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Increase in circulating sphingosine-1-phosphate and decrease in ceramide levels in psoriatic patients. |
2017 |
Arch. Dermatol. Res. |
pmid:27988894
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Powell JA et al. |
Targeting sphingosine kinase 1 induces MCL1-dependent cell death in acute myeloid leukemia. |
2017 |
Blood |
pmid:27956387
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Miyabe C et al. |
A sphingosine 1-phosphate receptor agonist ameliorates animal model of vasculitis. |
2017 |
Inflamm. Res. |
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Zhao Z et al. |
Characterization of the Anticoagulant and Antithrombotic Properties of the Sphingosine 1-Phosphate Mimetic FTY720. |
2017 |
Acta Haematol. |
pmid:27802432
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González-Fernández B et al. |
Inhibition of the SphK1/S1P signaling pathway by melatonin in mice with liver fibrosis and human hepatic stellate cells. |
2017 |
Biofactors |
pmid:27801960
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Mendelson K et al. |
The ceramide synthase 2b gene mediates genomic sensing and regulation of sphingosine levels during zebrafish embryogenesis. |
2017 |
Elife |
pmid:28956531
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Jiang S et al. |
C2-ceramide enhances sorafenib-induced caspase-dependent apoptosis via PI3K/AKT/mTOR and Erk signaling pathways in HCC cells. |
2017 |
Appl. Microbiol. Biotechnol. |
pmid:27807662
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Baek S et al. |
DJ-1 Regulates Differentiation of Human Mesenchymal Stem Cells into Smooth Muscle-like Cells in Response to Sphingosylphosphorylcholine. |
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Proteomics |
pmid:28949093
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Sphingosine 1-Phosphate Signaling and Its Pharmacological Modulation in Allogeneic Hematopoietic Stem Cell Transplantation. |
2017 |
Int J Mol Sci |
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Mitroi DN et al. |
SGPL1 (sphingosine phosphate lyase 1) modulates neuronal autophagy via phosphatidylethanolamine production. |
2017 |
Autophagy |
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Pierucci F et al. |
Vitamin D protects against Aβ peptide cytotoxicity in differentiated human neuroblastoma SH- SY5Y cells: A role for S1P1/p38MAPK/ATF4 axis. |
2017 |
Neuropharmacology |
pmid:28077289
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Leo A et al. |
The Sphingosine 1-Phosphate Signaling Pathway in Epilepsy: A Possible Role for the Immunomodulator Drug Fingolimod in Epilepsy Treatment. |
2017 |
CNS Neurol Disord Drug Targets |
pmid:27823573
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Roch L et al. |
High-Resolution Expression Profiling of Peripheral Blood CD8 Cells in Patients with Multiple Sclerosis Displays Fingolimod-Induced Immune Cell Redistribution. |
2017 |
Mol. Neurobiol. |
pmid:27631876
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Natarajan V et al. |
Expression profiling of genes regulated by sphingosine kinase1 signaling in a murine model of hyperoxia induced neonatal bronchopulmonary dysplasia. |
2017 |
BMC Genomics |
pmid:28851267
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Hajny S and Christoffersen C |
A Novel Perspective on the ApoM-S1P Axis, Highlighting the Metabolism of ApoM and Its Role in Liver Fibrosis and Neuroinflammation. |
2017 |
Int J Mol Sci |
pmid:28749426
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Bertlich M et al. |
Fingolimod (FTY-720) is Capable of Reversing Tumor Necrosis Factor Induced Decreases in Cochlear Blood Flow. |
2017 |
Otol. Neurotol. |
pmid:28742634
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Kurano M et al. |
Involvement of Band3 in the efflux of sphingosine 1-phosphate from erythrocytes. |
2017 |
PLoS ONE |
pmid:28494002
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Dany M |
Sphingosine metabolism as a therapeutic target in cutaneous melanoma. |
2017 |
Transl Res |
pmid:28528915
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Yanagawa D et al. |
Synthesis and degradation of long-chain base phosphates affect fumonisin B-induced cell death in Arabidopsis thaliana. |
2017 |
J. Plant Res. |
pmid:28303405
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Chen Y et al. |
Atherosclerotic dyslipidemia revealed by plasma lipidomics on ApoE mice fed a high-fat diet. |
2017 |
Atherosclerosis |
pmid:28527370
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Oh YT et al. |
DR5 suppression induces sphingosine-1-phosphate-dependent TRAF2 polyubiquitination, leading to activation of JNK/AP-1 and promotion of cancer cell invasion. |
2017 |
Cell Commun. Signal |
pmid:28482915
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Tessema EN et al. |
Isolation and structural characterization of glucosylceramides from Ethiopian plants by LC/APCI-MS/MS. |
2017 |
J Pharm Biomed Anal |
pmid:28463779
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Fan Q et al. |
Sphingosine-1-phosphate promotes ovarian cancer cell proliferation by disrupting Hippo signaling. |
2017 |
Oncotarget |
pmid:28460443
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Martin GE et al. |
Sphingosine's role in epithelial host defense: A natural antimicrobial and novel therapeutic. |
2017 |
Biochimie |
pmid:28341550
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Separovic D et al. |
Altered Levels of Serum Ceramide, Sphingosine and Sphingomyelin Are Associated with Colorectal Cancer: A Retrospective Pilot Study. |
2017 |
Anticancer Res. |
pmid:28314284
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Patmanathan SN et al. |
Mechanisms of sphingosine 1-phosphate receptor signalling in cancer. |
2017 |
Cell. Signal. |
pmid:28302566
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Janecke AR et al. |
Deficiency of the sphingosine-1-phosphate lyase SGPL1 is associated with congenital nephrotic syndrome and congenital adrenal calcifications. |
2017 |
Hum. Mutat. |
pmid:28181337
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Sphingosine 1-phosphate receptor modulation suppresses pathogenic astrocyte activation and chronic progressive CNS inflammation. |
2017 |
Proc. Natl. Acad. Sci. U.S.A. |
pmid:28167760
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Reference intervals for serum sphingosine-1-phosphate in the population-based Study of Health in Pomerania. |
2017 |
Clin. Chim. Acta |
pmid:28159438
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Linear ion-trap MS with high-resolution MS reveals structural diversity of 1-O-acylceramide family in mouse epidermis. |
2017 |
J. Lipid Res. |
pmid:28154204
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Jafurulla M et al. |
Sphingolipids modulate the function of human serotonin receptors: Insights from sphingolipid-deficient cells. |
2017 |
Biochim. Biophys. Acta |
pmid:27984018
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Winkler MS et al. |
Sphingosine-1-Phosphate: A Potential Biomarker and Therapeutic Target for Endothelial Dysfunction and Sepsis? |
2017 |
Shock |
pmid:27922551
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Al-Jarallah A and Oriowo M |
The effect of sphingosine-1-phosphate on colonic smooth muscle contractility: Modulation by TNBS-induced colitis. |
2017 |
PLoS ONE |
pmid:28493876
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Gudipaty SA and Rosenblatt J |
Epithelial cell extrusion: Pathways and pathologies. |
2017 |
Semin. Cell Dev. Biol. |
pmid:27212253
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Du Y et al. |
Exosomes from Human-Induced Pluripotent Stem Cell-Derived Mesenchymal Stromal Cells (hiPSC-MSCs) Protect Liver against Hepatic Ischemia/ Reperfusion Injury via Activating Sphingosine Kinase and Sphingosine-1-Phosphate Signaling Pathway. |
2017 |
Cell. Physiol. Biochem. |
pmid:28934733
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Kuchler L et al. |
Elevated intrathymic sphingosine-1-phosphate promotes thymus involution during sepsis. |
2017 |
Mol. Immunol. |
pmid:28846923
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Nicholas SE et al. |
Unravelling the interplay of sphingolipids and TGF-β signaling in the human corneal stroma. |
2017 |
PLoS ONE |
pmid:28806736
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Meshcheryakova A et al. |
Sphingosine 1-phosphate signaling in bone remodeling: multifaceted roles and therapeutic potential. |
2017 |
Expert Opin. Ther. Targets |
pmid:28524744
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Ko J et al. |
Sphingosine-1-Phosphate Mediates Fibrosis in Orbital Fibroblasts in Graves' Orbitopathy. |
2017 |
Invest. Ophthalmol. Vis. Sci. |
pmid:28492873
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Zhang H et al. |
Ceramide enhances COX-2 expression and VSMC contractile hyperreactivity via ER stress signal activation. |
2017 |
Vascul. Pharmacol. |
pmid:28797762
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Becker S et al. |
Low sphingosine-1-phosphate plasma levels are predictive for increased mortality in patients with liver cirrhosis. |
2017 |
PLoS ONE |
pmid:28334008
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Karunakaran I and van Echten-Deckert G |
Sphingosine 1-phosphate - A double edged sword in the brain. |
2017 |
Biochim. Biophys. Acta |
pmid:28315304
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Navarrete A et al. |
A metabolomic approach shows sphingosine 1-phosphate and lysophospholipids as mediators of the therapeutic effect of liver growth factor in emphysema. |
2017 |
J Pharm Biomed Anal |
pmid:28314215
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Shirakawa H et al. |
Sphingosine-1-phosphate induces Ca signaling and CXCL1 release via TRPC6 channel in astrocytes. |
2017 |
Glia |
pmid:28300348
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Ren K et al. |
ApoA-I/SR-BI modulates S1P/S1PR2-mediated inflammation through the PI3K/Akt signaling pathway in HUVECs. |
2017 |
J. Physiol. Biochem. |
pmid:28181168
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Ruiz M et al. |
HDL-associated ApoM is anti-apoptotic by delivering sphingosine 1-phosphate to S1P1 & S1P3 receptors on vascular endothelium. |
2017 |
Lipids Health Dis |
pmid:28179022
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Moruno-Manchon JF et al. |
Inhibiting sphingosine kinase 2 mitigates mutant Huntingtin-induced neurodegeneration in neuron models of Huntington disease. |
2017 |
Hum. Mol. Genet. |
pmid:28175299
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Rojas-Canales D et al. |
Local Sphingosine Kinase 1 Activity Improves Islet Transplantation. |
2017 |
Diabetes |
pmid:28174291
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Abe A et al. |
Preferential hydrolysis of truncated oxidized glycerophospholipids by lysosomal phospholipase A2. |
2017 |
J. Lipid Res. |
pmid:27993948
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Dela Paz NG et al. |
Shear stress induces Gα activation independently of G protein-coupled receptor activation in endothelial cells. |
2017 |
Am. J. Physiol., Cell Physiol. |
pmid:28148497
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