| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Taki T et al. | A ganglioside of rat ascites hepatoma AH 7974F cells. Occurrence of a novel disialoganglioside (GD1 alpha) with a unique N-acetylneuraminosyl (alpha 2-6)-N-acetylgalactosamine structure. | 1986 | J. Biol. Chem. | pmid:3949760 |
| Merrill AH and Wang E | Biosynthesis of long-chain (sphingoid) bases from serine by LM cells. Evidence for introduction of the 4-trans-double bond after de novo biosynthesis of N-acylsphinganine(s). | 1986 | J. Biol. Chem. | pmid:3081509 |
| Hannun YA et al. | Sphingosine inhibition of agonist-dependent secretion and activation of human platelets implies that protein kinase C is a necessary and common event of the signal transduction pathways. | 1987 | J. Biol. Chem. | pmid:3115982 |
| Nutter LM et al. | Induction of virus enzymes by phorbol esters and n-butyrate in Epstein-Barr virus genome-carrying Raji cells. | 1987 | Cancer Res. | pmid:3038311 |
| Yasugi E et al. | Branched long chain bases in cerebrosides of the guinea pig Harderian gland. | 1987 | J. Biochem. | pmid:3448092 |
| Bouchon B et al. | Selective enrichment of phytosphingosine in glycosphingolipids of isolated human thyrocytes as compared to the whole thyroid. | 1987 | Biochem. Biophys. Res. Commun. | pmid:3566758 |
| Pittet D et al. | Nonselective inhibition of neutrophil functions by sphinganine. | 1987 | J. Biol. Chem. | pmid:3038865 |
| Hope MJ and Cullis PR | Lipid asymmetry induced by transmembrane pH gradients in large unilamellar vesicles. | 1987 | J. Biol. Chem. | pmid:3558410 |
| Sripada PK et al. | Partial synthesis and properties of a series of N-acyl sphingomyelins. | 1987 | J. Lipid Res. | pmid:3611973 |
| Ichioka T et al. | Hematopoietic cell transplantation in murine globoid cell leukodystrophy (the twitcher mouse): effects on levels of galactosylceramidase, psychosine, and galactocerebrosides. | 1987 | Proc. Natl. Acad. Sci. U.S.A. | pmid:2884662 |
| Goda S et al. | Hydrolysis of galactosylsphingosine and lactosylsphingosine by beta-galactosidases in human brain and cultured fibroblasts. | 1987 | Biochim. Biophys. Acta | pmid:3111543 |
| Hannun YA and Bell RM | Lysosphingolipids inhibit protein kinase C: implications for the sphingolipidoses. | 1987 | Science | pmid:3101176 |
| Kobayashi T et al. | Globoid cell leukodystrophy is a generalized galactosylsphingosine (psychosine) storage disease. | 1987 | Biochem. Biophys. Res. Commun. | pmid:3579916 |
| Ichioka T et al. | Simultaneous determination of psychosine and cerebrosides. | 1987 | Anal. Biochem. | pmid:3674406 |
| Shinoda H et al. | Accumulation of galactosylsphingosine (psychosine) in the twitcher mouse: determination by HPLC. | 1987 | J. Neurochem. | pmid:3585345 |
| McIntyre TM et al. | Protein kinase C activity appears to be required for the synthesis of platelet-activating factor and leukotriene B4 by human neutrophils. | 1987 | J. Biol. Chem. | pmid:2824456 |
| Vaccarino F et al. | Ganglioside inhibition of glutamate-mediated protein kinase C translocation in primary cultures of cerebellar neurons. | 1987 | Proc. Natl. Acad. Sci. U.S.A. | pmid:2825205 |
| Osiecki-Newman K et al. | Human acid beta-glucosidase: use of inhibitors, alternative substrates and amphiphiles to investigate the properties of the normal and Gaucher disease active sites. | 1987 | Biochim. Biophys. Acta | pmid:2956992 |
| Bazzi MD and Nelsestuen GL | Mechanism of protein kinase C inhibition by sphingosine. | 1987 | Biochem. Biophys. Res. Commun. | pmid:3606616 |
| Inagaki F et al. | Analysis of NMR spectra of sugar chains of glycolipids by multiple relayed COSY and 2D homonuclear Hartman-Hahn spectroscopy. | 1987 | FEBS Lett. | pmid:3803612 |
| Madden TD et al. | Modelling the biological membrane. | 1987 | Biochem. Soc. Trans. | pmid:3556743 |
| Wertz PW and Downing DT | Covalently bound omega-hydroxyacylsphingosine in the stratum corneum. | 1987 | Biochim. Biophys. Acta | pmid:3790600 |
| Wilson E et al. | Protein kinase C inhibition by sphingoid long-chain bases: effects on secretion in human neutrophils. | 1987 | Arch. Biochem. Biophys. | pmid:2825597 |
| Burgoyne RD et al. | A major role for protein kinase C in calcium-activated exocytosis in permeabilised adrenal chromaffin cells. | 1988 | FEBS Lett. | pmid:3169247 |
| Hamanaka S et al. | Occurrence of galactosylceramide in pig epidermal cells. | 1988 | Biochim. Biophys. Acta | pmid:3401502 |
| Connor JA et al. | Sustained dendritic gradients of Ca2+ induced by excitatory amino acids in CA1 hippocampal neurons. | 1988 | Science | pmid:2452481 |
| Lambeth JD et al. | Sphinganine effects on chemoattractant-induced diacylglycerol generation, calcium fluxes, superoxide production, and on cell viability in the human neutrophil. Delivery of sphinganine with bovine serum albumin minimizes cytotoxicity without affecting inhibition of the respiratory burst. | 1988 | J. Biol. Chem. | pmid:2831206 |
| Merrill AH et al. | Quantitation of free sphingosine in liver by high-performance liquid chromatography. | 1988 | Anal. Biochem. | pmid:3407935 |
| Igisu H et al. | Inhibition of cytochrome c oxidase and hemolysis caused by lysosphingolipids. | 1988 | Lipids | pmid:2840545 |
| Wahl M and Carpenter G | Regulation of epidermal growth factor-stimulated formation of inositol phosphates in A-431 cells by calcium and protein kinase C. | 1988 | J. Biol. Chem. | pmid:3259577 |
| Fan XD et al. | Interferon-gamma-induced transcriptional activation is mediated by protein kinase C. | 1988 | Proc. Natl. Acad. Sci. U.S.A. | pmid:3134657 |
| Shu C and Selmanoff M | Phorbol esters potentiate rapid dopamine release from median eminence and striatal synaptosomes. | 1988 | Endocrinology | pmid:3131121 |
| Wilson E et al. | Modulation of the free sphingosine levels in human neutrophils by phorbol esters and other factors. | 1988 | J. Biol. Chem. | pmid:3132460 |
| Winicov I and Gershengorn MC | Sphingosine inhibits thyrotropin-releasing hormone binding to pituitary cells by a mechanism independent of protein kinase C. | 1988 | J. Biol. Chem. | pmid:3137221 |
| Trinchera M et al. | Different metabolic recycling of the lipid components of exogenous sulphatide in human fibroblasts. | 1988 | Biochem. J. | pmid:3415659 |
| Canonico PL et al. | Phorbol esters attenuate glutamate-stimulated inositol phospholipid hydrolysis in neuronal cultures. | 1988 | J. Neurochem. | pmid:2901459 |
| Phatak PD et al. | Protein kinase C modulates actin conformation in human T lymphocytes. | 1988 | J. Immunol. | pmid:3262672 |
| Linnebjerg H et al. | Inhibition by amiloride and by Na+-depletion of A23187-stimulated arachidonic acid and histamine release from rat mast cells. | 1988 | FEBS Lett. | pmid:2461320 |
| Tyagi SR et al. | Phorbol myristate acetate (PMA) augments chemoattractant-induced diglyceride generation in human neutrophils but inhibits phosphoinositide hydrolysis. Implications for the mechanism of PMA priming of the respiratory burst. | 1988 | J. Biol. Chem. | pmid:2843513 |
| Civan MM et al. | Insulin and phorbol ester stimulate conductive Na+ transport through a common pathway. | 1988 | Proc. Natl. Acad. Sci. U.S.A. | pmid:3277184 |
| Weikel CS et al. | Phorbol esters specifically enhance the cytolytic activity of Entamoeba histolytica. | 1988 | Infect. Immun. | pmid:2897334 |
| Hall FL et al. | Suppression of nerve growth factor-directed neurite outgrowth in PC12 cells by sphingosine, an inhibitor of protein kinase C. | 1988 | J. Biol. Chem. | pmid:3162237 |
| Faucher M et al. | Regulation of the epidermal growth factor receptor phosphorylation state by sphingosine in A431 human epidermoid carcinoma cells. | 1988 | J. Biol. Chem. | pmid:3162730 |
| Rider LG et al. | Phorbol diesters and dioctanoylglycerol stimulate accumulation of both diacylglycerols and alkylacylglycerols in human neutrophils. | 1988 | J. Immunol. | pmid:2826587 |
| Tanaka K et al. | The twitcher mouse: accumulation of galactosylsphingosine and pathology of the sciatic nerve. | 1988 | Brain Res. | pmid:3409017 |
| Kobayashi T et al. | Free sphingoid bases in normal murine tissues. | 1988 | Eur. J. Biochem. | pmid:3350021 |
| Medlock KA and Merrill AH | Rapid turnover of sphingosine synthesized de novo from [14C]serine by Chinese hamster ovary cells. | 1988 | Biochem. Biophys. Res. Commun. | pmid:3143361 |
| Malinow R et al. | Persistent protein kinase activity underlying long-term potentiation. | 1988 | Nature | pmid:2847049 |
| Kobayashi T et al. | Infantile and fetal globoid cell leukodystrophy: analysis of galactosylceramide and galactosylsphingosine. | 1988 | Ann. Neurol. | pmid:3239954 |
| Jefferson AB and Schulman H | Sphingosine inhibits calmodulin-dependent enzymes. | 1988 | J. Biol. Chem. | pmid:2844804 |
| Grove DS and Mastro AM | Prevention of the TPA-mediated down-regulation of protein kinase C. | 1988 | Biochem. Biophys. Res. Commun. | pmid:3348799 |
| Slivka SR et al. | Alpha 1-adrenergic receptors promote phosphatidylcholine hydrolysis in MDCK-D1 cells. A mechanism for rapid activation of protein kinase C. | 1988 | J. Biol. Chem. | pmid:2842326 |
| Northwood IC and Davis RJ | Activation of the epidermal growth factor receptor tyrosine protein kinase in the absence of receptor oligomerization. | 1988 | J. Biol. Chem. | pmid:2836384 |
| Chow SC et al. | Phosphoinositide breakdown and evidence for protein kinase C involvement during human NK killing. | 1988 | Cell. Immunol. | pmid:2836072 |
| Mitsuo K et al. | A high-performance liquid chromatographic assay for acid ceramidase activity in cultured fibroblasts from patients with Farber's disease and from controls. | 1988 | Clin. Chim. Acta | pmid:3383428 |
| Davis RJ et al. | Two alternative mechanisms control the interconversion of functional states of the epidermal growth factor receptor. | 1988 | J. Biol. Chem. | pmid:3258597 |
| Bruzik KS | Conformation of the polar headgroup of sphingomyelin and its analogues. | 1988 | Biochim. Biophys. Acta | pmid:3355820 |
| Siffert W and Akkerman JW | Protein kinase C enhances Ca2+ mobilization in human platelets by activating Na+/H+ exchange. | 1988 | J. Biol. Chem. | pmid:2831223 |
| Sanchez A et al. | Thrombin-induced changes of intracellular [Ca2+] and pH in human platelets. Cytoplasmic alkalinization is not a prerequisite for calcium mobilization. | 1988 | Biochim. Biophys. Acta | pmid:2831984 |
| Hirabayashi Y et al. | A novel glycosphingolipid hydrolyzing enzyme, glycosphingolipid ceramide deacylase, which cleaves the linkage between the fatty acid and sphingosine base in glycosphingolipids. | 1988 | J. Biochem. | pmid:3360750 |
| Bell RM et al. | Protein kinase C regulation by sphingosine/lysosphingolipids. | 1988 | Cold Spring Harb. Symp. Quant. Biol. | pmid:3076075 |
| Gupta AK et al. | Sphingosine inhibits phorbol ester-induced inflammation, ornithine decarboxylase activity, and activation of protein kinase C in mouse skin. | 1988 | J. Invest. Dermatol. | pmid:3171222 |
| Badwey JA et al. | Synergistic stimulation of neutrophils. Possible involvement of 5-hydroxy-6,8,11,14-eicosatetraenoate in superoxide release. | 1988 | J. Biol. Chem. | pmid:2830263 |
| Hwong CL et al. | Phorbol ester transiently increases topoisomerase I mRNA levels in human skin fibroblasts. | 1989 | J. Biol. Chem. | pmid:2549041 |
| Bedoy CA and Mobley PL | Astrocyte morphology altered by 1-(5-isoquinolinylsulfonyl) 2-methyl piperazine (H-7) and other protein kinase inhibitors. | 1989 | Brain Res. | pmid:2548656 |
| Messmer TO et al. | Sphingolipid biosynthesis by rat liver cells: effects of serine, fatty acids and lipoproteins. | 1989 | J. Nutr. | pmid:2495341 |
| Weiss BA et al. | Defining the role of protein kinase C in epinephrine- and bradykinin-stimulated arachidonic acid metabolism in Madin-Darby canine kidney cells. | 1989 | Mol. Pharmacol. | pmid:2549387 |
| Reinhold DS and Neet KE | The lack of a role for protein kinase C in neurite extension and in the induction of ornithine decarboxylase by nerve growth factor in PC12 cells. | 1989 | J. Biol. Chem. | pmid:2914963 |
| Krishnamurthi S et al. | Weak inhibition of protein kinase C coupled with various non-specific effects make sphingosine an unsuitable tool in platelet signal transduction studies. | 1989 | Biochim. Biophys. Acta | pmid:2492201 |
| Gordon PR and Gilchrest BA | Human melanogenesis is stimulated by diacylglycerol. | 1989 | J. Invest. Dermatol. | pmid:2794552 |
| Bixby JL | Protein kinase C is involved in laminin stimulation of neurite outgrowth. | 1989 | Neuron | pmid:2561968 |
| Stinavage P and Spitznagel JK | Oxygen-independent antimicrobial action in sphingosine-treated neutrophils. | 1989 | J. Immunol. Methods | pmid:2557368 |
| Gerrard JM et al. | A role for protein kinase C in the membrane fusion necessary for platelet granule secretion. | 1989 | Blood | pmid:2553164 |
| Martinez R and Gillies RJ | Dimethylsulfoxide modifies the sensitivity of BALB/c-3T3 cells to the activation of Na+/H+ exchange by phorbol esters. | 1989 | J. Cell. Physiol. | pmid:2540208 |
| Ware JA et al. | Response of aequorin-loaded platelets to activators of protein kinase C. | 1989 | Am. J. Physiol. | pmid:2912135 |
| Bertorello A and Aperia A | Na+-K+-ATPase is an effector protein for protein kinase C in renal proximal tubule cells. | 1989 | Am. J. Physiol. | pmid:2537029 |
| Gillies RJ et al. | Sphingosine inhibits phorbol 12-myristate 13-acetate-, but not serum-induced, activation of Na+/H+ exchange in mammalian cells. | 1989 | J. Cell. Physiol. | pmid:2540207 |
| Conn PJ et al. | Inhibitors of protein kinase C prevent enhancement of calcium current and action potentials in peptidergic neurons of Aplysia. | 1989 | J. Neurosci. | pmid:2918372 |
| Mills GB et al. | Role of protein kinase C in interleukin 1, anti-T3, and mitogenic lectin-induced interleukin 2 secretion. | 1989 | J. Cell. Physiol. | pmid:2808540 |
| Van Veldhoven PP et al. | A facile enzymatic synthesis of sphingosine-1-phosphate and dihydrosphingosine-1-phosphate. | 1989 | J. Lipid Res. | pmid:2754341 |
| Leyravaud S et al. | Biosynthesis of paf-acether. X. Phorbol myristate acetate-induced paf-acether biosynthesis and acetyltransferase activation in human neutrophils. | 1989 | J. Immunol. | pmid:2732470 |
| Toda K et al. | Accumulation of lysosulfatide (sulfogalactosylsphingosine) in tissues of a boy with metachromatic leukodystrophy. | 1989 | Biochem. Biophys. Res. Commun. | pmid:2539117 |
| Vartanian T et al. | Phosphorylation of myelin basic protein in intact oligodendrocytes: inhibition by galactosylsphingosine and cyclic AMP. | 1989 | Glia | pmid:2478466 |
| Tanaka K et al. | The twitcher mouse: accumulation of galactosylsphingosine and pathology of the central nervous system. | 1989 | Brain Res. | pmid:2706492 |
| Van Veldhoven PP et al. | Enzymatic quantification of sphingosine in the picomole range in cultured cells. | 1989 | Anal. Biochem. | pmid:2559626 |
| Conkling PR et al. | Sphingosine inhibits monocyte tissue factor-initiated coagulation by altering factor VII binding. | 1989 | J. Biol. Chem. | pmid:2808383 |
| Reddy SS and Kahn CR | Epidermal growth factor receptor defects in leprechaunism. A multiple growth factor-resistant syndrome. | 1989 | J. Clin. Invest. | pmid:2808704 |
| Draznin B et al. | Mechanism of insulin resistance induced by sustained levels of cytosolic free calcium in rat adipocytes. | 1989 | Endocrinology | pmid:2551647 |
| O'Flaherty JT and Jacobson D | Protein kinase C blockers and neutrophil receptors for leukotriene B4. | 1989 | Biochem. Biophys. Res. Commun. | pmid:2551291 |
| Bottega R et al. | Inhibition of protein kinase C by sphingosine correlates with the presence of positive charge. | 1989 | Biochem. Biophys. Res. Commun. | pmid:2803286 |
| Petty HR | Regulation of RAW264 macrophage morphology and spreading: studies with protein kinase C activators, inhibitors and a cyclic AMP analog. | 1989 | Biochim. Biophys. Acta | pmid:2547441 |
| Wedegaertner PB and Gill GN | Activation of the purified protein tyrosine kinase domain of the epidermal growth factor receptor. | 1989 | J. Biol. Chem. | pmid:2661557 |
| Mattila P et al. | Protein kinase C is crucial in signal transduction during IFN-gamma induction in endothelial cells. | 1989 | FEBS Lett. | pmid:2546804 |
| Szamel M et al. | Activation signals in human lymphocytes. Incorporation of polyunsaturated fatty acids into plasma membrane phospholipids regulates IL-2 synthesis via sustained activation of protein kinase C. | 1989 | J. Immunol. | pmid:2530278 |
| Sparling ML et al. | Analysis of membrane lipids by 500 MHz 1H NMR. | 1989 | Anal. Biochem. | pmid:2729581 |
| Bader MF et al. | A reassessment of guanine nucleotide effects on catecholamine secretion from permeabilized adrenal chromaffin cells. | 1989 | J. Biol. Chem. | pmid:2674132 |
| Agam G et al. | Thrombin-induced platelet aggregation is affected by external Na+ independently of the Na+/H+ exchange. | 1989 | FEBS Lett. | pmid:2538349 |
| Merrill AH and Stevens VL | Modulation of protein kinase C and diverse cell functions by sphingosine--a pharmacologically interesting compound linking sphingolipids and signal transduction. | 1989 | Biochim. Biophys. Acta | pmid:2643437 |
| Hannun YA and Bell RM | Functions of sphingolipids and sphingolipid breakdown products in cellular regulation. | 1989 | Science | pmid:2643164 |
| Sakane F et al. | Different effects of sphingosine, R59022 and anionic amphiphiles on two diacylglycerol kinase isozymes purified from porcine thymus cytosol. | 1989 | FEBS Lett. | pmid:2551742 |
sphingosine
sphingosine is a lipid of Sphingolipids (SP) class.
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