sphingosine

sphingosine is a lipid of Sphingolipids (SP) class.

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There are no associated biomedical information in the current reference collection.

Current reference collection contains 26061 references associated with sphingosine in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

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Authors Title Published Journal PubMed Link
Yin GJ et al. [Antitumor effect of sphingosine kinase 1 inhibitor in combination with chemotherapy on SGC7901 gastric cancer cells in vitro]. 2012 Zhonghua Zhong Liu Za Zhi pmid:22780925
Liu SQ et al. [Sphingosine kinase 1 enhances the proliferation and invasion of human colon cancer LoVo cells through up-regulating FAK pathway and the expression of ICAM-1 and VCAM-1]. 2013 Zhonghua Zhong Liu Za Zhi pmid:24054007
Liu SQ et al. [Effect of sphingosine kinase 1 on the apoptosis, migration and invasion of colon cancer HT-29 cells and its molecular mechanisms]. 2011 Zhonghua Zhong Liu Za Zhi pmid:21575515
Chen L et al. [Inhibition of alphastatin on angiogenesis in human endothelial cells and the mechanism thereof: an experimental study]. 2006 Zhonghua Yi Xue Za Zhi pmid:16784712
Cai JQ et al. [Study of the effects of immunosuppressive agents on human islet cells in vitro]. 2005 Zhonghua Yi Xue Za Zhi pmid:15932724
Yu HM et al. [Regulation of sphingosine kinase 1 in the TNF-α-induced expression of MUC5AC in airway epithelial cells]. 2011 Zhonghua Yi Xue Za Zhi pmid:21418911
Liao AJ et al. [The study of FTY720 on inducing apoptosis and autophagy in multiple myeloma cell line U266]. 2011 Zhonghua Xue Ye Xue Za Zhi pmid:22339823
Yang LX et al. [Association between murine double minute 2 expression and AngII and ceramide induced endothelial cells apoptosis]. 2007 Zhonghua Xin Xue Guan Bing Za Zhi pmid:18206046
Bao XH et al. [Role and related mechanism of S1P/S1P1 signal pathway during post conditioning of hypertrophic cardiomyocytes]. 2016 Zhonghua Xin Xue Guan Bing Za Zhi pmid:27220580
Song JH et al. [FTY720-induced lymphocyte apoptosis inhibits acute graft versus host disease in rat small bowel transplantation]. 2010 Zhonghua Wei Chang Wai Ke Za Zhi pmid:20099165
Zhang L et al. [Study the mechanisms and inducing transplantation immune tolerance of FTY720]. 2003 Zhonghua Wai Ke Za Zhi pmid:14766054
Liu H et al. [Effect of C8-ceramide on apoptosis of alveolar type II epithelial cells]. 2015 Zhonghua Jie He He Hu Xi Za Zhi pmid:26702858
Zhu GQ et al. [Effect of FTY720 on glomerulosclerosis and expression of cell cycle regulatory proteins in subtotally nephrectomized rats]. 2007 Zhonghua Er Ke Za Zhi pmid:18339282
Xie M and Zhou JH [FTY720 reduces peritubular micrangium loss in renal interstitial fibrotic rats]. 2009 Zhonghua Er Ke Za Zhi pmid:19951479
Tang Y et al. [Updates on clinicopathologic findings of Niemann-Pick disease type C]. 2010 Zhonghua Bing Li Xue Za Zhi pmid:20654165
Jiang JY et al. [FTY720 attenuates rat anti-Thy-1 mesangial proliferative glomerulonephritis by inhibition of transforming growth factor β1-connective tissue growth factor pathway]. 2012 Zhonghua Bing Li Xue Za Zhi pmid:22455887
Li Y and Yu KL [Advances in thrombin-protease-activated receptor 1-sphingosine 1-phosphate pathway during sepsis]. 2009 Zhongguo Wei Zhong Bing Ji Jiu Yi Xue pmid:19278594
Huang Y et al. [Ceramide participates in cell programmed death induced by Type II anti-CD20 mAb]. 2015 Zhong Nan Da Xue Xue Bao Yi Xue Ban pmid:26739069
Xiong HB et al. [Effect of mono and combination therapy with FTY720 and ICAM-1 mAb for mouse-to-rat cardiac xenotransplantation]. 2007 Zhong Nan Da Xue Xue Bao Yi Xue Ban pmid:17344585
Huang RT [Structure of brain gangliosides and of neuraminic-acid-containing oligosaccharides in milk]. 1973 Zentralbl Veterinarmed A pmid:4196659
Brinkmann V FTY720: mechanism of action and potential benefit in organ transplantation. 2004 Yonsei Med. J. pmid:15627289
Bae JH et al. Cloning and functional characterization of the SUR2/SYR2 gene encoding sphinganine hydroxylase in Pichia ciferrii. 2004 Yeast pmid:15116344
Gusman DH and Shoemake C Evaluation and Optimization of designed Sphingosine-1-Phosphate (S1P) Receptor Subtype 1 Modulators for the Management of Multiple Sclerosis. 2017 Yale J Biol Med pmid:28356890
Chiba K [New therapeutic approach for autoimmune diseases by the sphingosine 1-phosphate receptor modulator, fingolimod (FTY720)]. 2009 Yakugaku Zasshi pmid:19483408
Yu XQ et al. Pharmacokinetic/pharmacodynamic modelling of 2-acetyl-4(5)-tetrahydroxybutyl imidazole-induced peripheral lymphocyte sequestration through increasing lymphoid sphingosine 1-phosphate. 2010 Xenobiotica pmid:20175664
Taylor S et al. The utility of pharmacokinetic-pharmacodynamic modeling in the discovery and optimization of selective S1P(1) agonists. 2012 Xenobiotica pmid:22225501
Syuto T et al. Mammalian Diaphanous (mDia) may be involved in the signal transduction of sphingosine-1-phosphate on developing actin stress fiber of human fibroblasts. 2009 Jul-Aug Wound Repair Regen pmid:19614924
Watterson KR et al. Regulation of fibroblast functions by lysophospholipid mediators: potential roles in wound healing. 2007 Sep-Oct Wound Repair Regen pmid:17971005
Yoneda H et al. A prospective, multicenter, randomized study of the efficacy of eicosapentaenoic acid for cerebral vasospasm: the EVAS study. 2014 World Neurosurg pmid:23032083
Lei YC et al. C5a/C5aR pathway is essential for up-regulating SphK1 expression through p38-MAPK activation in acute liver failure. 2016 World J. Gastroenterol. pmid:28028363
Nguyen AV et al. STAT3 and sphingosine-1-phosphate in inflammation-associated colorectal cancer. 2014 World J. Gastroenterol. pmid:25132744
Sano N et al. New drug delivery system for liver sinusoidal endothelial cells for ischemia-reperfusion injury. 2015 World J. Gastroenterol. pmid:26668502
Hu WM et al. Effect of S1P5 on proliferation and migration of human esophageal cancer cells. 2010 World J. Gastroenterol. pmid:20397263
He JH et al. Effect of 2-amino-2-(2-(4-octylphenyl) ethyl) propane-1,3-diol hydrochloride (FTY 720) on immune liver injury in mice. 2005 World J. Gastroenterol. pmid:15641148
Ren J et al. Expression of sphingosine kinase gene in the interactions between human gastric carcinoma cell and vascular endothelial cell. 2002 World J. Gastroenterol. pmid:12174364
Zhang XF et al. Apoptosis of human colon carcinoma HT-29 cells induced by ceramide. 2006 World J. Gastroenterol. pmid:16773715
Lei YC et al. Inhibition of sphingosine kinase 1 ameliorates acute liver failure by reducing high-mobility group box 1 cytoplasmic translocation in liver cells. 2015 World J. Gastroenterol. pmid:26676341
Wang J et al. Mechanisms involved in ceramide-induced cell cycle arrest in human hepatocarcinoma cells. 2007 World J. Gastroenterol. pmid:17373752
Jin L et al. The SphKs/S1P/S1PR1 axis in immunity and cancer: more ore to be mined. 2016 World J Surg Oncol pmid:27129720
Ohba M et al. Long-term graft acceptance in rat heart transplantation by CTLA4Ig gene transfection combined with FTY720 treatment. 2001 World J Surg pmid:11344387
Fazekas F et al. Fingolimod in the treatment algorithm of relapsing remitting multiple sclerosis: a statement of the Central and East European (CEE) MS Expert Group. 2012 Wien Med Wochenschr pmid:22895849
Zhang SQ et al. Mutation of G234 amino acid residue in candida albicans drug-resistance-related protein Rta2p is associated with fluconazole resistance and dihydrosphingosine transport. 2015 Virulence pmid:26220356
Walsh KB et al. Treatment with a sphingosine analog does not alter the outcome of a persistent virus infection. 2010 Virology pmid:19962171
Seo YJ and Hahm B Sphingosine analog AAL-R promotes activation of LCMV-infected dendritic cells. 2014 Viral Immunol. pmid:24605791
Stroh A et al. Influence of a phytosphingosine-containing chlorhexidine shampoo on superficial bacterial counts and bacterial adherence to canine keratinocytes. 2010 Vet. Microbiol. pmid:19781867
Poersch AB et al. Involvement of oxidative stress in subacute toxicity induced by fumonisin B1 in broiler chicks. 2014 Vet. Microbiol. pmid:25219295
Hilton H et al. Evaluation of four topical preparations for the treatment of cannon hyperkeratosis in a horse. 2008 Vet. Dermatol. pmid:19055613
Mani R et al. Non-immunosuppressive FTY720-derivative OSU-2S mediates reactive oxygen species-mediated cytotoxicity in canine B-cell lymphoma. 2017 Vet Comp Oncol pmid:27136276
Poti F et al. Effect of sphingosine 1-phosphate (S1P) receptor agonists FTY720 and CYM5442 on atherosclerosis development in LDL receptor deficient (LDL-R⁻/⁻) mice. 2012 Vascul. Pharmacol. pmid:22459073
Zhang H et al. Ceramide enhances COX-2 expression and VSMC contractile hyperreactivity via ER stress signal activation. 2017 Vascul. Pharmacol. pmid:28797762