sphingosine

sphingosine is a lipid of Sphingolipids (SP) class.

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There are no associated biomedical information in the current reference collection.

Current reference collection contains 26061 references associated with sphingosine in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

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Authors Title Published Journal PubMed Link
van der Weyden L et al. Genome-wide in vivo screen identifies novel host regulators of metastatic colonization. 2017 Nature pmid:28052056
Lima S et al. Sphingosine and Sphingosine Kinase 1 Involvement in Endocytic Membrane Trafficking. 2017 J. Biol. Chem. pmid:28049734
Ogle ME et al. Sphingosine-1-Phosphate Receptor-3 Supports Hematopoietic Stem and Progenitor Cell Residence Within the Bone Marrow Niche. 2017 Stem Cells pmid:28026131
Fang V et al. Gradients of the signaling lipid S1P in lymph nodes position natural killer cells and regulate their interferon-γ response. 2017 Nat. Immunol. pmid:27841869
Wang R et al. Hepatic Stellate Cell Selective Disruption of Dynamin-2 GTPase Increases Murine Fibrogenesis through Up-Regulation of Sphingosine-1 Phosphate-Induced Cell Migration. 2017 Am. J. Pathol. pmid:27840081
O'Sullivan S and Dev KK Sphingosine-1-phosphate receptor therapies: Advances in clinical trials for CNS-related diseases. 2017 Neuropharmacology pmid:27825807
Pal SK et al. A phase 2 study of the sphingosine-1-phosphate antibody sonepcizumab in patients with metastatic renal cell carcinoma. 2017 Cancer pmid:27727447
Łukomska A et al. The effect of low levels of lead (Pb) in the blood on levels of sphingosine-1-phosphate (S1P) and expression of S1P receptor 1 in the brain of the rat in the perinatal period. 2017 Chemosphere pmid:27697711
Sánchez DI et al. Melatonin prevents deregulation of the sphingosine kinase/sphingosine 1-phosphate signaling pathway in a mouse model of diethylnitrosamine-induced hepatocellular carcinoma. 2017 J. Pineal Res. pmid:27696512
Katsuta E et al. Doxorubicin effect is enhanced by sphingosine-1-phosphate signaling antagonist in breast cancer. 2017 J. Surg. Res. pmid:29078883
Yang J et al. C2-ceramide influences alveolar epithelial barrier function by downregulating Zo-1, occludin and claudin-4 expression. 2017 Toxicol. Mech. Methods pmid:28052715
Khodorova A et al. The TrkA receptor mediates experimental thermal hyperalgesia produced by nerve growth factor: Modulation by the p75 neurotrophin receptor. 2017 Neuroscience pmid:27826102
Mendelson K et al. The ceramide synthase 2b gene mediates genomic sensing and regulation of sphingosine levels during zebrafish embryogenesis. 2017 Elife pmid:28956531
Baek S et al. DJ-1 Regulates Differentiation of Human Mesenchymal Stem Cells into Smooth Muscle-like Cells in Response to Sphingosylphosphorylcholine. 2017 Proteomics pmid:28949093
Smith P et al. Sphingosine 1-Phosphate Signaling and Its Pharmacological Modulation in Allogeneic Hematopoietic Stem Cell Transplantation. 2017 Int J Mol Sci pmid:28934113
Jiang R et al. Protein kinase Cα stimulates hypoxia‑induced pulmonary artery smooth muscle cell proliferation in rats through activating the extracellular signal‑regulated kinase 1/2 pathway. 2017 Mol Med Rep pmid:28901444
Anjum I et al. Enhancement of S1P-induced contractile response in detrusor smooth muscle of rats having cystitis. 2017 Eur. J. Pharmacol. pmid:28882559
Pierucci F et al. Non-dioxin-like organic toxicant PCB153 modulates sphingolipid metabolism in liver progenitor cells: its role in Cx43-formed gap junction impairment. 2017 Arch. Toxicol. pmid:27318803
Roch L et al. High-Resolution Expression Profiling of Peripheral Blood CD8 Cells in Patients with Multiple Sclerosis Displays Fingolimod-Induced Immune Cell Redistribution. 2017 Mol. Neurobiol. pmid:27631876
Rice TC et al. Sphingosine rescues aged mice from pulmonary pseudomonas infection. 2017 J. Surg. Res. pmid:29078905
Vu TM et al. Mfsd2b is essential for the sphingosine-1-phosphate export in erythrocytes and platelets. 2017 Nature pmid:29045386
Becker KA et al. Neutrophils Kill Reactive Oxygen Species-Resistant Pseudomonas aeruginosa by Sphingosine. 2017 Cell. Physiol. Biochem. pmid:29040968
Onuma T et al. Sphingosine 1-phosphate (S1P) suppresses the collagen-induced activation of human platelets via S1P4 receptor. 2017 Thromb. Res. pmid:28609704
Meissner A S1PR (Sphingosine-1-Phosphate Receptor) Signaling in the Regulation of Vascular Tone and Blood Pressure: Is S1PR1 Doing the Trick? 2017 Hypertension pmid:28607129
Cingolani F et al. Jaspine B induces nonapoptotic cell death in gastric cancer cells independently of its inhibition of ceramide synthase. 2017 J. Lipid Res. pmid:28572516
Grassmé H et al. β1-Integrin Accumulates in Cystic Fibrosis Luminal Airway Epithelial Membranes and Decreases Sphingosine, Promoting Bacterial Infections. 2017 Cell Host Microbe pmid:28552668
Alqinyah M et al. Regulator of G Protein Signaling 10 (Rgs10) Expression Is Transcriptionally Silenced in Activated Microglia by Histone Deacetylase Activity. 2017 Mol. Pharmacol. pmid:28031332
Seo Y et al. Sphingosine-1-phosphate is involved in inflammatory reactions in patients with Graves' orbitopathy. 2017 Inflamm. Res. pmid:28364200
Segura-Ulate I et al. FTY720-derivatives do not induce FTY720-like lymphopenia. 2017 J. Pharmacol. Sci. pmid:28363412
Schumacher F et al. The sphingosine 1-phosphate breakdown product, (2)-hexadecenal, forms protein adducts and glutathione conjugates in vitro. 2017 J. Lipid Res. pmid:28588048
Kitchen SA and Weis VM The sphingosine rheostat is involved in the cnidarian heat stress response but not necessarily in bleaching. 2017 J. Exp. Biol. pmid:28250108
Zeng Y Endothelial glycocalyx as a critical signalling platform integrating the extracellular haemodynamic forces and chemical signalling. 2017 J. Cell. Mol. Med. pmid:28211170
Sun XJ et al. Sphingosine-1-phosphate and its receptors in anti-neutrophil cytoplasmic antibody-associated vasculitis. 2017 Nephrol. Dial. Transplant. pmid:28206609
Ebenezer DL et al. Epigenetic regulation of pro-inflammatory cytokine secretion by sphingosine 1-phosphate (S1P) in acute lung injury: Role of S1P lyase. 2017 Adv Biol Regul pmid:27720306
Feuerborn R et al. High density lipoprotein (HDL)-associated sphingosine 1-phosphate (S1P) inhibits macrophage apoptosis by stimulating STAT3 activity and survivin expression. 2017 Atherosclerosis pmid:28038379
Chang N et al. HuR mediates motility of human bone marrow-derived mesenchymal stem cells triggered by sphingosine 1-phosphate in liver fibrosis. 2017 J. Mol. Med. pmid:27543493
Kwon SB et al. Phytosphingosine-1-phosphate and epidermal growth factor synergistically restore extracellular matrix in human dermal fibroblasts in vitro and in vivo. 2017 Int. J. Mol. Med. pmid:28204807
Wang M et al. Automated tracking and quantification of angiogenic vessel formation in 3D microfluidic devices. 2017 PLoS ONE pmid:29136008
Tran HB et al. Disrupted epithelial/macrophage crosstalk via Spinster homologue 2-mediated S1P signaling may drive defective macrophage phagocytic function in COPD. 2017 PLoS ONE pmid:29112690
Vijayan M et al. Sphingosine 1-Phosphate Lyase Enhances the Activation of IKKε To Promote Type I IFN-Mediated Innate Immune Responses to Influenza A Virus Infection. 2017 J. Immunol. pmid:28600291
White CR et al. High-Density Lipoprotein Regulation of Mitochondrial Function. 2017 Adv. Exp. Med. Biol. pmid:28551800
Dany M and Elston D Gene expression of sphingolipid metabolism pathways is altered in hidradenitis suppurativa. 2017 J. Am. Acad. Dermatol. pmid:28551069
Turner VM and Mabbott NA Ageing adversely affects the migration and function of marginal zone B cells. 2017 Immunology pmid:28369800
Müller J et al. Differential S1P Receptor Profiles on M1- and M2-Polarized Macrophages Affect Macrophage Cytokine Production and Migration. 2017 Biomed Res Int pmid:28367448
King A et al. Sphingosine-1-Phosphate Prevents Egress of Hematopoietic Stem Cells From Liver to Reduce Fibrosis. 2017 Gastroenterology pmid:28363640
Wollny T et al. Sphingosine-1-Phosphate Metabolism and Its Role in the Development of Inflammatory Bowel Disease. 2017 Int J Mol Sci pmid:28362332
Kim HJ et al. Novel involvement of RhebL1 in sphingosylphosphorylcholine-induced keratin phosphorylation and reorganization: Binding to and activation of AKT1. 2017 Oncotarget pmid:28209923
Serafimidis I et al. Pancreas lineage allocation and specification are regulated by sphingosine-1-phosphate signalling. 2017 PLoS Biol. pmid:28248965
Lee HM et al. Oncogenic S1P signalling in EBV-associated nasopharyngeal carcinoma activates AKT and promotes cell migration through S1P receptor 3. 2017 J. Pathol. pmid:28240350
Fujii A et al. Selective Absorption of Dietary Sphingoid Bases from the Intestine via Efflux by P-Glycoprotein in Rats. 2017 J. Nutr. Sci. Vitaminol. pmid:28367925