sphingosine

sphingosine is a lipid of Sphingolipids (SP) class.

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There are no associated biomedical information in the current reference collection.

Current reference collection contains 26061 references associated with sphingosine in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

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Authors Title Published Journal PubMed Link
Edvardson S et al. Deficiency of the alkaline ceramidase ACER3 manifests in early childhood by progressive leukodystrophy. 2016 J. Med. Genet. pmid:26792856
Li W et al. Sphingosylphosphorylcholine promotes the differentiation of resident Sca-1 positive cardiac stem cells to cardiomyocytes through lipid raft/JNK/STAT3 and β-catenin signaling pathways. 2016 Biochim. Biophys. Acta pmid:27066979
Desai P et al. Dyslipidemia regulates thrombospondin-1-induced vascular smooth muscle cell chemotaxis. 2015 Mol. Cell. Biochem. pmid:26350564
Wilson PC et al. Inhibition of Sphingosine Kinase 1 Ameliorates Angiotensin II-Induced Hypertension and Inhibits Transmembrane Calcium Entry via Store-Operated Calcium Channel. 2015 Mol. Endocrinol. pmid:25871850
Jernigan PL et al. The role of sphingolipids in endothelial barrier function. 2015 Biol. Chem. pmid:25867999
Egom EE et al. The effect of the sphingosine-1-phosphate analogue FTY720 on atrioventricular nodal tissue. 2015 J. Cell. Mol. Med. pmid:25864579
Ohkawa R et al. Possible involvement of sphingomyelin in the regulation of the plasma sphingosine 1-phosphate level in human subjects. 2015 Clin. Biochem. pmid:25863111
Radue EW et al. Correlation between brain volume loss and clinical and MRI outcomes in multiple sclerosis. 2015 Neurology pmid:25632085
Signoriello E et al. Fingolimod efficacy in multiple sclerosis associated with Sjogren syndrome. 2015 Acta Neurol. Scand. pmid:25622658
Kang H et al. The Therapeutic Effects of Human Mesenchymal Stem Cells Primed with Sphingosine-1 Phosphate on Pulmonary Artery Hypertension. 2015 Stem Cells Dev. pmid:25761906
Carrera I et al. A comparative evaluation of a novel vaccine in APP/PS1 mouse models of Alzheimer's disease. 2015 Biomed Res Int pmid:25759822
Ueda N Ceramide-induced apoptosis in renal tubular cells: a role of mitochondria and sphingosine-1-phoshate. 2015 Int J Mol Sci pmid:25751724
Zhao S and Li J Sphingosine-1-phosphate induces the migration of thyroid follicular carcinoma cells through the microRNA-17/PTK6/ERK1/2 pathway. 2015 PLoS ONE pmid:25748447
Issa NP and Hentati A VZV encephalitis that developed in an immunized patient during fingolimod therapy. 2015 Neurology pmid:25416038
Till KJ et al. Expression of functional sphingosine-1 phosphate receptor-1 is reduced by B cell receptor signaling and increased by inhibition of PI3 kinase δ but not SYK or BTK in chronic lymphocytic leukemia cells. 2015 J. Immunol. pmid:25632006
Liu M et al. Uncleaved ApoM signal peptide is required for formation of large ApoM/sphingosine 1-phosphate (S1P)-enriched HDL particles. 2015 J. Biol. Chem. pmid:25627684
O'Sullivan C and Dev KK Galactosylsphingosine (psychosine)-induced demyelination is attenuated by sphingosine 1-phosphate signalling. 2015 J. Cell. Sci. pmid:26359302
Duan J and Merrill AH 1-Deoxysphingolipids Encountered Exogenously and Made de Novo: Dangerous Mysteries inside an Enigma. 2015 J. Biol. Chem. pmid:25947379
Slowik A et al. The sphingosine 1-phosphate receptor agonist FTY720 is neuroprotective after cuprizone-induced CNS demyelination. 2015 Br. J. Pharmacol. pmid:25220526
Kurano M et al. LDL receptor and ApoE are involved in the clearance of ApoM-associated sphingosine 1-phosphate. 2015 J. Biol. Chem. pmid:25505264
Konstantinou D et al. Growth factors mediated differentiation of mesenchymal stem cells to cardiac polymicrotissue using hanging drop and bioreactor. 2015 Cell Biol. Int. pmid:25492631
Frati A et al. Role of sphingosine kinase/S1P axis in ECM remodeling of cardiac cells elicited by relaxin. 2015 Mol. Endocrinol. pmid:25415609
Jaramillo-Gómez J et al. Overexpression of DJ-1 protects against C2-ceramide-induced neuronal death through activation of the PI3K/AKT pathway and inhibition of autophagy. 2015 Neurosci. Lett. pmid:26222260
Landi D et al. Oral fingolimod reduces glutamate-mediated intracortical excitability in relapsing-remitting multiple sclerosis. 2015 Clin Neurophysiol pmid:25022794
Cukkemane N et al. Anti-adherence and bactericidal activity of sphingolipids against Streptococcus mutans. 2015 Eur. J. Oral Sci. pmid:26094809
Burow P et al. Activation of ATP secretion via volume-regulated anion channels by sphingosine-1-phosphate in RAW macrophages. 2015 Pflugers Arch. pmid:24965069
Iwabuchi K et al. Role of Ceramide from Glycosphingolipids and Its Metabolites in Immunological and Inflammatory Responses in Humans. 2015 Mediators Inflamm. pmid:26609196
Mahajan-Thakur S et al. Sphingosine-1-Phosphate and Its Receptors: A Mutual Link between Blood Coagulation and Inflammation. 2015 Mediators Inflamm. pmid:26604433
Barnawi J et al. Potential Link between the Sphingosine-1-Phosphate (S1P) System and Defective Alveolar Macrophage Phagocytic Function in Chronic Obstructive Pulmonary Disease (COPD). 2015 PLoS ONE pmid:26485657
Moruno Manchon JF et al. Cytoplasmic sphingosine-1-phosphate pathway modulates neuronal autophagy. 2015 Sci Rep pmid:26477494
Wang K et al. Alkaline Ceramidase 3 Deficiency Results in Purkinje Cell Degeneration and Cerebellar Ataxia Due to Dyshomeostasis of Sphingolipids in the Brain. 2015 PLoS Genet. pmid:26474409
Johnson CH et al. Alterations in Spinal Cord Metabolism during Treatment of Neuropathic Pain. 2015 J Neuroimmune Pharmacol pmid:26232265
Sutter I et al. Plasmalogens of high-density lipoproteins (HDL) are associated with coronary artery disease and anti-apoptotic activity of HDL. 2015 Atherosclerosis pmid:26093887
Kihara Y et al. Lysophospholipid receptors in drug discovery. 2015 Exp. Cell Res. pmid:25499971
Grenier B et al. Dose-dependent effects on sphingoid bases and cytokines in chickens fed diets prepared with fusarium verticillioides culture material containing fumonisins. 2015 Toxins (Basel) pmid:25871822
Le Bihan O et al. Visualization of adherent cell monolayers by cryo-electron microscopy: A snapshot of endothelial adherens junctions. 2015 J. Struct. Biol. pmid:26470813
Hsu CK et al. Mevastatin ameliorates sphingosine 1-phosphate-induced COX-2/PGE2-dependent cell migration via FoxO1 and CREB phosphorylation and translocation. 2015 Br. J. Pharmacol. pmid:26359950
Höglinger D et al. Intracellular sphingosine releases calcium from lysosomes. 2015 Elife pmid:26613410
Kharel Y et al. Sphingosine Kinase 2 Inhibition and Blood Sphingosine 1-Phosphate Levels. 2015 J. Pharmacol. Exp. Ther. pmid:26243740
Gao XY et al. Inhibition of sphingosine-1-phosphate phosphatase 1 promotes cancer cells migration in gastric cancer: Clinical implications. 2015 Oncol. Rep. pmid:26239167
Malinina L and Brown RE Catalytic Mechanism of Eukaryotic Neutral Ceramidase. 2015 Structure pmid:26244839
Janssen S et al. Effect of FTY720-phosphate on the expression of inflammation-associated molecules in astrocytes in vitro. 2015 Mol Med Rep pmid:26239526
Giese AK et al. A novel, highly sensitive and specific biomarker for Niemann-Pick type C1 disease. 2015 Orphanet J Rare Dis pmid:26082315
Chen MH et al. Identification of SPHK1 as a therapeutic target and marker of poor prognosis in cholangiocarcinoma. 2015 Oncotarget pmid:26090720
Panneer Selvam S et al. Binding of the sphingolipid S1P to hTERT stabilizes telomerase at the nuclear periphery by allosterically mimicking protein phosphorylation. 2015 Sci Signal pmid:26082434
Zhang L et al. FTY720 induces autophagy-related apoptosis and necroptosis in human glioblastoma cells. 2015 Toxicol. Lett. pmid:25939952
Shih HJ et al. FTY720 mitigates torsion/detorsion-induced testicular injury in rats. 2015 J. Surg. Res. pmid:25862489
Laurenzana A et al. Endothelial sphingosine kinase/SPNS2 axis is critical for vessel-like formation by human mesoangioblasts. 2015 J. Mol. Med. pmid:25952146
Rahman MM et al. Secretion of PDGF isoforms during osteoclastogenesis and its modulation by anti-osteoclast drugs. 2015 Biochem. Biophys. Res. Commun. pmid:25951977
Sobel K et al. FTY720 Phosphate Activates Sphingosine-1-Phosphate Receptor 2 and Selectively Couples to Gα12/13/Rho/ROCK to Induce Myofibroblast Contraction. 2015 Mol. Pharmacol. pmid:25762025