sphingosine

sphingosine is a lipid of Sphingolipids (SP) class.

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There are no associated biomedical information in the current reference collection.

Current reference collection contains 26061 references associated with sphingosine in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

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Authors Title Published Journal PubMed Link
Van Brocklyn JR et al. Sphingosine 1-phosphate-induced cell rounding and neurite retraction are mediated by the G protein-coupled receptor H218. 1999 J. Biol. Chem. pmid:9988698
Roze LV and Linz JE Lovastatin triggers an apoptosis-like cell death process in the fungus Mucor racemosus. 1998 Fungal Genet. Biol. pmid:9974223
Goetzl EJ et al. Lysophosphatidic acid and sphingosine 1-phosphate protection of T cells from apoptosis in association with suppression of Bax. 1999 J. Immunol. pmid:9973477
Skrzypek MS et al. Analysis of phosphorylated sphingolipid long-chain bases reveals potential roles in heat stress and growth control in Saccharomyces. 1999 J. Bacteriol. pmid:9973338
Rodriguez-Lafrasse C and Vanier MT Sphingosylphosphorylcholine in Niemann-Pick disease brain: accumulation in type A but not in type B. 1999 Neurochem. Res. pmid:9972865
Alemany R et al. Formyl peptide receptor signaling in HL-60 cells through sphingosine kinase. 1999 J. Biol. Chem. pmid:9933590
Yohe HC et al. C20-sphingosine as a determining factor in aggregation of gangliosides. 1976 J. Biol. Chem. pmid:993205
Zhang G et al. Comparative analysis of three murine G-protein coupled receptors activated by sphingosine-1-phosphate. 1999 Gene pmid:9931453
Hung WC et al. Activation of caspase-3-like proteases in apoptosis induced by sphingosine and other long-chain bases in Hep3B hepatoma cells. 1999 Biochem. J. pmid:9931312
Riboni L et al. Predominance of the acylation route in the metabolic processing of exogenous sphingosine in neural and extraneural cells in culture. 1999 Biochem. J. pmid:9931310
Sato K et al. Activation of phospholipase C-Ca2+ system by sphingosine 1-phosphate in CHO cells transfected with Edg-3, a putative lipid receptor. 1999 FEBS Lett. pmid:9928946
Centeno F et al. Partial lithium-associated protection against apoptosis induced by C2-ceramide in cerebellar granule neurons. 1998 Neuroreport pmid:9926873
Kiuchi M et al. Synthesis and biological evaluation of 2,2-disubstituted 2-aminoethanols: analogues of FTY720. 1998 Bioorg. Med. Chem. Lett. pmid:9925439
Orlati S et al. Sphingosylphosphorylcholine and sphingosine-1-phosphate mobilize cytosolic calcium through different mechanisms in human airway epithelial cells. 1998 Cell Calcium pmid:9924630
Troncoso P et al. Prophylaxis of acute renal allograft rejection using FTY720 in combination with subtherapeutic doses of cyclosporine. 1999 Transplantation pmid:9921811
Soboloff J et al. Acyl chain length-specific ceramide-induced changes in intracellular Ca2+ concentration and progesterone production are not regulated by tumor necrosis factor alpha in hen granulosa cells. 1999 Biol. Reprod. pmid:9915989
Wang E et al. Fumonisin B1 consumption by rats causes reversible, dose-dependent increases in urinary sphinganine and sphingosine. 1999 J. Nutr. pmid:9915902
Jennemann R et al. Novel glycoinositolphosphosphingolipids, basidiolipids, from Agaricus. 1999 Eur. J. Biochem. pmid:9914511
Xu FY et al. N-Acetylsphingosine stimulates phosphatidylglycerolphosphate synthase activity in H9c2 cardiac cells. 1999 Biochem. J. pmid:9895291
Yanagawa Y et al. FTY720, a novel immunosuppressant, induces sequestration of circulating mature lymphocytes by acceleration of lymphocyte homing in rats, III. Increase in frequency of CD62L-positive T cells in Peyer's patches by FTY720-induced lymphocyte homing. 1998 Immunology pmid:9893050
Reiners JJ and Clift RE Aryl hydrocarbon receptor regulation of ceramide-induced apoptosis in murine hepatoma 1c1c7 cells. A function independent of aryl hydrocarbon receptor nuclear translocator. 1999 J. Biol. Chem. pmid:9891021
Imokawa G et al. Sphingosylphosphorylcholine is a potent inducer of intercellular adhesion molecule-1 expression in human keratinocytes. 1999 J. Invest. Dermatol. pmid:9886270
Raeder EM et al. Sphingosine blocks human polymorphonuclear leukocyte phagocytosis through inhibition of mitogen-activated protein kinase activation. 1999 Blood pmid:9885231
Sato K et al. Possible involvement of cell surface receptors in sphingosine 1-phosphate-induced activation of extracellular signal-regulated kinase in C6 glioma cells. 1999 Mol. Pharmacol. pmid:9882706
MacKichan ML and DeFranco AL Role of ceramide in lipopolysaccharide (LPS)-induced signaling. LPS increases ceramide rather than acting as a structural homolog. 1999 J. Biol. Chem. pmid:9880559
Sato K et al. Downregulation of mRNA expression of Edg-3, a putative sphingosine 1-phosphate receptor coupled to Ca2+ signaling, during differentiation of HL-60 leukemia cells. 1998 Biochem. Biophys. Res. Commun. pmid:9878524
Qiao L et al. Synthesis and evaluation of a photolyzable derivative of sphingosine 1-phosphate--caged SPP. 1998 Bioorg. Med. Chem. Lett. pmid:9871527
Li S et al. Chemical synthesis of D-ribo-phytosphingosine-1-phosphate, a potential modulator of cellular processes. 1999 J. Lipid Res. pmid:9869657
Miyata Y et al. Prolongation of concordant xenograft survival by treatment with FTY720. 1998 Transplant. Proc. pmid:9865334
Scheid MP et al. Ceramide and cyclic adenosine monophosphate (cAMP) induce cAMP response element binding protein phosphorylation via distinct signaling pathways while having opposite effects on myeloid cell survival. 1999 Blood pmid:9864164
Gumprecht LA et al. Development of fumonisin-induced hepatotoxicity and pulmonary edema in orally dosed swine: morphological and biochemical alterations. 1998 Nov-Dec Toxicol Pathol pmid:9864095
Holopainen JM et al. Sphingomyelinase induces lipid microdomain formation in a fluid phosphatidylcholine/sphingomyelin membrane. 1998 Biochemistry pmid:9860872
Bektas M et al. Induction of apoptosis by synthetic ceramide analogues in the human keratinocyte cell line HaCaT. 1998 Exp. Dermatol. pmid:9858137
Gonda K et al. The novel sphingosine 1-phosphate receptor AGR16 is coupled via pertussis toxin-sensitive and -insensitive G-proteins to multiple signalling pathways. 1999 Biochem. J. pmid:9854026
Zheng T et al. C2-ceramide attenuates prostaglandin F2alpha-induced vasoconstriction and elevation of [Ca2+]i in canine cerebral vascular smooth muscle. 1998 Neurosci. Lett. pmid:9853716
Chen PF et al. Ca2+ signaling induced by sphingosylphosphorylcholine and sphingosine 1-phosphate via distinct mechanisms in rat glomerular mesangial cells. 1998 Kidney Int. pmid:9844123
Abbas HK et al. Phytotoxicity and cytotoxicity of the fumonisin C and P series of mycotoxins from Fusarium spp. fungi. 1998 Toxicon pmid:9839687
Abbas HK et al. Ultrastructural effects of AAL-toxin TA from the fungus Alternaria alternata on black nightshade (Solanum nigrum L.) leaf discs and correlation with biochemical measures of toxicity. 1998 Toxicon pmid:9839666
Yan H et al. Immunosuppressive effect of FTY 720 on autoimmune diabetes models. 1998 Transplant. Proc. pmid:9838514
Suzuki K et al. Immunosuppressive effect of FTY 720 on rat pancreas allograft. 1998 Transplant. Proc. pmid:9838506
Xia P et al. Tumor necrosis factor-alpha induces adhesion molecule expression through the sphingosine kinase pathway. 1998 Proc. Natl. Acad. Sci. U.S.A. pmid:9826677
Guo C et al. Differential stimulation of proline-rich tyrosine kinase 2 and mitogen-activated protein kinase by sphingosine 1-phosphate. 1998 Eur. J. Biochem. pmid:9826186
Grosman N Influence of probes for calcium-calmodulin and protein kinase C signalling on the plasma membrane Ca2+-ATPase activity of rat synaptosomes and leukocyte membranes. 1998 Immunopharmacology pmid:9826030
Soeda S et al. Tumor necrosis factor-alpha-induced release of plasminogen activator inhibitor-1 from human umbilical vein endothelial cells: involvement of intracellular ceramide signaling event. 1998 Biochim. Biophys. Acta pmid:9824663
Nyberg L et al. Digestion of ceramide by human milk bile salt-stimulated lipase. 1998 J. Pediatr. Gastroenterol. Nutr. pmid:9822324
Chigorno V et al. Human fibroblasts in culture metabolize differently exogenous G(M3) ganglioside species containing C18 and C20 sphingosine. 1998 Acta Biochim. Pol. pmid:9821869
Ayar A et al. Mobilization of intracellular calcium by intracellular flash photolysis of caged dihydrosphingosine in cultured neonatal rat sensory neurones. 1998 Acta Biochim. Pol. pmid:9821863
Igarashi Y and Yatomi Y Sphingosine 1-phosphate is a blood constituent released from activated platelets, possibly playing a variety of physiological and pathophysiological roles. 1998 Acta Biochim. Pol. pmid:9821862
Yorek MA et al. Opposing effects of tumour necrosis factor alpha and hyperosmolarity on Na+/myo-inositol co-transporter mRNA levels and myo-inositol accumulation by 3T3-L1 adipocytes. 1998 Biochem. J. pmid:9820807
Schwartz GK et al. A pilot clinical/pharmacological study of the protein kinase C-specific inhibitor safingol alone and in combination with doxorubicin. 1997 Clin. Cancer Res. pmid:9815717