptosis of rheumatoid arthritis synovial cells. | 1998 | Ann. Rheum. Dis. | pmid:9797556 |
| Riboni L et al. | The effects of exogenous sphingosine on Neuro2a cells are strictly related to the overall capacity of cells to metabolize sphingosine. | 1998 | J. Biochem. | pmid:9792911 |
| Ping SE and Barrett GL | Ceramide can induce cell death in sensory neurons, whereas ceramide analogues and sphingosine promote survival. | 1998 | J. Neurosci. Res. | pmid:9788279 |
| Yano M et al. | Quantitative analysis of ceramide molecular species by high performance liquid chromatography. | 1998 | J. Lipid Res. | pmid:9788256 |
| Hida H et al. | Ceramide inhibits inwardly rectifying K+ currents via a Ras- and Raf-1-dependent pathway in cultured oligodendrocytes. | 1998 | J. Neurosci. | pmid:9786978 |
| Klostergaard J et al. | Characterization of cytotoxicity induced by sphingolipids in multidrug-resistant leukemia cells. | 1998 | Leuk. Res. | pmid:9783808 |
| Lian JP et al. | Products of sphingolipid catabolism block activation of the p21-activated protein kinases in neutrophils. | 1998 | J. Immunol. | pmid:9780215 |
| Birt DF et al. | Inhibition of skin carcinomas but not papillomas by sphingosine, N-methylsphingosine, and N-acetylsphingosine. | 1998 | Nutr Cancer | pmid:9770723 |
| Shimizu C et al. | A novel immunosuppressant, FTY720, increases the efficiency of a superantigen-induced peripheral T-cell deletion whilst inhibiting negative selection in the thymus. | 1998 | Immunology | pmid:9767438 |
| Vasta V et al. | Effects of sphingosine 1-phosphate and bradykinin on phospholipid signalling in human epithelial A549 cells. | 1998 | Biochem. Soc. Trans. | pmid:9765948 |
| Escargueil-Blanc I et al. | Apoptosis and activation of the sphingomyelin-ceramide pathway induced by oxidized low density lipoproteins are not causally related in ECV-304 endothelial cells. | 1998 | J. Biol. Chem. | pmid:9765267 |
| Okamoto H et al. | EDG1 is a functional sphingosine-1-phosphate receptor that is linked via a Gi/o to multiple signaling pathways, including phospholipase C activation, Ca2+ mobilization, Ras-mitogen-activated protein kinase activation, and adenylate cyclase inhibition. | 1998 | J. Biol. Chem. | pmid:9765227 |
| Banno Y et al. | Evidence for the presence of multiple forms of Sph kinase in human platelets. | 1998 | Biochem. J. | pmid:9761727 |
| Kimura M and Ogihara M | Effects of insulin-like growth factor I and II on DNA synthesis and proliferation in primary cultures of adult rat hepatocytes. | 1998 | Eur. J. Pharmacol. | pmid:9754929 |
| Sakaguchi M et al. | Cytokine production by T cells infiltrating in the eye of uveitis patients. | 1998 Jul-Aug | Jpn. J. Ophthalmol. | pmid:9749865 |
| Mutoh T et al. | Glucosylceramide synthase inhibitor inhibits the action of nerve growth factor in PC12 cells. | 1998 | J. Biol. Chem. | pmid:9748278 |
| Vento R et al. | Induction of programmed cell death in human retinoblastoma Y79 cells by C2-ceramide. | 1998 | Mol. Cell. Biochem. | pmid:9746206 |
| Asfaw B et al. | Degradation of blood group A glycolipid A-6-2 by normal and mutant human skin fibroblasts. | 1998 | J. Lipid Res. | pmid:9741689 |
| Ghahremani M et al. | Activation of Fas ligand/receptor system kills ovarian cancer cell lines by an apoptotic mechanism. | 1998 | Gynecol. Oncol. | pmid:9740705 |
| Mathes C et al. | Calcium release-activated calcium current (ICRAC) is a direct target for sphingosine. | 1998 | J. Biol. Chem. | pmid:9737958 |
| Edsall LC et al. | N,N-Dimethylsphingosine is a potent competitive inhibitor of sphingosine kinase but not of protein kinase C: modulation of cellular levels of sphingosine 1-phosphate and ceramide. | 1998 | Biochemistry | pmid:9737868 |
| Ciacci-Zanella JR et al. | Characterization of cell-cycle arrest by fumonisin B1 in CV-1 cells. | 1998 Sep-Oct | Food Chem. Toxicol. | pmid:9737426 |
| Bodennec J et al. | Phytosphingosine biosynthesis differs from sphingosine in fish leukocytes and involves a transfer of methyl groups from [3H-methyl]methionine precursor. | 1998 | Biochem. Biophys. Res. Commun. | pmid:9735337 |
| Orlati S et al. | Intracellular calcium mobilization and phospholipid degradation in sphingosylphosphorylcholine-stimulated human airway epithelial cells. | 1998 | Biochem. J. | pmid:9729473 |
| Zager RA et al. | Ceramide accumulation during oxidant renal tubular injury: mechanisms and potential consequences. | 1998 | J. Am. Soc. Nephrol. | pmid:9727376 |
| Meyer zu Heringdorf D et al. | Discrimination between plasma membrane and intracellular target sites of sphingosylphosphorylcholine. | 1998 | Eur. J. Pharmacol. | pmid:9726638 |
| Hama-Inaba H et al. | Radio-sensitive murine thymoma cell line 3SB: characterization of its apoptosis-resistant variants induced by repeated X-irradiation. | 1998 | Mutat. Res. | pmid:9726009 |
| Lakics V and Vogel SN | Lipopolysaccharide and ceramide use divergent signaling pathways to induce cell death in murine macrophages. | 1998 | J. Immunol. | pmid:9725248 |
| Matsuda T et al. | Caspase requirement for the apoptotic death of WR19L-induced by FTY720. | 1998 | Transplant. Proc. | pmid:9723502 |
| Xu M et al. | FTY720 compares with FK 506 as rescue therapy in rat heterotopic cardiac transplantation. | 1998 | Transplant. Proc. | pmid:9723447 |
| Nakajima H et al. | FTY720 inhibits the mRNA expression of intragraft cytotoxic molecules, leading to cardiac allograft survival. | 1998 | Transplant. Proc. | pmid:9723446 |
| Stepkowski SM et al. | Synergistic interaction of FTY720 with cyclosporine or sirolimus to prolong heart allograft survival. | 1998 | Transplant. Proc. | pmid:9723445 |
| Kahan BD | FTY720: a new immunosuppressive agent with novel mechanism(s) of action. | 1998 | Transplant. Proc. | pmid:9723444 |
| van Echten-Deckert G et al. | Phosphorylated cis-4-methylsphingosine mimics the mitogenic effect of sphingosine-1-phosphate in Swiss 3T3 fibroblasts. | 1998 | J. Biol. Chem. | pmid:9722598 |
| Patel M | Inhibition of neuronal apoptosis by a metalloporphyrin superoxide dismutase mimic. | 1998 | J. Neurochem. | pmid:9721731 |
| Troncoso P and Kahan BD | Preclinical evaluation of a new immunosuppressive agent, FTY720. | 1998 | Clin. Biochem. | pmid:9721436 |
| Zhang J et al. | Regulation of membrane release in apoptosis. | 1998 | Biochem. J. | pmid:9716508 |
| Summers SA et al. | Regulation of insulin-stimulated glucose transporter GLUT4 translocation and Akt kinase activity by ceramide. | 1998 | Mol. Cell. Biol. | pmid:9710629 |
| Yamasaki T et al. | Effect of a new immunosuppressive agent, FTY720, on survival of islet allografts. | Cell Transplant | pmid:9710310 | |
| Roberts R et al. | Human type 2 phosphatidic acid phosphohydrolases. Substrate specificity of the type 2a, 2b, and 2c enzymes and cell surface activity of the 2a isoform. | 1998 | J. Biol. Chem. | pmid:9705349 |
| Megidish T et al. | A novel sphingosine-dependent protein kinase (SDK1) specifically phosphorylates certain isoforms of 14-3-3 protein. | 1998 | J. Biol. Chem. | pmid:9705322 |
| Xu M et al. | Effect of peritransplant FTY720 alone or in combination with post-transplant tacrolimus in a rat model of cardiac allotransplantation. | 1998 | Transpl. Int. | pmid:9704394 |
| Cha SH et al. | Effect of silica on phospholipase D activity in rat alveolar macrophages. | 1998 | Ind Health | pmid:9701905 |
| Galadari S et al. | Purification and characterization of ceramide-activated protein phosphatases. | 1998 | Biochemistry | pmid:9698369 |
sphingosine
sphingosine is a lipid of Sphingolipids (SP) class.
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