| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Gennero I et al. | Apoptotic effect of sphingosine 1-phosphate and increased sphingosine 1-phosphate hydrolysis on mesangial cells cultured at low cell density. | 2002 | J. Biol. Chem. | pmid:11821388 |
| Czyborra P et al. | Transient relaxation of rat mesenteric microvessels by ceramides. | 2002 | Br. J. Pharmacol. | pmid:11815377 |
| Ohanian J and Ohanian V | Sphingolipids in mammalian cell signalling. | 2001 | Cell. Mol. Life Sci. | pmid:11814056 |
| Kahan BD | Update on pharmacokinetic/pharmacodynamic studies with FTY720 and sirolimus. | 2002 | Ther Drug Monit | pmid:11805722 |
| Abousalham A et al. | Cell-permeable ceramides preferentially inhibit coated vesicle formation and exocytosis in Chinese hamster ovary compared with Madin-Darby canine kidney cells by preventing the membrane association of ADP-ribosylation factor. | 2002 | Biochem. J. | pmid:11802796 |
| Montes LR et al. | Membrane restructuring via ceramide results in enhanced solute efflux. | 2002 | J. Biol. Chem. | pmid:11796726 |
| El Bawab S et al. | Substrate specificity of rat brain ceramidase. | 2002 | J. Lipid Res. | pmid:11792733 |
| Cabrero A et al. | Increased reactive oxygen species production down-regulates peroxisome proliferator-activated alpha pathway in C2C12 skeletal muscle cells. | 2002 | J. Biol. Chem. | pmid:11792699 |
| Benaud C et al. | Sphingosine 1-phosphate, present in serum-derived lipoproteins, activates matriptase. | 2002 | J. Biol. Chem. | pmid:11792696 |
| Colombaioni L et al. | Serum deprivation increases ceramide levels and induces apoptosis in undifferentiated HN9.10e cells. | 2002 | Neurochem. Int. | pmid:11792463 |
| Jendiroba DB et al. | Effective cytotoxicity against human leukemias and chemotherapy-resistant leukemia cell lines by N-N-dimethylsphingosine. | 2002 | Leuk. Res. | pmid:11792420 |
| Deng J et al. | Ceramide does not act as a general second messenger for ultraviolet-induced apoptosis. | 2002 | Oncogene | pmid:11791175 |
| Rikitake Y et al. | Involvement of endothelial nitric oxide in sphingosine-1-phosphate-induced angiogenesis. | 2002 | Arterioscler. Thromb. Vasc. Biol. | pmid:11788469 |
| Baker RR and Chang H | Phosphatidic acid is the prominent product of endogenous neuronal nuclear lipid phosphorylation, an activity enhanced by sphingosine, linked to phospholipase C and associated with the nuclear envelope. | 2001 | Biochim. Biophys. Acta | pmid:11786297 |
| Okajima F | [Establishment of the method for the measurement of sphingosine-1-phosphate in biological samples and its application for S1P research]. | 2001 | Nippon Yakurigaku Zasshi | pmid:11778456 |
| Kawano Y et al. | Synergistic effect of interleukin-1alpha and ceramide analogue on production of prostaglandin E2 and F2alpha by endometrial stromal cells. | 2001 | Am. J. Reprod. Immunol. | pmid:11775008 |
| Sullards MC and Merrill AH | Analysis of sphingosine 1-phosphate, ceramides, and other bioactive sphingolipids by high-performance liquid chromatography-tandem mass spectrometry. | 2001 | Sci. STKE | pmid:11752637 |
| Kralik SF et al. | Ceramide and glucosamine antagonism of alternate signaling pathways regulating insulin- and osmotic shock-induced glucose transporter 4 translocation. | 2002 | Endocrinology | pmid:11751589 |
| Pollock J et al. | TNF-alpha receptors simultaneously activate Ca2+ mobilisation and stress kinases in cultured sensory neurones. | 2002 | Neuropharmacology | pmid:11750919 |
| Fujino M et al. | T-cell apoptosis triggered by FTY720 via mitochondrial pathway. | Transplant. Proc. | pmid:11750325 | |
| Kahan BD | FTY720: a new dimension in transplantation. | Transplant. Proc. | pmid:11750324 | |
| Brinkmann V et al. | FTY720: dissection of membrane receptor-operated, stereospecific effects on cell migration from receptor-independent antiproliferative and apoptotic effects. | Transplant. Proc. | pmid:11750323 | |
| Chen S et al. | FTY720, a novel transplantation drug, modulates lymphocyte migratory responses to chemokines. | Transplant. Proc. | pmid:11750317 | |
| Henning G et al. | CC chemokine receptor 7-dependent and -independent pathways for lymphocyte homing: modulation by FTY720. | 2001 | J. Exp. Med. | pmid:11748287 |
| Porcelli AM et al. | Phospholipase D stimulation is required for sphingosine-1-phosphate activation of actin stress fibre assembly in human airway epithelial cells. | 2002 | Cell. Signal. | pmid:11747992 |
| Levery SB et al. | Comparative analysis of glycosylinositol phosphorylceramides from fungi by electrospray tandem mass spectrometry with low-energy collision-induced dissociation of Li(+) adduct ions. | 2001 | Rapid Commun. Mass Spectrom. | pmid:11746891 |
| Friedrichs GS et al. | Sphingosine modulates myocyte electrophysiology, induces negative inotropy, and decreases survival after myocardial ischemia. | 2002 | J. Cardiovasc. Pharmacol. | pmid:11743224 |
| Ancellin N et al. | Extracellular export of sphingosine kinase-1 enzyme. Sphingosine 1-phosphate generation and the induction of angiogenic vascular maturation. | 2002 | J. Biol. Chem. | pmid:11741921 |
| Alemany R et al. | Depolarisation induces rapid and transient formation of intracellular sphingosine-1-phosphate. | 2001 | FEBS Lett. | pmid:11741596 |
| Pitson SM et al. | A point mutant of human sphingosine kinase 1 with increased catalytic activity. | 2001 | FEBS Lett. | pmid:11741582 |
| Tosaka M et al. | Sphingosine 1-phosphate contracts canine basilar arteries in vitro and in vivo: possible role in pathogenesis of cerebral vasospasm. | 2001 | Stroke | pmid:11739995 |
| Kim DK et al. | Adaptive concentrations of hydrogen peroxide suppress cell death by blocking the activation of SAPK/JNK pathway. | 2001 | J. Cell. Sci. | pmid:11739664 |
| Muraki K and Imaizumi Y | A novel function of sphingosine-1-phosphate to activate a non-selective cation channel in human endothelial cells. | 2001 | J. Physiol. (Lond.) | pmid:11731576 |
| Hla T et al. | Lysophospholipids--receptor revelations. | 2001 | Science | pmid:11729304 |
| Lampasso JD et al. | Sphingosine-1-phosphate effects on PKC isoform expression in human osteoblastic cells. | 2001 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:11728164 |
| Tamura K et al. | Characterization of an Arabidopsis cDNA encoding a subunit of serine palmitoyltransferase, the initial enzyme in sphingolipid biosynthesis. | 2001 | Plant Cell Physiol. | pmid:11726713 |
| Rosenfeldt HM et al. | EDG-1 links the PDGF receptor to Src and focal adhesion kinase activation leading to lamellipodia formation and cell migration. | 2001 | FASEB J. | pmid:11726541 |
| Friant S et al. | Sphingoid base signaling via Pkh kinases is required for endocytosis in yeast. | 2001 | EMBO J. | pmid:11726514 |
| Tigyi G | Selective ligands for lysophosphatidic acid receptor subtypes: gaining control over the endothelial differentiation gene family. | 2001 | Mol. Pharmacol. | pmid:11723220 |
| Bourbon NA et al. | Ceramide-induced inhibition of Akt is mediated through protein kinase Czeta: implications for growth arrest. | 2002 | J. Biol. Chem. | pmid:11723139 |
| Bulanova E et al. | The IL-15R alpha chain signals through association with Syk in human B cells. | 2001 | J. Immunol. | pmid:11714793 |
| Abnet CC et al. | Sphingolipids as biomarkers of fumonisin exposure and risk of esophageal squamous cell carcinoma in china. | 2001 | Cancer Causes Control | pmid:11714110 |
| Manggau M et al. | 1Alpha,25-dihydroxyvitamin D3 protects human keratinocytes from apoptosis by the formation of sphingosine-1-phosphate. | 2001 | J. Invest. Dermatol. | pmid:11710939 |
| Rosenfeldt HM et al. | The sphingosine-1-phosphate receptor EDG-1 is essential for platelet-derived growth factor-induced cell motility. | 2001 | Biochem. Soc. Trans. | pmid:11709084 |
| Im DS et al. | Characterization of the human and mouse sphingosine 1-phosphate receptor, S1P5 (Edg-8): structure-activity relationship of sphingosine1-phosphate receptors. | 2001 | Biochemistry | pmid:11705398 |
| Dudnik LB et al. | Effect of bilirubin on lipid peroxidation, sphingomyelinase activity, and apoptosis induced by sphingosine and UV irradiation. | 2001 | Biochemistry Mosc. | pmid:11703186 |
| Iwamori M et al. | Specific tritium labeling of cerebrosides at the 3-positions of erythro-sphingosine and threo-sphingosine. | 1975 | J. Lipid Res. | pmid:1170270 |
| Lester RL and Dickson RC | High-performance liquid chromatography analysis of molecular species of sphingolipid-related long chain bases and long chain base phosphates in Saccharomyces cerevisiae after derivatization with 6-aminoquinolyl-N-hydroxysuccinimidyl carbamate. | 2001 | Anal. Biochem. | pmid:11700984 |
| Yoshida A and Ueda H | Neurobiology of the Edg2 lysophosphatidic acid receptor. | 2001 | Jpn. J. Pharmacol. | pmid:11700008 |
| Hornuss C et al. | Human and rat alveolar macrophages express multiple EDG receptors. | 2001 | Eur. J. Pharmacol. | pmid:11698050 |
| Lyons JM and Karin NJ | A role for G protein-coupled lysophospholipid receptors in sphingolipid-induced Ca2+ signaling in MC3T3-E1 osteoblastic cells. | 2001 | J. Bone Miner. Res. | pmid:11697799 |
| Castillo SS and Teegarden D | Ceramide conversion to sphingosine-1-phosphate is essential for survival in C3H10T1/2 cells. | 2001 | J. Nutr. | pmid:11694603 |
| Hanna AN et al. | Tumor necrosis factor-alpha induces stress fiber formation through ceramide production: role of sphingosine kinase. | 2001 | Mol. Biol. Cell | pmid:11694593 |
| Breimer ME | Distribution of molecular species of sphingomyelins in different parts of bovine digestive tract. | 1975 | J. Lipid Res. | pmid:1168686 |
| Roig J et al. | Cdc42-independent activation and translocation of the cytostatic p21-activated protein kinase gamma-PAK by sphingosine. | 2001 | FEBS Lett. | pmid:11684097 |
| Solfrizzo M et al. | In vitro and in vivo studies to assess the effectiveness of cholestyramine as a binding agent for fumonisins. | 2001 | Mycopathologia | pmid:11678589 |
| Cuvillier O and Levade T | Sphingosine 1-phosphate antagonizes apoptosis of human leukemia cells by inhibiting release of cytochrome c and Smac/DIABLO from mitochondria. | 2001 | Blood | pmid:11675357 |
| Sprong H et al. | Glycosphingolipids are required for sorting melanosomal proteins in the Golgi complex. | 2001 | J. Cell Biol. | pmid:11673476 |
| Siehler S et al. | Sphingosine 1-phosphate activates nuclear factor-kappa B through Edg receptors. Activation through Edg-3 and Edg-5, but not Edg-1, in human embryonic kidney 293 cells. | 2001 | J. Biol. Chem. | pmid:11673450 |
| Fujino M et al. | Activation of caspases and mitochondria in FTY720-mediated apoptosis in human T cell line Jurkat. | 2001 | Int. Immunopharmacol. | pmid:11606032 |
| Wang DA et al. | A single amino acid determines lysophospholipid specificity of the S1P1 (EDG1) and LPA1 (EDG2) phospholipid growth factor receptors. | 2001 | J. Biol. Chem. | pmid:11604399 |
| Dalla Libera L et al. | Apoptosis in the skeletal muscle of rats with heart failure is associated with increased serum levels of TNF-alpha and sphingosine. | 2001 | J. Mol. Cell. Cardiol. | pmid:11603928 |
| Viani P et al. | Nitric oxide production in living neurons is modulated by sphingosine: a fluorescence microscopy study. | 2001 | FEBS Lett. | pmid:11602242 |
| Kim MS et al. | Fumonisin B(1) induces apoptosis in LLC-PK(1) renal epithelial cells via a sphinganine- and calmodulin-dependent pathway. | 2001 | Toxicol. Appl. Pharmacol. | pmid:11601888 |
| Guidarelli A et al. | TNFalpha enhances the DNA single-strand breakage induced by the short-chain lipid hydroperoxide analogue tert-butylhydroperoxide via ceramide-dependent inhibition of complex III followed by enforced superoxide and hydrogen peroxide formation. | 2001 | Exp. Cell Res. | pmid:11597127 |
| Higuchi K et al. | Sphingosylphosphorylcholine is an activator of transglutaminase activity in human keratinocytes. | 2001 | J. Lipid Res. | pmid:11590211 |
| Cho S et al. | Role of palmitoyl-protein thioesterase in cell death: implications for infantile neuronal ceroid lipofuscinosis. | 2001 | Eur. J. Paediatr. Neurol. | pmid:11589008 |
| Pato C et al. | Potential application of plant lipid transfer proteins for drug delivery. | 2001 | Biochem. Pharmacol. | pmid:11585052 |
| Abnet CC et al. | A cross-sectional study of human serum sphingolipids, diet and physiologic parameters. | 2001 | J. Nutr. | pmid:11584099 |
| Alfonso A et al. | Prolactin induces calcium influx and release from intracellular pools in human T lymphocytes by activation of tyrosine kinases. | 2001 | Cell. Signal. | pmid:11583917 |
| Lee MJ et al. | Akt-mediated phosphorylation of the G protein-coupled receptor EDG-1 is required for endothelial cell chemotaxis. | 2001 | Mol. Cell | pmid:11583630 |
| KÃ¥gedal K et al. | Sphingosine-induced apoptosis is dependent on lysosomal proteases. | 2001 | Biochem. J. | pmid:11583579 |
| Brinkmann V et al. | FTY720: altered lymphocyte traffic results in allograft protection. | 2001 | Transplantation | pmid:11571432 |
| Caruso-Neves C et al. | Cytoskeleton elements mediate the inhibition of the (Na++K+)atpase activity by PKC in Rhodnius prolixus malpighian tubules during hyperosmotic shock. | 2001 | Arch. Insect Biochem. Physiol. | pmid:11568967 |
| Yang MS et al. | Sphingomyelinase but not ceramide induces nitric oxide synthase expression in rat brain microglia. | 2001 | Neurosci. Lett. | pmid:11567796 |
| Li G et al. | Sphingosine-1-phosphate lyase has a central role in the development of Dictyostelium discoideum. | 2001 | Development | pmid:11566853 |
| Ito Y et al. | Structural requirements of sphingosine molecules for inhibition of DNA primase: biochemical and computational analyses. | 2001 | Biochemistry | pmid:11560507 |
| Schmelz EM et al. | Modulation of intracellular beta-catenin localization and intestinal tumorigenesis in vivo and in vitro by sphingolipids. | 2001 | Cancer Res. | pmid:11559543 |
| Kluk MJ and Hla T | Role of the sphingosine 1-phosphate receptor EDG-1 in vascular smooth muscle cell proliferation and migration. | 2001 | Circ. Res. | pmid:11557736 |
| Erl W and Siess W | Sphingosine-1-phosphate and the leading Edg-1 of vascular smooth muscle cells. | 2001 | Circ. Res. | pmid:11557732 |
| Prinetti A et al. | Immunoseparation of sphingolipid-enriched membrane domains enriched in Src family protein tyrosine kinases and in the neuronal adhesion molecule TAG-1 by anti-GD3 ganglioside monoclonal antibody. | 2001 | J. Neurochem. | pmid:11553690 |
| Marletta MA | Another activation switch for endothelial nitric oxide synthase: why does it have to be so complicated? | 2001 | Trends Biochem. Sci. | pmid:11551775 |
| Singh IN et al. | Ceramide inhibition of mammalian phospholipase D1 and D2 activities is antagonized by phosphatidylinositol 4,5-bisphosphate. | 2001 | Biochemistry | pmid:11551222 |
| Karliner JS et al. | The lysophospholipids sphingosine-1-phosphate and lysophosphatidic acid enhance survival during hypoxia in neonatal rat cardiac myocytes. | 2001 | J. Mol. Cell. Cardiol. | pmid:11549349 |
| Robert P et al. | EDG1 receptor stimulation leads to cardiac hypertrophy in rat neonatal myocytes. | 2001 | J. Mol. Cell. Cardiol. | pmid:11549339 |
| Nadal A et al. | Glial cell responses to lipids bound to albumin in serum and plasma. | 2001 | Prog. Brain Res. | pmid:11545003 |
| Garcia JG et al. | Sphingosine 1-phosphate promotes endothelial cell barrier integrity by Edg-dependent cytoskeletal rearrangement. | 2001 | J. Clin. Invest. | pmid:11544274 |
| Wagenknecht B et al. | C2-ceramide signaling in glioma cells: synergistic enhancement of CD95-mediated, caspase-dependent apoptosis. | 2001 | Cell Death Differ. | pmid:11536010 |
| Zhu K et al. | Sphingosylphosphorylcholine and lysophosphatidylcholine are ligands for the G protein-coupled receptor GPR4. | 2001 | J. Biol. Chem. | pmid:11535583 |
| Ghosh Choudhury G et al. | Ceramide blocks PDGF-induced DNA synthesis in mesangial cells via inhibition of Akt kinase in the absence of apoptosis. | 2001 | Biochem. Biophys. Res. Commun. | pmid:11527425 |
| Morita Y et al. | Regulatory mechanisms of female germ cell apoptosis during embryonic development. | 2001 | Endocr. J. | pmid:11523899 |
| Bhandari N et al. | Gender-related differences in subacute fumonisin B1 hepatotoxicity in BALB/c mice. | 2001 | Toxicology | pmid:11522378 |
| Osawa Y et al. | Sphingosine kinase regulates hepatoma cell differentiation: roles of hepatocyte nuclear factor and retinoid receptor. | 2001 | Biochem. Biophys. Res. Commun. | pmid:11520048 |
| Morley SJ and Pain VM | Proteasome inhibitors and immunosuppressive drugs promote the cleavage of eIF4GI and eIF4GII by caspase-8-independent mechanisms in Jurkat T cell lines. | 2001 | FEBS Lett. | pmid:11513883 |
| Liu H et al. | Reaction of fumonisin with glucose prevents promotion of hepatocarcinogenesis in female F344/N rats while maintaining normal hepatic sphinganine/sphingosine ratios. | 2001 | J. Agric. Food Chem. | pmid:11513718 |
| Miguel BG et al. | Sphingolipid derivatives modulate intracellular Ca2+ in rat synaptosomes. | 2001 | Acta Neurobiol Exp (Wars) | pmid:11512408 |
| Jiang Q et al. | Nuclear translocation of extracellular signal-regulated kinases in neuronal excitotoxicity. | 2001 | Neuroreport | pmid:11496121 |
| Matsubara S and Ozawa M | Expression of alpha-catenin in alpha-catenin-deficient cells increases resistance to sphingosine-induced apoptosis. | 2001 | J. Cell Biol. | pmid:11489917 |
| Loureiro y Penha CV et al. | Characterization of novel structures of mannosylinositolphosphorylceramides from the yeast forms of Sporothrix schenckii. | 2001 | Eur. J. Biochem. | pmid:11488918 |
| Valiente O et al. | Preparation of deacetyl-, lyso-, and deacetyl-lyso-GM(3) by selective alkaline hydrolysis of GM3 ganglioside. | 2001 | J. Lipid Res. | pmid:11483634 |
sphingosine
sphingosine is a lipid of Sphingolipids (SP) class.
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