| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Kobayashi N et al. | Fluorescence-based rapid measurement of sphingosine-1-phosphate transport activity in erythrocytes. | 2016 | J. Lipid Res. | pmid:27655910 |
| Evangelisti C et al. | Therapeutic potential of targeting sphingosine kinases and sphingosine 1-phosphate in hematological malignancies. | 2016 | Leukemia | pmid:27461062 |
| Kemppainen K et al. | Sphingosylphosphorylcholine regulates the Hippo signaling pathway in a dual manner. | 2016 | Cell. Signal. | pmid:27634386 |
| Custódio R et al. | Characterization of secreted sphingosine-1-phosphate lyases required for virulence and intracellular survival of Burkholderia pseudomallei. | 2016 | Mol. Microbiol. | pmid:27632710 |
| Ebenezer DL et al. | Targeting sphingosine-1-phosphate signaling in lung diseases. | 2016 | Pharmacol. Ther. | pmid:27621206 |
| Tsuchida J et al. | Breast cancer sphingosine-1-phosphate is associated with phospho-sphingosine kinase 1 and lymphatic metastasis. | 2016 | J. Surg. Res. | pmid:27621003 |
| Nagahashi M et al. | The roles of bile acids and sphingosine-1-phosphate signaling in the hepatobiliary diseases. | 2016 | J. Lipid Res. | pmid:27459945 |
| Poissonnier A et al. | CD95-Mediated Calcium Signaling Promotes T Helper 17 Trafficking to Inflamed Organs in Lupus-Prone Mice. | 2016 | Immunity | pmid:27438772 |
| Zhang Q et al. | Berberine Preconditioning Protects Neurons Against Ischemia via Sphingosine-1-Phosphate and Hypoxia-Inducible Factor-1[Formula: see text]. | 2016 | Am. J. Chin. Med. | pmid:27430910 |
| Adamiak M et al. | Downregulation of Heme Oxygenase 1 (HO-1) Activity in Hematopoietic Cells Enhances Their Engraftment After Transplantation. | 2016 | Cell Transplant | pmid:27412411 |
| Bao XH et al. | [Role and related mechanism of S1P/S1P1 signal pathway during post conditioning of hypertrophic cardiomyocytes]. | 2016 | Zhonghua Xin Xue Guan Bing Za Zhi | pmid:27220580 |
| Marfia G et al. | The Adipose Mesenchymal Stem Cell Secretome Inhibits Inflammatory Responses of Microglia: Evidence for an Involvement of Sphingosine-1-Phosphate Signalling. | 2016 | Stem Cells Dev. | pmid:27217090 |
| Versmissen J et al. | Familial hypercholesterolaemia: cholesterol efflux and coronary disease. | 2016 | Eur. J. Clin. Invest. | pmid:27208892 |
| Sauvé M et al. | Tumor Necrosis Factor/Sphingosine-1-Phosphate Signaling Augments Resistance Artery Myogenic Tone in Diabetes. | 2016 | Diabetes | pmid:27207546 |
| Zhang XE et al. | Activation of RhoA, but Not Rac1, Mediates Early Stages of S1P-Induced Endothelial Barrier Enhancement. | 2016 | PLoS ONE | pmid:27187066 |
| Fleming JK et al. | A novel approach for measuring sphingosine-1-phosphate and lysophosphatidic acid binding to carrier proteins using monoclonal antibodies and the Kinetic Exclusion Assay. | 2016 | J. Lipid Res. | pmid:27444045 |
| Lv M et al. | Sphingosine kinase 1/sphingosine-1-phosphate regulates the expression of interleukin-17A in activated microglia in cerebral ischemia/reperfusion. | 2016 | Inflamm. Res. | pmid:27002656 |
| Frej C et al. | Sphingosine 1-phosphate and its carrier apolipoprotein M in human sepsis and in Escherichia coli sepsis in baboons. | 2016 | J. Cell. Mol. Med. | pmid:26990127 |
| Gao H et al. | Bacillus cereus strain S2 shows high nematicidal activity against Meloidogyne incognita by producing sphingosine. | 2016 | Sci Rep | pmid:27338781 |
| Zhang M et al. | Critical Role of COI1-Dependent Jasmonate Pathway in AAL toxin induced PCD in Tomato Revealed by Comparative Proteomics. | 2016 | Sci Rep | pmid:27324416 |
| Tang X et al. | Tetracyclines increase lipid phosphate phosphatase expression on plasma membranes and turnover of plasma lysophosphatidate. | 2016 | J. Lipid Res. | pmid:26884614 |
| Uranbileg B et al. | Increased mRNA Levels of Sphingosine Kinases and S1P Lyase and Reduced Levels of S1P Were Observed in Hepatocellular Carcinoma in Association with Poorer Differentiation and Earlier Recurrence. | 2016 | PLoS ONE | pmid:26886371 |
| Chumanevich A et al. | Sphingosine-1-Phosphate/Sphingosine-1-Phosphate Receptor 2 Axis Can Promote Mouse and Human Primary Mast Cell Angiogenic Potential through Upregulation of Vascular Endothelial Growth Factor-A and Matrix Metalloproteinase-2. | 2016 | Mediators Inflamm. | pmid:26884643 |
| Ko P et al. | Extracellular Matrix Rigidity-dependent Sphingosine-1-phosphate Secretion Regulates Metastatic Cancer Cell Invasion and Adhesion. | 2016 | Sci Rep | pmid:26877098 |
| Pastor-Flores D et al. | Lipid regulators of Pkh2 in Candida albicans, the protein kinase ortholog of mammalian PDK1. | 2016 | Biochim. Biophys. Acta | pmid:26743850 |
| Abu Khweek A et al. | The Sphingosine-1-Phosphate Lyase (LegS2) Contributes to the Restriction of Legionella pneumophila in Murine Macrophages. | 2016 | PLoS ONE | pmid:26741365 |
| Deniz U et al. | A systematic methodology for large scale compound screening: A case study on the discovery of novel S1PL inhibitors. | 2016 | J. Mol. Graph. Model. | pmid:26724452 |
| Rana A and Sharma S | Mechanism of sphingosine-1-phosphate induced cardioprotection against I/R injury in diabetic rat heart: Possible involvement of glycogen synthase kinase 3β and mitochondrial permeability transition pore. | 2016 | Clin. Exp. Pharmacol. Physiol. | pmid:26582369 |
| Yuasa D et al. | C1q/TNF-related protein-1 functions to protect against acute ischemic injury in the heart. | 2016 | FASEB J. | pmid:26578687 |
| Priyadarsini S et al. | Complete metabolome and lipidome analysis reveals novel biomarkers in the human diabetic corneal stroma. | 2016 | Exp. Eye Res. | pmid:27742548 |
| Simula S et al. | Modulation of sphingosine receptors influences circadian pattern of cardiac autonomic regulation. | 2016 | Physiol Rep | pmid:27624686 |
| Mikami D et al. | Effects of Asterias amurensis-derived Sphingoid Bases on the de novo Ceramide Synthesis in Cultured Normal Human Epidermal Keratinocytes. | 2016 | J Oleo Sci | pmid:27430385 |
| Rice TC et al. | Frontline Science: Sphingosine rescues burn-injured mice from pulmonary Pseudomonas aeruginosa infection. | 2016 | J. Leukoc. Biol. | pmid:27418352 |
| Nagahashi M et al. | Interstitial Fluid Sphingosine-1-Phosphate in Murine Mammary Gland and Cancer and Human Breast Tissue and Cancer Determined by Novel Methods. | 2016 | J Mammary Gland Biol Neoplasia | pmid:27194029 |
| Nigro E et al. | Role of adiponectin in sphingosine-1-phosphate induced airway hyperresponsiveness and inflammation. | 2016 | Pharmacol. Res. | pmid:26462929 |
| Sonnenberger S et al. | Synthesis of ceramides NS and NP with perdeuterated and specifically ω deuterated N-acyl residues. | 2016 | J Labelled Comp Radiopharm | pmid:27634543 |
| Serdar M et al. | Fingolimod protects against neonatal white matter damage and long-term cognitive deficits caused by hyperoxia. | 2016 | Brain Behav. Immun. | pmid:26456693 |
| Cheng JC et al. | Sphingosine-1-phosphate induces COX-2 expression and PGE2 production in human granulosa cells through a S1P1/3-mediated YAP signaling. | 2016 | Cell. Signal. | pmid:26994820 |
| Arish M et al. | Sphingosine-1-phosphate signaling: unraveling its role as a drug target against infectious diseases. | 2016 | Drug Discov. Today | pmid:26456576 |
| Masching S et al. | Gastrointestinal Degradation of Fumonisin Bâ‚ by Carboxylesterase FumD Prevents Fumonisin Induced Alteration of Sphingolipid Metabolism in Turkey and Swine. | 2016 | Toxins (Basel) | pmid:27007395 |
| Güntert T et al. | 1-Deoxysphingolipid-induced neurotoxicity involves N-methyl-d-aspartate receptor signaling. | 2016 | Neuropharmacology | pmid:27016021 |
| Zhang L et al. | Sphingosine-1-phosphate Maintains Normal Vascular Permeability by Preserving Endothelial Surface Glycocalyx in Intact Microvessels. | 2016 | Microcirculation | pmid:27015105 |
| Bae SJ et al. | The circulating sphingosine-1-phosphate level predicts incident fracture in postmenopausal women: a 3.5-year follow-up observation study. | 2016 | Osteoporos Int | pmid:26984570 |
| Kolb JP and Martinez J | Bon EPOtit! S1P-Mediated EPO Signaling Whets a Macrophage's Appetite for Apoptotic Cells. | 2016 | Immunity | pmid:26885850 |
| Martinková M and Gonda J | Marine cytotoxic jaspine B and its stereoisomers: biological activity and syntheses. | 2016 | Carbohydr. Res. | pmid:26878486 |
| Kurano M et al. | Resveratrol exerts a biphasic effect on apolipoprotein M. | 2016 | Br. J. Pharmacol. | pmid:26445217 |
| Lv H et al. | Preclinical Evaluation of Liposomal C8 Ceramide as a Potent anti-Hepatocellular Carcinoma Agent. | 2016 | PLoS ONE | pmid:26727592 |
| Loru D et al. | Intramolecular interactions in the polar headgroup of sphingosine: serinol. | 2016 | Chem. Commun. (Camb.) | pmid:26727395 |
| Melnik BC | Rosacea: The Blessing of the Celts - An Approach to Pathogenesis Through Translational Research. | 2016 | Acta Derm. Venereol. | pmid:26304030 |
| MartÃnez-Montañés F et al. | Accumulation of long-chain bases in yeast promotes their conversion to a long-chain base vinyl ether. | 2016 | J. Lipid Res. | pmid:27561298 |
| Kim BJ et al. | The effect of sphingosine-1-phosphate on bone metabolism in humans depends on its plasma/bone marrow gradient. | 2016 | J. Endocrinol. Invest. | pmid:26219613 |
| Lee EJ et al. | Epithelial membrane protein 2 regulates sphingosylphosphorylcholine-induced keratin 8 phosphorylation and reorganization: Changes of PP2A expression by interaction with alpha4 and caveolin-1 in lung cancer cells. | 2016 | Biochim. Biophys. Acta | pmid:26876307 |
| Stone ML et al. | Sphingosine-1-phosphate receptor 1 agonism attenuates lung ischemia-reperfusion injury. | 2015 | Am. J. Physiol. Lung Cell Mol. Physiol. | pmid:25910934 |
| Klein CJ | Solving the riddle of the sphinx may provide new insights into diabetes and polyneuropathy. | 2015 | Diabetes | pmid:25713196 |
| Rosini JM et al. | Delayed cardiac dysrhythmias after fingolimod administration. | 2015 | Am J Emerg Med | pmid:25669873 |
| Sellebjerg F and Sørensen PS | Therapeutic interference with leukocyte recirculation in multiple sclerosis. | 2015 | Eur. J. Neurol. | pmid:25582213 |
| Carreira AC et al. | Tackling the biophysical properties of sphingolipids to decipher their biological roles. | 2015 | Biol. Chem. | pmid:25581755 |
| Nussbaum C et al. | Sphingosine-1-phosphate receptor 3 promotes leukocyte rolling by mobilizing endothelial P-selectin. | 2015 | Nat Commun | pmid:25832730 |
| Martin TJ and Sims NA | Calcitonin physiology, saved by a lysophospholipid. | 2015 | J. Bone Miner. Res. | pmid:25581311 |
| Riley RT et al. | A blood spot method for detecting fumonisin-induced changes in putative sphingolipid biomarkers in LM/Bc mice and humans. | 2015 | Food Addit Contam Part A Chem Anal Control Expo Risk Assess | pmid:25833119 |
| Airas L et al. | In vivo PET imaging demonstrates diminished microglial activation after fingolimod treatment in an animal model of multiple sclerosis. | 2015 | J. Nucl. Med. | pmid:25572093 |
| Proia RL and Hla T | Emerging biology of sphingosine-1-phosphate: its role in pathogenesis and therapy. | 2015 | J. Clin. Invest. | pmid:25831442 |
| Wehinger S et al. | Phosphorylation of caveolin-1 on tyrosine-14 induced by ROS enhances palmitate-induced death of beta-pancreatic cells. | 2015 | Biochim. Biophys. Acta | pmid:25572853 |
| Rhee SH et al. | Pelvic organ prolapse is associated with alteration of sphingosine-1-phosphate/Rho-kinase signalling pathway in human vaginal wall. | 2015 | J Obstet Gynaecol | pmid:25692679 |
| Tay KH et al. | Involvement of vacuolar H(+)-ATPase in killing of human melanoma cells by the sphingosine kinase analogue FTY720. | 2015 | Pigment Cell Melanoma Res | pmid:25358761 |
| Ji F et al. | K6PC-5, a novel sphingosine kinase 1 (SphK1) activator, alleviates dexamethasone-induced damages to osteoblasts through activating SphK1-Akt signaling. | 2015 | Biochem. Biophys. Res. Commun. | pmid:25680461 |
| Holmes D | Bone: Key role for S1P in bone remodelling. | 2015 | Nat Rev Endocrinol | pmid:25350065 |
| Roviezzo F et al. | S1P-induced airway smooth muscle hyperresponsiveness and lung inflammation in vivo: molecular and cellular mechanisms. | 2015 | Br. J. Pharmacol. | pmid:25439580 |
| Hashimoto Y et al. | Sphingosine-1-phosphate inhibits differentiation of C3H10T1/2 cells into adipocyte. | 2015 | Mol. Cell. Biochem. | pmid:25445169 |
| Carroll B et al. | Sphingolipids in the DNA damage response. | 2015 | Adv Biol Regul | pmid:25434743 |
| Xiu L et al. | Intracellular sphingosine 1-phosphate contributes to collagen expression of hepatic myofibroblasts in human liver fibrosis independent of its receptors. | 2015 | Am. J. Pathol. | pmid:25432063 |
| Moon MH et al. | Activation of S1P2 receptor, a possible mechanism of inhibition of adipogenic differentiation by sphingosine 1‑phosphate. | 2015 | Mol Med Rep | pmid:25351259 |
| Zhu Z et al. | Extracellular α-crystallin protects astrocytes from cell death through activation of MAPK, PI3K/Akt signaling pathway and blockade of ROS release from mitochondria. | 2015 | Brain Res. | pmid:25998538 |
| Gómez-Torres MJ et al. | Metabolites involved in cellular communication among human cumulus-oocyte-complex and sperm during in vitro fertilization. | 2015 | Reprod. Biol. Endocrinol. | pmid:26553294 |
| Fogarty CE and Bergmann A | The Sound of Silence: Signaling by Apoptotic Cells. | 2015 | Curr. Top. Dev. Biol. | pmid:26431570 |
| Tang H et al. | Expression of Sphingosine-1-phosphate (S1P) on the cerebral vasospasm after subarachnoid hemorrhage in rabbits. | 2015 | Acta Cir Bras | pmid:26560422 |
| Zhao C et al. | Chemical Hypoxia Brings to Light Altered Autocrine Sphingosine-1-Phosphate Signalling in Rheumatoid Arthritis Synovial Fibroblasts. | 2015 | Mediators Inflamm. | pmid:26556954 |
| Deng Z et al. | Enterobacteria-secreted particles induce production of exosome-like S1P-containing particles by intestinal epithelium to drive Th17-mediated tumorigenesis. | 2015 | Nat Commun | pmid:25907800 |
| Tanaka K et al. | Hypoxia remodels the composition of the constituent ceramide species of HexCer and Hex2Cer with phytosphingosine and hydroxy fatty acids in human colon cancer LS174T cells. | 2015 | Glycoconj. J. | pmid:26194060 |
| Megson ZA et al. | Inositol-phosphodihydroceramides in the periodontal pathogen Tannerella forsythia: Structural analysis and incorporation of exogenous myo-inositol. | 2015 | Biochim. Biophys. Acta | pmid:26277409 |
| Hoffmann FS et al. | Fingolimod induces neuroprotective factors in human astrocytes. | 2015 | J Neuroinflammation | pmid:26419927 |
| Poulsen C et al. | Differential cytotoxicity of long-chain bases for human oral gingival epithelial keratinocytes, oral fibroblasts, and dendritic cells. | 2015 | Toxicol. Lett. | pmid:26005054 |
| Wang W and Fromm M | Sphingolipids are required for efficient triacylglycerol loss in conjugated linoleic Acid treated adipocytes. | 2015 | PLoS ONE | pmid:25906159 |
| Boczkowska-Radziwon B et al. | Ozonation of human blood increases sphingosine-1-phosphate in plasma. | 2015 | J. Physiol. Pharmacol. | pmid:25903957 |
| Cheng Y et al. | Actin polymerization-enhancing drugs promote ovarian follicle growth mediated by the Hippo signaling effector YAP. | 2015 | FASEB J. | pmid:25690654 |
| Cantalupo A et al. | Nogo-B regulates endothelial sphingolipid homeostasis to control vascular function and blood pressure. | 2015 | Nat. Med. | pmid:26301690 |
| Adamiak M et al. | Evidence for the involvement of sphingosine-1-phosphate in the homing and engraftment of hematopoietic stem cells to bone marrow. | 2015 | Oncotarget | pmid:26299919 |
| Mori H et al. | Smad3 deficiency leads to mandibular condyle degradation via the sphingosine 1-phosphate (S1P)/S1P3 signaling axis. | 2015 | Am. J. Pathol. | pmid:26272361 |
| Badimon JJ and Santos-Gallego CG | HDL Dysfunction: Is the Answer in the Sphinx's Riddle? | 2015 | J. Am. Coll. Cardiol. | pmid:26403345 |
| Airola MV et al. | Structural Basis for Ceramide Recognition and Hydrolysis by Human Neutral Ceramidase. | 2015 | Structure | pmid:26190575 |
| Vettorazzi S et al. | Glucocorticoids limit acute lung inflammation in concert with inflammatory stimuli by induction of SphK1. | 2015 | Nat Commun | pmid:26183376 |
| Michels M et al. | Decreased plasma levels of the endothelial protective sphingosine-1-phosphate are associated with dengue-induced plasma leakage. | 2015 | J. Infect. | pmid:26183296 |
| Kappos L et al. | Switching from natalizumab to fingolimod: A randomized, placebo-controlled study in RRMS. | 2015 | Neurology | pmid:26024899 |
| Stüve O and Bourdette D | Natalizumab to fingolimod: Questions answered, unanswered, and unasked. | 2015 | Neurology | pmid:26024898 |
| Durham JT et al. | Pericyte chemomechanics and the angiogenic switch: insights into the pathogenesis of proliferative diabetic retinopathy? | 2015 | Invest. Ophthalmol. Vis. Sci. | pmid:26030100 |
| Książek M et al. | Sources, metabolism, and regulation of circulating sphingosine-1-phosphate. | 2015 | J. Lipid Res. | pmid:26014962 |
| Hyder CL et al. | Sphingolipids inhibit vimentin-dependent cell migration. | 2015 | J. Cell. Sci. | pmid:25908861 |
| Fujiwara M et al. | Cbl-b-deficient mice express alterations in trafficking-related molecules but retain sensitivity to the multiple sclerosis therapeutic agent, FTY720. | 2015 | Clin. Immunol. | pmid:25829233 |
| Shaikh RS et al. | Synthesis and evaluation of fluorinated fingolimod (FTY720) analogues for sphingosine-1-phosphate receptor molecular imaging by positron emission tomography. | 2015 | J. Med. Chem. | pmid:25826109 |
| Camaré C et al. | Oxidized LDL-induced angiogenesis involves sphingosine 1-phosphate: prevention by anti-S1P antibody. | 2015 | Br. J. Pharmacol. | pmid:25176316 |
sphingosine
sphingosine is a lipid of Sphingolipids (SP) class.
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