| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Tang HB et al. | S1P/S1PR3 signaling mediated proliferation of pericytes via Ras/pERK pathway and CAY10444 had beneficial effects on spinal cord injury. | 2018 | Biochem. Biophys. Res. Commun. | pmid:29534963 |
| Yu FC et al. | Protective effect of sphingosine-1-phosphate for chronic intermittent hypoxia-induced endothelial cell injury. | 2018 | Biochem. Biophys. Res. Commun. | pmid:29550481 |
| Nádró B et al. | [The role of apolipoprotein M and sphingosine 1-phosphate axis in the prevention of atherosclerosis]. | 2018 | Orv Hetil | pmid:29376427 |
| Deshpande GP et al. | Sphingosine-1-phosphate (S1P) activates STAT3 to protect against de novo acute heart failure (AHF). | 2018 | Life Sci. | pmid:29373815 |
| Książek M et al. | Arteriovenous Sphingosine-1-Phosphate Differences Across Selected Organs of the Rat. | 2018 | Cell. Physiol. Biochem. | pmid:29316552 |
| Huang Y et al. | S1P-dependent interorgan trafficking of group 2 innate lymphoid cells supports host defense. | 2018 | Science | pmid:29302015 |
| Ahn EH et al. | Sphingosine Induces Apoptosis and Down-regulation of in PAX3-FOXO1-positive Alveolar Rhabdomyosarcoma Cells Irrespective of Mutation. | 2018 | Anticancer Res. | pmid:29277758 |
| Zhang YL et al. | Non-invasive assessment of culture media from goat cloned embryos associated with subjective morphology by gas chromatography - mass spectroscopy-based metabolomic analysis. | 2018 | Anim. Sci. J. | pmid:28833899 |
| Zheng Y et al. | A Sphingosine-type cerebroside in Clavicorona pyxidata induce fruit body formation. | 2018 | Nat. Prod. Res. | pmid:28347179 |
| Ogretmen B | Sphingolipid metabolism in cancer signalling and therapy. | 2018 | Nat. Rev. Cancer | pmid:29147025 |
| van der Weyden L et al. | Genome-wide in vivo screen identifies novel host regulators of metastatic colonization. | 2017 | Nature | pmid:28052056 |
| Lima S et al. | Sphingosine and Sphingosine Kinase 1 Involvement in Endocytic Membrane Trafficking. | 2017 | J. Biol. Chem. | pmid:28049734 |
| Ogle ME et al. | Sphingosine-1-Phosphate Receptor-3 Supports Hematopoietic Stem and Progenitor Cell Residence Within the Bone Marrow Niche. | 2017 | Stem Cells | pmid:28026131 |
| Yung BS et al. | Selective coupling of the S1P receptor subtype to S1P-mediated RhoA activation and cardioprotection. | 2017 | J. Mol. Cell. Cardiol. | pmid:28017639 |
| Contaifer D et al. | Unsupervised analysis of combined lipid and coagulation data reveals coagulopathy subtypes among dialysis patients. | 2017 | J. Lipid Res. | pmid:27993949 |
| Myśliwiec H et al. | Increase in circulating sphingosine-1-phosphate and decrease in ceramide levels in psoriatic patients. | 2017 | Arch. Dermatol. Res. | pmid:27988894 |
| Frias MA et al. | High-density lipoprotein-associated sphingosine-1-phosphate activity in heterozygous familial hypercholesterolaemia. | 2017 | Eur. J. Clin. Invest. | pmid:27861771 |
| Fang V et al. | Gradients of the signaling lipid S1P in lymph nodes position natural killer cells and regulate their interferon-γ response. | 2017 | Nat. Immunol. | pmid:27841869 |
| Wang R et al. | Hepatic Stellate Cell Selective Disruption of Dynamin-2 GTPase Increases Murine Fibrogenesis through Up-Regulation of Sphingosine-1 Phosphate-Induced Cell Migration. | 2017 | Am. J. Pathol. | pmid:27840081 |
| O'Sullivan S and Dev KK | Sphingosine-1-phosphate receptor therapies: Advances in clinical trials for CNS-related diseases. | 2017 | Neuropharmacology | pmid:27825807 |
| Yanagida K and Hla T | Vascular and Immunobiology of the Circulatory Sphingosine 1-Phosphate Gradient. | 2017 | Annu. Rev. Physiol. | pmid:27813829 |
| Pal SK et al. | A phase 2 study of the sphingosine-1-phosphate antibody sonepcizumab in patients with metastatic renal cell carcinoma. | 2017 | Cancer | pmid:27727447 |
| Åukomska A et al. | The effect of low levels of lead (Pb) in the blood on levels of sphingosine-1-phosphate (S1P) and expression of S1P receptor 1 in the brain of the rat in the perinatal period. | 2017 | Chemosphere | pmid:27697711 |
| Sánchez DI et al. | Melatonin prevents deregulation of the sphingosine kinase/sphingosine 1-phosphate signaling pathway in a mouse model of diethylnitrosamine-induced hepatocellular carcinoma. | 2017 | J. Pineal Res. | pmid:27696512 |
| Katsuta E et al. | Doxorubicin effect is enhanced by sphingosine-1-phosphate signaling antagonist in breast cancer. | 2017 | J. Surg. Res. | pmid:29078883 |
| Vogt D and Stark H | Therapeutic Strategies and Pharmacological Tools Influencing S1P Signaling and Metabolism. | 2017 | Med Res Rev | pmid:27480072 |
| Yang J et al. | C2-ceramide influences alveolar epithelial barrier function by downregulating Zo-1, occludin and claudin-4 expression. | 2017 | Toxicol. Mech. Methods | pmid:28052715 |
| Khodorova A et al. | The TrkA receptor mediates experimental thermal hyperalgesia produced by nerve growth factor: Modulation by the p75 neurotrophin receptor. | 2017 | Neuroscience | pmid:27826102 |
| Mendelson K et al. | The ceramide synthase 2b gene mediates genomic sensing and regulation of sphingosine levels during zebrafish embryogenesis. | 2017 | Elife | pmid:28956531 |
| Baek S et al. | DJ-1 Regulates Differentiation of Human Mesenchymal Stem Cells into Smooth Muscle-like Cells in Response to Sphingosylphosphorylcholine. | 2017 | Proteomics | pmid:28949093 |
| Smith P et al. | Sphingosine 1-Phosphate Signaling and Its Pharmacological Modulation in Allogeneic Hematopoietic Stem Cell Transplantation. | 2017 | Int J Mol Sci | pmid:28934113 |
| Jiang R et al. | Protein kinase Cα stimulates hypoxia‑induced pulmonary artery smooth muscle cell proliferation in rats through activating the extracellular signal‑regulated kinase 1/2 pathway. | 2017 | Mol Med Rep | pmid:28901444 |
| Anjum I et al. | Enhancement of S1P-induced contractile response in detrusor smooth muscle of rats having cystitis. | 2017 | Eur. J. Pharmacol. | pmid:28882559 |
| Pierucci F et al. | Non-dioxin-like organic toxicant PCB153 modulates sphingolipid metabolism in liver progenitor cells: its role in Cx43-formed gap junction impairment. | 2017 | Arch. Toxicol. | pmid:27318803 |
| Haddadi N et al. | "Dicing and Splicing" Sphingosine Kinase and Relevance to Cancer. | 2017 | Int J Mol Sci | pmid:28869494 |
| Bosteen MH et al. | Effects of apolipoprotein M in uremic atherosclerosis. | 2017 | Atherosclerosis | pmid:28866363 |
| Della Sala G et al. | Zeamide, a Glycosylinositol Phosphorylceramide with the Novel Core Arap(1β→6)Ins Motif from the Marine Sponge Svenzea zeai. | 2017 | Molecules | pmid:28862696 |
| Choi MK et al. | Pharmacokinetics of Jaspine B and Enhancement of Intestinal Absorption of Jaspine B in the Presence of Bile Acid in Rats. | 2017 | Mar Drugs | pmid:28862650 |
| Olesch C et al. | Beyond Immune Cell Migration: The Emerging Role of the Sphingosine-1-phosphate Receptor S1PR4 as a Modulator of Innate Immune Cell Activation. | 2017 | Mediators Inflamm. | pmid:28848247 |
| Wang H et al. | Acetylation of Microcrystalline Cellulose by Transesterification in AmimCl/DMSO Cosolvent System. | 2017 | Molecules | pmid:28846619 |
| Leo A et al. | The Sphingosine 1-Phosphate Signaling Pathway in Epilepsy: A Possible Role for the Immunomodulator Drug Fingolimod in Epilepsy Treatment. | 2017 | CNS Neurol Disord Drug Targets | pmid:27823573 |
| Xiao W et al. | Fingolimod Suppresses a Cascade of Core Vicious Cycle in Dry Eye NOD Mouse Model: Involvement of Sphingosine-1-Phosphate Receptors in Infiltrating Leukocytes. | 2017 | Invest. Ophthalmol. Vis. Sci. | pmid:29214311 |
| Roch L et al. | High-Resolution Expression Profiling of Peripheral Blood CD8 Cells in Patients with Multiple Sclerosis Displays Fingolimod-Induced Immune Cell Redistribution. | 2017 | Mol. Neurobiol. | pmid:27631876 |
| Rice TC et al. | Sphingosine rescues aged mice from pulmonary pseudomonas infection. | 2017 | J. Surg. Res. | pmid:29078905 |
| Vu TM et al. | Mfsd2b is essential for the sphingosine-1-phosphate export in erythrocytes and platelets. | 2017 | Nature | pmid:29045386 |
| Becker KA et al. | Neutrophils Kill Reactive Oxygen Species-Resistant Pseudomonas aeruginosa by Sphingosine. | 2017 | Cell. Physiol. Biochem. | pmid:29040968 |
| Reinhard NR et al. | The balance between Gα-Cdc42/Rac and Gα/-RhoA pathways determines endothelial barrier regulation by sphingosine-1-phosphate. | 2017 | Mol. Biol. Cell | pmid:28954861 |
| Onuma T et al. | Sphingosine 1-phosphate (S1P) suppresses the collagen-induced activation of human platelets via S1P4 receptor. | 2017 | Thromb. Res. | pmid:28609704 |
| Meissner A | S1PR (Sphingosine-1-Phosphate Receptor) Signaling in the Regulation of Vascular Tone and Blood Pressure: Is S1PR1 Doing the Trick? | 2017 | Hypertension | pmid:28607129 |
| Cingolani F et al. | Jaspine B induces nonapoptotic cell death in gastric cancer cells independently of its inhibition of ceramide synthase. | 2017 | J. Lipid Res. | pmid:28572516 |
| Grassmé H et al. | β1-Integrin Accumulates in Cystic Fibrosis Luminal Airway Epithelial Membranes and Decreases Sphingosine, Promoting Bacterial Infections. | 2017 | Cell Host Microbe | pmid:28552668 |
| Azimzadeh K et al. | Evaluation of plasma sphingosine 1-phosphate, hepcidin and cardiovascular damage biomarkers (cardiac troponin I and homocysteine) in rats infected with brucellosis and vaccinated (Rev-1, RB-51). | 2017 | Microb. Pathog. | pmid:28533142 |
| Alqinyah M et al. | Regulator of G Protein Signaling 10 (Rgs10) Expression Is Transcriptionally Silenced in Activated Microglia by Histone Deacetylase Activity. | 2017 | Mol. Pharmacol. | pmid:28031332 |
| Dany M | Sphingosine metabolism as a therapeutic target in cutaneous melanoma. | 2017 | Transl Res | pmid:28528915 |
| Chen Y et al. | Atherosclerotic dyslipidemia revealed by plasma lipidomics on ApoE mice fed a high-fat diet. | 2017 | Atherosclerosis | pmid:28527370 |
| Seo Y et al. | Sphingosine-1-phosphate is involved in inflammatory reactions in patients with Graves' orbitopathy. | 2017 | Inflamm. Res. | pmid:28364200 |
| Segura-Ulate I et al. | FTY720-derivatives do not induce FTY720-like lymphopenia. | 2017 | J. Pharmacol. Sci. | pmid:28363412 |
| Martin GE et al. | Sphingosine's role in epithelial host defense: A natural antimicrobial and novel therapeutic. | 2017 | Biochimie | pmid:28341550 |
| Schumacher F et al. | The sphingosine 1-phosphate breakdown product, (2)-hexadecenal, forms protein adducts and glutathione conjugates in vitro. | 2017 | J. Lipid Res. | pmid:28588048 |
| Schonauer S et al. | Identification of a feedback loop involving β-glucosidase 2 and its product sphingosine sheds light on the molecular mechanisms in Gaucher disease. | 2017 | J. Biol. Chem. | pmid:28258214 |
| Kitchen SA and Weis VM | The sphingosine rheostat is involved in the cnidarian heat stress response but not necessarily in bleaching. | 2017 | J. Exp. Biol. | pmid:28250108 |
| Zeng Y | Endothelial glycocalyx as a critical signalling platform integrating the extracellular haemodynamic forces and chemical signalling. | 2017 | J. Cell. Mol. Med. | pmid:28211170 |
| Sun XJ et al. | Sphingosine-1-phosphate and its receptors in anti-neutrophil cytoplasmic antibody-associated vasculitis. | 2017 | Nephrol. Dial. Transplant. | pmid:28206609 |
| Janecke AR et al. | Deficiency of the sphingosine-1-phosphate lyase SGPL1 is associated with congenital nephrotic syndrome and congenital adrenal calcifications. | 2017 | Hum. Mutat. | pmid:28181337 |
| Ebenezer DL et al. | Epigenetic regulation of pro-inflammatory cytokine secretion by sphingosine 1-phosphate (S1P) in acute lung injury: Role of S1P lyase. | 2017 | Adv Biol Regul | pmid:27720306 |
| Skerry C et al. | Reduction of Pertussis Inflammatory Pathology by Therapeutic Treatment With Sphingosine-1-Phosphate Receptor Ligands by a Pertussis Toxin-Insensitive Mechanism. | 2017 | J. Infect. Dis. | pmid:27815382 |
| Chen T et al. | Sphingosine-1 phosphate promotes intestinal epithelial cell proliferation via S1PR2. | 2017 | Front Biosci (Landmark Ed) | pmid:27814635 |
| Feuerborn R et al. | High density lipoprotein (HDL)-associated sphingosine 1-phosphate (S1P) inhibits macrophage apoptosis by stimulating STAT3 activity and survivin expression. | 2017 | Atherosclerosis | pmid:28038379 |
| Chang N et al. | HuR mediates motility of human bone marrow-derived mesenchymal stem cells triggered by sphingosine 1-phosphate in liver fibrosis. | 2017 | J. Mol. Med. | pmid:27543493 |
| Kwon SB et al. | Phytosphingosine-1-phosphate and epidermal growth factor synergistically restore extracellular matrix in human dermal fibroblasts in vitro and in vivo. | 2017 | Int. J. Mol. Med. | pmid:28204807 |
| Wang M et al. | Automated tracking and quantification of angiogenic vessel formation in 3D microfluidic devices. | 2017 | PLoS ONE | pmid:29136008 |
| Tran HB et al. | Disrupted epithelial/macrophage crosstalk via Spinster homologue 2-mediated S1P signaling may drive defective macrophage phagocytic function in COPD. | 2017 | PLoS ONE | pmid:29112690 |
| Mensah SA et al. | Regeneration of glycocalyx by heparan sulfate and sphingosine 1-phosphate restores inter-endothelial communication. | 2017 | PLoS ONE | pmid:29023478 |
| Wang X et al. | Sphingosine 1-phosphate alleviates Coxsackievirus B3-induced myocarditis by increasing invariant natural killer T cells. | 2017 | Exp. Mol. Pathol. | pmid:28986246 |
| Werth S et al. | Obesity-stimulated aldosterone release is not related to an S1P-dependent mechanism. | 2017 | J. Endocrinol. | pmid:28970286 |
| Du Y et al. | Exosomes from Human-Induced Pluripotent Stem Cell-Derived Mesenchymal Stromal Cells (hiPSC-MSCs) Protect Liver against Hepatic Ischemia/ Reperfusion Injury via Activating Sphingosine Kinase and Sphingosine-1-Phosphate Signaling Pathway. | 2017 | Cell. Physiol. Biochem. | pmid:28934733 |
| Vijayan M et al. | Sphingosine 1-Phosphate Lyase Enhances the Activation of IKKε To Promote Type I IFN-Mediated Innate Immune Responses to Influenza A Virus Infection. | 2017 | J. Immunol. | pmid:28600291 |
| White CR et al. | High-Density Lipoprotein Regulation of Mitochondrial Function. | 2017 | Adv. Exp. Med. Biol. | pmid:28551800 |
| Dany M and Elston D | Gene expression of sphingolipid metabolism pathways is altered in hidradenitis suppurativa. | 2017 | J. Am. Acad. Dermatol. | pmid:28551069 |
| Mendoza A et al. | Lymphatic endothelial S1P promotes mitochondrial function and survival in naive T cells. | 2017 | Nature | pmid:28538737 |
| Ma S et al. | A Brain-Region-Specific Neural Pathway Regulating Germinal Matrix Angiogenesis. | 2017 | Dev. Cell | pmid:28535372 |
| Meshcheryakova A et al. | Sphingosine 1-phosphate signaling in bone remodeling: multifaceted roles and therapeutic potential. | 2017 | Expert Opin. Ther. Targets | pmid:28524744 |
| Garbowska M et al. | Sphingolipids metabolism in the salivary glands of rats with obesity and streptozotocin induced diabetes. | 2017 | J. Cell. Physiol. | pmid:28369933 |
| Turner VM and Mabbott NA | Ageing adversely affects the migration and function of marginal zone B cells. | 2017 | Immunology | pmid:28369800 |
| Müller J et al. | Differential S1P Receptor Profiles on M1- and M2-Polarized Macrophages Affect Macrophage Cytokine Production and Migration. | 2017 | Biomed Res Int | pmid:28367448 |
| King A et al. | Sphingosine-1-Phosphate Prevents Egress of Hematopoietic Stem Cells From Liver to Reduce Fibrosis. | 2017 | Gastroenterology | pmid:28363640 |
| Wollny T et al. | Sphingosine-1-Phosphate Metabolism and Its Role in the Development of Inflammatory Bowel Disease. | 2017 | Int J Mol Sci | pmid:28362332 |
| Denimal D et al. | Impairment of the Ability of HDL From Patients With Metabolic Syndrome but Without Diabetes Mellitus to Activate eNOS: Correction by S1P Enrichment. | 2017 | Arterioscler. Thromb. Vasc. Biol. | pmid:28360087 |
| Gusman DH and Shoemake C | Evaluation and Optimization of designed Sphingosine-1-Phosphate (S1P) Receptor Subtype 1 Modulators for the Management of Multiple Sclerosis. | 2017 | Yale J Biol Med | pmid:28356890 |
| Andrieu G et al. | Sphingosine 1-phosphate signaling through its receptor S1P promotes chromosome segregation and mitotic progression. | 2017 | Sci Signal | pmid:28351953 |
| Becker S et al. | Low sphingosine-1-phosphate plasma levels are predictive for increased mortality in patients with liver cirrhosis. | 2017 | PLoS ONE | pmid:28334008 |
| Kim HJ et al. | Novel involvement of RhebL1 in sphingosylphosphorylcholine-induced keratin phosphorylation and reorganization: Binding to and activation of AKT1. | 2017 | Oncotarget | pmid:28209923 |
| Serafimidis I et al. | Pancreas lineage allocation and specification are regulated by sphingosine-1-phosphate signalling. | 2017 | PLoS Biol. | pmid:28248965 |
| Lee HM et al. | Oncogenic S1P signalling in EBV-associated nasopharyngeal carcinoma activates AKT and promotes cell migration through S1P receptor 3. | 2017 | J. Pathol. | pmid:28240350 |
| Rieck M et al. | Ceramide synthase 2 facilitates S1P-dependent egress of thymocytes into the circulation in mice. | 2017 | Eur. J. Immunol. | pmid:28198542 |
| Bruno M et al. | Sphingosine 1-phosphate signaling axis mediates fibroblast growth factor 2-induced proliferation and survival of murine auditory neuroblasts. | 2017 | Biochim. Biophys. Acta | pmid:28188805 |
| Qi H et al. | Analysis of sphingolipids in human corneal fibroblasts from normal and keratoconus patients. | 2017 | J. Lipid Res. | pmid:28188148 |
| Ren K et al. | ApoA-I/SR-BI modulates S1P/S1PR2-mediated inflammation through the PI3K/Akt signaling pathway in HUVECs. | 2017 | J. Physiol. Biochem. | pmid:28181168 |
| Abe A et al. | Preferential hydrolysis of truncated oxidized glycerophospholipids by lysosomal phospholipase A2. | 2017 | J. Lipid Res. | pmid:27993948 |
| Fujii A et al. | Selective Absorption of Dietary Sphingoid Bases from the Intestine via Efflux by P-Glycoprotein in Rats. | 2017 | J. Nutr. Sci. Vitaminol. | pmid:28367925 |
sphingosine
sphingosine is a lipid of Sphingolipids (SP) class.
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