| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Chiba K and Kataoka H | [Therapeutic effect of S1P receptor modifying drugs for autoimmune diseases]. | 2008 | Nippon Yakurigaku Zasshi | pmid:18421849 |
| Hirafuji M et al. | [Modulation of sphingosine 1-phosphate, a new lipid mediator, on nitric oxide production by vascular smooth muscle cells]. | 2002 | Nippon Yakurigaku Zasshi | pmid:12491784 |
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| Okajima F | [Establishment of the method for the measurement of sphingosine-1-phosphate in biological samples and its application for S1P research]. | 2001 | Nippon Yakurigaku Zasshi | pmid:11778456 |
| Wang X et al. | Diffusion tensor imaging detects treatment effects of FTY720 in experimental autoimmune encephalomyelitis mice. | 2013 | NMR Biomed | pmid:23939596 |
| Morris RC et al. | Activation of transfer RNA-guanine ribosyltransferase by protein kinase C. | 1995 | Nucleic Acids Res. | pmid:7630727 |
| Hussar DA | New drugs 2011 part 2. | 2011 | Nursing | pmid:21552174 |
| Birt DF et al. | Inhibition of skin carcinomas but not papillomas by sphingosine, N-methylsphingosine, and N-acetylsphingosine. | 1998 | Nutr Cancer | pmid:9770723 |
| Kartal M et al. | Resveratrol triggers apoptosis through regulating ceramide metabolizing genes in human K562 chronic myeloid leukemia cells. | 2011 | Nutr Cancer | pmid:21500096 |
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| Shou J et al. | Human Dkk-1, a gene encoding a Wnt antagonist, responds to DNA damage and its overexpression sensitizes brain tumor cells to apoptosis following alkylation damage of DNA. | 2002 | Oncogene | pmid:11840333 |
| Deng J et al. | Ceramide does not act as a general second messenger for ultraviolet-induced apoptosis. | 2002 | Oncogene | pmid:11791175 |
| Spiegel S et al. | Endogenous modulators and pharmacological inhibitors of histone deacetylases in cancer therapy. | 2012 | Oncogene | pmid:21725353 |
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| White-Gilbertson S et al. | Ceramide synthase 6 modulates TRAIL sensitivity and nuclear translocation of active caspase-3 in colon cancer cells. | 2009 | Oncogene | pmid:19137010 |
| Kim ES et al. | Inflammatory lipid sphingosine-1-phosphate upregulates C-reactive protein via C/EBPβ and potentiates breast cancer progression. | 2014 | Oncogene | pmid:23955082 |
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| Morales A et al. | Pharmacological inhibition or small interfering RNA targeting acid ceramidase sensitizes hepatoma cells to chemotherapy and reduces tumor growth in vivo. | 2007 | Oncogene | pmid:16862171 |
| Härmä V et al. | Lysophosphatidic acid and sphingosine-1-phosphate promote morphogenesis and block invasion of prostate cancer cells in three-dimensional organotypic models. | 2012 | Oncogene | pmid:21996742 |
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| Malchinkhuu E et al. | Role of p38 mitogen-activated kinase and c-Jun terminal kinase in migration response to lysophosphatidic acid and sphingosine-1-phosphate in glioma cells. | 2005 | Oncogene | pmid:16007180 |
| Albinet V et al. | Dual role of sphingosine kinase-1 in promoting the differentiation of dermal fibroblasts and the dissemination of melanoma cells. | 2014 | Oncogene | pmid:23893239 |
| Takai N et al. | C2-ceramide exhibits antiproliferative activity and potently induces apoptosis in endometrial carcinoma. | 2005 | Oncol. Rep. | pmid:16211298 |
| Doan NB et al. | Acid ceramidase confers radioresistance to glioblastoma cells. | 2017 | Oncol. Rep. | pmid:28765947 |
| Xiong H et al. | SphK1 confers resistance to apoptosis in gastric cancer cells by downregulating Bim via stimulating Akt/FoxO3a signaling. | 2014 | Oncol. Rep. | pmid:25109605 |
| Deguchi Y et al. | The S1P receptor modulator FTY720 prevents the development of experimental colitis in mice. | 2006 | Oncol. Rep. | pmid:16969482 |
| Kao MC et al. | In vitro gene transfer in mammalian cells via a new cationic liposome formulation. | 1998 May-Jun | Oncol. Rep. | pmid:9538164 |
| Choi SY et al. | Phytosphingosine in combination with TRAIL sensitizes cancer cells to TRAIL through synergistic up-regulation of DR4 and DR5. | 2007 | Oncol. Rep. | pmid:17143496 |
| Zhang L et al. | FTY720 for cancer therapy (Review). | 2013 | Oncol. Rep. | pmid:24100923 |
| Hossain Z et al. | Sphingoid bases from sea cucumber induce apoptosis in human hepatoma HepG2 cells through p-AKT and DR5. | 2013 | Oncol. Rep. | pmid:23291741 |
| Gao XY et al. | Inhibition of sphingosine-1-phosphate phosphatase 1 promotes cancer cells migration in gastric cancer: Clinical implications. | 2015 | Oncol. Rep. | pmid:26239167 |
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| Evangelisti C et al. | Assessment of the effect of sphingosine kinase inhibitors on apoptosis,unfolded protein response and autophagy of T-cell acute lymphoblastic leukemia cells; indications for novel therapeutics. | 2014 | Oncotarget | pmid:25226616 |
| Bien-Möller S et al. | Expression of S1P metabolizing enzymes and receptors correlate with survival time and regulate cell migration in glioblastoma multiforme. | 2016 | Oncotarget | pmid:26887055 |
| Fan Q et al. | Sphingosine-1-phosphate promotes ovarian cancer cell proliferation by disrupting Hippo signaling. | 2017 | Oncotarget | pmid:28460443 |
| Beach JA et al. | Sphingosine kinase 1 is required for TGF-β mediated fibroblastto- myofibroblast differentiation in ovarian cancer. | 2016 | Oncotarget | pmid:26716409 |
| Xu R et al. | Alkaline ceramidase 2 and its bioactive product sphingosine are novel regulators of the DNA damage response. | 2016 | Oncotarget | pmid:26943039 |
| Tan SF et al. | Acid ceramidase is upregulated in AML and represents a novel therapeutic target. | 2016 | Oncotarget | pmid:27825124 |
| Li S et al. | Sphk1 promotes breast epithelial cell proliferation via NF-κB-p65-mediated cyclin D1 expression. | 2016 | Oncotarget | pmid:27811358 |
| Neubauer HA et al. | An oncogenic role for sphingosine kinase 2. | 2016 | Oncotarget | pmid:27588496 |
| Zeng Y et al. | Sphingosine-1-phosphate induced epithelial-mesenchymal transition of hepatocellular carcinoma via an MMP-7/ syndecan-1/TGF-β autocrine loop. | 2016 | Oncotarget | pmid:27556509 |
| Dai L et al. | Ceramides promote apoptosis for virus-infected lymphoma cells through induction of ceramide synthases and viral lytic gene expression. | 2015 | Oncotarget | pmid:26327294 |
| Adamiak M et al. | Evidence for the involvement of sphingosine-1-phosphate in the homing and engraftment of hematopoietic stem cells to bone marrow. | 2015 | Oncotarget | pmid:26299919 |
| Grammatikos G et al. | Serum sphingolipidomic analyses reveal an upregulation of C16-ceramide and sphingosine-1-phosphate in hepatocellular carcinoma. | 2016 | Oncotarget | pmid:26933996 |
| Chen MH et al. | Identification of SPHK1 as a therapeutic target and marker of poor prognosis in cholangiocarcinoma. | 2015 | Oncotarget | pmid:26090720 |
| Woodcock JM et al. | Destabilisation of dimeric 14-3-3 proteins as a novel approach to anti-cancer therapeutics. | 2015 | Oncotarget | pmid:25971334 |
| Kim HJ et al. | Novel involvement of RhebL1 in sphingosylphosphorylcholine-induced keratin phosphorylation and reorganization: Binding to and activation of AKT1. | 2017 | Oncotarget | pmid:28209923 |
| Ader I et al. | Neutralizing S1P inhibits intratumoral hypoxia, induces vascular remodelling and sensitizes to chemotherapy in prostate cancer. | 2015 | Oncotarget | pmid:25915662 |
| Zarbin MA et al. | Ophthalmic evaluations in clinical studies of fingolimod (FTY720) in multiple sclerosis. | 2013 | Ophthalmology | pmid:23531349 |
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| Cheng JM et al. | A divergent approach to the synthesis of iGb3 sugar and lipid analogues via a lactosyl 2-azido-sphingosine intermediate. | 2014 | Org. Biomol. Chem. | pmid:24652424 |
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sphingosine
sphingosine is a lipid of Sphingolipids (SP) class.
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