sphingosine

sphingosine is a lipid of Sphingolipids (SP) class.

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There are no associated biomedical information in the current reference collection.

Current reference collection contains 26061 references associated with sphingosine in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

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Authors Title Published Journal PubMed Link
Tang HB et al. S1P/S1PR3 signaling mediated proliferation of pericytes via Ras/pERK pathway and CAY10444 had beneficial effects on spinal cord injury. 2018 Biochem. Biophys. Res. Commun. pmid:29534963
Yu FC et al. Protective effect of sphingosine-1-phosphate for chronic intermittent hypoxia-induced endothelial cell injury. 2018 Biochem. Biophys. Res. Commun. pmid:29550481
Nádró B et al. [The role of apolipoprotein M and sphingosine 1-phosphate axis in the prevention of atherosclerosis]. 2018 Orv Hetil pmid:29376427
Deshpande GP et al. Sphingosine-1-phosphate (S1P) activates STAT3 to protect against de novo acute heart failure (AHF). 2018 Life Sci. pmid:29373815
Książek M et al. Arteriovenous Sphingosine-1-Phosphate Differences Across Selected Organs of the Rat. 2018 Cell. Physiol. Biochem. pmid:29316552
Huang Y et al. S1P-dependent interorgan trafficking of group 2 innate lymphoid cells supports host defense. 2018 Science pmid:29302015
Ahn EH et al. Sphingosine Induces Apoptosis and Down-regulation of in PAX3-FOXO1-positive Alveolar Rhabdomyosarcoma Cells Irrespective of Mutation. 2018 Anticancer Res. pmid:29277758
Zhang YL et al. Non-invasive assessment of culture media from goat cloned embryos associated with subjective morphology by gas chromatography - mass spectroscopy-based metabolomic analysis. 2018 Anim. Sci. J. pmid:28833899
Zheng Y et al. A Sphingosine-type cerebroside in Clavicorona pyxidata induce fruit body formation. 2018 Nat. Prod. Res. pmid:28347179
Ogretmen B Sphingolipid metabolism in cancer signalling and therapy. 2018 Nat. Rev. Cancer pmid:29147025
Powell JA et al. Targeting sphingosine kinase 1 induces MCL1-dependent cell death in acute myeloid leukemia. 2017 Blood pmid:27956387
Miyabe C et al. A sphingosine 1-phosphate receptor agonist ameliorates animal model of vasculitis. 2017 Inflamm. Res. pmid:27942751
Frias MA et al. High-density lipoprotein-associated sphingosine-1-phosphate activity in heterozygous familial hypercholesterolaemia. 2017 Eur. J. Clin. Invest. pmid:27861771
Fang V et al. Gradients of the signaling lipid S1P in lymph nodes position natural killer cells and regulate their interferon-γ response. 2017 Nat. Immunol. pmid:27841869
Wang R et al. Hepatic Stellate Cell Selective Disruption of Dynamin-2 GTPase Increases Murine Fibrogenesis through Up-Regulation of Sphingosine-1 Phosphate-Induced Cell Migration. 2017 Am. J. Pathol. pmid:27840081
Pal SK et al. A phase 2 study of the sphingosine-1-phosphate antibody sonepcizumab in patients with metastatic renal cell carcinoma. 2017 Cancer pmid:27727447
Pierucci F et al. Non-dioxin-like organic toxicant PCB153 modulates sphingolipid metabolism in liver progenitor cells: its role in Cx43-formed gap junction impairment. 2017 Arch. Toxicol. pmid:27318803
Takahashi C et al. Vehicle-dependent Effects of Sphingosine 1-phosphate on Plasminogen Activator Inhibitor-1 Expression. 2017 J. Atheroscler. Thromb. pmid:28321011
Kitamura T et al. Phytosphingosine degradation pathway includes fatty acid α-oxidation reactions in the endoplasmic reticulum. 2017 Proc. Natl. Acad. Sci. U.S.A. pmid:28289220
Höglinger D et al. Trifunctional lipid probes for comprehensive studies of single lipid species in living cells. 2017 Proc. Natl. Acad. Sci. U.S.A. pmid:28154130
Pierucci F et al. Vitamin D protects against Aβ peptide cytotoxicity in differentiated human neuroblastoma SH- SY5Y cells: A role for S1P1/p38MAPK/ATF4 axis. 2017 Neuropharmacology pmid:28077289
Hajny S and Christoffersen C A Novel Perspective on the ApoM-S1P Axis, Highlighting the Metabolism of ApoM and Its Role in Liver Fibrosis and Neuroinflammation. 2017 Int J Mol Sci pmid:28749426
Bertlich M et al. Fingolimod (FTY-720) is Capable of Reversing Tumor Necrosis Factor Induced Decreases in Cochlear Blood Flow. 2017 Otol. Neurotol. pmid:28742634
Koch A et al. Vitamin D Supplementation Enhances C18(dihydro)ceramide Levels in Type 2 Diabetes Patients. 2017 Int J Mol Sci pmid:28714882
Yanagawa D et al. Synthesis and degradation of long-chain base phosphates affect fumonisin B-induced cell death in Arabidopsis thaliana. 2017 J. Plant Res. pmid:28303405
Oh YT et al. DR5 suppression induces sphingosine-1-phosphate-dependent TRAF2 polyubiquitination, leading to activation of JNK/AP-1 and promotion of cancer cell invasion. 2017 Cell Commun. Signal pmid:28482915
Tessema EN et al. Isolation and structural characterization of glucosylceramides from Ethiopian plants by LC/APCI-MS/MS. 2017 J Pharm Biomed Anal pmid:28463779
Fan Q et al. Sphingosine-1-phosphate promotes ovarian cancer cell proliferation by disrupting Hippo signaling. 2017 Oncotarget pmid:28460443
Patmanathan SN et al. Mechanisms of sphingosine 1-phosphate receptor signalling in cancer. 2017 Cell. Signal. pmid:28302566
Fan C et al. Autophagy inhibits C2-ceramide-mediated cell death by decreasing the reactive oxygen species levels in SH-SY5Y cells. 2017 Neurosci. Lett. pmid:28288862
Rothhammer V et al. Sphingosine 1-phosphate receptor modulation suppresses pathogenic astrocyte activation and chronic progressive CNS inflammation. 2017 Proc. Natl. Acad. Sci. U.S.A. pmid:28167760
Ebenezer DL et al. Epigenetic regulation of pro-inflammatory cytokine secretion by sphingosine 1-phosphate (S1P) in acute lung injury: Role of S1P lyase. 2017 Adv Biol Regul pmid:27720306
Moritz E et al. Reference intervals for serum sphingosine-1-phosphate in the population-based Study of Health in Pomerania. 2017 Clin. Chim. Acta pmid:28159438
Lin MH et al. Linear ion-trap MS with high-resolution MS reveals structural diversity of 1-O-acylceramide family in mouse epidermis. 2017 J. Lipid Res. pmid:28154204
Winkler MS et al. Sphingosine-1-Phosphate: A Potential Biomarker and Therapeutic Target for Endothelial Dysfunction and Sepsis? 2017 Shock pmid:27922551
Barbour M et al. Effect of sphingosine kinase modulators on interleukin-1β release, sphingosine 1-phosphate receptor 1 expression and experimental autoimmune encephalomyelitis. 2017 Br. J. Pharmacol. pmid:27864936
Al-Jarallah A and Oriowo M The effect of sphingosine-1-phosphate on colonic smooth muscle contractility: Modulation by TNBS-induced colitis. 2017 PLoS ONE pmid:28493876
Thieme M et al. Sphingosine-1-phosphate modulators in inflammatory skin diseases - lining up for clinical translation. 2017 Exp. Dermatol. pmid:27574180
Cubells-Baeza N et al. Identification of the ligand of Pru p 3, a peach LTP. 2017 Plant Mol. Biol. pmid:28299506
Nicholas SE et al. Unravelling the interplay of sphingolipids and TGF-β signaling in the human corneal stroma. 2017 PLoS ONE pmid:28806736
Lee SY et al. Adipocyte-Specific Deficiency of De Novo Sphingolipid Biosynthesis Leads to Lipodystrophy and Insulin Resistance. 2017 Diabetes pmid:28698261
Jang Y et al. Gamma-tocotrienol profoundly alters sphingolipids in cancer cells by inhibition of dihydroceramide desaturase and possibly activation of sphingolipid hydrolysis during prolonged treatment. 2017 J. Nutr. Biochem. pmid:28456081
Ko J et al. Sphingosine-1-Phosphate Mediates Fibrosis in Orbital Fibroblasts in Graves' Orbitopathy. 2017 Invest. Ophthalmol. Vis. Sci. pmid:28492873
Zhang H et al. Ceramide enhances COX-2 expression and VSMC contractile hyperreactivity via ER stress signal activation. 2017 Vascul. Pharmacol. pmid:28797762
Navarrete A et al. A metabolomic approach shows sphingosine 1-phosphate and lysophospholipids as mediators of the therapeutic effect of liver growth factor in emphysema. 2017 J Pharm Biomed Anal pmid:28314215
Shirakawa H et al. Sphingosine-1-phosphate induces Ca signaling and CXCL1 release via TRPC6 channel in astrocytes. 2017 Glia pmid:28300348
Dyckman AJ Modulators of Sphingosine-1-phosphate Pathway Biology: Recent Advances of Sphingosine-1-phosphate Receptor 1 (S1P) Agonists and Future Perspectives. 2017 J. Med. Chem. pmid:28291340
Dela Paz NG et al. Shear stress induces Gα activation independently of G protein-coupled receptor activation in endothelial cells. 2017 Am. J. Physiol., Cell Physiol. pmid:28148497
Green CL et al. The effects of graded levels of calorie restriction: IX. Global metabolomic screen reveals modulation of carnitines, sphingolipids and bile acids in the liver of C57BL/6 mice. 2017 Aging Cell pmid:28139067
Vishwakarma S et al. Altered Expression of Sphingosine-1-Phosphate Metabolizing Enzymes in Oral Cancer Correlate With Clinicopathological Attributes. 2017 Cancer Invest. pmid:28135860