| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Kennedy SD et al. | Measurement of in vitro P-selectin expression by flow cytometry. | 1997 | Am. J. Clin. Pathol. | pmid:8980375 |
| Alkan S et al. | Survival role of protein kinase C (PKC) in chronic lymphocytic leukemia and determination of isoform expression pattern and genes altered by PKC inhibition. | 2005 | Am. J. Hematol. | pmid:15929099 |
| Jenkins RW et al. | Evaluation of the role of secretory sphingomyelinase and bioactive sphingolipids as biomarkers in hemophagocytic lymphohistiocytosis. | 2013 | Am. J. Hematol. | pmid:23828274 |
| Santos-Cortez RL et al. | Autosomal-Recessive Hearing Impairment Due to Rare Missense Variants within S1PR2. | 2016 | Am. J. Hum. Genet. | pmid:26805784 |
| Grabowski GA et al. | Gaucher disease types 1, 2, and 3: differential mutations of the acid beta-glucosidase active site identified with conduritol B epoxide derivatives and sphingosine. | 1985 | Am. J. Hum. Genet. | pmid:4003396 |
| Sis B et al. | Antibody-mediated rejection with a striking interstitial monocyte/macrophage infiltration in a renal allograft under FTY720 treatment. | 2008 | Am. J. Kidney Dis. | pmid:18155542 |
| Kim M et al. | Isoflurane protects human kidney proximal tubule cells against necrosis via sphingosine kinase and sphingosine-1-phosphate generation. | 2010 | Am. J. Nephrol. | pmid:20234131 |
| Sandhu KS et al. | Regional heterogeneity in expression of the sphingosine-1-phosphate pathway in the female rat lower urinary tract. | 2009 | Am. J. Obstet. Gynecol. | pmid:19254791 |
| Miron VE et al. | Fingolimod (FTY720) enhances remyelination following demyelination of organotypic cerebellar slices. | 2010 | Am. J. Pathol. | pmid:20413685 |
| Armstrong SM et al. | Co-regulation of transcellular and paracellular leak across microvascular endothelium by dynamin and Rac. | 2012 | Am. J. Pathol. | pmid:22203054 |
| Rau CR et al. | Anti-inflammatory effects of FTY720 do not prevent neuronal cell loss in a rat model of optic neuritis. | 2011 | Am. J. Pathol. | pmid:21406175 |
| Wang R et al. | Hepatic Stellate Cell Selective Disruption of Dynamin-2 GTPase Increases Murine Fibrogenesis through Up-Regulation of Sphingosine-1 Phosphate-Induced Cell Migration. | 2017 | Am. J. Pathol. | pmid:27840081 |
| Straub AC et al. | Arsenic requires sphingosine-1-phosphate type 1 receptors to induce angiogenic genes and endothelial cell remodeling. | 2009 | Am. J. Pathol. | pmid:19349368 |
| Harijith A et al. | Sphingosine kinase 1 deficiency confers protection against hyperoxia-induced bronchopulmonary dysplasia in a murine model: role of S1P signaling and Nox proteins. | 2013 | Am. J. Pathol. | pmid:23933064 |
| Li C et al. | Involvement of sphingosine 1-phosphate (SIP)/S1P3 signaling in cholestasis-induced liver fibrosis. | 2009 | Am. J. Pathol. | pmid:19729475 |
| Shimizu Y et al. | Potentials of the circulating pruritogenic mediator lysophosphatidic acid in development of allergic skin inflammation in mice: role of blood cell-associated lysophospholipase D activity of autotaxin. | 2014 | Am. J. Pathol. | pmid:24641902 |
| Xiu L et al. | Intracellular sphingosine 1-phosphate contributes to collagen expression of hepatic myofibroblasts in human liver fibrosis independent of its receptors. | 2015 | Am. J. Pathol. | pmid:25432063 |
| Ishimaru N et al. | CCR7 with S1P1 signaling through AP-1 for migration of Foxp3+ regulatory T-cells controls autoimmune exocrinopathy. | 2012 | Am. J. Pathol. | pmid:22067914 |
| Suomalainen L et al. | Sphingosine-1-phosphate inhibits nuclear factor kappaB activation and germ cell apoptosis in the human testis independently of its receptors. | 2005 | Am. J. Pathol. | pmid:15743789 |
| Krishna SM et al. | Fenofibrate increases high-density lipoprotein and sphingosine 1 phosphate concentrations limiting abdominal aortic aneurysm progression in a mouse model. | 2012 | Am. J. Pathol. | pmid:22698985 |
| Sugita K et al. | FTY720 regulates bone marrow egress of eosinophils and modulates late-phase skin reaction in mice. | 2010 | Am. J. Pathol. | pmid:20802177 |
| Keller CD et al. | Immunomodulator FTY720 induces myofibroblast differentiation via the lysophospholipid receptor S1P3 and Smad3 signaling. | 2007 | Am. J. Pathol. | pmid:17200201 |
| Bi Y et al. | Sphingosine-1-phosphate mediates a reciprocal signaling pathway between stellate cells and cancer cells that promotes pancreatic cancer growth. | 2014 | Am. J. Pathol. | pmid:25111230 |
| Haghikia A and Gold R | The impact of fingolimod (FTY720) in neuroimmunologic diseases: mechanisms beyond immunomodulation. | 2010 | Am. J. Pathol. | pmid:20395429 |
| Norimatsu Y et al. | FTY720 improves functional recovery after spinal cord injury by primarily nonimmunomodulatory mechanisms. | 2012 | Am. J. Pathol. | pmid:22417787 |
| Bielawska AE et al. | Ceramide is involved in triggering of cardiomyocyte apoptosis induced by ischemia and reperfusion. | 1997 | Am. J. Pathol. | pmid:9358751 |
| Sun WY et al. | Rapid histamine-induced neutrophil recruitment is sphingosine kinase-1 dependent. | 2012 | Am. J. Pathol. | pmid:22322303 |
| Copland DA et al. | Therapeutic dosing of fingolimod (FTY720) prevents cell infiltration, rapidly suppresses ocular inflammation, and maintains the blood-ocular barrier. | 2012 | Am. J. Pathol. | pmid:22119714 |
| Watson C et al. | High expression of sphingosine 1-phosphate receptors, S1P1 and S1P3, sphingosine kinase 1, and extracellular signal-regulated kinase-1/2 is associated with development of tamoxifen resistance in estrogen receptor-positive breast cancer patients. | 2010 | Am. J. Pathol. | pmid:20889557 |
| Mori H et al. | Smad3 deficiency leads to mandibular condyle degradation via the sphingosine 1-phosphate (S1P)/S1P3 signaling axis. | 2015 | Am. J. Pathol. | pmid:26272361 |
| Simonaro CM et al. | Mechanism of glycosaminoglycan-mediated bone and joint disease: implications for the mucopolysaccharidoses and other connective tissue diseases. | 2008 | Am. J. Pathol. | pmid:18079441 |
| Miron VE et al. | Cyclical and dose-dependent responses of adult human mature oligodendrocytes to fingolimod. | 2008 | Am. J. Pathol. | pmid:18772343 |
| Kai H et al. | Involvement of protein kinase C in mucus secretion by hamster tracheal epithelial cells in culture. | 1994 | Am. J. Physiol. | pmid:7977763 |
| Needleman DH et al. | Modulation of skeletal muscle Ca2(+)-release channel activity by sphingosine. | 1997 | Am. J. Physiol. | pmid:9176136 |
| Kimura T et al. | Inhibition of TSH-induced hydrogen peroxide production by TNF-alpha through a sphingomyelinase signaling pathway. | 1997 | Am. J. Physiol. | pmid:9316456 |
| Im DS et al. | Characterization of sphingosine 1-phosphate-induced actions and its signaling pathways in rat hepatocytes. | 1997 | Am. J. Physiol. | pmid:9176218 |
| Murohara T et al. | Myocardial and endothelial protection by TMS in ischemia-reperfusion injury. | 1995 | Am. J. Physiol. | pmid:7544541 |
| Wallert MA and Fröhlich O | Alpha 1-adrenergic stimulation of Na-H exchange in cardiac myocytes. | 1992 | Am. J. Physiol. | pmid:1359793 |
| Hartzell HC and Rinderknecht A | Calphostin C, a widely used protein kinase C inhibitor, directly and potently blocks L-type Ca channels. | 1996 | Am. J. Physiol. | pmid:8967428 |
| Sachs JR | Soluble polycations and cationic amphiphiles inhibit volume-sensitive K-Cl cotransport in human red cell ghosts. | 1994 | Am. J. Physiol. | pmid:8178972 |
| Ling BN and Eaton DC | Effects of luminal Na+ on single Na+ channels in A6 cells, a regulatory role for protein kinase C. | 1989 | Am. J. Physiol. | pmid:2544105 |
| Jacobs LS and Kester M | Sphingolipids as mediators of effects of platelet-derived growth factor in vascular smooth muscle cells. | 1993 | Am. J. Physiol. | pmid:8214030 |
| Murray MA et al. | Effect of protein kinase C inhibitors on endothelin- and vasopressin-induced constriction of the rat basilar artery. | 1992 | Am. J. Physiol. | pmid:1481891 |
| Ware JA et al. | Response of aequorin-loaded platelets to activators of protein kinase C. | 1989 | Am. J. Physiol. | pmid:2912135 |
| Bertorello A and Aperia A | Na+-K+-ATPase is an effector protein for protein kinase C in renal proximal tubule cells. | 1989 | Am. J. Physiol. | pmid:2537029 |
| Paul A et al. | Regulation of secretion in cultured tracheal serous cells by protein kinases A and C. | 1991 | Am. J. Physiol. | pmid:1651665 |
| Tolan D et al. | Sphingosine prevents diacylglycerol signaling to mitogen-activated protein kinase in airway smooth muscle. | 1997 | Am. J. Physiol. | pmid:9316414 |
| Worrell RT and Frizzell RA | CaMKII mediates stimulation of chloride conductance by calcium in T84 cells. | 1991 | Am. J. Physiol. | pmid:1708204 |
| HECHT E et al. | Sphingosine as inhibitor of prothrombin activation with thromboplastin or with threone. | 1957 | Am. J. Physiol. | pmid:13424718 |
| SADHU DP | Influence of lactose on the transglycosidation of sphingosine base in the rat brain. | 1953 | Am. J. Physiol. | pmid:13114397 |
| Fukuda K et al. | Histamine H1-receptor-mediated keratan sulfate production in rabbit chondrocytes: involvement of protein kinase C. | 1991 | Am. J. Physiol. | pmid:1887868 |
| Zoukhri D et al. | Phorbol ester-stimulated exocytosis in lacrimal gland: PKC might not be the sole effector. | 1993 | Am. J. Physiol. | pmid:8386449 |
| Mitsuka M and Berk BC | Long-term regulation of Na(+)-H+ exchange in vascular smooth muscle cells: role of protein kinase C. | 1991 | Am. J. Physiol. | pmid:1848402 |
| Durieux ME et al. | Responses to sphingosine-1-phosphate in X. laevis oocytes: similarities with lysophosphatidic acid signaling. | 1993 | Am. J. Physiol. | pmid:7684565 |
| Satoh T and Endou H | Inhibitory effect of phorbol ester on sodium transport in frog urinary bladder. | 1990 | Am. J. Physiol. | pmid:2168677 |
| Luo H et al. | Participation of protein kinase C in desensitization to bradykinin and to carbachol in MDCK cells. | 1992 | Am. J. Physiol. | pmid:1313646 |
| Yasui K and Palade P | Sphingolipid actions on sodium and calcium currents of rat ventricular myocytes. | 1996 | Am. J. Physiol. | pmid:8779930 |
| Bitar KN and Yamada H | Modulation of smooth muscle contraction by sphingosylphosphorylcholine. | 1995 | Am. J. Physiol. | pmid:7573447 |
| Törnquist K | Sphingosine 1-phosphate stimulates Na+/H+ exchange in thyroid FRTL-5 cells. | 1997 | Am. J. Physiol. | pmid:9124507 |
| Kachintorn U et al. | Dual effects of a phorbol ester on calcium-dependent chloride secretion by T84 epithelial cells. | 1992 | Am. J. Physiol. | pmid:1733229 |
| Jeng YJ et al. | Progesterone-induced sphingosine kinase-1 expression in the rat uterus during pregnancy and signaling consequences. | 2007 | Am. J. Physiol. Endocrinol. Metab. | pmid:17164439 |
| Yang G et al. | Central role of ceramide biosynthesis in body weight regulation, energy metabolism, and the metabolic syndrome. | 2009 | Am. J. Physiol. Endocrinol. Metab. | pmid:19435851 |
| Koscielny A et al. | The role of lymphoid tissue in the attenuation of the postoperative ileus. | 2013 | Am. J. Physiol. Gastrointest. Liver Physiol. | pmid:23238935 |
| Bitar KN | HSP27 phosphorylation and interaction with actin-myosin in smooth muscle contraction. | 2002 | Am. J. Physiol. Gastrointest. Liver Physiol. | pmid:11960785 |
| Werneburg NW et al. | Tumor necrosis factor-alpha-associated lysosomal permeabilization is cathepsin B dependent. | 2002 | Am. J. Physiol. Gastrointest. Liver Physiol. | pmid:12223355 |
| Anbazhagan AN et al. | Transcriptional modulation of SLC26A3 (DRA) by sphingosine-1-phosphate. | 2016 | Am. J. Physiol. Gastrointest. Liver Physiol. | pmid:27079615 |
| Olsson M et al. | Rat intestinal ceramidase: purification, properties, and physiological relevance. | 2004 | Am. J. Physiol. Gastrointest. Liver Physiol. | pmid:15217782 |
| Fujii R et al. | FTY720 suppresses CD4+CD44highCD62L- effector memory T cell-mediated colitis. | 2006 | Am. J. Physiol. Gastrointest. Liver Physiol. | pmid:16574986 |
| Ikeda H et al. | Biological activities of novel lipid mediator sphingosine 1-phosphate in rat hepatic stellate cells. | 2000 | Am. J. Physiol. Gastrointest. Liver Physiol. | pmid:10915638 |
| Ohama T et al. | Sphingosine-1-phosphate enhances IL-1{beta}-induced COX-2 expression in mouse intestinal subepithelial myofibroblasts. | 2008 | Am. J. Physiol. Gastrointest. Liver Physiol. | pmid:18703638 |
| Dantas AP et al. | Sphingosine 1-phosphate and control of vascular tone. | 2003 | Am. J. Physiol. Heart Circ. Physiol. | pmid:12742827 |
| Kang H et al. | Fluid shear stress modulates endothelial cell invasion into three-dimensional collagen matrices. | 2008 | Am. J. Physiol. Heart Circ. Physiol. | pmid:18805898 |
| Asada S et al. | Downregulation of Dicer expression by serum withdrawal sensitizes human endothelial cells to apoptosis. | 2008 | Am. J. Physiol. Heart Circ. Physiol. | pmid:18978195 |
| Tao R et al. | High-density lipoprotein determines adult mouse cardiomyocyte fate after hypoxia-reoxygenation through lipoprotein-associated sphingosine 1-phosphate. | 2010 | Am. J. Physiol. Heart Circ. Physiol. | pmid:20061542 |
| Gundewar S et al. | Cytoprotective effects of N,N,N-trimethylsphingosine during ischemia- reperfusion injury are lost in the setting of obesity and diabetes. | 2007 | Am. J. Physiol. Heart Circ. Physiol. | pmid:17630348 |
| Zhang G et al. | Sphingosine-1-phosphate prevents permeability increases via activation of endothelial sphingosine-1-phosphate receptor 1 in rat venules. | 2010 | Am. J. Physiol. Heart Circ. Physiol. | pmid:20729401 |
| Soltys CL et al. | Phosphorylation of cardiac protein kinase B is regulated by palmitate. | 2002 | Am. J. Physiol. Heart Circ. Physiol. | pmid:12181135 |
| Lee JF et al. | Balance of S1P1 and S1P2 signaling regulates peripheral microvascular permeability in rat cremaster muscle vasculature. | 2009 | Am. J. Physiol. Heart Circ. Physiol. | pmid:19011048 |
| Wang HH et al. | Nonkinase activity of MLCK in elongated filopodia formation and chemotaxis of vascular smooth muscle cells toward sphingosylphosphorylcholine. | 2009 | Am. J. Physiol. Heart Circ. Physiol. | pmid:19234090 |
| Egom EE et al. | Activation of Pak1/Akt/eNOS signaling following sphingosine-1-phosphate release as part of a mechanism protecting cardiomyocytes against ischemic cell injury. | 2011 | Am. J. Physiol. Heart Circ. Physiol. | pmid:21705677 |
| Liu SJ and Kennedy RH | Positive inotropic effect of ceramide in adult ventricular myocytes: mechanisms dissociated from its reduction in Ca2+ influx. | 2003 | Am. J. Physiol. Heart Circ. Physiol. | pmid:12730052 |
| Adamson RH et al. | Albumin modulates S1P delivery from red blood cells in perfused microvessels: mechanism of the protein effect. | 2014 | Am. J. Physiol. Heart Circ. Physiol. | pmid:24531813 |
| Vessey DA et al. | P2X7 receptor agonists pre- and postcondition the heart against ischemia-reperfusion injury by opening pannexin-1/P2X₇ channels. | 2011 | Am. J. Physiol. Heart Circ. Physiol. | pmid:21685263 |
| Curry FE et al. | Erythrocyte-derived sphingosine-1-phosphate stabilizes basal hydraulic conductivity and solute permeability in rat microvessels. | 2012 | Am. J. Physiol. Heart Circ. Physiol. | pmid:22865384 |
| Hofmann U et al. | Increased myocardial oxygen consumption by TNF-alpha is mediated by a sphingosine signaling pathway. | 2003 | Am. J. Physiol. Heart Circ. Physiol. | pmid:12560208 |
| Hinson JS et al. | Smooth muscle cell-specific transcription is regulated by nuclear localization of the myocardin-related transcription factors. | 2007 | Am. J. Physiol. Heart Circ. Physiol. | pmid:16997888 |
| Bandhuvula P et al. | S1P lyase: a novel therapeutic target for ischemia-reperfusion injury of the heart. | 2011 | Am. J. Physiol. Heart Circ. Physiol. | pmid:21335477 |
| Wang HH et al. | Blebbistatin inhibits the chemotaxis of vascular smooth muscle cells by disrupting the myosin II-actin interaction. | 2008 | Am. J. Physiol. Heart Circ. Physiol. | pmid:18296570 |
| Adamson RH et al. | Attenuation by sphingosine-1-phosphate of rat microvessel acute permeability response to bradykinin is rapidly reversible. | 2012 | Am. J. Physiol. Heart Circ. Physiol. | pmid:22427519 |
| Vessey DA et al. | Sphingosine 1-phosphate is an important endogenous cardioprotectant released by ischemic pre- and postconditioning. | 2009 | Am. J. Physiol. Heart Circ. Physiol. | pmid:19648253 |
| Landeen LK et al. | Sphingosine-1-phosphate receptor expression in cardiac fibroblasts is modulated by in vitro culture conditions. | 2007 | Am. J. Physiol. Heart Circ. Physiol. | pmid:17337593 |
| Means CK et al. | Sphingosine 1-phosphate S1P2 and S1P3 receptor-mediated Akt activation protects against in vivo myocardial ischemia-reperfusion injury. | 2007 | Am. J. Physiol. Heart Circ. Physiol. | pmid:17293497 |
| Li S et al. | Intracellular signal transduction for migration and actin remodeling in vascular smooth muscle cells after sphingosylphosphorylcholine stimulation. | 2006 | Am. J. Physiol. Heart Circ. Physiol. | pmid:16899767 |
| Zhang F et al. | Sphingosine 1-phosphate signaling contributes to cardiac inflammation, dysfunction, and remodeling following myocardial infarction. | 2016 | Am. J. Physiol. Heart Circ. Physiol. | pmid:26589326 |
| Minnear FL et al. | Sphingosine 1-phosphate prevents platelet-activating factor-induced increase in hydraulic conductivity in rat mesenteric venules: pertussis toxin sensitive. | 2005 | Am. J. Physiol. Heart Circ. Physiol. | pmid:15778280 |
| Jin ZQ et al. | Cardioprotection mediated by sphingosine-1-phosphate and ganglioside GM-1 in wild-type and PKC epsilon knockout mouse hearts. | 2002 | Am. J. Physiol. Heart Circ. Physiol. | pmid:12003800 |
| Landeen LK et al. | Mechanisms of the negative inotropic effects of sphingosine-1-phosphate on adult mouse ventricular myocytes. | 2008 | Am. J. Physiol. Heart Circ. Physiol. | pmid:18024550 |
| Patschan S et al. | Lipid mediators of autophagy in stress-induced premature senescence of endothelial cells. | 2008 | Am. J. Physiol. Heart Circ. Physiol. | pmid:18203850 |
| Zeng Y et al. | Sphingosine-1-phosphate protects endothelial glycocalyx by inhibiting syndecan-1 shedding. | 2014 | Am. J. Physiol. Heart Circ. Physiol. | pmid:24285115 |
| Stone ML et al. | Sphingosine-1-phosphate receptor 1 agonism attenuates lung ischemia-reperfusion injury. | 2015 | Am. J. Physiol. Lung Cell Mol. Physiol. | pmid:25910934 |
sphingosine
sphingosine is a lipid of Sphingolipids (SP) class.
Cross Reference
