Edvardson S et al. |
Deficiency of the alkaline ceramidase ACER3 manifests in early childhood by progressive leukodystrophy. |
2016 |
J. Med. Genet. |
pmid:26792856
|
Li W et al. |
Sphingosylphosphorylcholine promotes the differentiation of resident Sca-1 positive cardiac stem cells to cardiomyocytes through lipid raft/JNK/STAT3 and β-catenin signaling pathways. |
2016 |
Biochim. Biophys. Acta |
pmid:27066979
|
Desai P et al. |
Dyslipidemia regulates thrombospondin-1-induced vascular smooth muscle cell chemotaxis. |
2015 |
Mol. Cell. Biochem. |
pmid:26350564
|
Wilson PC et al. |
Inhibition of Sphingosine Kinase 1 Ameliorates Angiotensin II-Induced Hypertension and Inhibits Transmembrane Calcium Entry via Store-Operated Calcium Channel. |
2015 |
Mol. Endocrinol. |
pmid:25871850
|
Jernigan PL et al. |
The role of sphingolipids in endothelial barrier function. |
2015 |
Biol. Chem. |
pmid:25867999
|
Egom EE et al. |
The effect of the sphingosine-1-phosphate analogue FTY720 on atrioventricular nodal tissue. |
2015 |
J. Cell. Mol. Med. |
pmid:25864579
|
Ohkawa R et al. |
Possible involvement of sphingomyelin in the regulation of the plasma sphingosine 1-phosphate level in human subjects. |
2015 |
Clin. Biochem. |
pmid:25863111
|
Radue EW et al. |
Correlation between brain volume loss and clinical and MRI outcomes in multiple sclerosis. |
2015 |
Neurology |
pmid:25632085
|
Signoriello E et al. |
Fingolimod efficacy in multiple sclerosis associated with Sjogren syndrome. |
2015 |
Acta Neurol. Scand. |
pmid:25622658
|
Kang H et al. |
The Therapeutic Effects of Human Mesenchymal Stem Cells Primed with Sphingosine-1 Phosphate on Pulmonary Artery Hypertension. |
2015 |
Stem Cells Dev. |
pmid:25761906
|
Carrera I et al. |
A comparative evaluation of a novel vaccine in APP/PS1 mouse models of Alzheimer's disease. |
2015 |
Biomed Res Int |
pmid:25759822
|
Ueda N |
Ceramide-induced apoptosis in renal tubular cells: a role of mitochondria and sphingosine-1-phoshate. |
2015 |
Int J Mol Sci |
pmid:25751724
|
Zhao S and Li J |
Sphingosine-1-phosphate induces the migration of thyroid follicular carcinoma cells through the microRNA-17/PTK6/ERK1/2 pathway. |
2015 |
PLoS ONE |
pmid:25748447
|
Issa NP and Hentati A |
VZV encephalitis that developed in an immunized patient during fingolimod therapy. |
2015 |
Neurology |
pmid:25416038
|
Till KJ et al. |
Expression of functional sphingosine-1 phosphate receptor-1 is reduced by B cell receptor signaling and increased by inhibition of PI3 kinase δ but not SYK or BTK in chronic lymphocytic leukemia cells. |
2015 |
J. Immunol. |
pmid:25632006
|
Liu M et al. |
Uncleaved ApoM signal peptide is required for formation of large ApoM/sphingosine 1-phosphate (S1P)-enriched HDL particles. |
2015 |
J. Biol. Chem. |
pmid:25627684
|
O'Sullivan C and Dev KK |
Galactosylsphingosine (psychosine)-induced demyelination is attenuated by sphingosine 1-phosphate signalling. |
2015 |
J. Cell. Sci. |
pmid:26359302
|
Duan J and Merrill AH |
1-Deoxysphingolipids Encountered Exogenously and Made de Novo: Dangerous Mysteries inside an Enigma. |
2015 |
J. Biol. Chem. |
pmid:25947379
|
Slowik A et al. |
The sphingosine 1-phosphate receptor agonist FTY720 is neuroprotective after cuprizone-induced CNS demyelination. |
2015 |
Br. J. Pharmacol. |
pmid:25220526
|
Kurano M et al. |
LDL receptor and ApoE are involved in the clearance of ApoM-associated sphingosine 1-phosphate. |
2015 |
J. Biol. Chem. |
pmid:25505264
|
Konstantinou D et al. |
Growth factors mediated differentiation of mesenchymal stem cells to cardiac polymicrotissue using hanging drop and bioreactor. |
2015 |
Cell Biol. Int. |
pmid:25492631
|
Frati A et al. |
Role of sphingosine kinase/S1P axis in ECM remodeling of cardiac cells elicited by relaxin. |
2015 |
Mol. Endocrinol. |
pmid:25415609
|
Jaramillo-Gómez J et al. |
Overexpression of DJ-1 protects against C2-ceramide-induced neuronal death through activation of the PI3K/AKT pathway and inhibition of autophagy. |
2015 |
Neurosci. Lett. |
pmid:26222260
|
Landi D et al. |
Oral fingolimod reduces glutamate-mediated intracortical excitability in relapsing-remitting multiple sclerosis. |
2015 |
Clin Neurophysiol |
pmid:25022794
|
Cukkemane N et al. |
Anti-adherence and bactericidal activity of sphingolipids against Streptococcus mutans. |
2015 |
Eur. J. Oral Sci. |
pmid:26094809
|
Burow P et al. |
Activation of ATP secretion via volume-regulated anion channels by sphingosine-1-phosphate in RAW macrophages. |
2015 |
Pflugers Arch. |
pmid:24965069
|
Iwabuchi K et al. |
Role of Ceramide from Glycosphingolipids and Its Metabolites in Immunological and Inflammatory Responses in Humans. |
2015 |
Mediators Inflamm. |
pmid:26609196
|
Mahajan-Thakur S et al. |
Sphingosine-1-Phosphate and Its Receptors: A Mutual Link between Blood Coagulation and Inflammation. |
2015 |
Mediators Inflamm. |
pmid:26604433
|
Barnawi J et al. |
Potential Link between the Sphingosine-1-Phosphate (S1P) System and Defective Alveolar Macrophage Phagocytic Function in Chronic Obstructive Pulmonary Disease (COPD). |
2015 |
PLoS ONE |
pmid:26485657
|
Moruno Manchon JF et al. |
Cytoplasmic sphingosine-1-phosphate pathway modulates neuronal autophagy. |
2015 |
Sci Rep |
pmid:26477494
|
Wang K et al. |
Alkaline Ceramidase 3 Deficiency Results in Purkinje Cell Degeneration and Cerebellar Ataxia Due to Dyshomeostasis of Sphingolipids in the Brain. |
2015 |
PLoS Genet. |
pmid:26474409
|
Johnson CH et al. |
Alterations in Spinal Cord Metabolism during Treatment of Neuropathic Pain. |
2015 |
J Neuroimmune Pharmacol |
pmid:26232265
|
Sutter I et al. |
Plasmalogens of high-density lipoproteins (HDL) are associated with coronary artery disease and anti-apoptotic activity of HDL. |
2015 |
Atherosclerosis |
pmid:26093887
|
Kihara Y et al. |
Lysophospholipid receptors in drug discovery. |
2015 |
Exp. Cell Res. |
pmid:25499971
|
Grenier B et al. |
Dose-dependent effects on sphingoid bases and cytokines in chickens fed diets prepared with fusarium verticillioides culture material containing fumonisins. |
2015 |
Toxins (Basel) |
pmid:25871822
|
Le Bihan O et al. |
Visualization of adherent cell monolayers by cryo-electron microscopy: A snapshot of endothelial adherens junctions. |
2015 |
J. Struct. Biol. |
pmid:26470813
|
Hsu CK et al. |
Mevastatin ameliorates sphingosine 1-phosphate-induced COX-2/PGE2-dependent cell migration via FoxO1 and CREB phosphorylation and translocation. |
2015 |
Br. J. Pharmacol. |
pmid:26359950
|
Höglinger D et al. |
Intracellular sphingosine releases calcium from lysosomes. |
2015 |
Elife |
pmid:26613410
|
Kharel Y et al. |
Sphingosine Kinase 2 Inhibition and Blood Sphingosine 1-Phosphate Levels. |
2015 |
J. Pharmacol. Exp. Ther. |
pmid:26243740
|
Gao XY et al. |
Inhibition of sphingosine-1-phosphate phosphatase 1 promotes cancer cells migration in gastric cancer: Clinical implications. |
2015 |
Oncol. Rep. |
pmid:26239167
|
Malinina L and Brown RE |
Catalytic Mechanism of Eukaryotic Neutral Ceramidase. |
2015 |
Structure |
pmid:26244839
|
Janssen S et al. |
Effect of FTY720-phosphate on the expression of inflammation-associated molecules in astrocytes in vitro. |
2015 |
Mol Med Rep |
pmid:26239526
|
Giese AK et al. |
A novel, highly sensitive and specific biomarker for Niemann-Pick type C1 disease. |
2015 |
Orphanet J Rare Dis |
pmid:26082315
|
Chen MH et al. |
Identification of SPHK1 as a therapeutic target and marker of poor prognosis in cholangiocarcinoma. |
2015 |
Oncotarget |
pmid:26090720
|
Panneer Selvam S et al. |
Binding of the sphingolipid S1P to hTERT stabilizes telomerase at the nuclear periphery by allosterically mimicking protein phosphorylation. |
2015 |
Sci Signal |
pmid:26082434
|
Zhang L et al. |
FTY720 induces autophagy-related apoptosis and necroptosis in human glioblastoma cells. |
2015 |
Toxicol. Lett. |
pmid:25939952
|
Shih HJ et al. |
FTY720 mitigates torsion/detorsion-induced testicular injury in rats. |
2015 |
J. Surg. Res. |
pmid:25862489
|
Laurenzana A et al. |
Endothelial sphingosine kinase/SPNS2 axis is critical for vessel-like formation by human mesoangioblasts. |
2015 |
J. Mol. Med. |
pmid:25952146
|
Rahman MM et al. |
Secretion of PDGF isoforms during osteoclastogenesis and its modulation by anti-osteoclast drugs. |
2015 |
Biochem. Biophys. Res. Commun. |
pmid:25951977
|
Sobel K et al. |
FTY720 Phosphate Activates Sphingosine-1-Phosphate Receptor 2 and Selectively Couples to Gα12/13/Rho/ROCK to Induce Myofibroblast Contraction. |
2015 |
Mol. Pharmacol. |
pmid:25762025
|