sphingosine

sphingosine is a lipid of Sphingolipids (SP) class.

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Current reference collection contains 26061 references associated with sphingosine in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

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Authors Title Published Journal PubMed Link
Enkvetchakul B et al. Influences of sphingosine on two-stage skin tumorigenesis in Sencar mice. 1992 Cancer Lett. pmid:1540929
Inokuchi J et al. Sphingosine inhibits attachment of murine Lewis lung carcinoma cells to laminin and type IV collagen. 1991 FEBS Lett. pmid:1864377
Harrison BC et al. Effects of sphingosine on phorbol ester-mediated changes in astrocyte morphology and protein phosphorylation. 1991 J. Neurosci. Res. pmid:1890699
Norris V et al. A protein kinase C-like activity in Escherichia coli. 1991 Mol. Microbiol. pmid:1809838
Mendez AJ et al. Protein kinase C as a mediator of high density lipoprotein receptor-dependent efflux of intracellular cholesterol. 1991 J. Biol. Chem. pmid:1645339
Nishimura K et al. Sphingolipids of a cestode Metroliasthes coturnix. 1991 Biochim. Biophys. Acta pmid:1932097
Roff CF et al. Type C Niemann-Pick disease: use of hydrophobic amines to study defective cholesterol transport. 1991 Dev. Neurosci. pmid:1817037
Agopyan N and Agopyan I Effects of protein kinase C activators and inhibitors on membrane properties, synaptic responses, and cholinergic actions in CA1 subfield of rat hippocampus in situ and in vitro. 1991 Synapse pmid:1882329
Shibata H and Kojima I Involvement of protein kinase C in angiotensin II-mediated release of 12-hydroxyeicosatetraenoic acid in bovine adrenal glomerulosa cells. 1991 Endocrinol. Jpn. pmid:1726634
Ong RC et al. Activation mechanisms of platelet-activating factor in U937 cells: possible involvement of protein kinase C. 1991 Cell. Immunol. pmid:1654212
Rajkumar K et al. Protein kinase C, an endogenous regulator of hormone-induced cyclic AMP induction in porcine luteal cells. 1991 J. Endocrinol. pmid:1655942
Lee HM and Fain JN Phorbol myristate acetate inhibition of phospholipase C activation by carbachol in slices of rat brain cortex is a delayed and indirect effect. 1991 J. Neurochem. pmid:1849548
Thomas TP et al. Dioctanoylglycerol regulation of cytosolic Ca2+ by protein kinase C-independent mechanism in HIT T-15 islet cells. 1991 Diabetes pmid:2022306
Wang E et al. Inhibition of sphingolipid biosynthesis by fumonisins. Implications for diseases associated with Fusarium moniliforme. 1991 J. Biol. Chem. pmid:1860857
Grove DS and Mastro AM Differential activation and inhibition of lymphocyte proliferation by modulators of protein kinase C: diacylglycerols, "rationally designed" activators and inhibitors of protein kinase C. 1991 Exp. Cell Res. pmid:1995292
Candela M et al. Sphingosine synergistically stimulates tumor necrosis factor alpha-induced prostaglandin E2 production in human fibroblasts. 1991 J. Exp. Med. pmid:1836009
Campenot RB et al. Effects of sphingosine, staurosporine, and phorbol ester on neurites of rat sympathetic neurons growing in compartmented cultures. 1991 J. Neurosci. pmid:2010808
Rao GN et al. Na+/H+ antiporter gene expression during monocytic differentiation of HL60 cells. 1991 J. Biol. Chem. pmid:1649822
Kiss Z et al. Ethanol potentiates the stimulatory effects of phorbol ester, sphingosine and 4-hydroxynonenal on the hydrolysis of phosphatidylethanolamine in NIH 3T3 cells. 1991 Eur. J. Biochem. pmid:2029907
Dressler KA et al. Sphingomyelin synthesis is involved in adherence during macrophage differentiation of HL-60 cells. 1991 J. Biol. Chem. pmid:2050663
Paul A et al. Regulation of secretion in cultured tracheal serous cells by protein kinases A and C. 1991 Am. J. Physiol. pmid:1651665
Stein Y et al. Metabolism of 3-[3H]sphingosine sphingomyelin labeled with [14C]palmitic or [14C]linoleic acid by Hep G2 cells and rat liver in vivo. 1991 Biochim. Biophys. Acta pmid:2054378
Worrell RT and Frizzell RA CaMKII mediates stimulation of chloride conductance by calcium in T84 cells. 1991 Am. J. Physiol. pmid:1708204
Raymond JR Protein kinase C induces phosphorylation and desensitization of the human 5-HT1A receptor. 1991 J. Biol. Chem. pmid:1860872
Shayman JA et al. Modulation of renal epithelial cell growth by glucosylceramide. Association with protein kinase C, sphingosine, and diacylglycerol. 1991 J. Biol. Chem. pmid:1744091
Futerman AH and Pagano RE Determination of the intracellular sites and topology of glucosylceramide synthesis in rat liver. 1991 Biochem. J. pmid:1747103
Wiedmer T and Sims PJ Participation of protein kinases in complement C5b-9-induced shedding of platelet plasma membrane vesicles. 1991 Blood pmid:1659468
Weiss RH et al. Sphingosine reverses growth inhibition caused by activation of protein kinase C in vascular smooth muscle cells. 1991 J. Cell. Physiol. pmid:1748721
Mathias S et al. Characterization of a ceramide-activated protein kinase: stimulation by tumor necrosis factor alpha. 1991 Proc. Natl. Acad. Sci. U.S.A. pmid:1946418
McDonald OB et al. Activation of casein kinase II by sphingosine. 1991 J. Biol. Chem. pmid:1939200
McGuinness N et al. The effects of trans-ACPD on long-term potentiation in the rat hippocampal slice. 1991 Neuroreport pmid:1667272
McGuinness N et al. Inhibition of an N-methyl-D-aspartate induced short-term potentiation in the rat hippocampal slice. 1991 Brain Res. pmid:1773345
Miccheli A et al. Modulation of the free sphingosine levels in Epstein Barr virus transformed human B lymphocytes by phorbol dibutyrate. 1991 Biochim. Biophys. Acta pmid:1657192
Jaffrézou JP et al. Reversal of multidrug resistance by calcium channel blocker SR33557 without photoaffinity labeling of P-glycoprotein. 1991 J. Biol. Chem. pmid:1918089
Kanfer JN and McCartney D Sphingosine and unsaturated fatty acids modulate the base exchange enzyme activities of rat brain membranes. 1991 FEBS Lett. pmid:1936252
Khan WA et al. Use of D-erythro-sphingosine as a pharmacological inhibitor of protein kinase C in human platelets. 1991 Biochem. J. pmid:1898331
Fukuda K et al. Histamine H1-receptor-mediated keratan sulfate production in rabbit chondrocytes: involvement of protein kinase C. 1991 Am. J. Physiol. pmid:1887868
Hulkower KI et al. Evidence that responses of articular chondrocytes to interleukin-1 and basic fibroblast growth factor are not mediated by protein kinase C. 1991 Biochem. J. pmid:1645527
Goldkorn T et al. Ceramide stimulates epidermal growth factor receptor phosphorylation in A431 human epidermoid carcinoma cells. Evidence that ceramide may mediate sphingosine action. 1991 J. Biol. Chem. pmid:1874747
Osborne NN et al. Protein kinase C (alpha and beta) immunoreactivity in rabbit and rat retina: effect of phorbol esters and transmitter agonists on immunoreactivity and the translocation of the enzyme from cytosolic to membrane compartments. 1991 J. Neurochem. pmid:2072105
Sugiya H and Furuyama S Sphingosine stimulates calcium mobilization in rat parotid acinar cells. 1991 FEBS Lett. pmid:1864358
Norberg P et al. Characterization of glucosylceramide from plasma membranes of plant root cells. 1991 Biochim. Biophys. Acta pmid:1854789
Sauro MD and Zorn NE Prolactin induces proliferation of vascular smooth muscle cells through a protein kinase C-dependent mechanism. 1991 J. Cell. Physiol. pmid:1860893
Mandon EC et al. Sphingolipid biosynthesis in cultured neurons. Down-regulation of serine palmitoyltransferase by sphingoid bases. 1991 Eur. J. Biochem. pmid:1646717
Miccheli A et al. Modulation of human lymphoblastoid B cell line by phorbol ester and sphingosine. A 31P-NMR study. 1991 Biochim. Biophys. Acta pmid:1646646
Grandin N and Charbonneau M Intracellular pH and intracellular free calcium responses to protein kinase C activators and inhibitors in Xenopus eggs. 1991 Development pmid:1794315
Desai NN and Spiegel S Sphingosylphosphorylcholine is a remarkably potent mitogen for a variety of cell lines. 1991 Biochem. Biophys. Res. Commun. pmid:1958205
Murray MA et al. Role of protein kinase C in bradykinin-induced increases in microvascular permeability. 1991 Circ. Res. pmid:1708311
Endo K et al. Cell membrane signaling as target in cancer therapy: inhibitory effect of N,N-dimethyl and N,N,N-trimethyl sphingosine derivatives on in vitro and in vivo growth of human tumor cells in nude mice. 1991 Cancer Res. pmid:1998952
Nojiri H et al. A specific type of ganglioside as a modulator of insulin-dependent cell growth and insulin receptor tyrosine kinase activity. Possible association of ganglioside-induced inhibition of insulin receptor function and monocytic differentiation induction in HL-60 cells. 1991 J. Biol. Chem. pmid:1999434
Garcia MC et al. C20 polyunsaturated fatty acids and phorbol myristate acetate enhance agonist-stimulated synthesis of 1-radyl-2-acetyl-sn-glycero-3-phosphocholine in vascular endothelial cells. 1991 Biochim. Biophys. Acta pmid:1903305
Elstad MR et al. Protein kinase C regulates the synthesis of platelet-activating factor by human monocytes. 1991 Am. J. Respir. Cell Mol. Biol. pmid:1846746
Zhang H et al. Sphingosine-1-phosphate, a novel lipid, involved in cellular proliferation. 1991 J. Cell Biol. pmid:2050740
Farley J and Schuman E Protein kinase C inhibitors prevent induction and continued expression of cell memory in Hermissenda type B photoreceptors. 1991 Proc. Natl. Acad. Sci. U.S.A. pmid:2000409
Vignery A et al. Macrophages express functional receptors for calcitonin-gene-related peptide. 1991 J. Cell. Physiol. pmid:1721072
Mitsuka M and Berk BC Long-term regulation of Na(+)-H+ exchange in vascular smooth muscle cells: role of protein kinase C. 1991 Am. J. Physiol. pmid:1848402
Okoshi H et al. Cell membrane signaling as target in cancer therapy. II: Inhibitory effect of N,N,N-trimethylsphingosine on metastatic potential of murine B16 melanoma cell line through blocking of tumor cell-dependent platelet aggregation. 1991 Cancer Res. pmid:1657377
Jamal Z et al. Plasma membrane fractions from rat liver contain a phosphatidate phosphohydrolase distinct from that in the endoplasmic reticulum and cytosol. 1991 J. Biol. Chem. pmid:1993672
Mullmann TJ et al. Sphingosine inhibits phosphatidate phosphohydrolase in human neutrophils by a protein kinase C-independent mechanism. 1991 J. Biol. Chem. pmid:1989967
Borek C et al. Long-chain (sphingoid) bases inhibit multistage carcinogenesis in mouse C3H/10T1/2 cells treated with radiation and phorbol 12-myristate 13-acetate. 1991 Proc. Natl. Acad. Sci. U.S.A. pmid:2000399
Taniyama K et al. Expression of the GABAB receptor in Xenopus oocytes and inhibition of the response by activation of protein kinase C. 1991 FEBS Lett. pmid:1846822
Hannun YA et al. Use of sphingosine as inhibitor of protein kinase C. 1991 Meth. Enzymol. pmid:1943771
Bement WM and Capco DG Analysis of inducible contractile rings suggests a role for protein kinase C in embryonic cytokinesis and wound healing. 1991 Cell Motil. Cytoskeleton pmid:1751967
Apgar JR Regulation of the antigen-induced F-actin response in rat basophilic leukemia cells by protein kinase C. 1991 J. Cell Biol. pmid:1825660
Gomez-Muñoz A et al. Unsaturated fatty acids activate glycogen phosphorylase in cultured rat hepatocytes. 1991 Biochem. J. pmid:2039470
Sarafian T et al. The participation of annexin II (calpactin I) in calcium-evoked exocytosis requires protein kinase C. 1991 J. Cell Biol. pmid:1832677
Chakraborti S et al. Protein kinase C dependent and independent activation of phospholipase A2 under calcium ionophore (A23187) exposure in rabbit pulmonary arterial smooth muscle cells. 1991 FEBS Lett. pmid:1906011
White DM and Levine JD Different mechanical transduction mechanisms for the immediate and delayed responses of rat C-fiber nociceptors. 1991 J. Neurophysiol. pmid:1774578
Celada A and Maki RA IFN-gamma induces the expression of the genes for MHC class II I-A beta and tumor necrosis factor through a protein kinase C-independent pathway. 1991 J. Immunol. pmid:1845803
Röder B et al. The determination of phytosphingosine-containing globotriaosylceramide from human kidney in the presence of lactosylceramide. 1990 Chem. Phys. Lipids pmid:2162261
Ulisse S et al. A novel mechanism of action of corticotropin releasing factor in rat Leydig cells. 1990 J. Biol. Chem. pmid:2153673
Fiore S et al. Evaluation of synthetic sphingosine, lysosphingolipids and glycosphingolipids as inhibitors of functional responses of human neutrophils. 1990 Biochem. J. pmid:2155608
Rotem R et al. Protein kinase C is present in human sperm: possible role in flagellar motility. 1990 Proc. Natl. Acad. Sci. U.S.A. pmid:2402510
Suzuki K et al. Human growth hormone-stimulated growth of human cultured lymphocytes (IM-9) and its inhibition by phorbol diesters through down-regulation of the hormone receptors. Possible involvement of phosphorylation of a 55,000 molecular weight protein associated with the receptor in the down-regulation. 1990 J. Biol. Chem. pmid:2358463
Winicov I et al. Sphingosine interacts directly with the receptor complex to inhibit thyrotropin-releasing hormone binding. 1990 Endocrinology pmid:2106432
Bishop WR et al. Regulation of sn-1,2-diacylglycerol second-messenger formation in thrombin-stimulated human platelets. Potentiation by protein kinase C inhibitors. 1990 Biochem. J. pmid:2386487
Elliott MS and Crane DL Protein kinase C modulation of queuine uptake in cultured human fibroblasts. 1990 Biochem. Biophys. Res. Commun. pmid:2118349
Warner JA and MacGlashan DW Signal transduction events in human basophils. A comparative study of the role of protein kinase C in basophils activated by anti-IgE antibody and formyl-methionyl-leucyl-phenylalanine. 1990 J. Immunol. pmid:1697313
Gat-Yablonski G and Sagi-Eisenberg R Differential down-regulation of protein kinase C selectively affects IgE-dependent exocytosis and inositol trisphosphate formation. 1990 Biochem. J. pmid:2241900
Sohal PS and Cornell RB Sphingosine inhibits the activity of rat liver CTP:phosphocholine cytidylyltransferase. 1990 J. Biol. Chem. pmid:2164014
Igarashi Y et al. A specific enhancing effect of N,N-dimethylsphingosine on epidermal growth factor receptor autophosphorylation. Demonstration of its endogenous occurrence (and the virtual absence of unsubstituted sphingosine) in human epidermoid carcinoma A431 cells. 1990 J. Biol. Chem. pmid:2318819
Cambray-Deakin MA et al. Neuritogenesis in cerebellar granule cells in vitro: a role for protein kinase C. 1990 Brain Res. Dev. Brain Res. pmid:2190715
Lauener RP et al. Engagement of the monocyte surface antigen CD14 induces lymphocyte function-associated antigen-1/intercellular adhesion molecule-1-dependent homotypic adhesion. 1990 J. Immunol. pmid:1696596
Sugiya H and Furuyama S Sphingosine increases inositol trisphosphate in rat parotid acinar cells by a mechanism that is independent of protein kinase C but dependent on extracellular calcium. 1990 Cell Calcium pmid:2272081
Bankov I and Barrett J Sphingomyelin synthesis in Fasciola hepatica. 1990 Int. J. Parasitol. pmid:2228421
Igisu H et al. Binding of galactosylsphingosine (psychosine) by albumin. 1990 Lipids pmid:2325508
Ramachandran CK et al. Dexamethasone increases neutral sphingomyelinase activity and sphingosine levels in 3T3-L1 fibroblasts. 1990 Biochem. Biophys. Res. Commun. pmid:2157410
Lavie Y and Liscovitch M Activation of phospholipase D by sphingoid bases in NG108-15 neural-derived cells. 1990 J. Biol. Chem. pmid:2303483
Rice WR et al. P2-purinoceptor regulation of surfactant phosphatidylcholine secretion. Relative roles of calcium and protein kinase C. 1990 Biochem. J. pmid:2317195
Zorn NE et al. The HIV protein, GP120, activates nuclear protein kinase C in nuclei from lymphocytes and brain. 1990 Biochem. Biophys. Res. Commun. pmid:2306233
Jeckel D et al. Sphingomyelin is synthesized in the cis Golgi. 1990 FEBS Lett. pmid:2155131
Wolf BA et al. Diacylglycerol synthesis de novo from glucose by pancreatic islets isolated from rats and humans. 1990 J. Clin. Invest. pmid:2405021
Wertz PW and Downing DT Free sphingosine in human epidermis. 1990 J. Invest. Dermatol. pmid:2299191
Honma Y et al. Inhibition of abl oncogene tyrosine kinase induces erythroid differentiation of human myelogenous leukemia K562 cells. 1990 Jpn. J. Cancer Res. pmid:2125038
Stinavage PS et al. A 59 kiloDalton outer membrane protein of Salmonella typhimurium protects against oxidative intraleukocytic killing due to human neutrophils. 1990 Mol. Microbiol. pmid:2187147
Satoh T and Endou H Inhibitory effect of phorbol ester on sodium transport in frog urinary bladder. 1990 Am. J. Physiol. pmid:2168677
Bement WM and Capco DG Protein kinase C acts downstream of calcium at entry into the first mitotic interphase of Xenopus laevis. 1990 Cell Regul. pmid:2100203
Cox LR et al. Modulation of phosphoinositide metabolism in aortic smooth muscle cells by allylamine. 1990 Exp. Mol. Pathol. pmid:2170166
Trinchera M et al. Recycling of glucosylceramide and sphingosine for the biosynthesis of gangliosides and sphingomyelin in rat liver. 1990 Biochem. J. pmid:2241913
Winkel GK et al. Activation of protein kinase C triggers premature compaction in the four-cell stage mouse embryo. 1990 Dev. Biol. pmid:2407575