| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Gharbaran R | Insights into the molecular roles of heparan sulfate proteoglycans (HSPGs-syndecans) in autocrine and paracrine growth factor signaling in the pathogenesis of Hodgkin's lymphoma. | 2016 | Tumour Biol. | pmid:27317256 |
| Zhang L et al. | FTY720 reduces migration and invasion of human glioblastoma cell lines via inhibiting the PI3K/AKT/mTOR/p70S6K signaling pathway. | 2014 | Tumour Biol. | pmid:25070489 |
| Müller R et al. | Expression of sphingosine-1-phosphate receptors and lysophosphatidic acid receptors on cultured and xenografted human colon, breast, melanoma, and lung tumor cells. | 2010 | Tumour Biol. | pmid:20480410 |
| Li J et al. | Overexpression of SphK1 enhances cell proliferation and invasion in triple-negative breast cancer via the PI3K/AKT signaling pathway. | 2016 | Tumour Biol. | pmid:26857281 |
| Zhang Z et al. | SPHK1 inhibitor suppresses cell proliferation and invasion associated with the inhibition of NF-κB pathway in hepatocellular carcinoma. | 2015 | Tumour Biol. | pmid:25537088 |
| Nakajima M et al. | The role of sphingosine-1-phosphate in the tumor microenvironment and its clinical implications. | 2017 | Tumour Biol. | pmid:28381169 |
| Hu L et al. | TF/FVIIa/PAR2 promotes cell proliferation and migration via PKCα and ERK-dependent c-Jun/AP-1 pathway in colon cancer cell line SW620. | 2013 | Tumour Biol. | pmid:23616010 |
| Worrall D et al. | Sphingolipids, new players in plant signaling. | 2003 | Trends Plant Sci. | pmid:12878015 |
| Lynch DV et al. | Lipid signaling in Arabidopsis: no sphingosine? No problem! | 2009 | Trends Plant Sci. | pmid:19716747 |
| Napier JA et al. | A new class of lipid desaturase central to sphingolipid biosynthesis and signalling. | 2002 | Trends Plant Sci. | pmid:12417141 |
| Lynch KR and Im DS | Life on the edg. | 1999 | Trends Pharmacol. Sci. | pmid:10603487 |
| Im DS | Linking Chinese medicine and G-protein-coupled receptors. | 2003 | Trends Pharmacol. Sci. | pmid:12498721 |
| Maguire JJ and Davenport AP | Regulation of vascular reactivity by established and emerging GPCRs. | 2005 | Trends Pharmacol. Sci. | pmid:16054240 |
| Salvemini D et al. | Therapeutic targeting of the ceramide-to-sphingosine 1-phosphate pathway in pain. | 2013 | Trends Pharmacol. Sci. | pmid:23318139 |
| Chi H | Sphingosine-1-phosphate and immune regulation: trafficking and beyond. | 2011 | Trends Pharmacol. Sci. | pmid:21159389 |
| Brinkmann V et al. | FTY720: a novel transplantation drug that modulates lymphocyte traffic rather than activation. | 2000 | Trends Pharmacol. Sci. | pmid:10664606 |
| O'Sullivan C and Dev KK | The structure and function of the S1P1 receptor. | 2013 | Trends Pharmacol. Sci. | pmid:23763867 |
| Gardell SE et al. | Emerging medicinal roles for lysophospholipid signaling. | 2006 | Trends Mol Med | pmid:16406843 |
| Pyne S and Pyne NJ | Translational aspects of sphingosine 1-phosphate biology. | 2011 | Trends Mol Med | pmid:21514226 |
| Nielsen OH et al. | Sphingosine-1-Phosphate Signaling in Inflammatory Bowel Disease. | 2017 | Trends Mol Med | pmid:28283249 |
| Prager B et al. | Sphingosine 1-phosphate signaling at the blood-brain barrier. | 2015 | Trends Mol Med | pmid:25939882 |
| Walzer T and Vivier E | G-protein-coupled receptors in control of natural killer cell migration. | 2011 | Trends Immunol. | pmid:21664184 |
| Rosen H et al. | Tipping the gatekeeper: S1P regulation of endothelial barrier function. | 2007 | Trends Immunol. | pmid:17276731 |
| Sasset L et al. | Sphingolipid De Novo Biosynthesis: A Rheostat of Cardiovascular Homeostasis. | 2016 | Trends Endocrinol. Metab. | pmid:27562337 |
| Garbers DL et al. | Membrane guanylyl cyclase receptors: an update. | 2006 | Trends Endocrinol. Metab. | pmid:16815030 |
| Alvarez SE et al. | Autocrine and paracrine roles of sphingosine-1-phosphate. | 2007 | Trends Endocrinol. Metab. | pmid:17904858 |
| Spiegel S et al. | Sphingosine 1-phosphate signaling: providing cells with a sense of direction. | 2002 | Trends Cell Biol. | pmid:12062172 |
| Maceyka M et al. | Sphingosine-1-phosphate signaling and its role in disease. | 2012 | Trends Cell Biol. | pmid:22001186 |
| Morris AJ et al. | Blood relatives: dynamic regulation of bioactive lysophosphatidic acid and sphingosine-1-phosphate metabolism in the circulation. | 2009 | Trends Cardiovasc. Med. | pmid:19818950 |
| Marletta MA | Another activation switch for endothelial nitric oxide synthase: why does it have to be so complicated? | 2001 | Trends Biochem. Sci. | pmid:11551775 |
| Adams DR et al. | Sphingosine Kinases: Emerging Structure-Function Insights. | 2016 | Trends Biochem. Sci. | pmid:27021309 |
| Böhler T et al. | FTY720 mediates apoptosis-independent lymphopenia in human renal allograft recipients: different effects on CD62L+ and CCR5+ T lymphocytes. | 2004 | Transplantation | pmid:15167602 |
| Calne SR | FTY: not just a homely drug. | 2004 | Transplantation | pmid:15167585 |
| Wijkstrom M et al. | Islet allograft survival in nonhuman primates immunosuppressed with basiliximab, RAD, and FTY720. | 2004 | Transplantation | pmid:15077021 |
| Yin N et al. | Targeting lymphangiogenesis after islet transplantation prolongs islet allograft survival. | 2011 | Transplantation | pmid:21508896 |
| Chueh SC et al. | Induction of tolerance toward rat cardiac allografts by treatment with allochimeric class I MHC antigen and FTY720. | 1997 | Transplantation | pmid:9392303 |
| Zhang EP et al. | Significant prolongation of orthotopic corneal-graft survival in FTY720-treated mice. | 2003 | Transplantation | pmid:14657695 |
| Kim JY et al. | Effect of FTY720 on chronic cyclosporine nephropathy in rats. | 2005 | Transplantation | pmid:16314802 |
| Lee RS et al. | FTY720 does not abrogate acute graft-versus-host disease in the dog leukocyte antigen-nonidentical unrelated canine model. | 2003 | Transplantation | pmid:14578745 |
| Delbridge MS et al. | Reduction of ischemia-reperfusion injury in the rat kidney by FTY720, a synthetic derivative of sphingosine. | 2007 | Transplantation | pmid:17667810 |
| Tchorsh-Yutsis D et al. | Embryonic pig pancreatic tissue for the treatment of diabetes: potential role of immune suppression with "off-the-shelf" third-party regulatory T cells. | 2011 | Transplantation | pmid:21192322 |
| Oppenheimer F et al. | Impact of long-term therapy with FTY720 or mycophenolate mofetil on cardiac conduction and rhythm in stable adult renal transplant patients. | 2007 | Transplantation | pmid:17353787 |
| Matsumoto Y et al. | Efficacy of mycophenolate sodium as monotherapy and in combination with FTY720 in a DA-to-Lewis-rat heart-transplantation model. | 2002 | Transplantation | pmid:12451233 |
| Kahan BD et al. | Pharmacodynamics, pharmacokinetics, and safety of multiple doses of FTY720 in stable renal transplant patients: a multicenter, randomized, placebo-controlled, phase I study. | 2003 | Transplantation | pmid:14557756 |
| Fu F et al. | Long-term islet graft survival in streptozotocin- and autoimmune-induced diabetes models by immunosuppressive and potential insulinotropic agent FTY720. | 2002 | Transplantation | pmid:12023620 |
| Troncoso P et al. | Prophylaxis of acute renal allograft rejection using FTY720 in combination with subtherapeutic doses of cyclosporine. | 1999 | Transplantation | pmid:9921811 |
| Xun CQ et al. | What role for FTY720, a novel immunosuppressive agent, in canine nonmyeloablative hematopoietic stem cell transplantation? | 2002 | Transplantation | pmid:11821753 |
| Schuurman HJ et al. | Oral efficacy of the new immunomodulator FTY720 in cynomolgus monkey kidney allotransplantation, given alone or in combination with cyclosporine or RAD. | 2002 | Transplantation | pmid:12394836 |
| Maki T et al. | Prevention and cure of autoimmune diabetes in nonobese diabetic mice by continuous administration of FTY720. | 2005 | Transplantation | pmid:15880042 |
| Böhler T et al. | Novel mediators of FTY720 in human lymphocytes. | 2005 | Transplantation | pmid:15729178 |
sphingosine
sphingosine is a lipid of Sphingolipids (SP) class.
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