| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| López-González MA et al. | The production of free oxygen radicals and nitric oxide in the rat cochlea. | 1998 | Neurochem. Int. | pmid:9694043 |
| Lochhead KM and Zager RA | Fluorinated anesthetic exposure "activates" the renal cortical sphingomyelinase cascade. | 1998 | Kidney Int. | pmid:9690203 |
| Ragg SJ et al. | The mitogen-activated protein kinase pathway inhibits ceramide-induced terminal differentiation of a human monoblastic leukemia cell line, U937. | 1998 | J. Immunol. | pmid:9686602 |
| Nakabo Y and Pabst MJ | Inhibition by sphingosine of leukemic cell killing by human monocytes activated with interleukin-2: a possible role of protein kinase C. | 1998 | Jpn. J. Cancer Res. | pmid:9685859 |
| Rossner S et al. | p75 and TrkA receptor signaling independently regulate amyloid precursor protein mRNA expression, isoform composition, and protein secretion in PC12 cells. | 1998 | J. Neurochem. | pmid:9681467 |
| Nagiec MM et al. | The LCB4 (YOR171c) and LCB5 (YLR260w) genes of Saccharomyces encode sphingoid long chain base kinases. | 1998 | J. Biol. Chem. | pmid:9677363 |
| van der Westhuizen L et al. | Inhibition of sphingolipid biosynthesis in rat primary hepatocyte cultures by fumonisin B1 and other structurally related compounds. | 1998 | Food Chem. Toxicol. | pmid:9674957 |
| Johns DG et al. | The role of the endothelium in ceramide-induced vasodilation. | 1998 | Eur. J. Pharmacol. | pmid:9671089 |
| Stam JC et al. | Invasion of T-lymphoma cells: cooperation between Rho family GTPases and lysophospholipid receptor signaling. | 1998 | EMBO J. | pmid:9670021 |
| Saito M et al. | The semisynthetic glycosphingolipid LIGA20 potently protects neurons against apoptosis. | 1998 | Ann. N. Y. Acad. Sci. | pmid:9668359 |
| Riboni L et al. | Metabolic fate of exogenous sphingosine in neuroblastoma neuro2A cells. Dose-dependence and biological effects. | 1998 | Ann. N. Y. Acad. Sci. | pmid:9668342 |
| Igarashi Y | Sphingosine-1-phosphate as an intercellular signaling molecule. | 1998 | Ann. N. Y. Acad. Sci. | pmid:9668340 |
| Spiegel S et al. | Sphingosine-1-phosphate in cell growth and cell death. | 1998 | Ann. N. Y. Acad. Sci. | pmid:9668339 |
| RodrÃguez-Fernández JL and Rozengurt E | Bombesin, vasopressin, lysophosphatidic acid, and sphingosylphosphorylcholine induce focal adhesion kinase activation in intact Swiss 3T3 cells. | 1998 | J. Biol. Chem. | pmid:9668122 |
| Humpf HU et al. | Acylation of naturally occurring and synthetic 1-deoxysphinganines by ceramide synthase. Formation of N-palmitoyl-aminopentol produces a toxic metabolite of hydrolyzed fumonisin, AP1, and a new category of ceramide synthase inhibitor. | 1998 | J. Biol. Chem. | pmid:9668088 |
| Pfau JC et al. | A comparison of the effects of lipopolysaccharide and ceramide on arachidonic acid metabolism in THP-1 monocytic cells. | 1998 | Cell. Immunol. | pmid:9665757 |
| Fukuda Y et al. | Effect of FTY720 on immunoregulation in concordant xenotransplantation. | 1998 | Transpl. Int. | pmid:9665039 |
| Tsunoda M et al. | Early fumonisin B1 toxicity in relation to disrupted sphingolipid metabolism in male BALB/c mice. | 1998 | J. Biochem. Mol. Toxicol. | pmid:9664234 |
| Auzenne E et al. | Cytotoxic effects of sphingolipids as single or multi-modality agents on human melanoma and soft tissue sarcoma in vitro. | 1998 | Melanoma Res. | pmid:9664144 |
| Collins TF et al. | Effects of fumonisin B1 in pregnant rats. | 1998 | Food Chem. Toxicol. | pmid:9662415 |
| Van Brocklyn JR et al. | Dual actions of sphingosine-1-phosphate: extracellular through the Gi-coupled receptor Edg-1 and intracellular to regulate proliferation and survival. | 1998 | J. Cell Biol. | pmid:9660876 |
| Freysz L et al. | Metabolism of brain sphingomyelins: half-lives of sphingosine, fatty acids and phosphate from two types of rat brain sphingomyelin. | 1976 | J. Neurochem. | pmid:965975 |
| Shimeno H et al. | Partial purification and characterization of sphingosine N-acyltransferase (ceramide synthase) from bovine liver mitochondrion-rich fraction. | 1998 | Lipids | pmid:9655376 |
| Oshima M | Identification of glucosyl sphingosine from Gaucher's spleen by gas chromatography-electron impact and GC-chemical ionization mass spectrometry. | 1976 | J. Biochem. | pmid:965366 |
| Noh SJ et al. | Different signaling pathway between sphingosine-1-phosphate and lysophosphatidic acid in Xenopus oocytes: functional coupling of the sphingosine-1-phosphate receptor to PLC-xbeta in Xenopus oocytes. | 1998 | J. Cell. Physiol. | pmid:9648929 |
| Furuya S et al. | Ceramide and its interconvertible metabolite sphingosine function as indispensable lipid factors involved in survival and dendritic differentiation of cerebellar Purkinje cells. | 1998 | J. Neurochem. | pmid:9648886 |
| Hartfield PJ et al. | Neurotrophic factors prevent ceramide-induced apoptosis downstream of c-Jun N-terminal kinase activation in PC12 cells. | 1998 | J. Neurochem. | pmid:9648862 |
| Edmunds NJ and Woodward B | Effects of tumour necrosis factor-alpha on the coronary circulation of the rat isolated perfused heart: a potential role for thromboxane A2 and sphingosine. | 1998 | Br. J. Pharmacol. | pmid:9647473 |
| Gardas A | A structural study on a macro-glycolipid containing 22 sugars isolated from human erythrocytes. | 1976 | Eur. J. Biochem. | pmid:964264 |
| Storchak LG et al. | Differential effect of protein kinase inhibitors on calcium-dependent and calcium-independent [14C]GABA release from rat brain synaptosomes. | 1998 | Neuroscience | pmid:9639290 |
| Hershberger PA et al. | In vitro thymocyte maturation is associated with reduced cellular susceptibility to Fas-mediated apoptosis. | 1998 | Cell. Immunol. | pmid:9636691 |
| Suzuki K et al. | Beneficial immunosuppressive effect of FTY720 combined with intrathymic injection of splenic cells on rat pancreaticoduodenal allograft. | 1998 | Transplant. Proc. | pmid:9636432 |
| Yuzawa K et al. | An effect of FTY720 on acute rejection in canine renal transplantation. | 1998 | Transplant. Proc. | pmid:9636422 |
| Suzuki K et al. | Prevention of experimentally induced autoimmune type I diabetes in rats by the new immunosuppressive reagent FTY720. | 1998 | Transplant. Proc. | pmid:9636421 |
| Antoniou EA et al. | Donor-specific blood transfusion does not enhance the effect of FTY720 in rat cardiac allotransplantation. | 1998 | Transplant. Proc. | pmid:9636420 |
| Zhou H et al. | Inhibition of Akt kinase by cell-permeable ceramide and its implications for ceramide-induced apoptosis. | 1998 | J. Biol. Chem. | pmid:9632728 |
| Boland MP and O'Neill LA | Ceramide activates NFkappaB by inducing the processing of p105. | 1998 | J. Biol. Chem. | pmid:9624136 |
| Nakamura H et al. | Survival by Mac-1-mediated adherence and anoikis in phorbol ester-treated HL-60 cells. | 1998 | J. Biol. Chem. | pmid:9624115 |
| Oyama Y et al. | Cytotoxic actions of FTY720, a novel immunosuppressant, on thymocytes and brain neurons dissociated from the rat. | 1998 | Jpn. J. Pharmacol. | pmid:9623716 |
| Koolpe M et al. | Adenosine 5'-triphosphate, uridine 5'-triphosphate, bradykinin, and lysophosphatidic acid induce different patterns of calcium responses by human articular chondrocytes. | 1998 | J. Orthop. Res. | pmid:9621896 |
| Sakakura C et al. | Selectivity of sphingosine-induced apoptosis. Lack of activity of DL-erythyro-dihydrosphingosine. | 1998 | Biochem. Biophys. Res. Commun. | pmid:9618297 |
| Yanagawa Y et al. | FTY720, a novel immunosuppressant, induces sequestration of circulating mature lymphocytes by acceleration of lymphocyte homing in rats. II. FTY720 prolongs skin allograft survival by decreasing T cell infiltration into grafts but not cytokine production in vivo. | 1998 | J. Immunol. | pmid:9605152 |
| Ichinose Y et al. | Apoptosis induction in synovial fibroblasts by ceramide: in vitro and in vivo effects. | 1998 | J. Lab. Clin. Med. | pmid:9605105 |
| Lanterman MM and Saba JD | Characterization of sphingosine kinase (SK) activity in Saccharomyces cerevisiae and isolation of SK-deficient mutants. | 1998 | Biochem. J. | pmid:9601083 |
| Durrieu F et al. | Caspase activation is an early event in anthracycline-induced apoptosis and allows detection of apoptotic cells before they are ingested by phagocytes. | 1998 | Exp. Cell Res. | pmid:9596989 |
| Canova C et al. | Epigenetic control of programmed cell death: inhibition by 5-azacytidine of 1,25-dihydroxyvitamin D3-induced programmed cell death in C6.9 glioma cells. | 1998 | Mech. Ageing Dev. | pmid:9593321 |
| Marks N et al. | Activation of caspase-3 and apoptosis in cerebellar granule cells. | 1998 | J. Neurosci. Res. | pmid:9590441 |
| Chiba K et al. | FTY720, a novel immunosuppressant, induces sequestration of circulating mature lymphocytes by acceleration of lymphocyte homing in rats. I. FTY720 selectively decreases the number of circulating mature lymphocytes by acceleration of lymphocyte homing. | 1998 | J. Immunol. | pmid:9590253 |
| Tas PW and Koschel K | Sphingosine-1-phosphate induces a Ca2+ signal in primary rat astrocytes and a Ca2+ signal and shape changes in C6 rat glioma cells. | 1998 | J. Neurosci. Res. | pmid:9589387 |
| Himmel HM et al. | Guanine nucleotide-sensitive inhibition of L-type Ca2+ current by lysosphingolipids in RINm5F insulinoma cells. | 1998 | Mol. Pharmacol. | pmid:9584212 |
| Meyer zu Heringdorf D et al. | Sphingosine kinase-mediated Ca2+ signalling by G-protein-coupled receptors. | 1998 | EMBO J. | pmid:9582276 |
| Kleuser B et al. | 1Alpha,25-dihydroxyvitamin D3 inhibits programmed cell death in HL-60 cells by activation of sphingosine kinase. | 1998 | Cancer Res. | pmid:9581819 |
| Kuo ML et al. | Transforming growth factor beta1 attenuates ceramide-induced CPP32/Yama activation and apoptosis in human leukaemic HL-60 cells. | 1997 | Biochem. J. | pmid:9581540 |
| Wang ME et al. | Immunosuppressive effects of FTY720 alone or in combination with cyclosporine and/or sirolimus. | 1998 | Transplantation | pmid:9565092 |
| Kirtikara K et al. | An accessory role for ceramide in interleukin-1beta induced prostaglandin synthesis. | 1998 | Mol. Cell. Biochem. | pmid:9562240 |
| Suzuki S et al. | An immunosuppressive regimen using FTY720 combined with cyclosporin in canine kidney transplantation. | 1998 | Transpl. Int. | pmid:9561675 |
| Kishida E et al. | Distinctive inhibitory activity of docosahexaenoic acid against sphingosine-induced apoptosis. | 1998 | Biochim. Biophys. Acta | pmid:9555103 |
| Harada-Shiba M et al. | Oxidized low density lipoprotein induces apoptosis in cultured human umbilical vein endothelial cells by common and unique mechanisms. | 1998 | J. Biol. Chem. | pmid:9545302 |
| Melendez A et al. | FcgammaRI coupling to phospholipase D initiates sphingosine kinase-mediated calcium mobilization and vesicular trafficking. | 1998 | J. Biol. Chem. | pmid:9545263 |
| Kimura M and Ogihara M | Proliferation of adult rat hepatocytes in primary cultures induced by platelet-derived growth factor is potentiated by phenylephrine. | 1998 | Jpn. J. Pharmacol. | pmid:9541279 |
| Sweeney EA et al. | Inhibition of sphingolipid induced apoptosis by caspase inhibitors indicates that sphingosine acts in an earlier part of the apoptotic pathway than ceramide. | 1998 | FEBS Lett. | pmid:9541007 |
| Iwasaki-Bessho Y et al. | Decreased phospholipase D (PLD) activity in ceramide-induced apoptosis of human keratinocyte cell line HaCaT. | 1998 | J. Invest. Dermatol. | pmid:9540978 |
| Hisano N et al. | Quantification of sphingosine derivatives in human platelets: inducible formation of free sphingosine. | 1998 | J. Biochem. | pmid:9538201 |
| Kao MC et al. | In vitro gene transfer in mammalian cells via a new cationic liposome formulation. | 1998 May-Jun | Oncol. Rep. | pmid:9538164 |
| Searl TJ and Silinsky EM | Increases in acetylcholine release produced by phorbol esters are not mediated by protein kinase C at motor nerve endings. | 1998 | J. Pharmacol. Exp. Ther. | pmid:9536018 |
| Hamada K et al. | Involvement of Mac-1-mediated adherence and sphingosine 1-phosphate in survival of phorbol ester-treated U937 cells. | 1998 | Biochem. Biophys. Res. Commun. | pmid:9535736 |
| Veldman RJ et al. | Metabolism and apoptotic properties of elevated ceramide in HT29rev cells. | 1998 | Biochem. J. | pmid:9531498 |
| Flores I et al. | Dual role of ceramide in the control of apoptosis following IL-2 withdrawal. | 1998 | J. Immunol. | pmid:9531315 |
| Foghi A et al. | Fas-induced apoptosis in rat thecal/interstitial cells signals through sphingomyelin-ceramide pathway. | 1998 | Endocrinology | pmid:9528992 |
| Bokoch GM et al. | A GTPase-independent mechanism of p21-activated kinase activation. Regulation by sphingosine and other biologically active lipids. | 1998 | J. Biol. Chem. | pmid:9525917 |
| Crilly KS et al. | The choline kinase inhibitor hemicholinium-3 can inhibit mitogen-induced DNA synthesis independent of its effect on phosphocholine formation. | 1998 | Arch. Biochem. Biophys. | pmid:9521826 |
| Galvan V and Roizman B | Herpes simplex virus 1 induces and blocks apoptosis at multiple steps during infection and protects cells from exogenous inducers in a cell-type-dependent manner. | 1998 | Proc. Natl. Acad. Sci. U.S.A. | pmid:9520470 |
| Czajkowski R et al. | Sphingosine modulates Ca2+ signals via phospholipase C dependent pathway in glioma C6 cells. | 1997 | Acta Neurobiol Exp (Wars) | pmid:9519554 |
| Berger A et al. | The potent lipid mitogen sphingosylphosphocholine activates the DNA binding activity of upstream stimulating factor (USF), a basic helix-loop-helix-zipper protein. | 1998 | Biochim. Biophys. Acta | pmid:9507145 |
| Wakita H et al. | Sphingosylphosphorylcholine stimulates proliferation and upregulates cell surface-associated plasminogen activator activity in cultured human keratinocytes. | 1998 | J. Invest. Dermatol. | pmid:9506444 |
| Igarashi Y | Functional roles of sphingosine, sphingosine 1-phosphate, and methylsphingosines: in regard to membrane sphingolipid signaling pathways. | 1997 | J. Biochem. | pmid:9498549 |
| Muramatsu K et al. | A new immunosuppressant, FTY720, prolongs limb allograft survival in rats. | 1998 | Ann Plast Surg | pmid:9495465 |
| Monney L et al. | Role of an acidic compartment in tumor-necrosis-factor-alpha-induced production of ceramide, activation of caspase-3 and apoptosis. | 1998 | Eur. J. Biochem. | pmid:9492297 |
| Lee SC et al. | The naturally occurring PKC inhibitor sphingosine and tumor promoter phorbol ester potentially induce tyrosine phosphorylation/activation of oncogenic proline-directed protein kinase FA/GSK-3alpha in a common signalling pathway. | 1998 | J. Protein Chem. | pmid:9491924 |
| Takeda H et al. | Sphingomyelinase and ceramide inhibit formation of F-actin ring in and bone resorption by rabbit mature osteoclasts. | 1998 | FEBS Lett. | pmid:9490019 |
| Lee MJ et al. | Sphingosine-1-phosphate as a ligand for the G protein-coupled receptor EDG-1. | 1998 | Science | pmid:9488656 |
| Simon CG and Gear AR | Membrane-destabilizing properties of C2-ceramide may be responsible for its ability to inhibit platelet aggregation. | 1998 | Biochemistry | pmid:9485333 |
| Sakai T et al. | Effects of alpha- and beta-galactosylated C2-ceramides on the immune system. | 1998 | J. Med. Chem. | pmid:9484513 |
| Kim BC and Kim JH | Exogenous C2-ceramide activates c-fos serum response element via Rac-dependent signalling pathway. | 1998 | Biochem. J. | pmid:9480923 |
| Zondag GC et al. | Sphingosine 1-phosphate signalling through the G-protein-coupled receptor Edg-1. | 1998 | Biochem. J. | pmid:9480864 |
| Reunanen N et al. | Enhancement of fibroblast collagenase (matrix metalloproteinase-1) gene expression by ceramide is mediated by extracellular signal-regulated and stress-activated protein kinase pathways. | 1998 | J. Biol. Chem. | pmid:9478967 |
| Lawler JF et al. | Tumor necrosis factor-alpha stimulates the maturation of sterol regulatory element binding protein-1 in human hepatocytes through the action of neutral sphingomyelinase. | 1998 | J. Biol. Chem. | pmid:9478955 |
| Schmelz EM et al. | Induction of apoptosis by fumonisin B1 in HT29 cells is mediated by the accumulation of endogenous free sphingoid bases. | 1998 | Toxicol. Appl. Pharmacol. | pmid:9473533 |
| Maguer-Satta V et al. | BCR-ABL accelerates C2-ceramide-induced apoptosis. | 1998 | Oncogene | pmid:9464542 |
| Zhou J and Saba JD | Identification of the first mammalian sphingosine phosphate lyase gene and its functional expression in yeast. | 1998 | Biochem. Biophys. Res. Commun. | pmid:9464245 |
| Chigorno V et al. | Metabolic processing of gangliosides by human fibroblasts in culture--formation and recycling of separate pools of sphingosine. | 1997 | Eur. J. Biochem. | pmid:9461288 |
| Kawa S et al. | Inhibition of chemotactic motility and trans-endothelial migration of human neutrophils by sphingosine 1-phosphate. | 1997 | FEBS Lett. | pmid:9459309 |
| Kaneshiro ES et al. | Identification and initial characterizations of free, glycosylated, and phosphorylated ceramides of Paramecium. | 1997 | J. Lipid Res. | pmid:9458264 |
| Zehavi U | Synthesis of potentially caged sphingolipids, possible precursors of cellular modulators and second messengers. | 1997 | Chem. Phys. Lipids | pmid:9450322 |
| Keenan C et al. | Assay to determine the isoform specificity of protein kinase C inhibitors. | 1997 | Biochem. Soc. Trans. | pmid:9450019 |
| Conway AM et al. | Sphingosine 1-phosphate activation of MAP kinase--involvement of PI 3-kinase and protein kinase C. | 1997 | Biochem. Soc. Trans. | pmid:9450013 |
| Cuvillier O et al. | Sphingosine 1-phosphate inhibits activation of caspases that cleave poly(ADP-ribose) polymerase and lamins during Fas- and ceramide-mediated apoptosis in Jurkat T lymphocytes. | 1998 | J. Biol. Chem. | pmid:9446602 |
| Skrzypek MS et al. | Inhibition of amino acid transport by sphingoid long chain bases in Saccharomyces cerevisiae. | 1998 | J. Biol. Chem. | pmid:9446592 |
| Hashizume T et al. | Sphingosine enhances arachidonic acid liberation in response to U46619 through an increase in phospholipase A2 activity in rabbit platelets. | 1997 | J. Biochem. | pmid:9443821 |
| Tanabe F et al. | Ceramide promotes calpain-mediated proteolysis of protein kinase C beta in murine polymorphonuclear leukocytes. | 1998 | Biochem. Biophys. Res. Commun. | pmid:9439623 |
sphingosine
sphingosine is a lipid of Sphingolipids (SP) class.
Cross Reference
