sphingosine

sphingosine is a lipid of Sphingolipids (SP) class.

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There are no associated biomedical information in the current reference collection.

Current reference collection contains 26061 references associated with sphingosine in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

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Authors Title Published Journal PubMed Link
Contaifer D et al. Unsupervised analysis of combined lipid and coagulation data reveals coagulopathy subtypes among dialysis patients. 2017 J. Lipid Res. pmid:27993949
Łukomska A et al. The effect of low levels of lead (Pb) in the blood on levels of sphingosine-1-phosphate (S1P) and expression of S1P receptor 1 in the brain of the rat in the perinatal period. 2017 Chemosphere pmid:27697711
Khodorova A et al. The TrkA receptor mediates experimental thermal hyperalgesia produced by nerve growth factor: Modulation by the p75 neurotrophin receptor. 2017 Neuroscience pmid:27826102
Takahashi C et al. Vehicle-dependent Effects of Sphingosine 1-phosphate on Plasminogen Activator Inhibitor-1 Expression. 2017 J. Atheroscler. Thromb. pmid:28321011
Kitamura T et al. Phytosphingosine degradation pathway includes fatty acid α-oxidation reactions in the endoplasmic reticulum. 2017 Proc. Natl. Acad. Sci. U.S.A. pmid:28289220
Reinhard NR et al. The balance between Gα-Cdc42/Rac and Gα/-RhoA pathways determines endothelial barrier regulation by sphingosine-1-phosphate. 2017 Mol. Biol. Cell pmid:28954861
Azimzadeh K et al. Evaluation of plasma sphingosine 1-phosphate, hepcidin and cardiovascular damage biomarkers (cardiac troponin I and homocysteine) in rats infected with brucellosis and vaccinated (Rev-1, RB-51). 2017 Microb. Pathog. pmid:28533142
Dany M Sphingosine metabolism as a therapeutic target in cutaneous melanoma. 2017 Transl Res pmid:28528915
Janecke AR et al. Deficiency of the sphingosine-1-phosphate lyase SGPL1 is associated with congenital nephrotic syndrome and congenital adrenal calcifications. 2017 Hum. Mutat. pmid:28181337
Qi H et al. Analysis of sphingolipids in human corneal fibroblasts from normal and keratoconus patients. 2017 J. Lipid Res. pmid:28188148
Kulinski JM et al. Sphingosine-1-phosphate and other lipid mediators generated by mast cells as critical players in allergy and mast cell function. 2016 Eur. J. Pharmacol. pmid:25941085
Surya VN et al. Sphingosine 1-phosphate receptor 1 regulates the directional migration of lymphatic endothelial cells in response to fluid shear stress. 2016 J R Soc Interface pmid:27974574
Soltau I et al. Serum-Sphingosine-1-Phosphate Concentrations Are Inversely Associated with Atherosclerotic Diseases in Humans. 2016 PLoS ONE pmid:27973607
Al Alam N and Kreydiyyeh SI FTY720P inhibits hepatic Na(+)-K(+) ATPase via S1PR2 and PGE2. 2016 Biochem. Cell Biol. pmid:27501354
Morillon YM et al. Antibody Binding to CD4 Induces Rac GTPase Activation and Alters T Cell Migration. 2016 J. Immunol. pmid:27694496
Gstalder C et al. FTY720 (Fingolimod) Inhibits HIF1 and HIF2 Signaling, Promotes Vascular Remodeling, and Chemosensitizes in Renal Cell Carcinoma Animal Model. 2016 Mol. Cancer Ther. pmid:27507852
Hashimoto Y et al. Sphingosine-1-phosphate-enhanced Wnt5a promotes osteogenic differentiation in C3H10T1/2 cells. 2016 Cell Biol. Int. pmid:27486054
Wang Y et al. Acid sphingomyelinase mediates 50-Hz magnetic field-induced EGF receptor clustering on lipid raft. 2016 J. Recept. Signal Transduct. Res. pmid:26915736
Juif PE et al. Clinical pharmacology, efficacy, and safety aspects of sphingosine-1-phosphate receptor modulators. 2016 Expert Opin Drug Metab Toxicol pmid:27249325
Koresawa R et al. Sphingosine-1-phosphate receptor 1 as a prognostic biomarker and therapeutic target for patients with primary testicular diffuse large B-cell lymphoma. 2016 Br. J. Haematol. pmid:27061580
Resop RS et al. Sphingosine-1-phosphate/sphingosine-1-phosphate receptor 1 signaling is required for migration of naive human T cells from the thymus to the periphery. 2016 J. Allergy Clin. Immunol. pmid:27056271
Mi JN et al. New Immunosuppressive Sphingoid Base and Ceramide Analogues in Wild Cordyceps. 2016 Sci Rep pmid:27966660
Guo J et al. Identification and synthesis of potent and selective pyridyl-isoxazole based agonists of sphingosine-1-phosphate 1 (S1P1). 2016 Bioorg. Med. Chem. Lett. pmid:27055941
Trinh HK et al. Exploration of the Sphingolipid Metabolite, Sphingosine-1-phosphate and Sphingosine, as Novel Biomarkers for Aspirin-exacerbated Respiratory Disease. 2016 Sci Rep pmid:27830727
Puli MR et al. Stomatal closure induced by phytosphingosine-1-phosphate and sphingosine-1-phosphate depends on nitric oxide and pH of guard cells in Pisum sativum. 2016 Planta pmid:27233507
Park K et al. ER stress stimulates production of the key antimicrobial peptide, cathelicidin, by forming a previously unidentified intracellular S1P signaling complex. 2016 Proc. Natl. Acad. Sci. U.S.A. pmid:26903652
Olmo ED et al. Efficacious In Vitro and In Vivo Effects of Dihydrosphingosine-Ethambutol Analogues Against Susceptible and Multi-drug-resistant Mycobacterium tuberculosis. 2016 Arch. Med. Res. pmid:27664485
Arias SL et al. Toxin distribution and sphingoid base imbalances in Fusarium verticillioides-infected and fumonisin B1-watered maize seedlings. 2016 Phytochemistry pmid:26903312
Tran HB et al. Cigarette smoke inhibits efferocytosis via deregulation of sphingosine kinase signaling: reversal with exogenous S1P and the S1P analogue FTY720. 2016 J. Leukoc. Biol. pmid:26792820
Chapurlat RD and Confavreux CB Novel biological markers of bone: from bone metabolism to bone physiology. 2016 Rheumatology (Oxford) pmid:26790456
Zhang Y et al. Ceramide Production Mediates Aldosterone-Induced Human Umbilical Vein Endothelial Cell (HUVEC) Damages. 2016 PLoS ONE pmid:26788916
Dillmann C et al. S1PR4 Signaling Attenuates ILT 7 Internalization To Limit IFN-α Production by Human Plasmacytoid Dendritic Cells. 2016 J. Immunol. pmid:26783340
Chen J et al. Deletion of sphingosine kinase 1 ameliorates hepatic steatosis in diet-induced obese mice: Role of PPARγ. 2016 Biochim. Biophys. Acta pmid:26615875
Maczis M et al. Sphingosine-1-phosphate and estrogen signaling in breast cancer. 2016 Adv Biol Regul pmid:26601898
Tan SF et al. Acid ceramidase is upregulated in AML and represents a novel therapeutic target. 2016 Oncotarget pmid:27825124
Veltman M et al. Correction of lung inflammation in a F508del CFTR murine cystic fibrosis model by the sphingosine-1-phosphate lyase inhibitor LX2931. 2016 Am. J. Physiol. Lung Cell Mol. Physiol. pmid:27663991
Tölle M et al. Regulation of endothelial nitric oxide synthase activation in endothelial cells by S1P1 and S1P3. 2016 Biochem. Biophys. Res. Commun. pmid:27282481
Uemura M et al. Inhibitory Effect of Dihydrosphingosine with α-Tocopherol on Volatile Formation during the Autoxidation of Polyunsaturated Triacylglycerols. 2016 J Oleo Sci pmid:27477074
Liu B et al. Synthetic Studies on a Pachastrissamine Sulfur Analogue: Synthesis of a 4-epi-Sulfur Analogue. 2016 Chem. Pharm. Bull. pmid:27039834
Grammatikos G et al. Persistence of HCV in Acutely-Infected Patients Depletes C24-Ceramide and Upregulates Sphingosine and Sphinganine Serum Levels. 2016 Int J Mol Sci pmid:27304952
Gardner NM et al. Elevated nuclear sphingoid base-1-phosphates and decreased histone deacetylase activity after fumonisin B1 treatment in mouse embryonic fibroblasts. 2016 Toxicol. Appl. Pharmacol. pmid:26905748
Mezeiová E et al. Total synthesis and antiproliferative/cytotoxic profiling of 2-epi-jaspine B. 2016 Carbohydr. Res. pmid:26895543
Aksu F et al. Antioxidant and renoprotective effects of sphingosylphosphorylcholine on contrast-induced nephropathy in rats. 2016 Ren Fail pmid:27309733
Cohen MV et al. Cangrelor-Mediated Cardioprotection Requires Platelets and Sphingosine Phosphorylation. 2016 Cardiovasc Drugs Ther pmid:26780906
Fang J et al. N,N-dimethylsphingosine attenuates myocardial ischemia-reperfusion injury by recruiting regulatory T cells through PI3K/Akt pathway in mice. 2016 Basic Res. Cardiol. pmid:27048490
Reeves PM et al. Endocytosis of Ligand-Activated Sphingosine 1-Phosphate Receptor 1 Mediated by the Clathrin-Pathway. 2016 Traffic pmid:26481905
Tani K et al. Hair Cell Loss Induced by Sphingosine and a Sphingosine Kinase Inhibitor in the Rat Cochlea. 2016 Neurotox Res pmid:26472207
Racca V et al. Response to letter regarding article 'Fingolimod effects on left ventricular function in multiple sclerosis'. 2016 Mult. Scler. pmid:26359278
Bakshi R and Häring DA Comment on "Fingolimod effects on left ventricular function in multiple sclerosis" Mult Scler 2015. 2016 Mult. Scler. pmid:26359277
Touat-Hamici Z et al. Role of lipid phosphate phosphatase 3 in human aortic endothelial cell function. 2016 Cardiovasc. Res. pmid:27694435