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Stem Cells |
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Selective coupling of the S1P receptor subtype to S1P-mediated RhoA activation and cardioprotection. |
2017 |
J. Mol. Cell. Cardiol. |
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Unsupervised analysis of combined lipid and coagulation data reveals coagulopathy subtypes among dialysis patients. |
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J. Lipid Res. |
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Vascular and Immunobiology of the Circulatory Sphingosine 1-Phosphate Gradient. |
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Annu. Rev. Physiol. |
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Doxorubicin effect is enhanced by sphingosine-1-phosphate signaling antagonist in breast cancer. |
2017 |
J. Surg. Res. |
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Therapeutic Strategies and Pharmacological Tools Influencing S1P Signaling and Metabolism. |
2017 |
Med Res Rev |
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Jiang S et al. |
C2-ceramide enhances sorafenib-induced caspase-dependent apoptosis via PI3K/AKT/mTOR and Erk signaling pathways in HCC cells. |
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S1P Provokes Tumor Lymphangiogenesis via Macrophage-Derived Mediators Such as IL-1 or Lipocalin-2. |
2017 |
Mediators Inflamm. |
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Acid ceramidase confers radioresistance to glioblastoma cells. |
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Oncol. Rep. |
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Implication of sphingosine-1-phosphate signaling in diseases: molecular mechanism and therapeutic strategies. |
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Urine Metabonomics Reveals Early Biomarkers in Diabetic Cognitive Dysfunction. |
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Plasma sphingosine-1-phosphate concentrations are associated with systolic heart failure in patients with ischemic heart disease. |
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Pleiotropic effects of sphingosine-1-phosphate signaling to control human chorionic mesenchymal stem cell physiology. |
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Cell Death Dis |
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Involvement of sphingosine kinase/sphingosine 1-phosphate metabolic pathway in spondyloarthritis. |
2017 |
Bone |
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Sphingosine-1-phosphate suppresses chondrosarcoma metastasis by upregulation of tissue inhibitor of metalloproteinase 3 through suppressing miR-101 expression. |
2017 |
Mol Oncol |
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Sphingosine rescues aged mice from pulmonary pseudomonas infection. |
2017 |
J. Surg. Res. |
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Mfsd2b is essential for the sphingosine-1-phosphate export in erythrocytes and platelets. |
2017 |
Nature |
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Neutrophils Kill Reactive Oxygen Species-Resistant Pseudomonas aeruginosa by Sphingosine. |
2017 |
Cell. Physiol. Biochem. |
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The balance between Gα-Cdc42/Rac and Gα/-RhoA pathways determines endothelial barrier regulation by sphingosine-1-phosphate. |
2017 |
Mol. Biol. Cell |
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Jaspine B induces nonapoptotic cell death in gastric cancer cells independently of its inhibition of ceramide synthase. |
2017 |
J. Lipid Res. |
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β1-Integrin Accumulates in Cystic Fibrosis Luminal Airway Epithelial Membranes and Decreases Sphingosine, Promoting Bacterial Infections. |
2017 |
Cell Host Microbe |
pmid:28552668
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Azimzadeh K et al. |
Evaluation of plasma sphingosine 1-phosphate, hepcidin and cardiovascular damage biomarkers (cardiac troponin I and homocysteine) in rats infected with brucellosis and vaccinated (Rev-1, RB-51). |
2017 |
Microb. Pathog. |
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Alqinyah M et al. |
Regulator of G Protein Signaling 10 (Rgs10) Expression Is Transcriptionally Silenced in Activated Microglia by Histone Deacetylase Activity. |
2017 |
Mol. Pharmacol. |
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Sphingosine metabolism as a therapeutic target in cutaneous melanoma. |
2017 |
Transl Res |
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Sphingosine-1-phosphate is involved in inflammatory reactions in patients with Graves' orbitopathy. |
2017 |
Inflamm. Res. |
pmid:28364200
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FTY720-derivatives do not induce FTY720-like lymphopenia. |
2017 |
J. Pharmacol. Sci. |
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Endothelial glycocalyx as a critical signalling platform integrating the extracellular haemodynamic forces and chemical signalling. |
2017 |
J. Cell. Mol. Med. |
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Sphingosine-1-phosphate and its receptors in anti-neutrophil cytoplasmic antibody-associated vasculitis. |
2017 |
Nephrol. Dial. Transplant. |
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Deficiency of the sphingosine-1-phosphate lyase SGPL1 is associated with congenital nephrotic syndrome and congenital adrenal calcifications. |
2017 |
Hum. Mutat. |
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Reduction of Pertussis Inflammatory Pathology by Therapeutic Treatment With Sphingosine-1-Phosphate Receptor Ligands by a Pertussis Toxin-Insensitive Mechanism. |
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J. Infect. Dis. |
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Sphingosine-1 phosphate promotes intestinal epithelial cell proliferation via S1PR2. |
2017 |
Front Biosci (Landmark Ed) |
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High density lipoprotein (HDL)-associated sphingosine 1-phosphate (S1P) inhibits macrophage apoptosis by stimulating STAT3 activity and survivin expression. |
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Atherosclerosis |
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Epithelial cell extrusion: Pathways and pathologies. |
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Semin. Cell Dev. Biol. |
pmid:27212253
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Phytosphingosine-1-phosphate and epidermal growth factor synergistically restore extracellular matrix in human dermal fibroblasts in vitro and in vivo. |
2017 |
Int. J. Mol. Med. |
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Regeneration of glycocalyx by heparan sulfate and sphingosine 1-phosphate restores inter-endothelial communication. |
2017 |
PLoS ONE |
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Sphingosine 1-phosphate alleviates Coxsackievirus B3-induced myocarditis by increasing invariant natural killer T cells. |
2017 |
Exp. Mol. Pathol. |
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Obesity-stimulated aldosterone release is not related to an S1P-dependent mechanism. |
2017 |
J. Endocrinol. |
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High-Density Lipoprotein Regulation of Mitochondrial Function. |
2017 |
Adv. Exp. Med. Biol. |
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Gene expression of sphingolipid metabolism pathways is altered in hidradenitis suppurativa. |
2017 |
J. Am. Acad. Dermatol. |
pmid:28551069
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Lymphatic endothelial S1P promotes mitochondrial function and survival in naive T cells. |
2017 |
Nature |
pmid:28538737
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A Brain-Region-Specific Neural Pathway Regulating Germinal Matrix Angiogenesis. |
2017 |
Dev. Cell |
pmid:28535372
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Sphingosine-1-Phosphate Prevents Egress of Hematopoietic Stem Cells From Liver to Reduce Fibrosis. |
2017 |
Gastroenterology |
pmid:28363640
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Sphingosine-1-Phosphate Metabolism and Its Role in the Development of Inflammatory Bowel Disease. |
2017 |
Int J Mol Sci |
pmid:28362332
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Impairment of the Ability of HDL From Patients With Metabolic Syndrome but Without Diabetes Mellitus to Activate eNOS: Correction by S1P Enrichment. |
2017 |
Arterioscler. Thromb. Vasc. Biol. |
pmid:28360087
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Gusman DH and Shoemake C |
Evaluation and Optimization of designed Sphingosine-1-Phosphate (S1P) Receptor Subtype 1 Modulators for the Management of Multiple Sclerosis. |
2017 |
Yale J Biol Med |
pmid:28356890
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Sphingosine 1-phosphate signaling through its receptor S1P promotes chromosome segregation and mitotic progression. |
2017 |
Sci Signal |
pmid:28351953
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Kim HJ et al. |
Novel involvement of RhebL1 in sphingosylphosphorylcholine-induced keratin phosphorylation and reorganization: Binding to and activation of AKT1. |
2017 |
Oncotarget |
pmid:28209923
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Ceramide synthase 2 facilitates S1P-dependent egress of thymocytes into the circulation in mice. |
2017 |
Eur. J. Immunol. |
pmid:28198542
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Bruno M et al. |
Sphingosine 1-phosphate signaling axis mediates fibroblast growth factor 2-induced proliferation and survival of murine auditory neuroblasts. |
2017 |
Biochim. Biophys. Acta |
pmid:28188805
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Analysis of sphingolipids in human corneal fibroblasts from normal and keratoconus patients. |
2017 |
J. Lipid Res. |
pmid:28188148
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