| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Lampasso JD et al. | Sphingosine-1-phosphate effects on PKC isoform expression in human osteoblastic cells. | 2001 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:11728164 |
| Carpio LC et al. | Sphingolipids stimulate cell growth via MAP kinase activation in osteoblastic cells. | 1999 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:10670688 |
| Noureddine L et al. | Modulation of total ceramide and constituent ceramide species in the acutely and chronically hypoxic mouse heart at different ages. | 2008 | Prostaglandins Other Lipid Mediat. | pmid:18400538 |
| Snider AJ et al. | Loss of neutral ceramidase increases inflammation in a mouse model of inflammatory bowel disease. | 2012 | Prostaglandins Other Lipid Mediat. | pmid:22940715 |
| Knapp M et al. | Sustained decrease in plasma sphingosine-1-phosphate concentration and its accumulation in blood cells in acute myocardial infarction. | 2013 | Prostaglandins Other Lipid Mediat. | pmid:24120760 |
| Ratajczak MZ et al. | An emerging link in stem cell mobilization between activation of the complement cascade and the chemotactic gradient of sphingosine-1-phosphate. | 2013 Jul-Aug | Prostaglandins Other Lipid Mediat. | pmid:22981511 |
| Kim HL et al. | Characterization of N,N,-dimethyl-D-erythro-sphingosine-induced apoptosis and signaling in U937 cells: independence of sphingosine kinase inhibition. | 2008 | Prostaglandins Other Lipid Mediat. | pmid:18316219 |
| Ahmad M et al. | The effect of hypoxia on lipid phosphate receptor and sphingosine kinase expression and mitogen-activated protein kinase signaling in human pulmonary smooth muscle cells. | 2006 | Prostaglandins Other Lipid Mediat. | pmid:16647641 |
| Linke B et al. | Analysis of sphingolipid and prostaglandin synthesis during zymosan-induced inflammation. | 2012 | Prostaglandins Other Lipid Mediat. | pmid:22732087 |
| Kim HL et al. | Differential signaling of sphingosine derivatives in U937 human monocytes depends on the degree of N-methylation. | 2008 | Prostaglandins Other Lipid Mediat. | pmid:18467142 |
| Olivera A | Unraveling the complexities of sphingosine-1-phosphate function: the mast cell model. | 2008 | Prostaglandins Other Lipid Mediat. | pmid:18403224 |
| Zhang W et al. | Sphingosine-1-phosphate receptor-2 mediated NFκB activation contributes to tumor necrosis factor-α induced VCAM-1 and ICAM-1 expression in endothelial cells. | 2013 | Prostaglandins Other Lipid Mediat. | pmid:23770055 |
| Han M et al. | Effect of direct albumin binding to sphingosylphosphorylcholine in Jurkat T cells. | 2007 | Prostaglandins Other Lipid Mediat. | pmid:17991619 |
| Yatomi Y et al. | Sphingosine 1-phosphate: synthesis and release. | 2001 | Prostaglandins Other Lipid Mediat. | pmid:11324700 |
| Goetzl EJ | Pleiotypic mechanisms of cellular responses to biologically active lysophospholipids. | 2001 | Prostaglandins Other Lipid Mediat. | pmid:11324701 |
| Olivera A and Spiegel S | Sphingosine kinase: a mediator of vital cellular functions. | 2001 | Prostaglandins Other Lipid Mediat. | pmid:11324702 |
| Pulkoski-Gross MJ et al. | Novel sphingosine kinase-1 inhibitor, LCL351, reduces immune responses in murine DSS-induced colitis. | 2017 | Prostaglandins Other Lipid Mediat. | pmid:28377281 |
| Hla T | Sphingosine 1-phosphate receptors. | 2001 | Prostaglandins Other Lipid Mediat. | pmid:11324703 |
| Mandala SM | Sphingosine-1-phosphate phosphatases. | 2001 | Prostaglandins Other Lipid Mediat. | pmid:11324704 |
| Lynch KR and Macdonald TL | Structure activity relationships of lysophospholipid mediators. | 2001 | Prostaglandins Other Lipid Mediat. | pmid:11324706 |
| Panetti TS et al. | Modulation of cell interactions with extracellular matrix by lysophosphatidic acid and sphingosine 1-phosphate. | 2001 | Prostaglandins Other Lipid Mediat. | pmid:11324710 |
| Zabielski P et al. | Activation of PPARα by bezafibrate negatively affects de novo synthesis of sphingolipids in regenerating rat liver. | 2010 | Prostaglandins Other Lipid Mediat. | pmid:20851774 |
| Maceyka M et al. | Sphingosine kinases, sphingosine-1-phosphate and sphingolipidomics. | 2005 | Prostaglandins Other Lipid Mediat. | pmid:16099387 |
| Baranowski M et al. | Pioglitazone induces de novo ceramide synthesis in the rat heart. | 2007 | Prostaglandins Other Lipid Mediat. | pmid:17259076 |
| Chun J | Lysophospholipids in the nervous system. | 2005 | Prostaglandins Other Lipid Mediat. | pmid:16099390 |
| Rosen H | Chemical approaches to the lysophospholipid receptors. | 2005 | Prostaglandins Other Lipid Mediat. | pmid:16099402 |
| Coelho RP et al. | Sphingosine-1-phosphate and oligodendrocytes: from cell development to the treatment of multiple sclerosis. | 2010 | Prostaglandins Other Lipid Mediat. | pmid:19808013 |
| Zabielski P et al. | Partial hepatectomy activates production of the pro-mitotic intermediates of the sphingomyelin signal transduction pathway in the rat liver. | 2007 | Prostaglandins Other Lipid Mediat. | pmid:17499747 |
| Butler J et al. | Functional characterization of sphingosine 1-phosphate receptor agonist in human endothelial cells. | 2004 | Prostaglandins Other Lipid Mediat. | pmid:15165029 |
| Chae SS et al. | Constitutive expression of the S1P1 receptor in adult tissues. | 2004 | Prostaglandins Other Lipid Mediat. | pmid:15165038 |
| Wang XQ et al. | Sphingosylphosphorylcholine induces α-smooth muscle actin expression in human lung fibroblasts and fibroblast-mediated gel contraction via S1P2 receptor and Rho/Rho-kinase pathway. | 2014 | Prostaglandins Other Lipid Mediat. | pmid:24614064 |
| Schmidt H et al. | LC-MS/MS-analysis of sphingosine-1-phosphate and related compounds in plasma samples. | 2006 | Prostaglandins Other Lipid Mediat. | pmid:17085324 |
| Li Z et al. | Role of guanine nucleotide exchange factor P-Rex-2b in sphingosine 1-phosphate-induced Rac1 activation and cell migration in endothelial cells. | 2005 | Prostaglandins Other Lipid Mediat. | pmid:15967165 |
| Cutignano A et al. | UPLC-MS/MS method for analysis of sphingosine 1-phosphate in biological samples. | 2010 | Prostaglandins Other Lipid Mediat. | pmid:20601074 |
| Lee YM et al. | A novel method to quantify sphingosine 1-phosphate by immobilized metal affinity chromatography (IMAC). | 2007 | Prostaglandins Other Lipid Mediat. | pmid:17991617 |
| Thompson B et al. | Protein kinase Calpha and sphingosine 1-phosphate-dependent signaling in endothelial cell. | 2006 | Prostaglandins Other Lipid Mediat. | pmid:16846783 |
| Long JS et al. | The functional PDGFbeta receptor-S1P1 receptor signaling complex is involved in regulating migration of mouse embryonic fibroblasts in response to platelet derived growth factor. | 2006 | Prostaglandins Other Lipid Mediat. | pmid:16846788 |
| Hammad SM et al. | Dual and distinct roles for sphingosine kinase 1 and sphingosine 1 phosphate in the response to inflammatory stimuli in RAW macrophages. | 2008 | Prostaglandins Other Lipid Mediat. | pmid:18166496 |
| Zabielski P et al. | The effect of high-fat diet on the sphingolipid pathway of signal transduction in regenerating rat liver. | 2010 | Prostaglandins Other Lipid Mediat. | pmid:20599517 |
| Gibbs TC et al. | Signal transduction responses to lysophosphatidic acid and sphingosine 1-phosphate in human prostate cancer cells. | 2009 | Prostate | pmid:19536794 |
| Leroux ME et al. | Sphingolipids and the sphingosine kinase inhibitor, SKI II, induce BCL-2-independent apoptosis in human prostatic adenocarcinoma cells. | 2007 | Prostate | pmid:17879964 |
| Sekine Y et al. | HDL and sphingosine-1-phosphate activate stat3 in prostate cancer DU145 cells via ERK1/2 and S1P receptors, and promote cell migration and invasion. | 2011 | Prostate | pmid:20979115 |
| Wang JD et al. | Early induction of apoptosis in androgen-independent prostate cancer cell line by FTY720 requires caspase-3 activation. | 1999 | Prostate | pmid:10344723 |
| Bourquin F et al. | PLP-dependent enzymes as entry and exit gates of sphingolipid metabolism. | 2011 | Protein Sci. | pmid:21710479 |
| Baek S et al. | DJ-1 Regulates Differentiation of Human Mesenchymal Stem Cells into Smooth Muscle-like Cells in Response to Sphingosylphosphorylcholine. | 2017 | Proteomics | pmid:28949093 |
| Mortazavi PN et al. | Possible roles of phospholipase A(2) in the biological activities of Acanthamoeba castellanii (T4 Genotype). | 2011 | Protist | pmid:20650684 |
| Kono Y et al. | Sphingosine kinase 1 regulates mucin production via ERK phosphorylation. | 2010 | Pulm Pharmacol Ther | pmid:19835973 |
| Müller HC et al. | The Sphingosine-1 Phosphate receptor agonist FTY720 dose dependently affected endothelial integrity in vitro and aggravated ventilator-induced lung injury in mice. | 2011 | Pulm Pharmacol Ther | pmid:21419858 |
| von Bismarck P et al. | IKK NBD peptide inhibits LPS induced pulmonary inflammation and alters sphingolipid metabolism in a murine model. | 2012 | Pulm Pharmacol Ther | pmid:22469869 |
| Racké K et al. | Potential role of EDG receptors and lysophospholipids as their endogenous ligands in the respiratory tract. | 2000 | Pulm Pharmacol Ther | pmid:10873548 |
| Levery SB et al. | Comparative analysis of glycosylinositol phosphorylceramides from fungi by electrospray tandem mass spectrometry with low-energy collision-induced dissociation of Li(+) adduct ions. | 2001 | Rapid Commun. Mass Spectrom. | pmid:11746891 |
| Jaschinski T et al. | Laser desorption/ionization mediated by bionanostructures from microalgae. | 2013 | Rapid Commun. Mass Spectrom. | pmid:23239323 |
| Lee MH et al. | Analysis of ceramides in cosmetics by reversed-phase liquid chromatography/electrospray ionization mass spectrometry with collision-induced dissociation. | 2003 | Rapid Commun. Mass Spectrom. | pmid:12478556 |
| Morishige J et al. | A clean-up technology for the simultaneous determination of lysophosphatidic acid and sphingosine-1-phosphate by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry using a phosphate-capture molecule, Phos-tag. | 2010 | Rapid Commun. Mass Spectrom. | pmid:20213695 |
| Renaud JB et al. | Product ion filtering with rapid polarity switching for the detection of all fumonisins and AAL-toxins. | 2015 | Rapid Commun. Mass Spectrom. | pmid:26467225 |
| Jadidi-Niaragh F and Mirshafiey A | Therapeutic approach to multiple sclerosis by novel oral drug. | 2011 | Recent Pat Inflamm Allergy Drug Discov | pmid:21184668 |
| Incorvaia C et al. | Anaphylaxis: an update on its understanding and management. | 2010 | Recent Pat Inflamm Allergy Drug Discov | pmid:20100165 |
| Brunk UT et al. | Lysosomal involvement in apoptosis. | 2001 | Redox Rep. | pmid:11450988 |
| Brunk UT | Lysosomotropic detergents induce time- and dose-dependent apoptosis/necrosis in cultured cells. | 2000 | Redox Rep. | pmid:10939278 |
| Pedrera C et al. | Receptor-independent mechanisms are involved in the priming of neutrophil's oxidase by vasoactive intestinal peptide. | 1994 | Regul. Pept. | pmid:7716283 |
| Djanani A et al. | Agonist function of the neurokinin receptor antagonist, [D-Arg1,D-Phe5,D-Trp7,9,Leu11]substance P, in monocytes. | 2003 | Regul. Pept. | pmid:12972327 |
| Cartus T et al. | Distribution of protein phosphatases type 1 and 2A in RINm5F cells. | 1998 | Regul. Pept. | pmid:9809799 |
| Shi Y et al. | A novel immunosuppressant FTY720 ameliorates proteinuria and alterations of intrarenal adrenomedullin in rats with autoimmune glomerulonephritis. | 2005 | Regul. Pept. | pmid:15680492 |
| Aksu F et al. | Antioxidant and renoprotective effects of sphingosylphosphorylcholine on contrast-induced nephropathy in rats. | 2016 | Ren Fail | pmid:27309733 |
| Ni HF et al. | FTY720 attenuates tubulointerstitial inflammation and fibrosis in subtotally nephrectomized rats. | 2013 | Ren Fail | pmid:23848241 |
| Tsai YC et al. | Antiapoptotic agent sphingosine-1-phosphate protects vitrified murine ovarian grafts. | 2014 | Reprod Sci | pmid:23793475 |
| Guo L et al. | Roles of sphingosine-1-phosphate in reproduction. | 2014 | Reprod Sci | pmid:24336672 |
| Gómez-Torres MJ et al. | Metabolites involved in cellular communication among human cumulus-oocyte-complex and sperm during in vitro fertilization. | 2015 | Reprod. Biol. Endocrinol. | pmid:26553294 |
| Hannoun A et al. | Addition of sphingosine-1-phosphate to human oocyte culture medium decreases embryo fragmentation. | 2010 | Reprod. Biomed. Online | pmid:20093086 |
| Tan SJ et al. | Targeted anti-apoptosis activity for ovarian protection against chemotherapy-induced ovarian gonadotoxicity. | 2014 | Reprod. Biomed. Online | pmid:25246113 |
| Singh AT et al. | Sphingosine-sphingosine-1-phosphate pathway regulates trophoblast differentiation and syncytialization. | 2012 | Reprod. Biomed. Online | pmid:22197131 |
| Kalo D and Roth Z | Involvement of the sphingolipid ceramide in heat-shock-induced apoptosis of bovine oocytes. | 2011 | Reprod. Fertil. Dev. | pmid:21871207 |
| Ali A and Sirard MA | Protein kinases influence bovine oocyte competence during short-term treatment with recombinant human follicle stimulating hormone. | 2005 | Reproduction | pmid:16123237 |
| Roth Z and Hansen PJ | Disruption of nuclear maturation and rearrangement of cytoskeletal elements in bovine oocytes exposed to heat shock during maturation. | 2005 | Reproduction | pmid:15695618 |
| Gendron D et al. | Treatment with a sphingosine analog after the inception of house dust mite-induced airway inflammation alleviates key features of experimental asthma. | 2015 | Respir. Res. | pmid:25645346 |
| Terashita T et al. | Administration of JTE013 abrogates experimental asthma by regulating proinflammatory cytokine production from bronchial epithelial cells. | 2016 | Respir. Res. | pmid:27829417 |
| Pfaff M et al. | Activation of the SPHK/S1P signalling pathway is coupled to muscarinic receptor-dependent regulation of peripheral airways. | 2005 | Respir. Res. | pmid:15927078 |
| Barnawi J et al. | Reduced DNA methylation of sphingosine-1 phosphate receptor 5 in alveolar macrophages in COPD: A potential link to failed efferocytosis. | 2017 | Respirology | pmid:27868302 |
| Fontoura P and Garren H | Multiple sclerosis therapies: molecular mechanisms and future. | 2010 | Results Probl Cell Differ | pmid:20838962 |
| Illana Esteban C | [Cordyceps sinensis, a fungi used in the Chinese traditional medicine]. | 2007 | Rev Iberoam Micol | pmid:18095756 |
| GarcÃa-Merino JA and Sánchez AJ | [Basic mechanisms of action of fingolimod in relation to multiple sclerosis]. | 2012 | Rev Neurol | pmid:22718407 |
| Cruz VT and Fonseca J | Central effects of fingolimod. | 2014 | Rev Neurol | pmid:25030072 |
| Varo-Sánchez GM et al. | [Pharmacological targets in multiple sclerosis]. | 2011 | Rev Neurol | pmid:21678322 |
| Cervera C | [Infections and fingolimod]. | 2012 | Rev Neurol | pmid:22829086 |
| Fernández Ó et al. | [Usefulness of electronic drug registers: Spanish register of patients treated with fingolimod (Gilenya ®)]. | 2014 | Rev Neurol | pmid:24399624 |
| Marriott JJ and O'Connor PW | Emerging therapies in relapsing-remitting multiple sclerosis. | 2010 | Rev Recent Clin Trials | pmid:20500147 |
| Mansoor M and Melendez AJ | Recent trials for FTY720 (fingolimod): a new generation of immunomodulators structurally similar to sphingosine. | 2008 | Rev Recent Clin Trials | pmid:18474015 |
| Carr JM et al. | Sphingosine kinase 1 in viral infections. | 2013 | Rev. Med. Virol. | pmid:22639116 |
| Rivera R and Chun J | Biological effects of lysophospholipids. | 2008 | Rev. Physiol. Biochem. Pharmacol. | pmid:18481029 |
| Kikuta J et al. | S1P-targeted therapy for elderly rheumatoid arthritis patients with osteoporosis. | 2011 | Rheumatol. Int. | pmid:21113810 |
| Chapurlat RD and Confavreux CB | Novel biological markers of bone: from bone metabolism to bone physiology. | 2016 | Rheumatology (Oxford) | pmid:26790456 |
| Yatomi Y | [Elucidation of the functional roles of lysophospholipid mediators and its application in laboratory medicine]. | 2006 | Rinsho Byori | pmid:16913663 |
| Ohkawa R et al. | [Sphingolipids, possible biomarkers for atherosclerotic disorders]. | 2013 | Rinsho Byori | pmid:24369591 |
| Kimura T et al. | [Measurement of sphingosine 1-phosphate as a biomarker of atherosclerosis]. | 2007 | Rinsho Byori | pmid:17511266 |
| Fujii S | [Atherosclerosis, Chronic Inflammation, and Thrombosis: In Search of the Missing Link in Laboratory Medicine]. | 2015 | Rinsho Byori | pmid:26524900 |
| Shichita T et al. | [Role of T lymphocytes in ischemic brain injury]. | 2010 | Rinsho Shinkeigaku | pmid:21921486 |
| Izaki S et al. | [A case of neuromyelitis optica spectrum disorder developing a fulminant course with multiple white-matter lesions following fingolimod treatment]. | 2013 | Rinsho Shinkeigaku | pmid:23892961 |
| Liang S and Connell GJ | Identification of specific inhibitors for a trypanosomatid RNA editing reaction. | 2010 | RNA | pmid:20940340 |
| Janas T et al. | Human tRNA(Sec) associates with HeLa membranes, cell lipid liposomes, and synthetic lipid bilayers. | 2012 | RNA | pmid:23097422 |
| Rüger K et al. | Modulation of IL-33/ST2-TIR and TLR signalling pathway by fingolimod and analogues in immune cells. | 2014 | Scand. J. Immunol. | pmid:25207757 |
sphingosine
sphingosine is a lipid of Sphingolipids (SP) class.
Cross Reference
