| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Askew DJ et al. | Characterization of Apt- cell lines exhibiting cross-resistance to glucocorticoid- and Fas-mediated apoptosis. | 1999 | Cell Death Differ. | pmid:10467354 |
| Meacci E et al. | Receptor-mediated activation of phospholipase D by sphingosine 1-phosphate in skeletal muscle C2C12 cells. A role for protein kinase C. | 1999 | FEBS Lett. | pmid:10471775 |
| Mogami K et al. | Sphingosylphosphorylcholine induces cytosolic Ca(2+) elevation in endothelial cells in situ and causes endothelium-dependent relaxation through nitric oxide production in bovine coronary artery. | 1999 | FEBS Lett. | pmid:10471811 |
| Mao C et al. | The dihydrosphingosine-1-phosphate phosphatases of Saccharomyces cerevisiae are important regulators of cell proliferation and heat stress responses. | 1999 | Biochem. J. | pmid:10477278 |
| Saito M et al. | Gangliosides attenuate ethanol-induced apoptosis in rat cerebellar granule neurons. | 1999 | Neurochem. Res. | pmid:10485581 |
| Kahan BD | The potential role of rapamycin in pediatric transplantation as observed from adult studies. | 1999 | Pediatr Transplant | pmid:10487276 |
| Windh RT et al. | Differential coupling of the sphingosine 1-phosphate receptors Edg-1, Edg-3, and H218/Edg-5 to the G(i), G(q), and G(12) families of heterotrimeric G proteins. | 1999 | J. Biol. Chem. | pmid:10488065 |
| Banno Y et al. | Differential phospholipase D activation by bradykinin and sphingosine 1-phosphate in NIH 3T3 fibroblasts overexpressing gelsolin. | 1999 | J. Biol. Chem. | pmid:10488069 |
| Kimura M and Ogihara M | Stimulation by transforming growth factor-alpha of DNA synthesis and proliferation of adult rat hepatocytes in primary cultures: modulation by alpha- and beta-adrenoceptor agonists. | 1999 | J. Pharmacol. Exp. Ther. | pmid:10490901 |
| Kozawa O et al. | Sphingosine 1-phosphate induces heat shock protein 27 via p38 mitogen-activated protein kinase activation in osteoblasts. | 1999 | J. Bone Miner. Res. | pmid:10491224 |
| Hwang MW et al. | FTY720, a new immunosuppressant, promotes long-term graft survival and inhibits the progression of graft coronary artery disease in a murine model of cardiac transplantation. | 1999 | Circulation | pmid:10491378 |
| Goetzl EJ et al. | Dual mechanisms for lysophospholipid induction of proliferation of human breast carcinoma cells. | 1999 | Cancer Res. | pmid:10493533 |
| Young KW et al. | Lysophosphatidic acid-mediated Ca2+ mobilization in human SH-SY5Y neuroblastoma cells is independent of phosphoinositide signalling, but dependent on sphingosine kinase activation. | 1999 | Biochem. J. | pmid:10493910 |
| Hodgson DM et al. | Lysosphingomyelin prevents behavioral aberrations and hippocampal neuron loss induced by the metabotropic glutamate receptor agonist quisqualate. | 1999 | Prog. Neuropsychopharmacol. Biol. Psychiatry | pmid:10509381 |
| Cavallini L et al. | Ganglioside GM1 protection from apoptosis of rat heart fibroblasts. | 1999 | Arch. Biochem. Biophys. | pmid:10510273 |
| Pirianov G et al. | Potentiation by vitamin D analogs of TNFalpha and ceramide-induced apoptosis in MCF-7 cells is associated with activation of cytosolic phospholipase A2. | 1999 | Cell Death Differ. | pmid:10510471 |
| Meroni SB et al. | Effect of N-acetylsphingosine (C2) and the ceramidase inhibitor (1S,2R)-D-erythro-2-(N-myristoylamino)-1-phenyl-1-propanol on the regulation of Sertoli cell function. | 1999 Sep-Oct | J. Androl. | pmid:10520574 |
| Touyz RM and Schiffrin EL | Ang II-stimulated superoxide production is mediated via phospholipase D in human vascular smooth muscle cells. | 1999 | Hypertension | pmid:10523394 |
| Tokura Y et al. | Modulation of T-lymphocyte proliferation by exogenous natural ceramides and sphingosylphosphorylcholine. | 1999 | J. Investig. Dermatol. Symp. Proc. | pmid:10536997 |
| Goetzl EJ et al. | Distinctive expression and functions of the type 4 endothelial differentiation gene-encoded G protein-coupled receptor for lysophosphatidic acid in ovarian cancer. | 1999 | Cancer Res. | pmid:10537322 |
| Yan Z et al. | Cholera toxin induces tumor necrosis factor alpha production in human monocytes. | 1999 | Mol. Cell Biol. Res. Commun. | pmid:10542136 |
| Lee OH et al. | Sphingosine 1-phosphate induces angiogenesis: its angiogenic action and signaling mechanism in human umbilical vein endothelial cells. | 1999 | Biochem. Biophys. Res. Commun. | pmid:10544002 |
| Olivera A et al. | Sphingosine kinase expression increases intracellular sphingosine-1-phosphate and promotes cell growth and survival. | 1999 | J. Cell Biol. | pmid:10545499 |
| Park BJ et al. | Effect of ceramide on apoptosis and phospholipase D activity in FRTL-5 thyroid cells. | 1999 | Exp. Mol. Med. | pmid:10551263 |
| Zenke FT et al. | Identification of a central phosphorylation site in p21-activated kinase regulating autoinhibition and kinase activity. | 1999 | J. Biol. Chem. | pmid:10551809 |
| Xia P et al. | High density lipoproteins (HDL) interrupt the sphingosine kinase signaling pathway. A possible mechanism for protection against atherosclerosis by HDL. | 1999 | J. Biol. Chem. | pmid:10551885 |
| Johns DG et al. | Ceramide-induced vasorelaxation: An inhibitory action on protein kinase C. | 1999 | Gen. Pharmacol. | pmid:10553883 |
| Lee MJ et al. | Vascular endothelial cell adherens junction assembly and morphogenesis induced by sphingosine-1-phosphate. | 1999 | Cell | pmid:10555146 |
| Uehara A et al. | Effect of sphingosylphosphorylcholine on the single channel gating properties of the cardiac ryanodine receptor. | 1999 | FEBS Lett. | pmid:10556518 |
| Hong G et al. | Sphingosine-1-phosphate modulates growth and adhesion of ovarian cancer cells. | 1999 | FEBS Lett. | pmid:10556527 |
| De Jonghe S et al. | Structure-activity relationship of short-chain sphingoid bases as inhibitors of sphingosine kinase. | 1999 | Bioorg. Med. Chem. Lett. | pmid:10560747 |
| Grilley MM and Takemoto JY | Assay of the Saccharomyces cerevisiae dihydrosphingosine C-4 hydroxylase. | 2000 | Meth. Enzymol. | pmid:10563305 |
| Shayman JA and Abe A | Glucosylceramide synthase: assay and properties. | 2000 | Meth. Enzymol. | pmid:10563309 |
| Shayman JA and Abe A | 1-O-acylceramide synthase. | 2000 | Meth. Enzymol. | pmid:10563315 |
| Lee TC | N-acetylation of sphingosine by platelet-activating factor: sphingosine transacetylase. | 2000 | Meth. Enzymol. | pmid:10563316 |
| Lynch DV | Enzymes of sphingolipid metabolism in plants. | 2000 | Meth. Enzymol. | pmid:10563318 |
| Linke T et al. | Purification of acid ceramidase from human placenta. | 2000 | Meth. Enzymol. | pmid:10563326 |
| Olivera A et al. | Assaying sphingosine kinase activity. | 2000 | Meth. Enzymol. | pmid:10563328 |
| Mao C and Obeid LM | Yeast sphingosine-1-phosphate phosphatases: assay, expression, deletion, purification, and cellular localization by GFP tagging. | 2000 | Meth. Enzymol. | pmid:10563329 |
| Brindley DN et al. | Analysis of ceramide 1-phosphate and sphingosine-1-phosphate phosphatase activities. | 2000 | Meth. Enzymol. | pmid:10563330 |
| Van Veldhoven PP | Sphingosine-1-phosphate lyase. | 2000 | Meth. Enzymol. | pmid:10563331 |
| Chung N and Obeid LM | Use of yeast as a model system for studies of sphingolipid metabolism and signaling. | 2000 | Meth. Enzymol. | pmid:10563337 |
| Riley RT and Plattner RD | Fermentation, partial purification, and use of serine palmitoyltransferase inhibitors from Isaria (= Cordyceps) sinclairii. | 2000 | Meth. Enzymol. | pmid:10563339 |
| Curfman C and Liotta D | Synthesis of sphingosine and sphingoid bases. | 2000 | Meth. Enzymol. | pmid:10563342 |
| Jung KH and Schmidt RR | Synthesis of sphingosine, radiolabeled-sphingosine, 4-methyl-cis-sphingosine, and 1-amino derivatives of sphingosine via their azido derivatives. | 2000 | Meth. Enzymol. | pmid:10563343 |
| Koskinen PM and Koskinen AM | Total synthesis of sphingosine and its analogs. | 2000 | Meth. Enzymol. | pmid:10563344 |
| Bielawska A et al. | Radiolabeling of the sphingolipid backbone. | 2000 | Meth. Enzymol. | pmid:10563345 |
| Bielawska A et al. | Synthesis of key precursors of radiolabeled sphingolipids. | 2000 | Meth. Enzymol. | pmid:10563347 |
| Sonnino S et al. | Preparation of radioactive gangliosides, 3H or 14C isotopically labeled at oligosaccharide or ceramide moieties. | 2000 | Meth. Enzymol. | pmid:10563353 |
| McReynolds KD et al. | Synthesis of biotinylated glycoconjugates and their use in a novel ELISA for direct comparison of HIV-1 Gp120 recognition of GalCer and related carbohydrate analogues. | 1999 Nov-Dec | Bioconjug. Chem. | pmid:10563771 |
| FTY 720. | 1999 | Drugs R D | pmid:10565994 | |
| Warden LA et al. | Identification of ammonium ion and 2,6-bis(omega-aminobutyl)- 3, 5-diiminopiperazine as endogenous factors that account for the "burst" of sphingosine upon changing the medium of J774 cells in culture. | 1999 | J. Biol. Chem. | pmid:10567348 |
| Xia P et al. | Activation of sphingosine kinase by tumor necrosis factor-alpha inhibits apoptosis in human endothelial cells. | 1999 | J. Biol. Chem. | pmid:10567432 |
| Meyer zu Heringdorf D et al. | Role of sphingosine kinase in Ca(2+) signalling by epidermal growth factor receptor. | 1999 | FEBS Lett. | pmid:10567700 |
| Ruiz L et al. | Delta9-tetrahydrocannabinol induces apoptosis in human prostate PC-3 cells via a receptor-independent mechanism. | 1999 | FEBS Lett. | pmid:10570948 |
| Castro AF et al. | Mechanism of inhibition of P-glycoprotein-mediated drug transport by protein kinase C blockers. | 1999 | Biochem. Pharmacol. | pmid:10571246 |
| Sekiguchi K et al. | Sphingosylphosphorylcholine induces a hypertrophic growth response through the mitogen-activated protein kinase signaling cascade in rat neonatal cardiac myocytes. | 1999 | Circ. Res. | pmid:10571530 |
| Zhang QH et al. | Redistribution of cytochrome c is not an essential requirement in C2-ceramide induced apoptosis in HL-60 cells. | 1999 | Life Sci. | pmid:10573189 |
| Hozumi Y et al. | Immunotherapy for experimental rat autoimmune thyroiditis using a novel immunosuppressant, FTY720. | 1999 | Life Sci. | pmid:10576553 |
| Suzuki S | FTY720: mechanisms of action and its effect on organ transplantation (review). | 1999 | Transplant. Proc. | pmid:10578288 |
| Omura T et al. | A short-course therapy with FTY720 prolongs allograft survival after canine kidney transplantation. | 1999 | Transplant. Proc. | pmid:10578289 |
| Tamura A et al. | Combination effect of tacrolimus and FTY720 in liver transplantation in rats. | 1999 | Transplant. Proc. | pmid:10578290 |
| Kita Y et al. | Prolonged graft survival induced by CTLA4IG-gene transfection combined with FTY720 administration in rat heart grafting. | 1999 | Transplant. Proc. | pmid:10578291 |
| Fujiwara I et al. | Prolongation of concordant xenograft survival by a newly developed drug, FTY720. | 1999 | Transplant. Proc. | pmid:10578306 |
| Moore AN et al. | Sphingosine-1-phosphate induces apoptosis of cultured hippocampal neurons that requires protein phosphatases and activator protein-1 complexes. | 1999 | Neuroscience | pmid:10579204 |
| Horton JW | Tumor necrosis factor-alpha, sphingosine, ceramide: which is the appropriate marker of inflammation? | 1999 | Crit. Care Med. | pmid:10579290 |
| Moolenaar WH | Bioactive lysophospholipids and their G protein-coupled receptors. | 1999 | Exp. Cell Res. | pmid:10579925 |
| Rodrigues CO et al. | Platelet-activating factor induction of secreted phosphatase activity in Trypanosoma cruzi. | 1999 | Biochem. Biophys. Res. Commun. | pmid:10581161 |
| Yang L et al. | Metabolism and functional effects of sphingolipids in blood cells. | 1999 | Br. J. Haematol. | pmid:10583213 |
| Ramstedt B et al. | Analysis of natural and synthetic sphingomyelins using high-performance thin-layer chromatography. | 1999 | Eur. J. Biochem. | pmid:10583394 |
| Fujikawa K et al. | Role of PI 3-kinase in angiopoietin-1-mediated migration and attachment-dependent survival of endothelial cells. | 1999 | Exp. Cell Res. | pmid:10585289 |
| Wang F et al. | Sphingosine 1-phosphate stimulates cell migration through a G(i)-coupled cell surface receptor. Potential involvement in angiogenesis. | 1999 | J. Biol. Chem. | pmid:10585401 |
| Ito A et al. | Possible involvement of cytochrome c release and sequential activation of caspases in ceramide-induced apoptosis in SK-N-MC cells. | 1999 | Biochim. Biophys. Acta | pmid:10590315 |
| Veldman RJ et al. | Inhibition of P-glycoprotein activity and chemosensitization of multidrug-resistant ovarian carcinoma 2780AD cells by hexanoylglucosylceramide. | 1999 | Biochem. Biophys. Res. Commun. | pmid:10600530 |
| Ogura M and Handa S | Induction of apoptosis by novel synthesized acylamides of human lymphocytes. | 2000 | Biochim. Biophys. Acta | pmid:10601700 |
| Vasta V et al. | Sphingosine 1-phosphate induces arachidonic acid mobilization in A549 human lung adenocarcinoma cells. | 2000 | Biochim. Biophys. Acta | pmid:10601704 |
| McNabb TJ et al. | The separation and direct detection of ceramides and sphingoid bases by normal-phase high-performance liquid chromatography and evaporative light-scattering detection. | 1999 | Anal. Biochem. | pmid:10603247 |
| Lynch KR and Im DS | Life on the edg. | 1999 | Trends Pharmacol. Sci. | pmid:10603487 |
| Chuang FY et al. | Convergence of Fc gamma receptor IIA and Fc gamma receptor IIIB signaling pathways in human neutrophils. | 2000 | J. Immunol. | pmid:10605030 |
| Yang SH and Hong CY | Trilinolein potentiates the pro-aggregating effect of phorbol-12-myristate 13-acetate in human polymorphonuclear leukocytes. | 1999 | Int. J. Immunopharmacol. | pmid:10606003 |
| Susen K et al. | Nerve growth factor stimulates MAPK via the low affinity receptor p75(LNTR). | 1999 | FEBS Lett. | pmid:10606727 |
| Quesniaux V et al. | A novel immunosuppressant, FTY720, induces peripheral lymphodepletion of both T- and B cells and immunosuppression in baboons. | 1999 | Transpl. Immunol. | pmid:10608298 |
| Schürmann A et al. | p21-activated kinase 1 phosphorylates the death agonist bad and protects cells from apoptosis. | 2000 | Mol. Cell. Biol. | pmid:10611223 |
| An S et al. | Sphingosine 1-phosphate-induced cell proliferation, survival, and related signaling events mediated by G protein-coupled receptors Edg3 and Edg5. | 2000 | J. Biol. Chem. | pmid:10617617 |
| Ando M et al. | Non-steroidal anti-inflammatory drugs (NSAIDs) block the late, prostanoid-dependent/ceramide-independent component of ovarian IL-1 action: implications for the ovulatory process. | 1999 | Mol. Cell. Endocrinol. | pmid:10619394 |
| Sabatini M et al. | Effects of ceramide on apoptosis, proteoglycan degradation, and matrix metalloproteinase expression in rabbit articular cartilage. | 2000 | Biochem. Biophys. Res. Commun. | pmid:10623638 |
| Micoli KJ et al. | Requirement of calmodulin binding by HIV-1 gp160 for enhanced FAS-mediated apoptosis. | 2000 | J. Biol. Chem. | pmid:10625668 |
| Wang F et al. | Sphingosine-1-phosphate inhibits motility of human breast cancer cells independently of cell surface receptors. | 1999 | Cancer Res. | pmid:10626811 |
| Xu K and Thornalley PJ | Antitumour activity of sphingoid base adducts of phenethyl isothiocyanate. | 2000 | Bioorg. Med. Chem. Lett. | pmid:10636242 |
| Sato K et al. | Sphingosine 1-phosphate induces expression of early growth response-1 and fibroblast growth factor-2 through mechanism involving extracellular signal-regulated kinase in astroglial cells. | 1999 | Brain Res. Mol. Brain Res. | pmid:10640689 |
| Denisova NA et al. | The role of glutathione, membrane sphingomyelin, and its metabolites in oxidative stress-induced calcium "dysregulation" in PC12 cells. | 1999 | Free Radic. Biol. Med. | pmid:10641723 |
| Allan D | Lipid metabolic changes caused by short-chain ceramides and the connection with apoptosis. | 2000 | Biochem. J. | pmid:10642519 |
| Kurose S et al. | Effects of FTY720, a novel immunosuppressant, on experimental autoimmune uveoretinitis in rats. | 2000 | Exp. Eye Res. | pmid:10644416 |
| Liu J et al. | Hypoxic preconditioning protects cultured neurons against hypoxic stress via TNF-alpha and ceramide. | 2000 | Am. J. Physiol., Cell Physiol. | pmid:10644522 |
| English D et al. | Induction of endothelial cell chemotaxis by sphingosine 1-phosphate and stabilization of endothelial monolayer barrier function by lysophosphatidic acid, potential mediators of hematopoietic angiogenesis. | 1999 | J. Hematother. Stem Cell Res. | pmid:10645770 |
| Lee OH et al. | Sphingosine 1-phosphate stimulates tyrosine phosphorylation of focal adhesion kinase and chemotactic motility of endothelial cells via the G(i) protein-linked phospholipase C pathway. | 2000 | Biochem. Biophys. Res. Commun. | pmid:10652210 |
| Craighead M et al. | Caspases mediate C2-ceramide-induced apoptosis of the human oligodendroglial cell line, MO3.13. | 2000 | Neurosci. Lett. | pmid:10653009 |
| van der Westhuizen L et al. | Sphinganine/sphingosine ratio in plasma and urine as a possible biomarker for fumonisin exposure in humans in rural areas of Africa. | 1999 | Food Chem. Toxicol. | pmid:10654591 |
| Sharma C et al. | Inhibition of Ca2+ release channel (ryanodine receptor) activity by sphingolipid bases: mechanism of action. | 2000 | Chem. Phys. Lipids | pmid:10660207 |
| Tamura A et al. | Immunosuppressive therapy using FTY720 combined with tacrolimus in rat liver transplantation. | 2000 | Surgery | pmid:10660758 |
sphingosine
sphingosine is a lipid of Sphingolipids (SP) class.
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