sphingosine

sphingosine is a lipid of Sphingolipids (SP) class.

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There are no associated biomedical information in the current reference collection.

Current reference collection contains 26061 references associated with sphingosine in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

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Authors Title Published Journal PubMed Link
Meissner A et al. Sphingosine-1-phosphate signalling-a key player in the pathogenesis of Angiotensin II-induced hypertension. 2017 Cardiovasc. Res. pmid:28082452
Atkinson D et al. Sphingosine 1-phosphate lyase deficiency causes Charcot-Marie-Tooth neuropathy. 2017 Neurology pmid:28077491
Ng ML et al. The role of sphingolipid signalling in diabetes‑associated pathologies (Review). 2017 Int. J. Mol. Med. pmid:28075451
van der Weyden L et al. Genome-wide in vivo screen identifies novel host regulators of metastatic colonization. 2017 Nature pmid:28052056
Lima S et al. Sphingosine and Sphingosine Kinase 1 Involvement in Endocytic Membrane Trafficking. 2017 J. Biol. Chem. pmid:28049734
Ruiz M et al. High-Density Lipoprotein-Associated Apolipoprotein M Limits Endothelial Inflammation by Delivering Sphingosine-1-Phosphate to the Sphingosine-1-Phosphate Receptor 1. 2017 Arterioscler. Thromb. Vasc. Biol. pmid:27879252
Barnawi J et al. Reduced DNA methylation of sphingosine-1 phosphate receptor 5 in alveolar macrophages in COPD: A potential link to failed efferocytosis. 2017 Respirology pmid:27868302
Frias MA et al. High-density lipoprotein-associated sphingosine-1-phosphate activity in heterozygous familial hypercholesterolaemia. 2017 Eur. J. Clin. Invest. pmid:27861771
Fang V et al. Gradients of the signaling lipid S1P in lymph nodes position natural killer cells and regulate their interferon-γ response. 2017 Nat. Immunol. pmid:27841869
Wang R et al. Hepatic Stellate Cell Selective Disruption of Dynamin-2 GTPase Increases Murine Fibrogenesis through Up-Regulation of Sphingosine-1 Phosphate-Induced Cell Migration. 2017 Am. J. Pathol. pmid:27840081
Pal SK et al. A phase 2 study of the sphingosine-1-phosphate antibody sonepcizumab in patients with metastatic renal cell carcinoma. 2017 Cancer pmid:27727447
Yang J et al. C2-ceramide influences alveolar epithelial barrier function by downregulating Zo-1, occludin and claudin-4 expression. 2017 Toxicol. Mech. Methods pmid:28052715
Mendelson K et al. The ceramide synthase 2b gene mediates genomic sensing and regulation of sphingosine levels during zebrafish embryogenesis. 2017 Elife pmid:28956531
Pierucci F et al. Non-dioxin-like organic toxicant PCB153 modulates sphingolipid metabolism in liver progenitor cells: its role in Cx43-formed gap junction impairment. 2017 Arch. Toxicol. pmid:27318803
Pierucci F et al. Vitamin D protects against Aβ peptide cytotoxicity in differentiated human neuroblastoma SH- SY5Y cells: A role for S1P1/p38MAPK/ATF4 axis. 2017 Neuropharmacology pmid:28077289
Leo A et al. The Sphingosine 1-Phosphate Signaling Pathway in Epilepsy: A Possible Role for the Immunomodulator Drug Fingolimod in Epilepsy Treatment. 2017 CNS Neurol Disord Drug Targets pmid:27823573
Xiao W et al. Fingolimod Suppresses a Cascade of Core Vicious Cycle in Dry Eye NOD Mouse Model: Involvement of Sphingosine-1-Phosphate Receptors in Infiltrating Leukocytes. 2017 Invest. Ophthalmol. Vis. Sci. pmid:29214311
Roch L et al. High-Resolution Expression Profiling of Peripheral Blood CD8 Cells in Patients with Multiple Sclerosis Displays Fingolimod-Induced Immune Cell Redistribution. 2017 Mol. Neurobiol. pmid:27631876
Onuma T et al. Sphingosine 1-phosphate (S1P) suppresses the collagen-induced activation of human platelets via S1P4 receptor. 2017 Thromb. Res. pmid:28609704
Meissner A S1PR (Sphingosine-1-Phosphate Receptor) Signaling in the Regulation of Vascular Tone and Blood Pressure: Is S1PR1 Doing the Trick? 2017 Hypertension pmid:28607129
Di Pietro M et al. In vivo intrabursal administration of bioactive lipid sphingosine-1-phosphate enhances vascular integrity in a rat model of ovarian hyperstimulation syndrome. 2017 Mol. Hum. Reprod. pmid:28379469
Pulkoski-Gross MJ et al. Novel sphingosine kinase-1 inhibitor, LCL351, reduces immune responses in murine DSS-induced colitis. 2017 Prostaglandins Other Lipid Mediat. pmid:28377281
Seo Y et al. Sphingosine-1-phosphate is involved in inflammatory reactions in patients with Graves' orbitopathy. 2017 Inflamm. Res. pmid:28364200
Schumacher F et al. The sphingosine 1-phosphate breakdown product, (2)-hexadecenal, forms protein adducts and glutathione conjugates in vitro. 2017 J. Lipid Res. pmid:28588048
Garnero P The Utility of Biomarkers in Osteoporosis Management. 2017 Mol Diagn Ther pmid:28271451
Schonauer S et al. Identification of a feedback loop involving β-glucosidase 2 and its product sphingosine sheds light on the molecular mechanisms in Gaucher disease. 2017 J. Biol. Chem. pmid:28258214
Kitchen SA and Weis VM The sphingosine rheostat is involved in the cnidarian heat stress response but not necessarily in bleaching. 2017 J. Exp. Biol. pmid:28250108
Ebenezer DL et al. Epigenetic regulation of pro-inflammatory cytokine secretion by sphingosine 1-phosphate (S1P) in acute lung injury: Role of S1P lyase. 2017 Adv Biol Regul pmid:27720306
Barbour M et al. Effect of sphingosine kinase modulators on interleukin-1β release, sphingosine 1-phosphate receptor 1 expression and experimental autoimmune encephalomyelitis. 2017 Br. J. Pharmacol. pmid:27864936
Feuerborn R et al. High density lipoprotein (HDL)-associated sphingosine 1-phosphate (S1P) inhibits macrophage apoptosis by stimulating STAT3 activity and survivin expression. 2017 Atherosclerosis pmid:28038379
Thieme M et al. Sphingosine-1-phosphate modulators in inflammatory skin diseases - lining up for clinical translation. 2017 Exp. Dermatol. pmid:27574180
Chang N et al. HuR mediates motility of human bone marrow-derived mesenchymal stem cells triggered by sphingosine 1-phosphate in liver fibrosis. 2017 J. Mol. Med. pmid:27543493
Kuchar L et al. Quantitation of plasmatic lysosphingomyelin and lysosphingomyelin-509 for differential screening of Niemann-Pick A/B and C diseases. 2017 Anal. Biochem. pmid:28259515
Wang M et al. Automated tracking and quantification of angiogenic vessel formation in 3D microfluidic devices. 2017 PLoS ONE pmid:29136008
Tran HB et al. Disrupted epithelial/macrophage crosstalk via Spinster homologue 2-mediated S1P signaling may drive defective macrophage phagocytic function in COPD. 2017 PLoS ONE pmid:29112690
Luo J et al. The effects of berberine on a murine model of multiple sclerosis and the SPHK1/S1P signaling pathway. 2017 Biochem. Biophys. Res. Commun. pmid:28655617
Chang CH and Randolph GJ Sphingosine-1-Phosphate as the Lymphocyte's Ticket to Ride and Survive. 2017 Dev. Cell pmid:28633013
Fang R et al. Sphingosine 1-Phosphate Postconditioning Protects Against Myocardial Ischemia/reperfusion Injury in Rats via Mitochondrial Signaling and Akt-Gsk3β Phosphorylation. 2017 Arch. Med. Res. pmid:28625317
Rohrbach T et al. Sphingosine kinase and sphingosine-1-phosphate in liver pathobiology. 2017 Crit. Rev. Biochem. Mol. Biol. pmid:28618839
Vijayan M et al. Sphingosine 1-Phosphate Lyase Enhances the Activation of IKKε To Promote Type I IFN-Mediated Innate Immune Responses to Influenza A Virus Infection. 2017 J. Immunol. pmid:28600291
Nakajima M et al. The role of sphingosine-1-phosphate in the tumor microenvironment and its clinical implications. 2017 Tumour Biol. pmid:28381169
Garbowska M et al. Sphingolipids metabolism in the salivary glands of rats with obesity and streptozotocin induced diabetes. 2017 J. Cell. Physiol. pmid:28369933
Turner VM and Mabbott NA Ageing adversely affects the migration and function of marginal zone B cells. 2017 Immunology pmid:28369800
Müller J et al. Differential S1P Receptor Profiles on M1- and M2-Polarized Macrophages Affect Macrophage Cytokine Production and Migration. 2017 Biomed Res Int pmid:28367448
Su K et al. FTY720 Attenuates Angiotensin II-Induced Podocyte Damage via Inhibiting Inflammatory Cytokines. 2017 Mediators Inflamm. pmid:28270699
Serafimidis I et al. Pancreas lineage allocation and specification are regulated by sphingosine-1-phosphate signalling. 2017 PLoS Biol. pmid:28248965
Lee HM et al. Oncogenic S1P signalling in EBV-associated nasopharyngeal carcinoma activates AKT and promotes cell migration through S1P receptor 3. 2017 J. Pathol. pmid:28240350
Alvares DS et al. Phosphatidylserine lipids and membrane order precisely regulate the activity of Polybia-MP1 peptide. 2017 Biochim. Biophys. Acta pmid:28274844
Jadhav S et al. Inositol Depletion Induced by Acute Treatment of the Bipolar Disorder Drug Valproate Increases Levels of Phytosphingosine. 2017 J. Biol. Chem. pmid:28100786
Fujii A et al. Selective Absorption of Dietary Sphingoid Bases from the Intestine via Efflux by P-Glycoprotein in Rats. 2017 J. Nutr. Sci. Vitaminol. pmid:28367925