| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Mathes C et al. | Calcium release-activated calcium current (ICRAC) is a direct target for sphingosine. | 1998 | J. Biol. Chem. | pmid:9737958 |
| Matsuda T et al. | Caspase requirement for the apoptotic death of WR19L-induced by FTY720. | 1998 | Transplant. Proc. | pmid:9723502 |
| Kleuser B et al. | 1Alpha,25-dihydroxyvitamin D3 inhibits programmed cell death in HL-60 cells by activation of sphingosine kinase. | 1998 | Cancer Res. | pmid:9581819 |
| Nakajima H et al. | FTY720 inhibits the mRNA expression of intragraft cytotoxic molecules, leading to cardiac allograft survival. | 1998 | Transplant. Proc. | pmid:9723446 |
| Kahan BD | FTY720: a new immunosuppressive agent with novel mechanism(s) of action. | 1998 | Transplant. Proc. | pmid:9723444 |
| Troncoso P and Kahan BD | Preclinical evaluation of a new immunosuppressive agent, FTY720. | 1998 | Clin. Biochem. | pmid:9721436 |
| Riboni L et al. | Metabolic fate of exogenous sphingosine in neuroblastoma neuro2A cells. Dose-dependence and biological effects. | 1998 | Ann. N. Y. Acad. Sci. | pmid:9668342 |
| Fukuda Y et al. | Effect of FTY720 on immunoregulation in concordant xenotransplantation. | 1998 | Transpl. Int. | pmid:9665039 |
| Searl TJ and Silinsky EM | Increases in acetylcholine release produced by phorbol esters are not mediated by protein kinase C at motor nerve endings. | 1998 | J. Pharmacol. Exp. Ther. | pmid:9536018 |
| Edsall LC et al. | N,N-Dimethylsphingosine is a potent competitive inhibitor of sphingosine kinase but not of protein kinase C: modulation of cellular levels of sphingosine 1-phosphate and ceramide. | 1998 | Biochemistry | pmid:9737868 |
| Muramatsu K et al. | A new immunosuppressant, FTY720, prolongs limb allograft survival in rats. | 1998 | Ann Plast Surg | pmid:9495465 |
| Spiegel S et al. | Sphingosine-1-phosphate in cell growth and cell death. | 1998 | Ann. N. Y. Acad. Sci. | pmid:9668339 |
| Igarashi Y | Sphingosine-1-phosphate as an intercellular signaling molecule. | 1998 | Ann. N. Y. Acad. Sci. | pmid:9668340 |
| Stam JC et al. | Invasion of T-lymphoma cells: cooperation between Rho family GTPases and lysophospholipid receptor signaling. | 1998 | EMBO J. | pmid:9670021 |
| Himmel HM et al. | Guanine nucleotide-sensitive inhibition of L-type Ca2+ current by lysosphingolipids in RINm5F insulinoma cells. | 1998 | Mol. Pharmacol. | pmid:9584212 |
| Tas PW and Koschel K | Sphingosine-1-phosphate induces a Ca2+ signal in primary rat astrocytes and a Ca2+ signal and shape changes in C6 rat glioma cells. | 1998 | J. Neurosci. Res. | pmid:9589387 |
| Skrzypek MS et al. | Inhibition of amino acid transport by sphingoid long chain bases in Saccharomyces cerevisiae. | 1998 | J. Biol. Chem. | pmid:9446592 |
| Bodennec J et al. | Phytosphingosine biosynthesis differs from sphingosine in fish leukocytes and involves a transfer of methyl groups from [3H-methyl]methionine precursor. | 1998 | Biochem. Biophys. Res. Commun. | pmid:9735337 |
| Orlati S et al. | Sphingosylphosphorylcholine and sphingosine-1-phosphate mobilize cytosolic calcium through different mechanisms in human airway epithelial cells. | 1998 | Cell Calcium | pmid:9924630 |
| Igarashi Y and Yatomi Y | Sphingosine 1-phosphate is a blood constituent released from activated platelets, possibly playing a variety of physiological and pathophysiological roles. | 1998 | Acta Biochim. Pol. | pmid:9821862 |
| Jarvis WD et al. | Evidence for involvement of mitogen-activated protein kinase, rather than stress-activated protein kinase, in potentiation of 1-beta-D-arabinofuranosylcytosine-induced apoptosis by interruption of protein kinase C signaling. | 1998 | Mol. Pharmacol. | pmid:9804619 |
| Orlati S et al. | Intracellular calcium mobilization and phospholipid degradation in sphingosylphosphorylcholine-stimulated human airway epithelial cells. | 1998 | Biochem. J. | pmid:9729473 |
| Reggiori F and Conzelmann A | Biosynthesis of inositol phosphoceramides and remodeling of glycosylphosphatidylinositol anchors in Saccharomyces cerevisiae are mediated by different enzymes. | 1998 | J. Biol. Chem. | pmid:9804825 |
| Sakakura C et al. | Selectivity of sphingosine-induced apoptosis. Lack of activity of DL-erythyro-dihydrosphingosine. | 1998 | Biochem. Biophys. Res. Commun. | pmid:9618297 |
| Collins TF et al. | Effects of fumonisin B1 in pregnant rats. | 1998 | Food Chem. Toxicol. | pmid:9662415 |
| Ping SE and Barrett GL | Ceramide can induce cell death in sensory neurons, whereas ceramide analogues and sphingosine promote survival. | 1998 | J. Neurosci. Res. | pmid:9788279 |
| Yorek MA et al. | Opposing effects of tumour necrosis factor alpha and hyperosmolarity on Na+/myo-inositol co-transporter mRNA levels and myo-inositol accumulation by 3T3-L1 adipocytes. | 1998 | Biochem. J. | pmid:9820807 |
| Cuvillier O et al. | Sphingosine 1-phosphate inhibits activation of caspases that cleave poly(ADP-ribose) polymerase and lamins during Fas- and ceramide-mediated apoptosis in Jurkat T lymphocytes. | 1998 | J. Biol. Chem. | pmid:9446602 |
| Sakai T et al. | Effects of alpha- and beta-galactosylated C2-ceramides on the immune system. | 1998 | J. Med. Chem. | pmid:9484513 |
| Chiba K et al. | FTY720, a novel immunosuppressant, induces sequestration of circulating mature lymphocytes by acceleration of lymphocyte homing in rats. I. FTY720 selectively decreases the number of circulating mature lymphocytes by acceleration of lymphocyte homing. | 1998 | J. Immunol. | pmid:9590253 |
| Simon CG and Gear AR | Membrane-destabilizing properties of C2-ceramide may be responsible for its ability to inhibit platelet aggregation. | 1998 | Biochemistry | pmid:9485333 |
| Monney L et al. | Role of an acidic compartment in tumor-necrosis-factor-alpha-induced production of ceramide, activation of caspase-3 and apoptosis. | 1998 | Eur. J. Biochem. | pmid:9492297 |
| Grosman N | Influence of probes for calcium-calmodulin and protein kinase C signalling on the plasma membrane Ca2+-ATPase activity of rat synaptosomes and leukocyte membranes. | 1998 | Immunopharmacology | pmid:9826030 |
| Yanagawa Y et al. | FTY720, a novel immunosuppressant, induces sequestration of circulating mature lymphocytes by acceleration of lymphocyte homing in rats. II. FTY720 prolongs skin allograft survival by decreasing T cell infiltration into grafts but not cytokine production in vivo. | 1998 | J. Immunol. | pmid:9605152 |
| Wang ME et al. | Immunosuppressive effects of FTY720 alone or in combination with cyclosporine and/or sirolimus. | 1998 | Transplantation | pmid:9565092 |
| Lee SC et al. | The naturally occurring PKC inhibitor sphingosine and tumor promoter phorbol ester potentially induce tyrosine phosphorylation/activation of oncogenic proline-directed protein kinase FA/GSK-3alpha in a common signalling pathway. | 1998 | J. Protein Chem. | pmid:9491924 |
| Harada-Shiba M et al. | Oxidized low density lipoprotein induces apoptosis in cultured human umbilical vein endothelial cells by common and unique mechanisms. | 1998 | J. Biol. Chem. | pmid:9545302 |
| Foghi A et al. | Fas-induced apoptosis in rat thecal/interstitial cells signals through sphingomyelin-ceramide pathway. | 1998 | Endocrinology | pmid:9528992 |
| Takeda H et al. | Sphingomyelinase and ceramide inhibit formation of F-actin ring in and bone resorption by rabbit mature osteoclasts. | 1998 | FEBS Lett. | pmid:9490019 |
| Flores I et al. | Dual role of ceramide in the control of apoptosis following IL-2 withdrawal. | 1998 | J. Immunol. | pmid:9531315 |
| Veldman RJ et al. | Metabolism and apoptotic properties of elevated ceramide in HT29rev cells. | 1998 | Biochem. J. | pmid:9531498 |
| Nagiec MM et al. | The LCB4 (YOR171c) and LCB5 (YLR260w) genes of Saccharomyces encode sphingoid long chain base kinases. | 1998 | J. Biol. Chem. | pmid:9677363 |
| Lawler JF et al. | Tumor necrosis factor-alpha stimulates the maturation of sterol regulatory element binding protein-1 in human hepatocytes through the action of neutral sphingomyelinase. | 1998 | J. Biol. Chem. | pmid:9478955 |
| Van Brocklyn JR et al. | Dual actions of sphingosine-1-phosphate: extracellular through the Gi-coupled receptor Edg-1 and intracellular to regulate proliferation and survival. | 1998 | J. Cell Biol. | pmid:9660876 |
| Reunanen N et al. | Enhancement of fibroblast collagenase (matrix metalloproteinase-1) gene expression by ceramide is mediated by extracellular signal-regulated and stress-activated protein kinase pathways. | 1998 | J. Biol. Chem. | pmid:9478967 |
| Mandala SM et al. | Sphingoid base 1-phosphate phosphatase: a key regulator of sphingolipid metabolism and stress response. | 1998 | Proc. Natl. Acad. Sci. U.S.A. | pmid:9419344 |
| Pfau JC et al. | A comparison of the effects of lipopolysaccharide and ceramide on arachidonic acid metabolism in THP-1 monocytic cells. | 1998 | Cell. Immunol. | pmid:9665757 |
| Guo C et al. | Differential stimulation of proline-rich tyrosine kinase 2 and mitogen-activated protein kinase by sphingosine 1-phosphate. | 1998 | Eur. J. Biochem. | pmid:9826186 |
| Kishida E et al. | Distinctive inhibitory activity of docosahexaenoic acid against sphingosine-induced apoptosis. | 1998 | Biochim. Biophys. Acta | pmid:9555103 |
| Xia P et al. | Tumor necrosis factor-alpha induces adhesion molecule expression through the sphingosine kinase pathway. | 1998 | Proc. Natl. Acad. Sci. U.S.A. | pmid:9826677 |
| Vento R et al. | Induction of programmed cell death in human retinoblastoma Y79 cells by C2-ceramide. | 1998 | Mol. Cell. Biochem. | pmid:9746206 |
| Rossner S et al. | p75 and TrkA receptor signaling independently regulate amyloid precursor protein mRNA expression, isoform composition, and protein secretion in PC12 cells. | 1998 | J. Neurochem. | pmid:9681467 |
| Cartus T et al. | Distribution of protein phosphatases type 1 and 2A in RINm5F cells. | 1998 | Regul. Pept. | pmid:9809799 |
| Mizushima N et al. | Ceramide, a mediator of interleukin 1, tumour necrosis factor alpha, as well as Fas receptor signalling, induces apoptosis of rheumatoid arthritis synovial cells. | 1998 | Ann. Rheum. Dis. | pmid:9797556 |
| Ji L et al. | Effects of endoglycoceramidase or D-threo-1-phenyl-2-decanoylamino-3-morpholino-1-propanol on glucose uptake, glycolysis, and mitochondrial respiration in HL60 cells. | 1998 | Arch. Biochem. Biophys. | pmid:9799567 |
| Koolpe M et al. | Adenosine 5'-triphosphate, uridine 5'-triphosphate, bradykinin, and lysophosphatidic acid induce different patterns of calcium responses by human articular chondrocytes. | 1998 | J. Orthop. Res. | pmid:9621896 |
| Meyer zu Heringdorf D et al. | Sphingosine kinase-mediated Ca2+ signalling by G-protein-coupled receptors. | 1998 | EMBO J. | pmid:9582276 |
| Lakics V and Vogel SN | Lipopolysaccharide and ceramide use divergent signaling pathways to induce cell death in murine macrophages. | 1998 | J. Immunol. | pmid:9725248 |
| Schmelz EM et al. | Induction of apoptosis by fumonisin B1 in HT29 cells is mediated by the accumulation of endogenous free sphingoid bases. | 1998 | Toxicol. Appl. Pharmacol. | pmid:9473533 |
| Hama-Inaba H et al. | Radio-sensitive murine thymoma cell line 3SB: characterization of its apoptosis-resistant variants induced by repeated X-irradiation. | 1998 | Mutat. Res. | pmid:9726009 |
| Durrieu F et al. | Caspase activation is an early event in anthracycline-induced apoptosis and allows detection of apoptotic cells before they are ingested by phagocytes. | 1998 | Exp. Cell Res. | pmid:9596989 |
| Ghahremani M et al. | Activation of Fas ligand/receptor system kills ovarian cancer cell lines by an apoptotic mechanism. | 1998 | Gynecol. Oncol. | pmid:9740705 |
| Centeno F et al. | Partial lithium-associated protection against apoptosis induced by C2-ceramide in cerebellar granule neurons. | 1998 | Neuroreport | pmid:9926873 |
| Yano M et al. | Quantitative analysis of ceramide molecular species by high performance liquid chromatography. | 1998 | J. Lipid Res. | pmid:9788256 |
| Xu M et al. | FTY720 compares with FK 506 as rescue therapy in rat heterotopic cardiac transplantation. | 1998 | Transplant. Proc. | pmid:9723447 |
| Johns DG et al. | The role of the endothelium in ceramide-induced vasodilation. | 1998 | Eur. J. Pharmacol. | pmid:9671089 |
| Ragg SJ et al. | The mitogen-activated protein kinase pathway inhibits ceramide-induced terminal differentiation of a human monoblastic leukemia cell line, U937. | 1998 | J. Immunol. | pmid:9686602 |
| Oyama Y et al. | Cytotoxic actions of FTY720, a novel immunosuppressant, on thymocytes and brain neurons dissociated from the rat. | 1998 | Jpn. J. Pharmacol. | pmid:9623716 |
| Ichinose Y et al. | Apoptosis induction in synovial fibroblasts by ceramide: in vitro and in vivo effects. | 1998 | J. Lab. Clin. Med. | pmid:9605105 |
| Canova C et al. | Epigenetic control of programmed cell death: inhibition by 5-azacytidine of 1,25-dihydroxyvitamin D3-induced programmed cell death in C6.9 glioma cells. | 1998 | Mech. Ageing Dev. | pmid:9593321 |
| Noh SJ et al. | Different signaling pathway between sphingosine-1-phosphate and lysophosphatidic acid in Xenopus oocytes: functional coupling of the sphingosine-1-phosphate receptor to PLC-xbeta in Xenopus oocytes. | 1998 | J. Cell. Physiol. | pmid:9648929 |
| Auzenne E et al. | Cytotoxic effects of sphingolipids as single or multi-modality agents on human melanoma and soft tissue sarcoma in vitro. | 1998 | Melanoma Res. | pmid:9664144 |
| Tsunoda M et al. | Early fumonisin B1 toxicity in relation to disrupted sphingolipid metabolism in male BALB/c mice. | 1998 | J. Biochem. Mol. Toxicol. | pmid:9664234 |
| Humpf HU et al. | Acylation of naturally occurring and synthetic 1-deoxysphinganines by ceramide synthase. Formation of N-palmitoyl-aminopentol produces a toxic metabolite of hydrolyzed fumonisin, AP1, and a new category of ceramide synthase inhibitor. | 1998 | J. Biol. Chem. | pmid:9668088 |
| van der Westhuizen L et al. | Inhibition of sphingolipid biosynthesis in rat primary hepatocyte cultures by fumonisin B1 and other structurally related compounds. | 1998 | Food Chem. Toxicol. | pmid:9674957 |
| Lee MJ et al. | Sphingosine-1-phosphate as a ligand for the G protein-coupled receptor EDG-1. | 1998 | Science | pmid:9488656 |
| Patel M | Inhibition of neuronal apoptosis by a metalloporphyrin superoxide dismutase mimic. | 1998 | J. Neurochem. | pmid:9721731 |
| van Echten-Deckert G et al. | Phosphorylated cis-4-methylsphingosine mimics the mitogenic effect of sphingosine-1-phosphate in Swiss 3T3 fibroblasts. | 1998 | J. Biol. Chem. | pmid:9722598 |
| Zager RA et al. | Ceramide accumulation during oxidant renal tubular injury: mechanisms and potential consequences. | 1998 | J. Am. Soc. Nephrol. | pmid:9727376 |
| Ayar A et al. | Mobilization of intracellular calcium by intracellular flash photolysis of caged dihydrosphingosine in cultured neonatal rat sensory neurones. | 1998 | Acta Biochim. Pol. | pmid:9821863 |
| Stepkowski SM et al. | Synergistic interaction of FTY720 with cyclosporine or sirolimus to prolong heart allograft survival. | 1998 | Transplant. Proc. | pmid:9723445 |
| Piperno M et al. | Osteoarthritic cartilage fibrillation is associated with a decrease in chondrocyte adhesion to fibronectin. | 1998 | Osteoarthr. Cartil. | pmid:10343772 |
| Saito M et al. | The semisynthetic glycosphingolipid LIGA20 potently protects neurons against apoptosis. | 1998 | Ann. N. Y. Acad. Sci. | pmid:9668359 |
| Kiuchi M et al. | Synthesis and biological evaluation of 2,2-disubstituted 2-aminoethanols: analogues of FTY720. | 1998 | Bioorg. Med. Chem. Lett. | pmid:9925439 |
| Melendez A et al. | FcgammaRI coupling to phospholipase D initiates sphingosine kinase-mediated calcium mobilization and vesicular trafficking. | 1998 | J. Biol. Chem. | pmid:9545263 |
| Yanagawa Y et al. | FTY720, a novel immunosuppressant, induces sequestration of circulating mature lymphocytes by acceleration of lymphocyte homing in rats, III. Increase in frequency of CD62L-positive T cells in Peyer's patches by FTY720-induced lymphocyte homing. | 1998 | Immunology | pmid:9893050 |
| Wakita H et al. | Sphingosylphosphorylcholine stimulates proliferation and upregulates cell surface-associated plasminogen activator activity in cultured human keratinocytes. | 1998 | J. Invest. Dermatol. | pmid:9506444 |
| Soeda S et al. | Tumor necrosis factor-alpha-induced release of plasminogen activator inhibitor-1 from human umbilical vein endothelial cells: involvement of intracellular ceramide signaling event. | 1998 | Biochim. Biophys. Acta | pmid:9824663 |
| Chigorno V et al. | Human fibroblasts in culture metabolize differently exogenous G(M3) ganglioside species containing C18 and C20 sphingosine. | 1998 | Acta Biochim. Pol. | pmid:9821869 |
| Hamada K et al. | Involvement of Mac-1-mediated adherence and sphingosine 1-phosphate in survival of phorbol ester-treated U937 cells. | 1998 | Biochem. Biophys. Res. Commun. | pmid:9535736 |
| Yan H et al. | Immunosuppressive effect of FTY 720 on autoimmune diabetes models. | 1998 | Transplant. Proc. | pmid:9838514 |
| Hisano N et al. | Quantification of sphingosine derivatives in human platelets: inducible formation of free sphingosine. | 1998 | J. Biochem. | pmid:9538201 |
| Suzuki K et al. | Immunosuppressive effect of FTY 720 on rat pancreas allograft. | 1998 | Transplant. Proc. | pmid:9838506 |
| Nyberg L et al. | Digestion of ceramide by human milk bile salt-stimulated lipase. | 1998 | J. Pediatr. Gastroenterol. Nutr. | pmid:9822324 |
| Meyer zu Heringdorf D et al. | Discrimination between plasma membrane and intracellular target sites of sphingosylphosphorylcholine. | 1998 | Eur. J. Pharmacol. | pmid:9726638 |
| Sánchez C et al. | Involvement of sphingomyelin hydrolysis and the mitogen-activated protein kinase cascade in the Delta9-tetrahydrocannabinol-induced stimulation of glucose metabolism in primary astrocytes. | 1998 | Mol. Pharmacol. | pmid:9804618 |
| Marks N et al. | Activation of caspase-3 and apoptosis in cerebellar granule cells. | 1998 | J. Neurosci. Res. | pmid:9590441 |
| Riboni L et al. | The effects of exogenous sphingosine on Neuro2a cells are strictly related to the overall capacity of cells to metabolize sphingosine. | 1998 | J. Biochem. | pmid:9792911 |
| Asfaw B et al. | Degradation of blood group A glycolipid A-6-2 by normal and mutant human skin fibroblasts. | 1998 | J. Lipid Res. | pmid:9741689 |
| RodrÃguez-Fernández JL and Rozengurt E | Bombesin, vasopressin, lysophosphatidic acid, and sphingosylphosphorylcholine induce focal adhesion kinase activation in intact Swiss 3T3 cells. | 1998 | J. Biol. Chem. | pmid:9668122 |
sphingosine
sphingosine is a lipid of Sphingolipids (SP) class.
Cross Reference
