| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Kim S et al. | Accumulation of phosphorylated sphingoid long chain bases results in cell growth inhibition in Saccharomyces cerevisiae. | 2000 | Genetics | pmid:11102354 |
| Murata N et al. | Interaction of sphingosine 1-phosphate with plasma components, including lipoproteins, regulates the lipid receptor-mediated actions. | 2000 | Biochem. J. | pmid:11104690 |
| Nofer JR et al. | Activation of phosphatidylinositol-specific phospholipase C by HDL-associated lysosphingolipid. Involvement in mitogenesis but not in cholesterol efflux. | 2000 | Biochemistry | pmid:11106499 |
| Maurer BJ et al. | Synergistic cytotoxicity in solid tumor cell lines between N-(4-hydroxyphenyl)retinamide and modulators of ceramide metabolism. | 2000 | J. Natl. Cancer Inst. | pmid:11106681 |
| Kimura M et al. | Release of plasminogen activator inhibitor-1 from human astrocytes is regulated by intracellular ceramide. | 2000 | J. Neurosci. Res. | pmid:11107162 |
| Bittman R and Verbicky CA | Methanolysis of sphingomyelin. Toward an epimerization-free methodology for the preparation of D-erythro-sphingosylphosphocholine. | 2000 | J. Lipid Res. | pmid:11108743 |
| Ueda H et al. | Effect of a novel immunosuppressant, FTY720, on allograft survival after renal transplant in rats. | 2000 | Eur Surg Res | pmid:11111172 |
| Böhler T et al. | FTY 720A mediates reduction of lymphocyte counts in human renal allograft recipients by an apoptosis-independent mechanism. | 2000 | Transpl. Int. | pmid:11112021 |
| Xia P et al. | An oncogenic role of sphingosine kinase. | 2000 | Curr. Biol. | pmid:11114522 |
| Tamama K et al. | Extracellular mechanism through the Edg family of receptors might be responsible for sphingosine-1-phosphate-induced regulation of DNA synthesis and migration of rat aortic smooth-muscle cells. | 2001 | Biochem. J. | pmid:11115407 |
| Lei G et al. | New immunosuppressive reagent, FTY 720, spares immunologic memory. | 2000 | Transplant. Proc. | pmid:11119867 |
| Chueh SC et al. | Rescuing acute rejection of rat cardiac allografts with FTY720. | 2000 | Transplant. Proc. | pmid:11119868 |
| Ohba M et al. | Perioperative administration of FTY720 and CTLA4IG in rat heart transplantation. | 2000 | Transplant. Proc. | pmid:11120049 |
| Sugiki H et al. | C2-ceramide induces apoptosis in a human squamous cell carcinoma cell line. | 2000 | Br. J. Dermatol. | pmid:11122015 |
| Hitomi K et al. | Characterization of human recombinant transglutaminase 1 purified from baculovirus-infected insect cells. | 2000 | Biosci. Biotechnol. Biochem. | pmid:11129585 |
| Walev I et al. | Streptolysin O-permeabilized granulocytes shed L-selectin concomitantly with ceramide generation via neutral sphingomyelinase. | 2000 | J. Leukoc. Biol. | pmid:11129654 |
| Kwon YG et al. | Sphingosine 1-phosphate protects human umbilical vein endothelial cells from serum-deprived apoptosis by nitric oxide production. | 2001 | J. Biol. Chem. | pmid:11134047 |
| Kim YK et al. | Differential regulation of protein tyrosine kinase on free radical production, granule enzyme release, and cytokine synthesis by activated murine peritoneal macrophages. | 2001 | Biochem. Pharmacol. | pmid:11137713 |
| Brandts B et al. | Inhibition of muscarinic potassium current by the class III antiarrhythmic drug RP58866 in guinea-pig atrial myocytes. | 2000 | Pacing Clin Electrophysiol | pmid:11139931 |
| Huang MB and Bond VC | Involvement of protein kinase C in HIV-1 gp120-induced apoptosis in primary endothelium. | 2000 | J. Acquir. Immune Defic. Syndr. | pmid:11141237 |
| Sato K et al. | Differential roles of Edg-1 and Edg-5, sphingosine 1-phosphate receptors, in the signaling pathways in C6 glioma cells. | 2000 | Brain Res. Mol. Brain Res. | pmid:11146117 |
| Quesniaux VF et al. | The novel immunosuppressant FTY720 induces peripheral lymphodepletion of both T- and B-cells in cynomolgus monkeys when given alone, with Cyclosporine Neoral or with RAD. | 2000 | Transpl. Immunol. | pmid:11147698 |
| Chen Y et al. | The protective effect of ceramide in immature rat brain hypoxia-ischemia involves up-regulation of bcl-2 and reduction of TUNEL-positive cells. | 2001 | J. Cereb. Blood Flow Metab. | pmid:11149666 |
| Paik JH et al. | Sphingosine 1-phosphate-induced endothelial cell migration requires the expression of EDG-1 and EDG-3 receptors and Rho-dependent activation of alpha vbeta3- and beta1-containing integrins. | 2001 | J. Biol. Chem. | pmid:11150298 |
| Pyne S and Pyne N | Sphingosine 1-phosphate signalling via the endothelial differentiation gene family of G-protein-coupled receptors. | 2000 | Pharmacol. Ther. | pmid:11150592 |
| Han J and Shin I | Ceramide does not inhibit protein kinase C beta-dependent phospholipase D activity stimulated by anti-Fas monoclonal antibody in A20 cells. | 2000 | Cell. Signal. | pmid:11152958 |
| Conway A et al. | Ceramide-dependent regulation of p42/p44 mitogen-activated protein kinase and c-Jun N-terminal-directed protein kinase in cultured airway smooth muscle cells. | 2000 | Cell. Signal. | pmid:11152959 |
| Marash M and Gerst JE | t-SNARE dephosphorylation promotes SNARE assembly and exocytosis in yeast. | 2001 | EMBO J. | pmid:11157748 |
| Wu G et al. | Mutant NG108-15 cells (NG-CR72) deficient in GM1 synthase respond aberrantly to axonogenic stimuli and are vulnerable to calcium-induced apoptosis: they are rescued with LIGA-20. | 2001 | J. Neurochem. | pmid:11158239 |
| Sée V et al. | C2-ceramide and reactive oxygen species inhibit pituitary adenylate cyclase activating polypeptide (PACAP)-induced cyclic-AMP-dependent signalling pathway. | 2001 | J. Neurochem. | pmid:11158249 |
| Zinda MJ et al. | Ceramide induces the dephosphorylation and inhibition of constitutively activated Akt in PTEN negative U87mg cells. | 2001 | Biochem. Biophys. Res. Commun. | pmid:11162641 |
| Yang JH and Kodavanti PR | Possible molecular targets of halogenated aromatic hydrocarbons in neuronal cells. | 2001 | Biochem. Biophys. Res. Commun. | pmid:11162682 |
| Young KW and Nahorski SR | Intracellular sphingosine 1-phosphate production: a novel pathway for Ca2+ release. | 2001 | Semin. Cell Dev. Biol. | pmid:11162743 |
| Ardail D et al. | Occurrence of ceramides and neutral glycolipids with unusual long-chain base composition in purified rat liver mitochondria. | 2001 | FEBS Lett. | pmid:11163764 |
| Radin NS | Killing cancer cells by poly-drug elevation of ceramide levels: a hypothesis whose time has come? | 2001 | Eur. J. Biochem. | pmid:11168352 |
| Menné C et al. | T-cell receptor downregulation by ceramide-induced caspase activation and cleavage of the zeta chain. | 2001 | Scand. J. Immunol. | pmid:11169222 |
| Lev M and Milford AF | Sensitivity of a Bacteroides melaninogenicus strain to monosaccharides: effect on enzyme induction. | 1975 | J. Bacteriol. | pmid:1116985 |
| Stratford S et al. | Ceramide dissociates 3'-phosphoinositide production from pleckstrin homology domain translocation. | 2001 | Biochem. J. | pmid:11171115 |
| Tamura K et al. | Cloning and characterization of a cDNA encoding serine palmitoyltransferase in Arabidopsis thaliana. | 2000 | Biochem. Soc. Trans. | pmid:11171191 |
| Hatini V and DiNardo S | Distinct signals generate repeating striped pattern in the embryonic parasegment. | 2001 | Mol. Cell | pmid:11172720 |
| Chen CC et al. | Tumor necrosis factor-alpha-induced cyclooxygenase-2 expression via sequential activation of ceramide-dependent mitogen-activated protein kinases, and IkappaB kinase 1/2 in human alveolar epithelial cells. | 2001 | Mol. Pharmacol. | pmid:11179444 |
| Sonoda Y et al. | FTY720, a novel immunosuppressive agent, induces apoptosis in human glioma cells. | 2001 | Biochem. Biophys. Res. Commun. | pmid:11181042 |
| Kim DK et al. | NF-kappa B mediates the adaptation of human U937 cells to hydrogen peroxide. | 2001 | Free Radic. Biol. Med. | pmid:11182527 |
| Kim JH et al. | Sphingosine 1-phosphate activates Erk-1/-2 by transactivating epidermal growth factor receptor in rat-2 cells. | 2000 | IUBMB Life | pmid:11185956 |
| Shimada T et al. | Hepatocyte growth factor protects gastric epithelial cells against ceramide-induced apoptosis through induction of cyclooxygenase-2. | 2000 | Life Sci. | pmid:11197751 |
| Li XK et al. | Induction of lymphocyte apoptosis in rat liver allograft with ongoing rejection by FTY720. | 2001 | Clin. Exp. Immunol. | pmid:11207666 |
| van Mourik ID and Kelly DA | Immunosuppressive drugs in paediatric liver transplantation. | 2001 | Paediatr Drugs | pmid:11220404 |
| Selzner M et al. | Induction of apoptotic cell death and prevention of tumor growth by ceramide analogues in metastatic human colon cancer. | 2001 | Cancer Res. | pmid:11221856 |
| van der Westhuizen L et al. | The effect of repeated gavage doses of fumonisin B1 on the sphinganine and sphingosine levels in vervet monkeys. | 2001 | Toxicon | pmid:11223085 |
| Pohanka E | New immunosuppressive drugs: an update. | 2001 | Curr Opin Urol | pmid:11224744 |
| Hobson JP et al. | Role of the sphingosine-1-phosphate receptor EDG-1 in PDGF-induced cell motility. | 2001 | Science | pmid:11230698 |
| Jennemann R et al. | Glycoinositolphosphosphingolipids (basidiolipids) of higher mushrooms. | 2001 | Eur. J. Biochem. | pmid:11231270 |
| Senchenkov A et al. | Targeting ceramide metabolism--a strategy for overcoming drug resistance. | 2001 | J. Natl. Cancer Inst. | pmid:11238696 |
| Edsall LC et al. | Sphingosine kinase expression regulates apoptosis and caspase activation in PC12 cells. | 2001 | J. Neurochem. | pmid:11238741 |
| Kajimoto T et al. | Subtype-specific translocation of the delta subtype of protein kinase C and its activation by tyrosine phosphorylation induced by ceramide in HeLa cells. | 2001 | Mol. Cell. Biol. | pmid:11238914 |
| Breimer ME et al. | Presence of phytosphingosine combined with 2-hydroxy fatty acids in sphingomyelins of bovine kidney and intestinal mucosa. | 1975 | Lipids | pmid:1123973 |
| Venkataraman K and Futerman AH | Comparison of the metabolism of L-erythro- and L-threo-sphinganines and ceramides in cultured cells and in subcellular fractions. | 2001 | Biochim. Biophys. Acta | pmid:11239824 |
| Meyer zu Heringdorf D et al. | Stimulation of intracellular sphingosine-1-phosphate production by G-protein-coupled sphingosine-1-phosphate receptors. | 2001 | Eur. J. Pharmacol. | pmid:11239914 |
| Hollander MC et al. | Activation of Gadd34 by diverse apoptotic signals and suppression of its growth inhibitory effects by apoptotic inhibitors. | 2001 | Int. J. Cancer | pmid:11241327 |
| Mathur S et al. | Fumonisin B(1) increases serum sphinganine concentration but does not alter serum sphingosine concentration or induce cardiovascular changes in milk-fed calves. | 2001 | Toxicol. Sci. | pmid:11248151 |
| Mathur S et al. | Fumonisin B(1) is hepatotoxic and nephrotoxic in milk-fed calves. | 2001 | Toxicol. Sci. | pmid:11248152 |
| Hoshi M and Nagai Y | Novel sialosphingolipids from spermatozoa of the sea urchin Anthocidaris crassispina. | 1975 | Biochim. Biophys. Acta | pmid:1125301 |
| Liliom K et al. | Sphingosylphosphocholine is a naturally occurring lipid mediator in blood plasma: a possible role in regulating cardiac function via sphingolipid receptors. | 2001 | Biochem. J. | pmid:11256963 |
| Blaukat A and Dikic I | Activation of sphingosine kinase by the bradykinin B2 receptor and its implication in regulation of the ERK/MAP kinase pathway. | 2001 | Biol. Chem. | pmid:11258664 |
| Zou ZM et al. | Sphingosine derivatives from the seeds of Allium tuberosum. | 1999 | J Asian Nat Prod Res | pmid:11261207 |
| Carlson DB et al. | Fumonisin B1 promotes aflatoxin B1 and N-methyl-N'-nitro-nitrosoguanidine-initiated liver tumors in rainbow trout. | 2001 | Toxicol. Appl. Pharmacol. | pmid:11264020 |
| Prinetti A et al. | Changes in the lipid turnover, composition, and organization, as sphingolipid-enriched membrane domains, in rat cerebellar granule cells developing in vitro. | 2001 | J. Biol. Chem. | pmid:11264283 |
| Brinkmann V et al. | FTY720 alters lymphocyte homing and protects allografts without inducing general immunosuppression. | Transplant. Proc. | pmid:11266942 | |
| Chueh SC et al. | FTY720 prevents chronic rejection of rat heterotopic cardiac allografts. | Transplant. Proc. | pmid:11266948 | |
| Fu F et al. | FTY720, a novel immunosuppressive agent with insulinotropic activity, prolongs graft survival in a mouse islet transplantation model. | Transplant. Proc. | pmid:11267010 | |
| Troncoso P et al. | FTY 720 prevents ischemic reperfusion damage in rat kidneys. | Transplant. Proc. | pmid:11267102 | |
| Hajduch E et al. | Ceramide impairs the insulin-dependent membrane recruitment of protein kinase B leading to a loss in downstream signalling in L6 skeletal muscle cells. | 2001 | Diabetologia | pmid:11270673 |
| Thurman RG et al. | SPC-100270, a protein kinase C inhibitor, reduced hypoxic injury due to reperfusion following orthotopic liver transplantation in the rat. | 1994 | Transpl. Int. | pmid:11271195 |
| Alderton F et al. | G-protein-coupled receptor stimulation of the p42/p44 mitogen-activated protein kinase pathway is attenuated by lipid phosphate phosphatases 1, 1a, and 2 in human embryonic kidney 293 cells. | 2001 | J. Biol. Chem. | pmid:11278307 |
| Igarashi J et al. | Sphingosine 1-phosphate and activation of endothelial nitric-oxide synthase. differential regulation of Akt and MAP kinase pathways by EDG and bradykinin receptors in vascular endothelial cells. | 2001 | J. Biol. Chem. | pmid:11278407 |
| El Bawab S et al. | Biochemical characterization of the reverse activity of rat brain ceramidase. A CoA-independent and fumonisin B1-insensitive ceramide synthase. | 2001 | J. Biol. Chem. | pmid:11278489 |
| Morales-Ruiz M et al. | Sphingosine 1-phosphate activates Akt, nitric oxide production, and chemotaxis through a Gi protein/phosphoinositide 3-kinase pathway in endothelial cells. | 2001 | J. Biol. Chem. | pmid:11278592 |
| Birchwood CJ et al. | Calcium influx and signaling in yeast stimulated by intracellular sphingosine 1-phosphate accumulation. | 2001 | J. Biol. Chem. | pmid:11278643 |
| Riboni L et al. | Basic fibroblast growth factor-induced proliferation of primary astrocytes. evidence for the involvement of sphingomyelin biosynthesis. | 2001 | J. Biol. Chem. | pmid:11278937 |
| Ng CK et al. | Drought-induced guard cell signal transduction involves sphingosine-1-phosphate. | 2001 | Nature | pmid:11279499 |
| Frago LM et al. | Short-chain ceramide regulates hepatic methionine adenosyltransferase expression. | 2001 | J. Hepatol. | pmid:11281546 |
| Ohlsson J and Magnusson G | A short and practical route to 3-O-benzoyl azidosphingosine. | 2001 | Carbohydr. Res. | pmid:11284510 |
| Furuya K et al. | Cell permeable exogenous ceramide reduces infarct size in spontaneously hypertensive rats supporting in vitro studies that have implicated ceramide in induction of tolerance to ischemia. | 2001 | J. Cereb. Blood Flow Metab. | pmid:11295877 |
| Sperling P et al. | Functional characterization of sphingolipid C4-hydroxylase genes from Arabidopsis thaliana. | 2001 | FEBS Lett. | pmid:11297741 |
| Andor A et al. | YopE of Yersinia, a GAP for Rho GTPases, selectively modulates Rac-dependent actin structures in endothelial cells. | 2001 | Cell. Microbiol. | pmid:11298653 |
| Lai TS et al. | Calcium regulates S-nitrosylation, denitrosylation, and activity of tissue transglutaminase. | 2001 | Biochemistry | pmid:11305905 |
| Kim DS et al. | Ceramide inhibits cell proliferation through Akt/PKB inactivation and decreases melanin synthesis in Mel-Ab cells. | 2001 | Pigment Cell Res. | pmid:11310790 |
| van der Westhuizen L et al. | The effect of a single gavage dose of fumonisin B(2) on the sphinganine and sphingosine concentrations in vervet monkeys. | 2001 | Food Chem. Toxicol. | pmid:11313111 |
| Solfrizzo M et al. | Ineffectiveness of activated carbon in reducing the alteration of sphingolipid metabolism in rats exposed to fumonisin-contaminated diets. | 2001 | Food Chem. Toxicol. | pmid:11313118 |
| Hsu YW et al. | Ceramide inhibits lipopolysaccharide-mediated nitric oxide synthase and cyclooxygenase-2 induction in macrophages: effects on protein kinases and transcription factors. | 2001 | J. Immunol. | pmid:11313375 |
| Kranenburg O and Moolenaar WH | Ras-MAP kinase signaling by lysophosphatidic acid and other G protein-coupled receptor agonists. | 2001 | Oncogene | pmid:11313900 |
| Nikolova Z et al. | Combined FTY720/cyclosporine A treatment promotes graft survival and lowers the peripheral lymphocyte count in DA to lewis heart and skin transplantation models. | 2001 | Transpl. Immunol. | pmid:11316070 |
| Yatomi Y et al. | Sphingosine 1-phosphate: synthesis and release. | 2001 | Prostaglandins Other Lipid Mediat. | pmid:11324700 |
| Goetzl EJ | Pleiotypic mechanisms of cellular responses to biologically active lysophospholipids. | 2001 | Prostaglandins Other Lipid Mediat. | pmid:11324701 |
| Olivera A and Spiegel S | Sphingosine kinase: a mediator of vital cellular functions. | 2001 | Prostaglandins Other Lipid Mediat. | pmid:11324702 |
| Hla T | Sphingosine 1-phosphate receptors. | 2001 | Prostaglandins Other Lipid Mediat. | pmid:11324703 |
| Mandala SM | Sphingosine-1-phosphate phosphatases. | 2001 | Prostaglandins Other Lipid Mediat. | pmid:11324704 |
| Lynch KR and Macdonald TL | Structure activity relationships of lysophospholipid mediators. | 2001 | Prostaglandins Other Lipid Mediat. | pmid:11324706 |
| Panetti TS et al. | Modulation of cell interactions with extracellular matrix by lysophosphatidic acid and sphingosine 1-phosphate. | 2001 | Prostaglandins Other Lipid Mediat. | pmid:11324710 |
| Zhang DX et al. | Ceramide reduces endothelium-dependent vasodilation by increasing superoxide production in small bovine coronary arteries. | 2001 | Circ. Res. | pmid:11325875 |
sphingosine
sphingosine is a lipid of Sphingolipids (SP) class.
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