sphingosine

sphingosine is a lipid of Sphingolipids (SP) class.

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There are no associated biomedical information in the current reference collection.

Current reference collection contains 26061 references associated with sphingosine in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

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Authors Title Published Journal PubMed Link
Kulinski JM et al. Sphingosine-1-phosphate and other lipid mediators generated by mast cells as critical players in allergy and mast cell function. 2016 Eur. J. Pharmacol. pmid:25941085
Zamora-Pineda J et al. Dendritic cell sphingosine-1-phosphate lyase regulates thymic egress. 2016 J. Exp. Med. pmid:27810923
Morillon YM et al. Antibody Binding to CD4 Induces Rac GTPase Activation and Alters T Cell Migration. 2016 J. Immunol. pmid:27694496
Lepannetier S et al. Sphingosine-1-phosphate-activated TRPC1 channel controls chemotaxis of glioblastoma cells. 2016 Cell Calcium pmid:27638096
Hashimoto Y et al. Sphingosine-1-phosphate-enhanced Wnt5a promotes osteogenic differentiation in C3H10T1/2 cells. 2016 Cell Biol. Int. pmid:27486054
Viswanathan P et al. Differential elastic responses to barrier-altering agonists in two types of human lung endothelium. 2016 Biochem. Biophys. Res. Commun. pmid:27473658
Moruno Manchon JF et al. SPHK1/sphingosine kinase 1-mediated autophagy differs between neurons and SH-SY5Y neuroblastoma cells. 2016 Autophagy pmid:27467777
Nagahashi M et al. The roles of bile acids and sphingosine-1-phosphate signaling in the hepatobiliary diseases. 2016 J. Lipid Res. pmid:27459945
Juif PE et al. Clinical pharmacology, efficacy, and safety aspects of sphingosine-1-phosphate receptor modulators. 2016 Expert Opin Drug Metab Toxicol pmid:27249325
Hollands A et al. Natural Product Anacardic Acid from Cashew Nut Shells Stimulates Neutrophil Extracellular Trap Production and Bactericidal Activity. 2016 J. Biol. Chem. pmid:27226531
Mirzaian M et al. Accurate quantification of sphingosine-1-phosphate in normal and Fabry disease plasma, cells and tissues by LC-MS/MS with (13)C-encoded natural S1P as internal standard. 2016 Clin. Chim. Acta pmid:27221202
Bao XH et al. [Role and related mechanism of S1P/S1P1 signal pathway during post conditioning of hypertrophic cardiomyocytes]. 2016 Zhonghua Xin Xue Guan Bing Za Zhi pmid:27220580
Resop RS et al. Sphingosine-1-phosphate/sphingosine-1-phosphate receptor 1 signaling is required for migration of naive human T cells from the thymus to the periphery. 2016 J. Allergy Clin. Immunol. pmid:27056271
Mi JN et al. New Immunosuppressive Sphingoid Base and Ceramide Analogues in Wild Cordyceps. 2016 Sci Rep pmid:27966660
Guo J et al. Identification and synthesis of potent and selective pyridyl-isoxazole based agonists of sphingosine-1-phosphate 1 (S1P1). 2016 Bioorg. Med. Chem. Lett. pmid:27055941
Trinh HK et al. Exploration of the Sphingolipid Metabolite, Sphingosine-1-phosphate and Sphingosine, as Novel Biomarkers for Aspirin-exacerbated Respiratory Disease. 2016 Sci Rep pmid:27830727
Adams DR et al. Sphingosine Kinases: Emerging Structure-Function Insights. 2016 Trends Biochem. Sci. pmid:27021309
Fujii C et al. Altered T cell phenotypes associated with clinical relapse of multiple sclerosis patients receiving fingolimod therapy. 2016 Sci Rep pmid:27752051
Puli MR et al. Stomatal closure induced by phytosphingosine-1-phosphate and sphingosine-1-phosphate depends on nitric oxide and pH of guard cells in Pisum sativum. 2016 Planta pmid:27233507
Park K et al. ER stress stimulates production of the key antimicrobial peptide, cathelicidin, by forming a previously unidentified intracellular S1P signaling complex. 2016 Proc. Natl. Acad. Sci. U.S.A. pmid:26903652
Bien-Möller S et al. Expression of S1P metabolizing enzymes and receptors correlate with survival time and regulate cell migration in glioblastoma multiforme. 2016 Oncotarget pmid:26887055
Uranbileg B et al. Increased mRNA Levels of Sphingosine Kinases and S1P Lyase and Reduced Levels of S1P Were Observed in Hepatocellular Carcinoma in Association with Poorer Differentiation and Earlier Recurrence. 2016 PLoS ONE pmid:26886371
Olmo ED et al. Efficacious In Vitro and In Vivo Effects of Dihydrosphingosine-Ethambutol Analogues Against Susceptible and Multi-drug-resistant Mycobacterium tuberculosis. 2016 Arch. Med. Res. pmid:27664485
Arias SL et al. Toxin distribution and sphingoid base imbalances in Fusarium verticillioides-infected and fumonisin B1-watered maize seedlings. 2016 Phytochemistry pmid:26903312
Zhang Y et al. Ceramide Production Mediates Aldosterone-Induced Human Umbilical Vein Endothelial Cell (HUVEC) Damages. 2016 PLoS ONE pmid:26788916
Dillmann C et al. S1PR4 Signaling Attenuates ILT 7 Internalization To Limit IFN-α Production by Human Plasmacytoid Dendritic Cells. 2016 J. Immunol. pmid:26783340
Ghasemi R et al. Integrated sphingosine-1 phosphate signaling in the central nervous system: From physiological equilibrium to pathological damage. 2016 Pharmacol. Res. pmid:26772814
Morel S et al. Sphingosine-1-phosphate reduces ischaemia-reperfusion injury by phosphorylating the gap junction protein Connexin43. 2016 Cardiovasc. Res. pmid:26762268
Sundaram K et al. Loss of neutral ceramidase protects cells from nutrient- and energy -deprivation-induced cell death. 2016 Biochem. J. pmid:26747710
Maczis M et al. Sphingosine-1-phosphate and estrogen signaling in breast cancer. 2016 Adv Biol Regul pmid:26601898
Zhang F et al. Sphingosine 1-phosphate signaling contributes to cardiac inflammation, dysfunction, and remodeling following myocardial infarction. 2016 Am. J. Physiol. Heart Circ. Physiol. pmid:26589326
Pyne NJ and Tigyi GJ A reflection of the lasting contributions from Dr. Robert Bittman to sterol trafficking, sphingolipid and phospholipid research. 2016 Prog. Lipid Res. pmid:26584871
Li S et al. Sphk1 promotes breast epithelial cell proliferation via NF-κB-p65-mediated cyclin D1 expression. 2016 Oncotarget pmid:27811358
Priyadarsini S et al. Complete metabolome and lipidome analysis reveals novel biomarkers in the human diabetic corneal stroma. 2016 Exp. Eye Res. pmid:27742548
Veltman M et al. Correction of lung inflammation in a F508del CFTR murine cystic fibrosis model by the sphingosine-1-phosphate lyase inhibitor LX2931. 2016 Am. J. Physiol. Lung Cell Mol. Physiol. pmid:27663991
Scotti L et al. Sphingosine-1-phosphate restores endothelial barrier integrity in ovarian hyperstimulation syndrome. 2016 Mol. Hum. Reprod. pmid:27645281
Tölle M et al. Regulation of endothelial nitric oxide synthase activation in endothelial cells by S1P1 and S1P3. 2016 Biochem. Biophys. Res. Commun. pmid:27282481
Uemura M et al. Inhibitory Effect of Dihydrosphingosine with α-Tocopherol on Volatile Formation during the Autoxidation of Polyunsaturated Triacylglycerols. 2016 J Oleo Sci pmid:27477074
Liu B et al. Synthetic Studies on a Pachastrissamine Sulfur Analogue: Synthesis of a 4-epi-Sulfur Analogue. 2016 Chem. Pharm. Bull. pmid:27039834
Benaim G et al. Sphingosine inhibits the sarco(endo)plasmic reticulum Ca(2+)-ATPase (SERCA) activity. 2016 Biochem. Biophys. Res. Commun. pmid:27033604
Mezeiová E et al. Total synthesis and antiproliferative/cytotoxic profiling of 2-epi-jaspine B. 2016 Carbohydr. Res. pmid:26895543
Cohen MV et al. Cangrelor-Mediated Cardioprotection Requires Platelets and Sphingosine Phosphorylation. 2016 Cardiovasc Drugs Ther pmid:26780906
Fang J et al. N,N-dimethylsphingosine attenuates myocardial ischemia-reperfusion injury by recruiting regulatory T cells through PI3K/Akt pathway in mice. 2016 Basic Res. Cardiol. pmid:27048490
Tani K et al. Hair Cell Loss Induced by Sphingosine and a Sphingosine Kinase Inhibitor in the Rat Cochlea. 2016 Neurotox Res pmid:26472207
Kim BJ et al. The effect of sphingosine-1-phosphate on bone metabolism in humans depends on its plasma/bone marrow gradient. 2016 J. Endocrinol. Invest. pmid:26219613
Racca V et al. Response to letter regarding article 'Fingolimod effects on left ventricular function in multiple sclerosis'. 2016 Mult. Scler. pmid:26359278
Bakshi R and Häring DA Comment on "Fingolimod effects on left ventricular function in multiple sclerosis" Mult Scler 2015. 2016 Mult. Scler. pmid:26359277
Balakrishnan P et al. Ceramide and N,N,N-Trimethylphytosphingosine-Iodide (TMP-I)-Based Lipid Nanoparticles for Cancer Therapy. 2016 Pharm. Res. pmid:26337769
Touat-Hamici Z et al. Role of lipid phosphate phosphatase 3 in human aortic endothelial cell function. 2016 Cardiovasc. Res. pmid:27694435
Medina CB and Ravichandran KS Do not let death do us part: 'find-me' signals in communication between dying cells and the phagocytes. 2016 Cell Death Differ. pmid:26891690