sphingosine

sphingosine is a lipid of Sphingolipids (SP) class.

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There are no associated biomedical information in the current reference collection.

Current reference collection contains 26061 references associated with sphingosine in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

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Authors Title Published Journal PubMed Link
Myśliwiec H et al. Increase in circulating sphingosine-1-phosphate and decrease in ceramide levels in psoriatic patients. 2017 Arch. Dermatol. Res. pmid:27988894
Powell JA et al. Targeting sphingosine kinase 1 induces MCL1-dependent cell death in acute myeloid leukemia. 2017 Blood pmid:27956387
Miyabe C et al. A sphingosine 1-phosphate receptor agonist ameliorates animal model of vasculitis. 2017 Inflamm. Res. pmid:27942751
Zhao Z et al. Characterization of the Anticoagulant and Antithrombotic Properties of the Sphingosine 1-Phosphate Mimetic FTY720. 2017 Acta Haematol. pmid:27802432
González-Fernández B et al. Inhibition of the SphK1/S1P signaling pathway by melatonin in mice with liver fibrosis and human hepatic stellate cells. 2017 Biofactors pmid:27801960
Mendelson K et al. The ceramide synthase 2b gene mediates genomic sensing and regulation of sphingosine levels during zebrafish embryogenesis. 2017 Elife pmid:28956531
Jiang S et al. C2-ceramide enhances sorafenib-induced caspase-dependent apoptosis via PI3K/AKT/mTOR and Erk signaling pathways in HCC cells. 2017 Appl. Microbiol. Biotechnol. pmid:27807662
Baek S et al. DJ-1 Regulates Differentiation of Human Mesenchymal Stem Cells into Smooth Muscle-like Cells in Response to Sphingosylphosphorylcholine. 2017 Proteomics pmid:28949093
Smith P et al. Sphingosine 1-Phosphate Signaling and Its Pharmacological Modulation in Allogeneic Hematopoietic Stem Cell Transplantation. 2017 Int J Mol Sci pmid:28934113
Mitroi DN et al. SGPL1 (sphingosine phosphate lyase 1) modulates neuronal autophagy via phosphatidylethanolamine production. 2017 Autophagy pmid:28521611
Pierucci F et al. Vitamin D protects against Aβ peptide cytotoxicity in differentiated human neuroblastoma SH- SY5Y cells: A role for S1P1/p38MAPK/ATF4 axis. 2017 Neuropharmacology pmid:28077289
Leo A et al. The Sphingosine 1-Phosphate Signaling Pathway in Epilepsy: A Possible Role for the Immunomodulator Drug Fingolimod in Epilepsy Treatment. 2017 CNS Neurol Disord Drug Targets pmid:27823573
Roch L et al. High-Resolution Expression Profiling of Peripheral Blood CD8 Cells in Patients with Multiple Sclerosis Displays Fingolimod-Induced Immune Cell Redistribution. 2017 Mol. Neurobiol. pmid:27631876
Natarajan V et al. Expression profiling of genes regulated by sphingosine kinase1 signaling in a murine model of hyperoxia induced neonatal bronchopulmonary dysplasia. 2017 BMC Genomics pmid:28851267
Hajny S and Christoffersen C A Novel Perspective on the ApoM-S1P Axis, Highlighting the Metabolism of ApoM and Its Role in Liver Fibrosis and Neuroinflammation. 2017 Int J Mol Sci pmid:28749426
Bertlich M et al. Fingolimod (FTY-720) is Capable of Reversing Tumor Necrosis Factor Induced Decreases in Cochlear Blood Flow. 2017 Otol. Neurotol. pmid:28742634
Kurano M et al. Involvement of Band3 in the efflux of sphingosine 1-phosphate from erythrocytes. 2017 PLoS ONE pmid:28494002
Dany M Sphingosine metabolism as a therapeutic target in cutaneous melanoma. 2017 Transl Res pmid:28528915
Yanagawa D et al. Synthesis and degradation of long-chain base phosphates affect fumonisin B-induced cell death in Arabidopsis thaliana. 2017 J. Plant Res. pmid:28303405
Chen Y et al. Atherosclerotic dyslipidemia revealed by plasma lipidomics on ApoE mice fed a high-fat diet. 2017 Atherosclerosis pmid:28527370
Oh YT et al. DR5 suppression induces sphingosine-1-phosphate-dependent TRAF2 polyubiquitination, leading to activation of JNK/AP-1 and promotion of cancer cell invasion. 2017 Cell Commun. Signal pmid:28482915
Tessema EN et al. Isolation and structural characterization of glucosylceramides from Ethiopian plants by LC/APCI-MS/MS. 2017 J Pharm Biomed Anal pmid:28463779
Fan Q et al. Sphingosine-1-phosphate promotes ovarian cancer cell proliferation by disrupting Hippo signaling. 2017 Oncotarget pmid:28460443
Martin GE et al. Sphingosine's role in epithelial host defense: A natural antimicrobial and novel therapeutic. 2017 Biochimie pmid:28341550
Separovic D et al. Altered Levels of Serum Ceramide, Sphingosine and Sphingomyelin Are Associated with Colorectal Cancer: A Retrospective Pilot Study. 2017 Anticancer Res. pmid:28314284
Patmanathan SN et al. Mechanisms of sphingosine 1-phosphate receptor signalling in cancer. 2017 Cell. Signal. pmid:28302566
Janecke AR et al. Deficiency of the sphingosine-1-phosphate lyase SGPL1 is associated with congenital nephrotic syndrome and congenital adrenal calcifications. 2017 Hum. Mutat. pmid:28181337
Rothhammer V et al. Sphingosine 1-phosphate receptor modulation suppresses pathogenic astrocyte activation and chronic progressive CNS inflammation. 2017 Proc. Natl. Acad. Sci. U.S.A. pmid:28167760
Moritz E et al. Reference intervals for serum sphingosine-1-phosphate in the population-based Study of Health in Pomerania. 2017 Clin. Chim. Acta pmid:28159438
Lin MH et al. Linear ion-trap MS with high-resolution MS reveals structural diversity of 1-O-acylceramide family in mouse epidermis. 2017 J. Lipid Res. pmid:28154204
Jafurulla M et al. Sphingolipids modulate the function of human serotonin receptors: Insights from sphingolipid-deficient cells. 2017 Biochim. Biophys. Acta pmid:27984018
Winkler MS et al. Sphingosine-1-Phosphate: A Potential Biomarker and Therapeutic Target for Endothelial Dysfunction and Sepsis? 2017 Shock pmid:27922551
Al-Jarallah A and Oriowo M The effect of sphingosine-1-phosphate on colonic smooth muscle contractility: Modulation by TNBS-induced colitis. 2017 PLoS ONE pmid:28493876
Gudipaty SA and Rosenblatt J Epithelial cell extrusion: Pathways and pathologies. 2017 Semin. Cell Dev. Biol. pmid:27212253
Du Y et al. Exosomes from Human-Induced Pluripotent Stem Cell-Derived Mesenchymal Stromal Cells (hiPSC-MSCs) Protect Liver against Hepatic Ischemia/ Reperfusion Injury via Activating Sphingosine Kinase and Sphingosine-1-Phosphate Signaling Pathway. 2017 Cell. Physiol. Biochem. pmid:28934733
Kuchler L et al. Elevated intrathymic sphingosine-1-phosphate promotes thymus involution during sepsis. 2017 Mol. Immunol. pmid:28846923
Nicholas SE et al. Unravelling the interplay of sphingolipids and TGF-β signaling in the human corneal stroma. 2017 PLoS ONE pmid:28806736
Meshcheryakova A et al. Sphingosine 1-phosphate signaling in bone remodeling: multifaceted roles and therapeutic potential. 2017 Expert Opin. Ther. Targets pmid:28524744
Ko J et al. Sphingosine-1-Phosphate Mediates Fibrosis in Orbital Fibroblasts in Graves' Orbitopathy. 2017 Invest. Ophthalmol. Vis. Sci. pmid:28492873
Zhang H et al. Ceramide enhances COX-2 expression and VSMC contractile hyperreactivity via ER stress signal activation. 2017 Vascul. Pharmacol. pmid:28797762
Becker S et al. Low sphingosine-1-phosphate plasma levels are predictive for increased mortality in patients with liver cirrhosis. 2017 PLoS ONE pmid:28334008
Karunakaran I and van Echten-Deckert G Sphingosine 1-phosphate - A double edged sword in the brain. 2017 Biochim. Biophys. Acta pmid:28315304
Navarrete A et al. A metabolomic approach shows sphingosine 1-phosphate and lysophospholipids as mediators of the therapeutic effect of liver growth factor in emphysema. 2017 J Pharm Biomed Anal pmid:28314215
Shirakawa H et al. Sphingosine-1-phosphate induces Ca signaling and CXCL1 release via TRPC6 channel in astrocytes. 2017 Glia pmid:28300348
Ren K et al. ApoA-I/SR-BI modulates S1P/S1PR2-mediated inflammation through the PI3K/Akt signaling pathway in HUVECs. 2017 J. Physiol. Biochem. pmid:28181168
Ruiz M et al. HDL-associated ApoM is anti-apoptotic by delivering sphingosine 1-phosphate to S1P1 & S1P3 receptors on vascular endothelium. 2017 Lipids Health Dis pmid:28179022
Moruno-Manchon JF et al. Inhibiting sphingosine kinase 2 mitigates mutant Huntingtin-induced neurodegeneration in neuron models of Huntington disease. 2017 Hum. Mol. Genet. pmid:28175299
Rojas-Canales D et al. Local Sphingosine Kinase 1 Activity Improves Islet Transplantation. 2017 Diabetes pmid:28174291
Abe A et al. Preferential hydrolysis of truncated oxidized glycerophospholipids by lysosomal phospholipase A2. 2017 J. Lipid Res. pmid:27993948
Dela Paz NG et al. Shear stress induces Gα activation independently of G protein-coupled receptor activation in endothelial cells. 2017 Am. J. Physiol., Cell Physiol. pmid:28148497